PubMed

Skin electroporation: effects on transgene expression, DNA persistence and local tissue environment.

Roos AK, Eriksson F, Timmons JA, Gerhardt J, Nyman U, Gudmundsdotter L, Bråve A, Wahren B, Pisa P.

PLoS One. 2009 Sep 30;4(9):e7226.PMID: 19789652 [PubMed - in process]Related articlesFree article

The importance of brown adipose tissue.

Timmons JA, Pedersen BK.

N Engl J Med. 2009 Jul 23;361(4):415-6; author reply 418-21. No abstract available. PMID: 19625723 [PubMed - indexed for MEDLINE]Related articles

Using functional genomics to study PINK1 and metabolic physiology.

Scheele C, Larsson O, Timmons JA.

Methods Enzymol. 2009;457:211-29.PMID: 19426870 [PubMed - indexed for MEDLINE]Related articles

Systematic analysis of adaptations in aerobic capacity and submaximal energy metabolism provides a unique insight into determinants of human aerobic performance.

Vollaard NB, Constantin-Teodosiu D, Fredriksson K, Rooyackers O, Jansson E, Greenhaff PL, Timmons JA, Sundberg CJ.

J Appl Physiol. 2009 May;106(5):1479-86. Epub 2009 Feb 5.PMID: 19196912 [PubMed - indexed for MEDLINE]Related articles

Polyamines regulate E-cadherin transcription through c-Myc modulating intestinal epithelial barrier function.

Liu L, Guo X, Rao JN, Zou T, Xiao L, Yu T, Timmons JA, Turner DJ, Wang JY.

Am J Physiol Cell Physiol. 2009 Apr;296(4):C801-10. Epub 2009 Jan 28.PMID: 19176757 [PubMed - indexed for MEDLINE]Related articles

Extremely short duration high intensity interval training substantially improves insulin action in young healthy males.

Babraj JA, Vollaard NB, Keast C, Guppy FM, Cottrell G, Timmons JA.

BMC Endocr Disord. 2009 Jan 28;9:3.PMID: 19175906 [PubMed - in process]Related articlesFree article

Dysregulation of mitochondrial dynamics and the muscle transcriptome in ICU patients suffering from sepsis induced multiple organ failure.

Fredriksson K, Tjäder I, Keller P, Petrovic N, Ahlman B, Schéele C, Wernerman J, Timmons JA, Rooyackers O.

PLoS One. 2008;3(11):e3686. Epub 2008 Nov 10. Erratum in: PLoS ONE. 2008;3(12)doi: 10.1371/annotation/68d951f9-a236-472f-98af-24e4cc4c1a20.. PMID: 18997871 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct expression of muscle-specific microRNAs (myomirs) in brown adipocytes.

Walden TB, Timmons JA, Keller P, Nedergaard J, Cannon B.

J Cell Physiol. 2009 Feb;218(2):444-9.PMID: 18937285 [PubMed - indexed for MEDLINE]Related articles

Genomic variants at the PINK1 locus are associated with transcript abundance and plasma nonesterified fatty acid concentrations in European whites.

Franks PW, Scheele C, Loos RJ, Nielsen AR, Finucane FM, Wahlestedt C, Pedersen BK, Wareham NJ, Timmons JA.

FASEB J. 2008 Sep;22(9):3135-45. Epub 2008 May 21.PMID: 18495756 [PubMed - indexed for MEDLINE]Related articlesFree article

Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARgamma agonist.

Petrovic N, Shabalina IG, Timmons JA, Cannon B, Nedergaard J.

Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E287-96. Epub 2008 May 20.PMID: 18492776 [PubMed - indexed for MEDLINE]Related articlesFree article

Commentary on viewpoint: Perspective on the future use of genomics in exercise prescription.

Timmons JA.

J Appl Physiol. 2008 Apr;104(4):1250. No abstract available. PMID: 18385305 [PubMed - indexed for MEDLINE]Related articlesFree article

Using systems biology to define the essential biological networks responsible for adaptation to endurance exercise training.

Keller P, Vollaard N, Babraj J, Ball D, Sewell DA, Timmons JA.

Biochem Soc Trans. 2007 Nov;35(Pt 5):1306-9. Review.PMID: 17956337 [PubMed - indexed for MEDLINE]Related articles

Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration?

Scheele C, Nielsen AR, Walden TB, Sewell DA, Fischer CP, Brogan RJ, Petrovic N, Larsson O, Tesch PA, Wennmalm K, Hutchinson DS, Cannon B, Wahlestedt C, Pedersen BK, Timmons JA.

FASEB J. 2007 Nov;21(13):3653-65. Epub 2007 Jun 12.PMID: 17567565 [PubMed - indexed for MEDLINE]Related articlesFree article

The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function.

Scheele C, Petrovic N, Faghihi MA, Lassmann T, Fredriksson K, Rooyackers O, Wahlestedt C, Good L, Timmons JA.

BMC Genomics. 2007 Mar 15;8:74.PMID: 17362513 [PubMed - indexed for MEDLINE]Related articlesFree article

Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages.

Timmons JA, Wennmalm K, Larsson O, Walden TB, Lassmann T, Petrovic N, Hamilton DL, Gimeno RE, Wahlestedt C, Baar K, Nedergaard J, Cannon B.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4401-6. Epub 2007 Mar 5.PMID: 17360536 [PubMed - indexed for MEDLINE]Related articlesFree article

Does everything now make (anti)sense?

Timmons JA, Good L.

Biochem Soc Trans. 2006 Dec;34(Pt 6):1148-50.PMID: 17073772 [PubMed - indexed for MEDLINE]Related articles

Chronic treatment with the beta(2)-adrenoceptor agonist prodrug BRL-47672 impairs rat skeletal muscle function by inducing a comprehensive shift to a faster muscle phenotype.

Baker DJ, Constantin-Teodosiu D, Jones SW, Timmons JA, Greenhaff PL.

J Pharmacol Exp Ther. 2006 Oct;319(1):439-46. Epub 2006 Jul 14.PMID: 16844843 [PubMed - indexed for MEDLINE]Related articlesFree article

The experimental type 2 diabetes therapy glycogen phosphorylase inhibition can impair aerobic muscle function during prolonged contraction.

Baker DJ, Greenhaff PL, MacInnes A, Timmons JA.

Diabetes. 2006 Jun;55(6):1855-61.PMID: 16731853 [PubMed - indexed for MEDLINE]Related articlesFree article

Oligonucleotide microarray expression profiling: human skeletal muscle phenotype and aerobic exercise training.

Timmons JA, Sundberg CJ.

IUBMB Life. 2006 Jan;58(1):15-24. Review. Erratum in: IUBMB Life. 2006 Feb;58(2):117. PMID: 16540428 [PubMed - indexed for MEDLINE]Related articles

Expression profiling following local muscle inactivity in humans provides new perspective on diabetes-related genes.

Timmons JA, Norrbom J, Schéele C, Thonberg H, Wahlestedt C, Tesch P.

Genomics. 2006 Jan;87(1):165-72. Epub 2005 Dec 2.PMID: 16326070 [PubMed - indexed for MEDLINE]Related articles

Modulation of extracellular matrix genes reflects the magnitude of physiological adaptation to aerobic exercise training in humans.

Timmons JA, Jansson E, Fischer H, Gustafsson T, Greenhaff PL, Ridden J, Rachman J, Sundberg CJ.

BMC Biol. 2005 Sep 2;3:19.PMID: 16138928 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycogen phosphorylase inhibition in type 2 diabetes therapy: a systematic evaluation of metabolic and functional effects in rat skeletal muscle.

Baker DJ, Timmons JA, Greenhaff PL.

Diabetes. 2005 Aug;54(8):2453-9.PMID: 16046314 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic adaptations to repeated periods of contraction with reduced blood flow in canine skeletal muscle.

MacInnes A, Timmons JA.

BMC Physiol. 2005 Jul 14;5:11.PMID: 16018808 [PubMed - indexed for MEDLINE]Related articlesFree article

Considerations when using the significance analysis of microarrays (SAM) algorithm.

Larsson O, Wahlestedt C, Timmons JA.

BMC Bioinformatics. 2005 May 29;6:129.PMID: 15921534 [PubMed - indexed for MEDLINE]Related articlesFree article

Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy.

Timmons JA, Larsson O, Jansson E, Fischer H, Gustafsson T, Greenhaff PL, Ridden J, Rachman J, Peyrard-Janvid M, Wahlestedt C, Sundberg CJ.

FASEB J. 2005 May;19(7):750-60.PMID: 15857889 [PubMed - indexed for MEDLINE]Related articlesFree article

VEGF-A splice variants and related receptor expression in human skeletal muscle following submaximal exercise.

Gustafsson T, Ameln H, Fischer H, Sundberg CJ, Timmons JA, Jansson E.

J Appl Physiol. 2005 Jun;98(6):2137-46. Epub 2005 Jan 20.PMID: 15661835 [PubMed - indexed for MEDLINE]Related articlesFree article

Chasing the "ghost" of the acetyl group deficit.

Timmons JA.

Med Sci Sports Exerc. 2005 Jan;37(1):162; author reply 163. No abstract available. PMID: 15632683 [PubMed - indexed for MEDLINE]Related articles

Acetyl group availability influences phosphocreatine degradation even during intense muscle contraction.

Timmons JA, Constantin-Teodosiu D, Poucher SM, Greenhaff PL.

J Physiol. 2004 Dec 15;561(Pt 3):851-9. Epub 2004 Oct 21.PMID: 15498812 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of the beta2-adrenoceptor agonist prodrug BRL-47672 on cardiovascular function, skeletal muscle myosin heavy chain, and MyoD expression in the rat.

Jones SW, Baker DJ, Gardiner SM, Bennett T, Timmons JA, Greenhaff PL.

J Pharmacol Exp Ther. 2004 Dec;311(3):1225-31. Epub 2004 Jul 8.PMID: 15243031 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic inertia in contracting skeletal muscle: a novel approach for pharmacological intervention in peripheral vascular disease.

Greenhaff PL, Campbell-O'Sullivan SP, Constantin-Teodosiu D, Poucher SM, Roberts PA, Timmons JA.

Br J Clin Pharmacol. 2004 Mar;57(3):237-43. Review.PMID: 14998419 [PubMed - indexed for MEDLINE]Related articlesFree article

Patterns of use of an emergency department-based observation unit.

Hostetler B, Leikin JB, Timmons JA, Hanashiro PK, Kissane K.

Am J Ther. 2002 Nov-Dec;9(6):499-502.PMID: 12424507 [PubMed - indexed for MEDLINE]Related articles

An acetyl group deficit limits mitochondrial ATP production at the onset of exercise.

Greenhaff PL, Campbell-O'Sullivan SP, Constantin-Teodosiu D, Poucher SM, Roberts PA, Timmons JA.

Biochem Soc Trans. 2002 Apr;30(2):275-80. Review.PMID: 12023864 [PubMed - indexed for MEDLINE]Related articles

Can we "switch" the emphasis please?

Timmons JA.

J Appl Physiol. 2002 May;92(5):2221. No abstract available. PMID: 12008647 [PubMed - indexed for MEDLINE]Related articlesFree article

Observation unit evaluation of low risk drug-related chest pain.

Tijunelis MA, Hanashiro P, Kissane K, Leikin JB, Timmons JA, Hryhorczuk DO.

Am J Emerg Med. 2001 Oct;19(6):533-4. No abstract available. PMID: 11593486 [PubMed - indexed for MEDLINE]Related articles

Use of beta-hydroxybutyric acid levels in the emergency department.

Timmons JA, Myer P, Maturen A, Webster R, Schaller E, Leikin J, Barkin R.

Am J Ther. 1998 May;5(3):159-63.PMID: 10099054 [PubMed - indexed for MEDLINE]Related articles

Pyruvate dehydrogenase complex activation status and acetyl group availability as a site of interchange between anaerobic and oxidative metabolism during intense exercise.

Greenhaff PL, Timmons JA.

Adv Exp Med Biol. 1998;441:287-98. Review.PMID: 9781334 [PubMed - indexed for MEDLINE]Related articles

Interaction between aerobic and anaerobic metabolism during intense muscle contraction.

Greenhaff PL, Timmons JA.

Exerc Sport Sci Rev. 1998;26:1-30. Review. No abstract available. PMID: 9696983 [PubMed - indexed for MEDLINE]Related articles

Regulation of skeletal muscle carbohydrate oxidation during steady-state contraction.

Timmons JA, Poucher SM, Constantin-Teodosiu D, Macdonald IA, Greenhaff PL.

Am J Physiol. 1998 May;274(5 Pt 2):R1384-9.PMID: 9612406 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle acetyl group availability is a major determinant of oxygen deficit in humans during submaximal exercise.

Timmons JA, Gustafsson T, Sundberg CJ, Jansson E, Greenhaff PL.

Am J Physiol. 1998 Feb;274(2 Pt 1):E377-80.PMID: 9486171 [PubMed - indexed for MEDLINE]Related articlesFree article

Substrate availability limits human skeletal muscle oxidative ATP regeneration at the onset of ischemic exercise.

Timmons JA, Gustafsson T, Sundberg CJ, Jansson E, Hultman E, Kaijser L, Chwalbinska-Moneta J, Constantin-Teodosiu D, Macdonald IA, Greenhaff PL.

J Clin Invest. 1998 Jan 1;101(1):79-85.PMID: 9421469 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic responses from rest to steady state determine contractile function in ischemic skeletal muscle.

Timmons JA, Poucher SM, Constantin-Teodosiu D, Macdonald IA, Greenhaff PL.

Am J Physiol. 1997 Aug;273(2 Pt 1):E233-8.PMID: 9277374 [PubMed - indexed for MEDLINE]Related articles

Muscle creatine loading in men.

Hultman E, Söderlund K, Timmons JA, Cederblad G, Greenhaff PL.

J Appl Physiol. 1996 Jul;81(1):232-7.PMID: 8828669 [PubMed - indexed for MEDLINE]Related articles

Submaximal running economy in run-trained pre-pubertal boys.

Unnithan VB, Timmons JA, Brogan RT, Paton JY, Rowland TW.

J Sports Med Phys Fitness. 1996 Mar;36(1):16-23.PMID: 8699833 [PubMed - indexed for MEDLINE]Related articles

Metabolic responses of canine gracilis muscle during contraction with partial ischemia.

Timmons JA, Poucher SM, Constantin-Teodosiu D, Worrall V, MacDonald IA, Greenhaff PL.

Am J Physiol. 1996 Mar;270(3 Pt 1):E400-6.PMID: 8638684 [PubMed - indexed for MEDLINE]Related articles

Increased acetyl group availability enhances contractile function of canine skeletal muscle during ischemia.

Timmons JA, Poucher SM, Constantin-Teodosiu D, Worrall V, Macdonald IA, Greenhaff PL.

J Clin Invest. 1996 Feb 1;97(3):879-83.PMID: 8609248 [PubMed - indexed for MEDLINE]Related articlesFree article

Physiologic correlates to running performance in pre-pubertal distance runners.

Unnithan VB, Timmons JA, Paton JY, Rowland TW.

Int J Sports Med. 1995 Nov;16(8):528-33.PMID: 8776207 [PubMed - indexed for MEDLINE]Related articles

Reply to "Comment on 'Anisotropic growth of twinned cubic crystals' "

Jagannathan R, Mehta RV, Timmons JA, Black DL.

Phys Rev B Condens Matter. 1995 Apr 1;51(13):8655. No abstract available. PMID: 9977493 [PubMed - as supplied by publisher]Related articles

Reproducibility of cardiorespiratory measurements during submaximal and maximal running in children.

Unnithan VB, Murray LA, Timmons JA, Buchanan D, Paton JY.

Br J Sports Med. 1995 Mar;29(1):66-71.PMID: 7788223 [PubMed - indexed for MEDLINE]Related articlesFree article

Validation of the sensormedics (S2900Z) metabolic cart for pediatric exercise testing.

Unnithan VB, Wilson J, Buchanan D, Timmons JA, Paton JY.

Can J Appl Physiol. 1994 Dec;19(4):472-9.PMID: 7849663 [PubMed - indexed for MEDLINE]Related articles

Anisotropic growth of twinned cubic crystals.

Jagannathan R, Mehta RV, Timmons JA, Black DL.

Phys Rev B Condens Matter. 1993 Nov 1;48(18):13261-13265. No abstract available. PMID: 10007717 [PubMed - as supplied by publisher]Related articles