PubMed

{beta} Cell-Specific CD4+ T Cell Clonotypes in Peripheral Blood and the Pancreatic Islets Are Distinct.

Li L, He Q, Garland A, Yi Z, Aybar LT, Kepler TB, Frelinger JA, Wang B, Tisch R.

J Immunol. 2009 Dec 1;183(11):7585-7591. Epub 2009 Nov 16.PMID: 19917704 [PubMed - as supplied by publisher]Related articles

Islet lymphocyte subsets in male and female NOD mice are qualitatively similar but quantitatively distinct.

Young EF, Hess PR, Arnold LW, Tisch R, Frelinger JA.

Autoimmunity. 2009;42(8):678-91.PMID: 19886740 [PubMed - in process]Related articles

Suppression of ongoing T cell-mediated autoimmunity by peptide-MHC class II dimer vaccination.

Li L, Yi Z, Wang B, Tisch R.

J Immunol. 2009 Oct 1;183(7):4809-16. Epub 2009 Sep 14.PMID: 19752238 [PubMed - indexed for MEDLINE]Related articles

A novel role for c-Src and STAT3 in apoptotic cell-mediated MerTK-dependent immunoregulation of dendritic cells.

Yi Z, Li L, Matsushima GK, Earp HS, Wang B, Tisch R.

Blood. 2009 Oct 8;114(15):3191-8. Epub 2009 Aug 10.PMID: 19667404 [PubMed - indexed for MEDLINE]Related articles

CD8(+) T cells specific for beta cells encounter their cognate antigens in the islets of NOD mice.

Pang S, Zhang L, Wang H, Yi Z, Li L, Gao L, Zhao J, Tisch R, Katz JD, Wang B.

Eur J Immunol. 2009 Oct;39(10):2716-24.PMID: 19658094 [PubMed - indexed for MEDLINE]Related articles

Cellular immune response to cryptic epitopes during therapeutic gene transfer.

Li C, Goudy K, Hirsch M, Asokan A, Fan Y, Alexander J, Sun J, Monahan P, Seiber D, Sidney J, Sette A, Tisch R, Frelinger J, Samulski RJ.

Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10770-4. Epub 2009 Jun 16.PMID: 19541644 [PubMed - indexed for MEDLINE]Related articles

Cytotoxic-T-lymphocyte-mediated elimination of target cells transduced with engineered adeno-associated virus type 2 vector in vivo.

Li C, Hirsch M, DiPrimio N, Asokan A, Goudy K, Tisch R, Samulski RJ.

J Virol. 2009 Jul;83(13):6817-24. Epub 2009 Apr 15.PMID: 19369348 [PubMed - indexed for MEDLINE]Related articles

The receptor tyrosine kinase MerTK regulates dendritic cell production of BAFF.

Gohlke PR, Williams JC, Vilen BJ, Dillon SR, Tisch R, Matsushima GK.

Autoimmunity. 2009 Mar;42(3):183-97.PMID: 19301199 [PubMed - indexed for MEDLINE]Related articles

MerTK regulates thymic selection of autoreactive T cells.

Wallet MA, Flores RR, Wang Y, Yi Z, Kroger CJ, Mathews CE, Earp HS, Matsushima G, Wang B, Tisch R.

Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4810-5. Epub 2009 Feb 27.PMID: 19251650 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of plasmacytoid dendritic cells in type 1 diabetes: friend or foe?

Tisch R, Wang B.

Diabetes. 2009 Jan;58(1):12-3. No abstract available. PMID: 19114722 [PubMed - indexed for MEDLINE]Related articlesFree article

Dysrulation of T cell peripheral tolerance in type 1 diabetes.

Tisch R, Wang B.

Adv Immunol. 2008;100:125-49. Review.PMID: 19111165 [PubMed - indexed for MEDLINE]Related articles

Parameters influencing antigen-specific immunotherapy for Type 1 diabetes.

Wang B, Tisch R.

Immunol Res. 2008;42(1-3):246-58.PMID: 19052699 [PubMed - indexed for MEDLINE]Related articles

Immunotherapy of type 1 diabetes.

Li L, Yi Z, Tisch R, Wang B.

Arch Immunol Ther Exp (Warsz). 2008 Jul-Aug;56(4):227-36. Epub 2008 Jul 29. Review.PMID: 18726144 [PubMed - indexed for MEDLINE]Related articles

Gene gun-mediated DNA vaccination enhances antigen-specific immunotherapy at a late preclinical stage of type 1 diabetes in nonobese diabetic mice.

Goudy KS, Wang B, Tisch R.

Clin Immunol. 2008 Oct;129(1):49-57.PMID: 18675592 [PubMed - indexed for MEDLINE]Related articlesFree article

ANCA patients have T cells responsive to complementary PR-3 antigen.

Yang J, Bautz DJ, Lionaki S, Hogan SL, Chin H, Tisch RM, Schmitz JL, Pressler BM, Jennette JC, Falk RJ, Preston GA.

Kidney Int. 2008 Nov;74(9):1159-69. Epub 2008 Jul 2.PMID: 18596726 [PubMed - indexed for MEDLINE]Related articlesFree article

Parameters influencing antigen-specific immunotherapy for type 1 diabetes.

Wang B, Tisch R.

Immunol Res. 2008;41(3):175-87.PMID: 18543112 [PubMed - indexed for MEDLINE]Related articles

T-cell promiscuity in autoimmune diabetes.

Li L, Wang B, Frelinger JA, Tisch R.

Diabetes. 2008 Aug;57(8):2099-106. Epub 2008 May 20.PMID: 18492786 [PubMed - indexed for MEDLINE]Related articlesFree article

On the pathogenicity of autoantigen-specific T-cell receptors.

Burton AR, Vincent E, Arnold PY, Lennon GP, Smeltzer M, Li CS, Haskins K, Hutton J, Tisch RM, Sercarz EE, Santamaria P, Workman CJ, Vignali DA.

Diabetes. 2008 May;57(5):1321-30. Epub 2008 Feb 25.PMID: 18299317 [PubMed - indexed for MEDLINE]Related articlesFree article

B lymphocyte depletion by CD20 monoclonal antibody prevents diabetes in nonobese diabetic mice despite isotype-specific differences in Fc gamma R effector functions.

Xiu Y, Wong CP, Bouaziz JD, Hamaguchi Y, Wang Y, Pop SM, Tisch RM, Tedder TF.

J Immunol. 2008 Mar 1;180(5):2863-75.PMID: 18292508 [PubMed - indexed for MEDLINE]Related articlesFree article

MerTK is required for apoptotic cell-induced T cell tolerance.

Wallet MA, Sen P, Flores RR, Wang Y, Yi Z, Huang Y, Mathews CE, Earp HS, Matsushima G, Wang B, Tisch R.

J Exp Med. 2008 Jan 21;205(1):219-32. Epub 2008 Jan 14.PMID: 18195070 [PubMed - indexed for MEDLINE]Related articlesFree article

Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice.

Bouaziz JD, Yanaba K, Venturi GM, Wang Y, Tisch RM, Poe JC, Tedder TF.

Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20878-83. Epub 2007 Dec 19.PMID: 18093919 [PubMed - indexed for MEDLINE]Related articlesFree article

Alphaviral vector-transduced dendritic cells are successful therapeutic vaccines against neu-overexpressing tumors in wild-type mice.

Moran TP, Burgents JE, Long B, Ferrer I, Jaffee EM, Tisch RM, Johnston RE, Serody JS.

Vaccine. 2007 Sep 4;25(36):6604-12. Epub 2007 Jul 17.PMID: 17675184 [PubMed - indexed for MEDLINE]Related articlesFree article

The type and frequency of immunoregulatory CD4+ T-cells govern the efficacy of antigen-specific immunotherapy in nonobese diabetic mice.

Pop SM, Wong CP, He Q, Wang Y, Wallet MA, Goudy KS, Tisch R.

Diabetes. 2007 May;56(5):1395-402. Epub 2007 Feb 22.PMID: 17317763 [PubMed - indexed for MEDLINE]Related articlesFree article

Identical beta cell-specific CD8(+) T cell clonotypes typically reside in both peripheral blood lymphocyte and pancreatic islets.

Wong CP, Stevens R, Long B, Li L, Wang Y, Wallet MA, Goudy KS, Frelinger JA, Tisch R.

J Immunol. 2007 Feb 1;178(3):1388-95.PMID: 17237386 [PubMed - indexed for MEDLINE]Related articlesFree article

Apoptotic cells induce Mer tyrosine kinase-dependent blockade of NF-kappaB activation in dendritic cells.

Sen P, Wallet MA, Yi Z, Huang Y, Henderson M, Mathews CE, Earp HS, Matsushima G, Baldwin AS Jr, Tisch RM.

Blood. 2007 Jan 15;109(2):653-60. Epub 2006 Sep 28.PMID: 17008547 [PubMed - indexed for MEDLINE]Related articlesFree article

EBV latent membrane protein 2A induces autoreactive B cell activation and TLR hypersensitivity.

Wang H, Nicholas MW, Conway KL, Sen P, Diz R, Tisch RM, Clarke SH.

J Immunol. 2006 Sep 1;177(5):2793-802.PMID: 16920914 [PubMed - indexed for MEDLINE]Related articlesFree article

Lymphopenia-driven CD8(+) T cells are resistant to antigen-induced tolerance in NOD.scid mice.

Long B, Wong CP, Wang Y, Tisch R.

Eur J Immunol. 2006 Aug;36(8):2003-12.PMID: 16821236 [PubMed - indexed for MEDLINE]Related articles

Early autoimmune destruction of islet grafts is associated with a restricted repertoire of IGRP-specific CD8+ T cells in diabetic nonobese diabetic mice.

Wong CP, Li L, Frelinger JA, Tisch R.

J Immunol. 2006 Feb 1;176(3):1637-44.PMID: 16424193 [PubMed - indexed for MEDLINE]Related articlesFree article

Low-avidity CD8lo T cells induced by incomplete antigen stimulation in vivo regulate naive higher avidity CD8hi T cell responses to the same antigen.

Maile R, Pop SM, Tisch R, Collins EJ, Cairns BA, Frelinger JA.

Eur J Immunol. 2006 Feb;36(2):397-410.PMID: 16402405 [PubMed - indexed for MEDLINE]Related articles

Immunotherapy for the prevention and treatment of type 1 diabetes.

Goudy KS, Tisch R.

Int Rev Immunol. 2005 Sep-Dec;24(5-6):307-26. Review.PMID: 16318984 [PubMed - indexed for MEDLINE]Related articles

Immunoregulation of dendritic cells.

Wallet MA, Sen P, Tisch R.

Clin Med Res. 2005 Aug;3(3):166-75. Review.PMID: 16160071 [PubMed - indexed for MEDLINE]Related articlesFree article

Single cell analysis shows decreasing FoxP3 and TGFbeta1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes.

Pop SM, Wong CP, Culton DA, Clarke SH, Tisch R.

J Exp Med. 2005 Apr 18;201(8):1333-46.PMID: 15837817 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IkappaB kinase activity.

Bhattacharyya S, Sen P, Wallet M, Long B, Baldwin AS Jr, Tisch R.

Blood. 2004 Aug 15;104(4):1100-9. Epub 2004 Apr 27.PMID: 15113757 [PubMed - indexed for MEDLINE]Related articlesFree article

Critical roles of tumor necrosis factor-related apoptosis-inducing ligand in type 1 diabetes.

Lamhamedi-Cherradi SE, Zheng S, Tisch RM, Chen YH.

Diabetes. 2003 Sep;52(9):2274-8.PMID: 12941766 [PubMed - indexed for MEDLINE]Related articlesFree article

More stringent conditions of plasmid DNA vaccination are required to protect grafted versus endogenous islets in nonobese diabetic mice.

Seifarth C, Pop S, Liu B, Wong CP, Tisch R.

J Immunol. 2003 Jul 1;171(1):469-76.PMID: 12817032 [PubMed - indexed for MEDLINE]Related articlesFree article

NF-kappa B hyperactivation has differential effects on the APC function of nonobese diabetic mouse macrophages.

Sen P, Bhattacharyya S, Wallet M, Wong CP, Poligone B, Sen M, Baldwin AS Jr, Tisch R.

J Immunol. 2003 Feb 15;170(4):1770-80.PMID: 12574341 [PubMed - indexed for MEDLINE]Related articlesFree article

The preferential ability of B lymphocytes to act as diabetogenic APC in NOD mice depends on expression of self-antigen-specific immunoglobulin receptors.

Silveira PA, Johnson E, Chapman HD, Bui T, Tisch RM, Serreze DV.

Eur J Immunol. 2002 Dec;32(12):3657-66.PMID: 12516557 [PubMed - indexed for MEDLINE]Related articles

L-selectin is not required for T cell-mediated autoimmune diabetes.

Friedline RH, Wong CP, Steeber DA, Tedder TF, Tisch R.

J Immunol. 2002 Mar 15;168(6):2659-66.PMID: 11884430 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevated NF-kappaB activation in nonobese diabetic mouse dendritic cells results in enhanced APC function.

Poligone B, Weaver DJ Jr, Sen P, Baldwin AS Jr, Tisch R.

J Immunol. 2002 Jan 1;168(1):188-96.PMID: 11751962 [PubMed - indexed for MEDLINE]Related articlesFree article

Report from the 1st International NOD Mouse T-Cell Workshop and the follow-up mini-workshop.

Kaufman DL, Tisch R, Sarvetnick N, Chatenoud L, Harrison LC, Haskins K, Quinn A, Sercarz E, Singh B, von Herrath M, Wegmann D, Wen L, Zekzer D.

Diabetes. 2001 Nov;50(11):2459-63. Review.PMID: 11679422 [PubMed - indexed for MEDLINE]Related articlesFree article

Dendritic cell vaccination induces cross-reactive cytotoxic T lymphocytes specific for wild-type and natural variant human immunodeficiency virus type 1 epitopes in HLA-A*0201/Kb transgenic mice.

Abdel-Motal UM, Friedline R, Poligone B, Pogue-Caley RR, Frelinger JA, Tisch R.

Clin Immunol. 2001 Oct;101(1):51-8.PMID: 11580226 [PubMed - indexed for MEDLINE]Related articles

Dendritic cells from nonobese diabetic mice exhibit a defect in NF-kappa B regulation due to a hyperactive I kappa B kinase.

Weaver DJ Jr, Poligone B, Bui T, Abdel-Motal UM, Baldwin AS Jr, Tisch R.

J Immunol. 2001 Aug 1;167(3):1461-8.PMID: 11466366 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasmid DNAs encoding insulin and glutamic acid decarboxylase 65 have distinct effects on the progression of autoimmune diabetes in nonobese diabetic mice.

Weaver DJ Jr, Liu B, Tisch R.

J Immunol. 2001 Jul 1;167(1):586-92.PMID: 11418698 [PubMed - indexed for MEDLINE]Related articlesFree article

A glutamic acid decarboxylase 65-specific Th2 cell clone immunoregulates autoimmune diabetes in nonobese diabetic mice.

Tisch R, Wang B, Atkinson MA, Serreze DV, Friedline R.

J Immunol. 2001 Jun 1;166(11):6925-36.PMID: 11359854 [PubMed - indexed for MEDLINE]Related articlesFree article

Class I major histocompatibility complex anchor substitutions alter the conformation of T cell receptor contacts.

Sharma AK, Kuhns JJ, Yan S, Friedline RH, Long B, Tisch R, Collins EJ.

J Biol Chem. 2001 Jun 15;276(24):21443-9. Epub 2001 Apr 3.PMID: 11287414 [PubMed - indexed for MEDLINE]Related articlesFree article

Antigen-specific mediated suppression of beta cell autoimmunity by plasmid DNA vaccination.

Tisch R, Wang B, Weaver DJ, Liu B, Bui T, Arthos J, Serreze DV.

J Immunol. 2001 Feb 1;166(3):2122-32.PMID: 11160264 [PubMed - indexed for MEDLINE]Related articlesFree article

Distribution and characterization of GFP(+) donor hematogenous cells in Twitcher mice after bone marrow transplantation.

Wu YP, McMahon E, Kraine MR, Tisch R, Meyers A, Frelinger J, Matsushima GK, Suzuki K.

Am J Pathol. 2000 Jun;156(6):1849-54.PMID: 10854208 [PubMed - indexed for MEDLINE]Related articlesFree article

T cell activity after dendritic cell vaccination is dependent on both the type of antigen and the mode of delivery.

Serody JS, Collins EJ, Tisch RM, Kuhns JJ, Frelinger JA.

J Immunol. 2000 May 1;164(9):4961-7.PMID: 10779807 [PubMed - indexed for MEDLINE]Related articlesFree article

Determination of glutamic acid decarboxylase 65 peptides presented by the type I diabetes-associated HLA-DQ8 class II molecule identifies an immunogenic peptide motif.

Herman AE, Tisch RM, Patel SD, Parry SL, Olson J, Noble JA, Cope AP, Cox B, Congia M, McDevitt2 HO.

J Immunol. 1999 Dec 1;163(11):6275-82.PMID: 10570321 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of environmental factors in insulin-dependent diabetes mellitus: an unresolved issue.

Kraine MR, Tisch RM.

Environ Health Perspect. 1999 Oct;107 Suppl 5:777-81. Review.PMID: 10502544 [PubMed - indexed for MEDLINE]Related articlesFree article