PubMed

Plasma pharmacokinetics of alkylresorcinol metabolites: new candidate biomarkers for whole-grain rye and wheat intake.

Söderholm PP, Koskela AH, Lundin JE, Tikkanen MJ, Adlercreutz HC.

Am J Clin Nutr. 2009 Nov;90(5):1167-71. Epub 2009 Sep 16.PMID: 19759167 [PubMed - in process]Related articles

Plasma triglycerides and cardiovascular events in the Treating to New Targets and Incremental Decrease in End-Points through Aggressive Lipid Lowering trials of statins in patients with coronary artery disease.

Faergeman O, Holme I, Fayyad R, Bhatia S, Grundy SM, Kastelein JJ, LaRosa JC, Larsen ML, Lindahl C, Olsson AG, Tikkanen MJ, Waters DD, Pedersen TR; Steering Committees of IDEAL and TNT Trials.

Am J Cardiol. 2009 Aug 15;104(4):459-63. Epub 2009 Jun 24.PMID: 19660594 [PubMed - indexed for MEDLINE]Related articles

Biochemical markers for cardiovascular disease in recently postmenopausal women with or without hot flashes.

Tuomikoski P, Mikkola TS, Hämäläinen E, Tikkanen MJ, Turpeinen U, Ylikorkala O.

Menopause. 2009 Jul 13. [Epub ahead of print]PMID: 19602991 [PubMed - as supplied by publisher]Related articles

HDL-associated dehydroepiandrosterone fatty acyl esters: enhancement of vasodilatory effect of HDL.

Paatela H, Mervaala E, Deb S, Wähälä K, Tikkanen MJ.

Steroids. 2009 Oct;74(10-11):814-8. Epub 2009 May 15.PMID: 19447125 [PubMed - in process]Related articles

Comparative effect of atorvastatin (80 mg) versus simvastatin (20 to 40 mg) in preventing hospitalizations for heart failure in patients with previous myocardial infarction.

Strandberg TE, Holme I, Faergeman O, Kastelein JJ, Lindahl C, Larsen ML, Olsson AG, Pedersen TR, Tikkanen MJ; IDEAL Study Group.

Am J Cardiol. 2009 May 15;103(10):1381-5. Epub 2009 Mar 25.PMID: 19427432 [PubMed - indexed for MEDLINE]Related articles

Human macrophage cholesterol efflux potential is enhanced by HDL-associated 17beta-estradiol fatty acyl esters.

Badeau RM, Metso J, Wähälä K, Tikkanen MJ, Jauhiainen M.

J Steroid Biochem Mol Biol. 2009 Aug;116(1-2):44-9. Epub 2009 May 3.PMID: 19406243 [PubMed - indexed for MEDLINE]Related articles

Congestive heart failure is associated with lipoprotein components in statin-treated patients with coronary heart disease Insights from the Incremental Decrease in End points Through Aggressive Lipid Lowering Trial (IDEAL).

Holme I, Strandberg TE, Faergeman O, Kastelein JJ, Olsson AG, Tikkanen MJ, Larsen ML, Lindahl C, Pedersen TR; Incremental Decrease in End Points Through Aggressive Lipid Lowering Study Group.

Atherosclerosis. 2009 Aug;205(2):522-7. Epub 2009 Jan 24.PMID: 19327776 [PubMed - in process]Related articles

Adherence-adjusted efficacy with intensive versus standard statin therapy in patients with acute myocardial infarction in the IDEAL study.

Holme I, Szarek M, Cater NB, Faergeman O, Kastelein JJ, Olsson AG, Tikkanen MJ, Larsen ML, Lindahl C, Pedersen TR; Incremental Decrease in End Points Through Aggressive Lipid Lowering Study Group.

Eur J Cardiovasc Prev Rehabil. 2009 Jun;16(3):315-20.PMID: 19322096 [PubMed - indexed for MEDLINE]Related articles

Comparison of efficacy and safety of atorvastatin (80 mg) to simvastatin (20 to 40 mg) in patients aged <65 versus >or=65 years with coronary heart disease (from the Incremental DEcrease through Aggressive Lipid Lowering [IDEAL] study).

Tikkanen MJ, Holme I, Cater NB, Szarek M, Faergeman O, Kastelein JJ, Olsson AG, Larsen ML, Lindahl C, Pedersen TR; Incremental DEcrease through Aggressive Lipid Lowering Investigators.

Am J Cardiol. 2009 Mar 1;103(5):577-82. Epub 2009 Jan 17.PMID: 19231315 [PubMed - indexed for MEDLINE]Related articles

Lipoprotein predictors of cardiovascular events in statin-treated patients with coronary heart disease. Insights from the Incremental Decrease In End-points Through Aggressive Lipid-lowering Trial (IDEAL).

Holme I, Cater NB, Faergeman O, Kastelein JJ, Olsson AG, Tikkanen MJ, Larsen ML, Lindahl C, Pedersen TR; Incremental Decrease in End-Points Through Aggressive Lipid-Lowering (IDEAL) Study Group.

Ann Med. 2008;40(6):456-64.PMID: 19160529 [PubMed - indexed for MEDLINE]Related articles

Role of lysosomal acid lipase in the intracellular metabolism of LDL-transported dehydroepiandrosterone-fatty acyl esters.

Wang F, Wang W, Wähälä K, Adlercreutz H, Ikonen E, Tikkanen MJ.

Am J Physiol Endocrinol Metab. 2008 Dec;295(6):E1455-61. Epub 2008 Sep 16.PMID: 18796546 [PubMed - indexed for MEDLINE]Related articlesFree article

Soy-tibolone combination - effect on lipids in postmenopausal monkeys and women.

Appt SE, Törmälä R, Franke AA, Mikkola TS, Tikkanen MJ, Ylikorkala O, Clarkson TB.

Maturitas. 2008 Jul-Aug;60(3-4):216-22. Epub 2008 Aug 8.PMID: 18687539 [PubMed - indexed for MEDLINE]Related articlesFree article

Steroid hormone-fatty acid esters and bone.

Badeau MH, Badeau R, Jauhiainen M, Tikkanen MJ.

J Bone Miner Res. 2008 Nov;23(11):1866-7. No abstract available. PMID: 18665792 [PubMed - indexed for MEDLINE]Related articles

Safety assessment of common foods enriched with natural nonesterified plant sterols.

Tuomilehto J, Tikkanen MJ, Högström P, Keinänen-Kiukaanniemi S, Piironen V, Toivo J, Salonen JT, Nyyssönen K, Stenman UH, Alfthan H, Karppanen H.

Eur J Clin Nutr. 2009 May;63(5):684-91. Epub 2008 Feb 13.PMID: 18270526 [PubMed - indexed for MEDLINE]Related articles

High-density lipoprotein cholesterol, high-density lipoprotein particle size, and apolipoprotein A-I: significance for cardiovascular risk: the IDEAL and EPIC-Norfolk studies.

van der Steeg WA, Holme I, Boekholdt SM, Larsen ML, Lindahl C, Stroes ES, Tikkanen MJ, Wareham NJ, Faergeman O, Olsson AG, Pedersen TR, Khaw KT, Kastelein JJ.

J Am Coll Cardiol. 2008 Feb 12;51(6):634-42.PMID: 18261682 [PubMed - indexed for MEDLINE]Related articles

Individual differences in equol production capability modulate blood pressure in tibolone-treated postmenopausal women: lack of effect of soy supplementation.

Törmälä RM, Appt S, Clarkson TB, Tikkanen MJ, Ylikorkala O, Mikkola TS.

Climacteric. 2007 Dec;10(6):471-9.PMID: 18049940 [PubMed - indexed for MEDLINE]Related articles

High-density lipoprotein-associated 17beta-estradiol fatty acyl ester uptake by Fu5AH hepatoma cells: implications of the roles of scavenger receptor class B, type I and the low-density lipoprotein receptor.

Badeau RM, Metso J, Tikkanen MJ, Jauhiainen M.

Biochim Biophys Acta. 2007 Oct;1771(10):1329-34. Epub 2007 Sep 7.PMID: 17905649 [PubMed - indexed for MEDLINE]Related articles

[Not Available]

Tikkanen MJ.

Duodecim. 2007;123(12):1433-4. Finnish. No abstract available. PMID: 17726891 [PubMed]Related articles

Estradiol fatty acid esters in adipose tissue and serum of pregnant and pre- and postmenopausal women.

Badeau M, Vihma V, Mikkola TS, Tiitinen A, Tikkanen MJ.

J Clin Endocrinol Metab. 2007 Nov;92(11):4327-31. Epub 2007 Aug 28.PMID: 17726068 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantification of alkylresorcinol metabolites in urine by HPLC with coulometric electrode array detection.

Koskela A, Linko-Parvinen AM, Hiisivuori P, Samaletdin A, Kamal-Eldin A, Tikkanen MJ, Adlercreutz H.

Clin Chem. 2007 Jul;53(7):1380-3. Epub 2007 May 10.PMID: 17495018 [PubMed - indexed for MEDLINE]Related articlesFree article

Alkylresorcinols from whole-grain wheat and rye are transported in human plasma lipoproteins.

Linko-Parvinen AM, Landberg R, Tikkanen MJ, Adlercreutz H, Peñalvo JL.

J Nutr. 2007 May;137(5):1137-42.PMID: 17449571 [PubMed - indexed for MEDLINE]Related articlesFree article

Erectile dysfunction as a risk factor for coronary heart disease: implications for prevention.

Tikkanen MJ, Jackson G, Tammela T, Assmann G, Palomäki A, Kupari M, Olsson A.

Int J Clin Pract. 2007 Feb;61(2):265-8. Review. Erratum in: Int J Clin Pract. 2007 Apr;61(4):711. PMID: 17263713 [PubMed - indexed for MEDLINE]Related articles

Effect of isolated isoflavone supplementation on ABCA1-dependent cholesterol efflux potential in postmenopausal women.

Badeau R, Jauhiainen M, Metso J, Nikander E, Tikkanen MJ, Ylikorkala O, Mikkola TS.

Menopause. 2007 Mar-Apr;14(2):293-9.PMID: 17224860 [PubMed - indexed for MEDLINE]Related articles

Fatty acid esterification of lipoprotein-associated estrone in human plasma and follicular fluid.

Miilunpohja M, Uphoff A, Somerharju P, Tiitinen A, Wähälä K, Tikkanen MJ.

J Steroid Biochem Mol Biol. 2006 Jul;100(1-3):59-66. Epub 2006 May 26.PMID: 16730436 [PubMed - indexed for MEDLINE]Related articles

Plant sterols and stanols.

Tikkanen MJ.

Handb Exp Pharmacol. 2005;(170):215-30. Review.PMID: 16596801 [PubMed - indexed for MEDLINE]Related articles

Safety aspects and cholesterol-lowering efficacy of low fat dairy products containing plant sterols.

Korpela R, Tuomilehto J, Högström P, Seppo L, Piironen V, Salo-Väänänen P, Toivo J, Lamberg-Allardt C, Kärkkäinen M, Outila T, Sundvall J, Vilkkilä S, Tikkanen MJ.

Eur J Clin Nutr. 2006 May;60(5):633-42.PMID: 16404415 [PubMed - indexed for MEDLINE]Related articles

Determination of plasma genistein fatty acid esters following administration of genistein or genistein 4'7-O-dioleate in monkeys.

Badeau M, Tikkanen MJ, Appt SE, Adlercreutz H, Clarkson TB, Hoikkala A, Wähälä K, Mikkola TS.

Biochim Biophys Acta. 2005 Dec 30;1738(1-3):115-20. Epub 2005 Nov 17.PMID: 16326136 [PubMed - indexed for MEDLINE]Related articles

High-dose atorvastatin vs usual-dose simvastatin for secondary prevention after myocardial infarction: the IDEAL study: a randomized controlled trial.

Pedersen TR, Faergeman O, Kastelein JJ, Olsson AG, Tikkanen MJ, Holme I, Larsen ML, Bendiksen FS, Lindahl C, Szarek M, Tsai J; Incremental Decrease in End Points Through Aggressive Lipid Lowering (IDEAL) Study Group.

JAMA. 2005 Nov 16;294(19):2437-45. Erratum in: JAMA. 2005 Dec 28;294(24):3092. PMID: 16287954 [PubMed - indexed for MEDLINE]Related articlesFree article

Estradiol fatty acid esterification is increased in high density lipoprotein subclass 3 isolated from hypertriglyceridemic subjects.

Höckerstedt A, Jauhiainen M, Tikkanen MJ.

Atherosclerosis. 2006 Apr;185(2):264-70. Epub 2005 Aug 18.PMID: 16111685 [PubMed - indexed for MEDLINE]Related articles

Effects of vitamin E on the toxicity of oxidized LDL on endothelial cells in vitro in smokers vs nonsmokers on diets rich in fish.

Seppo L, Lähteenmäki T, Tikkanen MJ, Vanhanen H, Korpela R, Vapaatalo H.

Eur J Clin Nutr. 2005 Nov;59(11):1282-90.PMID: 16047029 [PubMed - indexed for MEDLINE]Related articles

Endurance running ability at adolescence as a predictor of blood pressure levels and hypertension in men: a 25-year follow-up study.

Mikkelsson L, Kaprio J, Kautiainen H, Nupponen H, Tikkanen MJ, Kujala UM.

Int J Sports Med. 2005 Jul-Aug;26(6):448-52.PMID: 16037886 [PubMed - indexed for MEDLINE]Related articles

Estrogen A-ring structure and antioxidative effect on lipoproteins.

Badeau M, Adlercreutz H, Kaihovaara P, Tikkanen MJ.

J Steroid Biochem Mol Biol. 2005 Aug;96(3-4):271-8.PMID: 15993048 [PubMed - indexed for MEDLINE]Related articles

Effects of oral and transdermal estradiol administration on levels of sex hormone-binding globulin in postmenopausal women with and without a history of intrahepatic cholestasis of pregnancy.

Ropponen A, Aittomäki K, Vihma V, Tikkanen MJ, Ylikorkala O.

J Clin Endocrinol Metab. 2005 Jun;90(6):3431-4. Epub 2005 Mar 22.PMID: 15784702 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of 12-month statin therapy on antioxidant potential of LDL and serum antioxidant vitamin concentrations.

Vasankari T, Ahotupa M, Viikari J, Nuotio I, Strandberg T, Vanhanen H, Gylling H, Miettinen T, Tikkanen MJ.

Ann Med. 2004;36(8):618-22.PMID: 15768833 [PubMed - indexed for MEDLINE]Related articles

Effects of statin therapy on circulating conjugated dienes, a measure of LDL oxidation.

Vasankari T, Ahotupa M, Viikari J, Nuotio I, Vuorenmaa T, Strandberg T, Vanhanen H, Tikkanen MJ.

Atherosclerosis. 2005 Mar;179(1):207-9. Epub 2005 Jan 23. No abstract available. PMID: 15721029 [PubMed - indexed for MEDLINE]Related articles

Is there any link between insulin resistance and inflammation in established preeclampsia?

Kaaja R, Laivuori H, Pulkki P, Tikkanen MJ, Hiilesmaa V, Ylikorkala O.

Metabolism. 2004 Nov;53(11):1433-5.PMID: 15536597 [PubMed - indexed for MEDLINE]Related articles

Levels of serum C-reactive protein during oral and transdermal estradiol in postmenopausal women with and without a history of intrahepatic cholestasis of pregnancy.

Ropponen A, Aittomäki K, Tikkanen MJ, Ylikorkala O.

J Clin Endocrinol Metab. 2005 Jan;90(1):142-6. Epub 2004 Nov 2.PMID: 15522941 [PubMed - indexed for MEDLINE]Related articlesFree article

Postmenopausal estrogen therapy and serum estradiol fatty acid esters in women with and without previous intrahepatic cholestasis of pregnancy.

Vihma V, Ropponen A, Aittomäki K, Ylikorkala O, Tikkanen MJ.

Ann Med. 2004;36(5):393-9.PMID: 15478314 [PubMed - indexed for MEDLINE]Related articles

Lecithin/cholesterol acyltransferase induces estradiol esterification in high-density lipoprotein, increasing its antioxidant potential.

Höckerstedt A, Jauhiainen M, Tikkanen MJ.

J Clin Endocrinol Metab. 2004 Oct;89(10):5088-93.PMID: 15472210 [PubMed - indexed for MEDLINE]Related articlesFree article

Design and baseline characteristics of the Incremental Decrease in End Points through Aggressive Lipid Lowering study.

Pedersen TR, Faergeman O, Kastelein JJ, Olsson AG, Tikkanen MJ, Holme I, Larsen ML, Bendiksen FS, Lindahl C, Palmer G; Incremental Decrease in End Points Through Aggressive Lipid Lowering Study Group.

Am J Cardiol. 2004 Sep 15;94(6):720-4.PMID: 15374773 [PubMed - indexed for MEDLINE]Related articles

[Estrogen and cardiovascular diseases]

Mikkola T, Tikkanen MJ.

Duodecim. 2003;119(22):2191-7. Review. Finnish. No abstract available. PMID: 14702808 [PubMed - indexed for MEDLINE]Related articles

Differing effects of oral and transdermal hormone replacement therapy on cardiovascular risk factors in healthy postmenopausal women.

Strandberg TE, Ylikorkala O, Tikkanen MJ.

Am J Cardiol. 2003 Jul 15;92(2):212-4. No abstract available. PMID: 12860228 [PubMed - indexed for MEDLINE]Related articles

Quantitative determination of estradiol fatty acid esters in lipoprotein fractions in human blood.

Vihma V, Tiitinen A, Ylikorkala O, Tikkanen MJ.

J Clin Endocrinol Metab. 2003 Jun;88(6):2552-5.PMID: 12788853 [PubMed - indexed for MEDLINE]Related articlesFree article

A 52-week, multicenter, randomized, parallel-group, double-blind, double-dummy study to assess the efficacy of atorvastatin and simvastatin in reaching low-density lipoprotein cholesterol and triglyceride targets: the treat-to-target (3T) study.

Olsson AG, Eriksson M, Johnson O, Kjellström T, Lanke J, Larsen ML, Pedersen T, Tikkanen MJ, Wiklund O; 3T Study Investigators.

Clin Ther. 2003 Jan;25(1):119-38.PMID: 12637115 [PubMed - indexed for MEDLINE]Related articles

Accumulation of genistein and lipophilic genistein derivatives in lipoproteins during incubation with human plasma in vitro.

Kaamanen M, Adlercreutz H, Jauhiainen M, Tikkanen MJ.

Biochim Biophys Acta. 2003 Mar 17;1631(2):147-52.PMID: 12633680 [PubMed - indexed for MEDLINE]Related articles

Differential effects of oral and transdermal estradiol treatment on circulating estradiol fatty acid ester concentrations in postmenopausal women.

Vihma V, Vehkavaara S, Yki-Järvinen H, Hohtari H, Tikkanen MJ.

J Clin Endocrinol Metab. 2003 Feb;88(2):588-93.PMID: 12574185 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipoprotein-associated estrogens.

Tikkanen MJ, Vihma V, Jauhiainen M, Höckerstedt A, Helisten H, Kaamanen M.

Cardiovasc Res. 2002 Nov;56(2):184-8. Review.PMID: 12393088 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipophilic oestrogen derivatives contained in lipoprotein particles.

Tikkanen MJ, Vihma V, Höckerstedt A, Jauhiainen M, Helisten H, Kaamanen M.

Acta Physiol Scand. 2002 Oct;176(2):117-21.PMID: 12354171 [PubMed - indexed for MEDLINE]Related articles

[Hypertension in postmenopausal women]

Kaaja RJ, Tikkanen MJ.

Duodecim. 2002;118(1):25-30. Review. Finnish. No abstract available. PMID: 12228993 [PubMed - indexed for MEDLINE]Related articles

[Menopausal and post-menopausal hormonal replacement therapy in the prevention of cardiovascular diseases]

Tiitinen A, Tikkanen MJ.

Duodecim. 1999;115(20):2205-9. Review. Finnish. No abstract available. PMID: 11973923 [PubMed - indexed for MEDLINE]Related articles