PubMed

Cardiac fibroblasts on the fast track--scleraxis: from Achilles' heel to anti-fibrotic therapy.

Kardasinski M, Thum T.

J Mol Cell Cardiol. 2009 Aug;47(2):174-6. Epub 2009 May 20. No abstract available. PMID: 19463829 [PubMed - indexed for MEDLINE]Related articles

Increase of pro-inflammatory cytokine expression in non-demyelinating early cerebral lesions in nervous canine distemper.

Beineke A, Markus S, Borlak J, Thum T, Baumgärtner W.

Viral Immunol. 2008 Dec;21(4):401-10.PMID: 19115929 [PubMed - indexed for MEDLINE]Related articles

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts.

Thum T, Gross C, Fiedler J, Fischer T, Kissler S, Bussen M, Galuppo P, Just S, Rottbauer W, Frantz S, Castoldi M, Soutschek J, Koteliansky V, Rosenwald A, Basson MA, Licht JD, Pena JT, Rouhanifard SH, Muckenthaler MU, Tuschl T, Martin GR, Bauersachs J, Engelhardt S.

Nature. 2008 Dec 18;456(7224):980-4. Epub 2008 Nov 30.PMID: 19043405 [PubMed - indexed for MEDLINE]Related articles

Cardiac dissonance without conductors: how dicer depletion provokes chaos in the heart.

Thum T.

Circulation. 2008 Oct 7;118(15):1524-7. No abstract available. PMID: 18838573 [PubMed - indexed for MEDLINE]Related articlesFree article

No effects of human ghrelin on cardiac function despite profound effects on body composition in a rat model of heart failure.

Akashi YJ, Palus S, Datta R, Halem H, Taylor JE, Thoene-Reineke C, Dong J, Thum T, Culler MD, Anker SD, Springer J.

Int J Cardiol. 2008 Aug 22. [Epub ahead of print]PMID: 18723230 [PubMed - as supplied by publisher]Related articles

Improvement in left ventricular remodeling by the endothelial nitric oxide synthase enhancer AVE9488 after experimental myocardial infarction.

Fraccarollo D, Widder JD, Galuppo P, Thum T, Tsikas D, Hoffmann M, Ruetten H, Ertl G, Bauersachs J.

Circulation. 2008 Aug 19;118(8):818-27. Epub 2008 Aug 4.PMID: 18678774 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of physical exercise on myocardial telomere-regulating proteins, survival pathways, and apoptosis.

Werner C, Hanhoun M, Widmann T, Kazakov A, Semenov A, Pöss J, Bauersachs J, Thum T, Pfreundschuh M, Müller P, Haendeler J, Böhm M, Laufs U.

J Am Coll Cardiol. 2008 Aug 5;52(6):470-82.PMID: 18672169 [PubMed - indexed for MEDLINE]Related articles

Circulating endothelial progenitor cells in patients with Eisenmenger syndrome and idiopathic pulmonary arterial hypertension.

Diller GP, van Eijl S, Okonko DO, Howard LS, Ali O, Thum T, Wort SJ, Bédard E, Gibbs JS, Bauersachs J, Hobbs AJ, Wilkins MR, Gatzoulis MA, Wharton J.

Circulation. 2008 Jun 10;117(23):3020-30. Epub 2008 Jun 2.PMID: 18519847 [PubMed - indexed for MEDLINE]Related articlesFree article

MicroRNAs: novel regulators in cardiac development and disease.

Thum T, Catalucci D, Bauersachs J.

Cardiovasc Res. 2008 Sep 1;79(4):562-70. Epub 2008 May 29. Review.PMID: 18511432 [PubMed - indexed for MEDLINE]Related articlesFree article

LOX-1 receptor blockade abrogates oxLDL-induced oxidative DNA damage and prevents activation of the transcriptional repressor Oct-1 in human coronary arterial endothelium.

Thum T, Borlak J.

J Biol Chem. 2008 Jul 11;283(28):19456-64. Epub 2008 Apr 7.PMID: 18390905 [PubMed - indexed for MEDLINE]Related articlesFree article

The IGF-1 receptor as a therapeutic target to improve endothelial progenitor cell function.

Fleissner F, Thum T.

Mol Med. 2008 May-Jun;14(5-6):235-7. No abstract available. PMID: 18385819 [PubMed - indexed for MEDLINE]Related articlesFree article

Letter by Thum et al regarding article, "Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: restoration by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone".

Thum T, Bauersachs J.

Circulation. 2008 Mar 11;117(10):e185; author reply e186. No abstract available. PMID: 18332272 [PubMed - indexed for MEDLINE]Related articlesFree article

Recent patents on cardiovascular stem cells.

Jakob M, Thum T.

Recent Pat Cardiovasc Drug Discov. 2008 Jan;3(1):59-72. Review.PMID: 18221129 [PubMed - indexed for MEDLINE]Related articles

Effect of intravenous iron sucrose on exercise tolerance in anemic and nonanemic patients with symptomatic chronic heart failure and iron deficiency FERRIC-HF: a randomized, controlled, observer-blinded trial.

Okonko DO, Grzeslo A, Witkowski T, Mandal AK, Slater RM, Roughton M, Foldes G, Thum T, Majda J, Banasiak W, Missouris CG, Poole-Wilson PA, Anker SD, Ponikowski P.

J Am Coll Cardiol. 2008 Jan 15;51(2):103-12.PMID: 18191732 [PubMed - indexed for MEDLINE]Related articles

Nutritional iron deficiency in patients with chronic illnesses.

Thum T, Anker SD.

Lancet. 2007 Dec 8;370(9603):1906. No abstract available. PMID: 18068513 [PubMed - indexed for MEDLINE]Related articles

Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus.

Wenzel P, Daiber A, Oelze M, Brandt M, Closs E, Xu J, Thum T, Bauersachs J, Ertl G, Zou MH, Förstermann U, Münzel T.

Atherosclerosis. 2008 May;198(1):65-76. Epub 2007 Dec 3.PMID: 18061195 [PubMed - indexed for MEDLINE]Related articles

MicroRNAs in the broken heart.

Bauersachs J, Thum T.

Eur J Clin Invest. 2007 Nov;37(11):829-33. Review. No abstract available. PMID: 17973779 [PubMed - indexed for MEDLINE]Related articles

Detection of early signals of hepatotoxicity by gene expression profiling studies with cultures of metabolically competent human hepatocytes.

Thum T, Borlak J.

Arch Toxicol. 2008 Feb;82(2):89-101. Epub 2007 Sep 13.PMID: 17851650 [PubMed - indexed for MEDLINE]Related articles

GC-MS assay for hepatic DDAH activity in diabetic and non-diabetic rats by measuring dimethylamine (DMA) formed from asymmetric dimethylarginine (ADMA): evaluation of the importance of S-nitrosothiols as inhibitors of DDAH activity in vitro and in vivo in humans.

Chobanyan K, Thum T, Suchy MT, Zhu B, Mitschke A, Gutzki FM, Beckmann B, Stichtenoth DO, Tsikas D.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Oct 15;858(1-2):32-41. Epub 2007 Aug 7.PMID: 17825631 [PubMed - indexed for MEDLINE]Related articles

Tilarginine in patients with acute myocardial infarction and cardiogenic shock.

Kielstein JT, Sydow K, Thum T.

JAMA. 2007 Sep 5;298(9):971; author reply 972-3. No abstract available. PMID: 17785641 [PubMed - indexed for MEDLINE]Related articles

Growth hormone treatment improves markers of systemic nitric oxide bioavailability via insulin-like growth factor-I.

Thum T, Fleissner F, Klink I, Tsikas D, Jakob M, Bauersachs J, Stichtenoth DO.

J Clin Endocrinol Metab. 2007 Nov;92(11):4172-9. Epub 2007 Aug 28.PMID: 17726074 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial progenitor cell dysfunction: mechanisms and therapeutic approaches.

Bauersachs J, Thum T.

Eur J Clin Invest. 2007 Aug;37(8):603-6. No abstract available. PMID: 17635570 [PubMed - indexed for MEDLINE]Related articles

MicroRNAs in the human heart: a clue to fetal gene reprogramming in heart failure.

Thum T, Galuppo P, Wolf C, Fiedler J, Kneitz S, van Laake LW, Doevendans PA, Mummery CL, Borlak J, Haverich A, Gross C, Engelhardt S, Ertl G, Bauersachs J.

Circulation. 2007 Jul 17;116(3):258-67. Epub 2007 Jul 2. Erratum in: Circulation. 2007 Jul 17;116(3):e135. PMID: 17606841 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue-specific effects of the nuclear factor kappaB subunit p50 on myocardial ischemia-reperfusion injury.

Frantz S, Tillmanns J, Kuhlencordt PJ, Schmidt I, Adamek A, Dienesch C, Thum T, Gerondakis S, Ertl G, Bauersachs J.

Am J Pathol. 2007 Aug;171(2):507-12. Epub 2007 Jun 7.PMID: 17556593 [PubMed - indexed for MEDLINE]Related articlesFree article

Micrometeorological measurements of methane and carbon dioxide fluxes at a municipal landfill.

Lohila A, Laurila T, Tuovinen JP, Aurela M, Hatakka J, Thum T, Pihlatie M, Rinne J, Vesala T.

Environ Sci Technol. 2007 Apr 15;41(8):2717-22.PMID: 17533829 [PubMed - indexed for MEDLINE]Related articles

Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes.

Thum T, Fraccarollo D, Schultheiss M, Froese S, Galuppo P, Widder JD, Tsikas D, Ertl G, Bauersachs J.

Diabetes. 2007 Mar;56(3):666-74.PMID: 17327434 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential effects of organic nitrates on endothelial progenitor cells are determined by oxidative stress.

Thum T, Fraccarollo D, Thum S, Schultheiss M, Daiber A, Wenzel P, Munzel T, Ertl G, Bauersachs J.

Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):748-54. Epub 2007 Jan 25.PMID: 17255540 [PubMed - indexed for MEDLINE]Related articlesFree article

Age-dependent impairment of endothelial progenitor cells is corrected by growth-hormone-mediated increase of insulin-like growth-factor-1.

Thum T, Hoeber S, Froese S, Klink I, Stichtenoth DO, Galuppo P, Jakob M, Tsikas D, Anker SD, Poole-Wilson PA, Borlak J, Ertl G, Bauersachs J.

Circ Res. 2007 Feb 16;100(3):434-43. Epub 2007 Jan 18.PMID: 17234973 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of xenobiotic metabolizing enzymes in different lung compartments of smokers and nonsmokers.

Thum T, Erpenbeck VJ, Moeller J, Hohlfeld JM, Krug N, Borlak J.

Environ Health Perspect. 2006 Nov;114(11):1655-61.PMID: 17107849 [PubMed - indexed for MEDLINE]Related articlesFree article

Accurate quantification of dimethylamine (DMA) in human urine by gas chromatography-mass spectrometry as pentafluorobenzamide derivative: evaluation of the relationship between DMA and its precursor asymmetric dimethylarginine (ADMA) in health and disease.

Tsikas D, Thum T, Becker T, Pham VV, Chobanyan K, Mitschke A, Beckmann B, Gutzki FM, Bauersachs J, Stichtenoth DO.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 May 15;851(1-2):229-39. Epub 2006 Sep 29.PMID: 17011246 [PubMed - indexed for MEDLINE]Related articles

Sports or statins for atheroprotection? New insight from Kruppel-like factor 2.

Thum T, Bauersachs J.

Cardiovasc Res. 2006 Nov 1;72(2):193-5. Epub 2006 Aug 30. No abstract available. PMID: 17010325 [PubMed - indexed for MEDLINE]Related articlesFree article

Microarray-based gene expression profiling to elucidate cellular responses to nitric oxide--a review from an analytical and biomedical point of view.

Thum T, Bauersachs J.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 May 15;851(1-2):3-11. Epub 2006 Aug 7. Review.PMID: 16891162 [PubMed - indexed for MEDLINE]Related articles

Annual meeting of the American Heart Association. Dallas, Texas, USA, 13-16 November 2005.

von Haehling S, Sandek A, Thum T.

Expert Opin Investig Drugs. 2006 May;15(5):563-9. No abstract available. PMID: 16634694 [PubMed - indexed for MEDLINE]Related articles

Obesity and risk of myocardial infarction: the INTERHEART study.

Thum T, Anker SD.

Lancet. 2006 Apr 1;367(9516):1051-2; author reply 1054. No abstract available. PMID: 16581394 [PubMed - indexed for MEDLINE]Related articles

Bone marrow molecular alterations after myocardial infarction: Impact on endothelial progenitor cells.

Thum T, Fraccarollo D, Galuppo P, Tsikas D, Frantz S, Ertl G, Bauersachs J.

Cardiovasc Res. 2006 Apr 1;70(1):50-60. Epub 2006 Feb 9.PMID: 16480696 [PubMed - indexed for MEDLINE]Related articlesFree article

Spotlight on endothelial progenitor cell inhibitors: short review.

Thum T, Bauersachs J.

Vasc Med. 2005 Jul;10 Suppl 1:S59-64. Review.PMID: 16444870 [PubMed - indexed for MEDLINE]Related articles

Nitrous oxide emissions from a municipal landfill.

Rinne J, Pihlatie M, Lohila A, Thum T, Aurela M, Tuovinen JP, Laurila T, Vesala T.

Environ Sci Technol. 2005 Oct 15;39(20):7790-3.PMID: 16295838 [PubMed - indexed for MEDLINE]Related articles

The dying stem cell hypothesis: immune modulation as a novel mechanism for progenitor cell therapy in cardiac muscle.

Thum T, Bauersachs J, Poole-Wilson PA, Volk HD, Anker SD.

J Am Coll Cardiol. 2005 Nov 15;46(10):1799-802. Epub 2005 Oct 17. Review.PMID: 16286162 [PubMed - indexed for MEDLINE]Related articles

Suppression of endothelial progenitor cells in human coronary artery disease by the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine.

Thum T, Tsikas D, Stein S, Schultheiss M, Eigenthaler M, Anker SD, Poole-Wilson PA, Ertl G, Bauersachs J.

J Am Coll Cardiol. 2005 Nov 1;46(9):1693-701. Epub 2005 Oct 10.PMID: 16256870 [PubMed - indexed for MEDLINE]Related articles

ADMA, endothelial progenitor cells, and cardiovascular risk.

Thum T, Bauersachs J.

Circ Res. 2005 Oct 14;97(8):e84. No abstract available. PMID: 16224069 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial progenitor cells as potential drug targets.

Thum T, Bauersachs J.

Curr Drug Targets Cardiovasc Haematol Disord. 2005 Aug;5(4):277-86. Review.PMID: 16101561 [PubMed - indexed for MEDLINE]Related articles

Cardiac regeneration by progenitor cells--bedside before bench?

Bauersachs J, Thum T, Frantz S, Ertl G.

Eur J Clin Invest. 2005 Jul;35(7):417-20.PMID: 16008541 [PubMed - indexed for MEDLINE]Related articles

Mobilization of bone marrow-derived stem cells after myocardial infarction and left ventricular function: simply effects of optimized drug treatment?

Thum T, Bauersachs J.

Eur Heart J. 2005 Aug;26(16):1685; author reply 1685-6. Epub 2005 Jun 15. No abstract available. PMID: 15958435 [PubMed - indexed for MEDLINE]Related articlesFree article

Temperature dependence of leaf-level CO2 fixation: revising biochemical coefficients through analysis of leaf three-dimensional structure.

Juurola E, Aalto T, Thum T, Vesala T, Hari P.

New Phytol. 2005 Apr;166(1):205-15.PMID: 15760364 [PubMed - indexed for MEDLINE]Related articles

Clostridium difficile toxin A induces expression of the stress-induced early gene product RhoB.

Gerhard R, Tatge H, Genth H, Thum T, Borlak J, Fritz G, Just I.

J Biol Chem. 2005 Jan 14;280(2):1499-505. Epub 2004 Nov 5.PMID: 15531589 [PubMed - indexed for MEDLINE]Related articlesFree article

Endogenous nitric oxide synthesis inhibitor asymmetric dimethyl L-arginine accelerates endothelial cell senescence.

Scalera F, Borlak J, Beckmann B, Martens-Lobenhoffer J, Thum T, Täger M, Bode-Böger SM.

Arterioscler Thromb Vasc Biol. 2004 Oct;24(10):1816-22. Epub 2004 Aug 12.PMID: 15308550 [PubMed - indexed for MEDLINE]Related articlesFree article

Androgen metabolism in thymus of fetal and adult rats.

Borlak J, Schulte I, Thum T.

Drug Metab Dispos. 2004 Jun;32(6):675-9.PMID: 15155560 [PubMed - indexed for MEDLINE]Related articlesFree article

Growth hormone induces eNOS expression and nitric oxide release in a cultured human endothelial cell line.

Thum T, Tsikas D, Frölich JC, Borlak J.

FEBS Lett. 2003 Dec 18;555(3):567-71.PMID: 14675775 [PubMed - indexed for MEDLINE]Related articles

Mechanistic role of cytochrome P450 monooxygenases in oxidized low-density lipoprotein-induced vascular injury: therapy through LOX-1 receptor antagonism?

Thum T, Borlak J.

Circ Res. 2004 Jan 9;94(1):e1-13. Epub 2003 Dec 4.PMID: 14656932 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolism of verapamil: 24 new phase I and phase II metabolites identified in cell cultures of rat hepatocytes by liquid chromatography-tandem mass spectrometry.

Walles M, Thum T, Levsen K, Borlak J.

J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Dec 25;798(2):265-74.PMID: 14643506 [PubMed - indexed for MEDLINE]Related articles