PubMed

Portal pressure responses and angiotensin peptide production in rat liver are determined by relative activity of ACE and ACE2.

Herath CB, Lubel JS, Jia Z, Velkoska E, Casley D, Brown L, Tikellis C, Burrell LM, Angus PW.

Am J Physiol Gastrointest Liver Physiol. 2009 Jul;297(1):G98-G106. Epub 2009 Apr 23.PMID: 19389807 [PubMed - indexed for MEDLINE]Related articles

Hyperglycemia induces a dynamic cooperativity of histone methylase and demethylase enzymes associated with gene-activating epigenetic marks that coexist on the lysine tail.

Brasacchio D, Okabe J, Tikellis C, Balcerczyk A, George P, Baker EK, Calkin AC, Brownlee M, Cooper ME, El-Osta A.

Diabetes. 2009 May;58(5):1229-36. Epub 2009 Feb 10.PMID: 19208907 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative gene expression analysis in kidney tissues.

Tikellis C, Koh P, Burns W, Kantharidis P.

Methods Mol Biol. 2009;466:83-107.PMID: 19148599 [PubMed - indexed for MEDLINE]Related articles

Direct antiatherosclerotic effects of PPAR agonists.

Jandeleit-Dahm KA, Calkin A, Tikellis C, Thomas M.

Curr Opin Lipidol. 2009 Feb;20(1):24-9. Review.PMID: 19133407 [PubMed - indexed for MEDLINE]Related articles

Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs.

Tikellis C, Thomas MC, Harcourt BE, Coughlan MT, Pete J, Bialkowski K, Tan A, Bierhaus A, Cooper ME, Forbes JM.

Am J Physiol Endocrinol Metab. 2008 Aug;295(2):E323-30. Epub 2008 May 13.PMID: 18477705 [PubMed - indexed for MEDLINE]Related articlesFree article

Advances in the renin-angiotensin-aldosterone system: relevance to diabetic nephropathy.

Koitka A, Tikellis C.

ScientificWorldJournal. 2008 Apr 20;8:434-45. Review.PMID: 18454253 [PubMed - indexed for MEDLINE]Related articles

Angiotensin converting enzyme 2 in the kidney.

Koitka A, Cooper ME, Thomas MC, Tikellis C.

Clin Exp Pharmacol Physiol. 2008 Apr;35(4):420-5. Review.PMID: 18307733 [PubMed - indexed for MEDLINE]Related articles

Functional angiotensin II type 2 receptors inhibit growth factor signaling in LNCaP and PC3 prostate cancer cell lines.

Chow L, Rezmann L, Imamura K, Wang L, Catt K, Tikellis C, Louis WJ, Frauman AG, Louis SN.

Prostate. 2008 May 1;68(6):651-60.PMID: 18288685 [PubMed - indexed for MEDLINE]Related articles

ACE2 deficiency modifies renoprotection afforded by ACE inhibition in experimental diabetes.

Tikellis C, Bialkowski K, Pete J, Sheehy K, Su Q, Johnston C, Cooper ME, Thomas MC.

Diabetes. 2008 Apr;57(4):1018-25. Epub 2008 Jan 30.PMID: 18235039 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced plaque formation induced by rosiglitazone in an STZ-diabetes mouse model of atherosclerosis is associated with downregulation of adhesion molecules.

Tikellis C, Jandeleit-Dahm KA, Sheehy K, Murphy A, Chin-Dusting J, Kling D, Sebokova E, Cooper ME, Mizrahi J, Woollard KJ.

Atherosclerosis. 2008 Jul;199(1):55-64. Epub 2008 Feb 21.PMID: 18093596 [PubMed - indexed for MEDLINE]Related articles

PPARs and diabetes-associated atherosclerosis.

Calkin AC, Jandeleit-Dahm KA, Sebekova E, Allen TJ, Mizrahi J, Cooper ME, Tikellis C.

Curr Pharm Des. 2007;13(26):2736-41. Review.PMID: 17897018 [PubMed - indexed for MEDLINE]Related articles

Increased atherosclerosis following treatment with a dual PPAR agonist in the ApoE knockout mouse.

Calkin AC, Allen TJ, Lassila M, Tikellis C, Jandeleit-Dahm KA, Thomas MC.

Atherosclerosis. 2007 Nov;195(1):17-22. Epub 2007 Jan 9.PMID: 17214990 [PubMed - indexed for MEDLINE]Related articles

Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: implications for diabetic renal disease.

Burns WC, Twigg SM, Forbes JM, Pete J, Tikellis C, Thallas-Bonke V, Thomas MC, Cooper ME, Kantharidis P.

J Am Soc Nephrol. 2006 Sep;17(9):2484-94. Epub 2006 Aug 16.PMID: 16914537 [PubMed - indexed for MEDLINE]Related articlesFree article

Developmental expression of ACE2 in the SHR kidney: a role in hypertension?

Tikellis C, Cooper ME, Bialkowski K, Johnston CI, Burns WC, Lew RA, Smith AI, Thomas MC.

Kidney Int. 2006 Jul;70(1):34-41. Epub 2006 May 17.PMID: 16710353 [PubMed - indexed for MEDLINE]Related articles

Preventing diabetes in patients with hypertension: one more reason to block the renin-angiotensin system.

Cooper ME, Tikellis C, Thomas MC.

J Hypertens Suppl. 2006 Mar;24(1):S57-63. Review.PMID: 16601575 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms in the gene encoding angiotensin I converting enzyme 2 and diabetic nephropathy.

Fröjdö S, Sjölind L, Parkkonen M, Mäkinen VP, Kilpikari R, Pettersson-Fernholm K, Forsblom C, Fagerudd J, Tikellis C, Cooper ME, Wessman M, Groop PH; FinnDiane Study Group.

Diabetologia. 2005 Nov;48(11):2278-81. Epub 2005 Oct 7.PMID: 16211375 [PubMed - indexed for MEDLINE]Related articles

Role of the renin-angiotensin system in the endocrine pancreas: implications for the development of diabetes.

Tikellis C, Cooper ME, Thomas MC.

Int J Biochem Cell Biol. 2006;38(5-6):737-51. Epub 2005 Sep 12. Review.PMID: 16198140 [PubMed - indexed for MEDLINE]Related articles

Chronic liver injury in rats and humans upregulates the novel enzyme angiotensin converting enzyme 2.

Paizis G, Tikellis C, Cooper ME, Schembri JM, Lew RA, Smith AI, Shaw T, Warner FJ, Zuilli A, Burrell LM, Angus PW.

Gut. 2005 Dec;54(12):1790-6. Epub 2005 Sep 15.PMID: 16166274 [PubMed - indexed for MEDLINE]Related articlesFree article

Interactions between renin angiotensin system and advanced glycation in the kidney.

Thomas MC, Tikellis C, Burns WM, Bialkowski K, Cao Z, Coughlan MT, Jandeleit-Dahm K, Cooper ME, Forbes JM.

J Am Soc Nephrol. 2005 Oct;16(10):2976-84. Epub 2005 Aug 17.PMID: 16107577 [PubMed - indexed for MEDLINE]Related articlesFree article

High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction.

Kooptiwut S, Kebede M, Zraika S, Visinoni S, Aston-Mourney K, Favaloro J, Tikellis C, Thomas MC, Forbes JM, Cooper ME, Dunlop M, Proietto J, Andrikopoulos S.

J Mol Endocrinol. 2005 Aug;35(1):39-48.PMID: 16087720 [PubMed - indexed for MEDLINE]Related articlesFree article

Heparanase inhibition reduces proteinuria in a model of accelerated anti-glomerular basement membrane antibody disease.

Levidiotis V, Freeman C, Tikellis C, Cooper ME, Power DA.

Nephrology (Carlton). 2005 Apr;10(2):167-73.PMID: 15877677 [PubMed - indexed for MEDLINE]Related articles

Identification of angiotensin converting enzyme 2 in the rodent retina.

Tikellis C, Johnston CI, Forbes JM, Burns WC, Thomas MC, Lew RA, Yarski M, Smith AI, Cooper ME.

Curr Eye Res. 2004 Dec;29(6):419-27.PMID: 15764086 [PubMed - indexed for MEDLINE]Related articles

Why blockade of the renin-angiotensin system reduces the incidence of new-onset diabetes.

Jandeleit-Dahm KA, Tikellis C, Reid CM, Johnston CI, Cooper ME.

J Hypertens. 2005 Mar;23(3):463-73. Review.PMID: 15716683 [PubMed - indexed for MEDLINE]Related articles

Myocardial infarction increases ACE2 expression in rat and humans.

Burrell LM, Risvanis J, Kubota E, Dean RG, MacDonald PS, Lu S, Tikellis C, Grant SL, Lew RA, Smith AI, Cooper ME, Johnston CI.

Eur Heart J. 2005 Feb;26(4):369-75; discussion 322-4. Epub 2005 Jan 25.PMID: 15671045 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression analysis of the epigenetic methyltransferases and methyl-CpG binding protein families in the normal B-cell and B-cell chronic lymphocytic leukemia (CLL).

Kn H, Bassal S, Tikellis C, El-Osta A.

Cancer Biol Ther. 2004 Oct;3(10):989-94. Epub 2004 Oct 2.PMID: 15467427 [PubMed - indexed for MEDLINE]Related articles

The role of advanced glycation in reduced organic cation transport associated with experimental diabetes.

Thomas MC, Tikellis C, Kantharidis P, Burns WC, Cooper ME, Forbes JM.

J Pharmacol Exp Ther. 2004 Nov;311(2):456-66. Epub 2004 Jun 22.PMID: 15213250 [PubMed - indexed for MEDLINE]Related articlesFree article

ACE2, a new regulator of the renin-angiotensin system.

Burrell LM, Johnston CI, Tikellis C, Cooper ME.

Trends Endocrinol Metab. 2004 May-Jun;15(4):166-9. Review.PMID: 15109615 [PubMed - indexed for MEDLINE]Related articles

Improved islet morphology after blockade of the renin- angiotensin system in the ZDF rat.

Tikellis C, Wookey PJ, Candido R, Andrikopoulos S, Thomas MC, Cooper ME.

Diabetes. 2004 Apr;53(4):989-97.PMID: 15047614 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel hexad repeats conserved in a putative transporter with restricted expression in cell types associated with growth, calcium exchange and homeostasis.

Brasier G, Tikellis C, Xuereb L, Craigie J, Casley D, Kovacs CS, Fudge NJ, Kalnins R, Cooper ME, Wookey PJ.

Exp Cell Res. 2004 Feb 1;293(1):31-42.PMID: 14729055 [PubMed - indexed for MEDLINE]Related articles

Heparanase is involved in the pathogenesis of proteinuria as a result of glomerulonephritis.

Levidiotis V, Freeman C, Tikellis C, Cooper ME, Power DA.

J Am Soc Nephrol. 2004 Jan;15(1):68-78.PMID: 14694159 [PubMed - indexed for MEDLINE]Related articlesFree article

Connective tissue growth factor is up-regulated in the diabetic retina: amelioration by angiotensin-converting enzyme inhibition.

Tikellis C, Cooper ME, Twigg SM, Burns WC, Tolcos M.

Endocrinology. 2004 Feb;145(2):860-6. Epub 2003 Oct 30.PMID: 14592956 [PubMed - indexed for MEDLINE]Related articlesFree article

Amylin in the periphery.

Wookey PJ, Xuereb L, Tikellis C, Cooper ME.

ScientificWorldJournal. 2003 Mar 24;3:163-75. Review.PMID: 12806128 [PubMed - indexed for MEDLINE]Related articles

Reduced tubular cation transport in diabetes: prevented by ACE inhibition.

Thomas MC, Tikellis C, Burns WC, Thallas V, Forbes JM, Cao Z, Osicka TM, Russo LM, Jerums G, Ghabrial H, Cooper ME, Kantharidis P.

Kidney Int. 2003 Jun;63(6):2152-61.PMID: 12753302 [PubMed - indexed for MEDLINE]Related articles

Regulation of angiotensin II receptors in the prostate of the transgenic (mRen-2)27 rat: effect of angiotensin-converting enzyme inhibition.

Fabiani ME, Hawkes DJ, Frauman AG, Tikellis C, Johnston CI, Wilkinson-Berka JL.

Int J Biochem Cell Biol. 2003 Jun;35(6):973-83.PMID: 12676181 [PubMed - indexed for MEDLINE]Related articles

Calcitonin receptor isoforms expressed in the developing rat kidney.

Tikellis C, Xuereb L, Casley D, Brasier G, Cooper ME, Wookey PJ.

Kidney Int. 2003 Feb;63(2):416-26.PMID: 12631107 [PubMed - indexed for MEDLINE]Related articles

Characterization of renal angiotensin-converting enzyme 2 in diabetic nephropathy.

Tikellis C, Johnston CI, Forbes JM, Burns WC, Burrell LM, Risvanis J, Cooper ME.

Hypertension. 2003 Mar;41(3):392-7. Epub 2003 Feb 24.PMID: 12623933 [PubMed - indexed for MEDLINE]Related articlesFree article

A breaker of advanced glycation end products attenuates diabetes-induced myocardial structural changes.

Candido R, Forbes JM, Thomas MC, Thallas V, Dean RG, Burns WC, Tikellis C, Ritchie RH, Twigg SM, Cooper ME, Burrell LM.

Circ Res. 2003 Apr 18;92(7):785-92. Epub 2003 Mar 6.PMID: 12623881 [PubMed - indexed for MEDLINE]Related articlesFree article

Ontogeny of calcitonin receptor mRNA and protein in the developing central nervous system of the rat.

Tolcos M, Tikellis C, Rees S, Cooper M, Wookey P.

J Comp Neurol. 2003 Jan 27;456(1):29-38.PMID: 12508311 [PubMed - indexed for MEDLINE]Related articles

Up-regulation of components of the renin-angiotensin system in the bile duct-ligated rat liver.

Paizis G, Cooper ME, Schembri JM, Tikellis C, Burrell LM, Angus PW.

Gastroenterology. 2002 Nov;123(5):1667-76. Erratum in: Gastroenterology. 2004 Feb;126(2):634. PMID: 12404241 [PubMed - indexed for MEDLINE]Related articles

Nephrin expression in the post-natal developing kidney in normotensive and hypertensive rats.

Bonnet F, Tikellis C, Kawachi H, Burns WC, Wookey PJ, Cao Z, Cooper ME.

Clin Exp Hypertens. 2002 Jul;24(5):371-81.PMID: 12109777 [PubMed - indexed for MEDLINE]Related articles

Effect of angiotensin II type 1 receptor blockade on experimental hepatic fibrogenesis.

Paizis G, Gilbert RE, Cooper ME, Murthi P, Schembri JM, Wu LL, Rumble JR, Kelly DJ, Tikellis C, Cox A, Smallwood RA, Angus PW.

J Hepatol. 2001 Sep;35(3):376-85.PMID: 11592599 [PubMed - indexed for MEDLINE]Related articles

Amylin as a growth factor during fetal and postnatal development of the rat kidney.

Wookey PJ, Tikellis C, Nobes M, Casley D, Cooper ME, Darby IA.

Kidney Int. 1998 Jan;53(1):25-30.PMID: 9452996 [PubMed - indexed for MEDLINE]Related articlesFree article

Amylin binding in rat renal cortex, stimulation of adenylyl cyclase, and activation of plasma renin.

Wookey PJ, Tikellis C, Du HC, Qin HF, Sexton PM, Cooper ME.

Am J Physiol. 1996 Feb;270(2 Pt 2):F289-94.PMID: 8779889 [PubMed - indexed for MEDLINE]Related articles