PubMed

Novel Obesity Risk Loci Do Not Determine Distribution of Body Fat Depots: A Whole-body MRI/MRS study.

Haupt A, Thamer C, Heni M, Machicao F, Machann J, Schick F, Stefan N, Fritsche A, Häring HU, Staiger H.

Obesity (Silver Spring). 2009 Nov 12. [Epub ahead of print]PMID: 19910938 [PubMed - as supplied by publisher]Related articles

Correlation of fat distribution in whole body MRI with generally used anthropometric data.

Ludescher B, Machann J, Eschweiler GW, Vanhöfen S, Maenz C, Thamer C, Claussen CD, Schick F.

Invest Radiol. 2009 Nov;44(11):712-9.PMID: 19809346 [PubMed - in process]Related articles

High baseline vitamin C levels do not prevent a positive outcome of a lifestyle intervention.

Thamer C, Machicao F, Stefan N, Fritsche A, Häring HU.

Diabetes Care. 2009 Sep;32(9):e112. No abstract available. PMID: 19717817 [PubMed - indexed for MEDLINE]Related articles

Impact of variation near MC4R on whole-body fat distribution, liver fat, and weight loss.

Haupt A, Thamer C, Heni M, Tschritter O, Machann J, Schick F, Machicao F, Häring HU, Staiger H, Fritsche A.

Obesity (Silver Spring). 2009 Oct;17(10):1942-5. Epub 2009 Jul 30.PMID: 19629057 [PubMed - in process]Related articles

High plasma fetuin-A is associated with increased carotid intima-media thickness in a middle-aged population.

Rittig K, Thamer C, Haupt A, Machann J, Peter A, Balletshofer B, Fritsche A, Haring HU, Stefan N.

Atherosclerosis. 2009 Dec;207(2):341-2. Epub 2009 May 22. No abstract available. PMID: 19615685 [PubMed - in process]Related articles

Individual stearoyl-coa desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo.

Peter A, Weigert C, Staiger H, Machicao F, Schick F, Machann J, Stefan N, Thamer C, Häring HU, Schleicher E.

Diabetes. 2009 Aug;58(8):1757-65. Epub 2009 May 28.PMID: 19478146 [PubMed - indexed for MEDLINE]Related articlesFree article

Intermuscular adipose tissue (IMAT): association with other adipose tissue compartments and insulin sensitivity.

Boettcher M, Machann J, Stefan N, Thamer C, Häring HU, Claussen CD, Fritsche A, Schick F.

J Magn Reson Imaging. 2009 Jun;29(6):1340-5.PMID: 19422021 [PubMed - indexed for MEDLINE]Related articles

RARRES2, encoding the novel adipokine chemerin, is a genetic determinant of disproportionate regional body fat distribution: a comparative magnetic resonance imaging study.

Müssig K, Staiger H, Machicao F, Thamer C, Machann J, Schick F, Claussen CD, Stefan N, Fritsche A, Häring HU.

Metabolism. 2009 Apr;58(4):519-24.PMID: 19303973 [PubMed - indexed for MEDLINE]Related articles

[A rare cause of hypoglycaemia in a patient with type 2 diabetes]

Heni M, Schott S, Horger M, Dudziak K, Thamer C, Häring HU, Fritsche A, Müssig K.

Dtsch Med Wochenschr. 2009;134 Suppl Falldatenbank:F2. Epub 2009 Feb 23. German. PMID: 19235687 [PubMed - indexed for MEDLINE]Related articles

Association of common genetic variation in the FOXO1 gene with beta-cell dysfunction, impaired glucose tolerance, and type 2 diabetes.

Müssig K, Staiger H, Machicao F, Stancáková A, Kuusisto J, Laakso M, Thamer C, Machann J, Schick F, Claussen CD, Stefan N, Fritsche A, Häring HU.

J Clin Endocrinol Metab. 2009 Apr;94(4):1353-60. Epub 2009 Jan 13.PMID: 19141580 [PubMed - indexed for MEDLINE]Related articles

High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease.

Kantartzis K, Thamer C, Peter A, Machann J, Schick F, Schraml C, Königsrainer A, Königsrainer I, Kröber S, Niess A, Fritsche A, Häring HU, Stefan N.

Gut. 2009 Sep;58(9):1281-8. Epub 2008 Dec 11.PMID: 19074179 [PubMed - indexed for MEDLINE]Related articles

Variation in the FTO gene influences food intake but not energy expenditure.

Haupt A, Thamer C, Staiger H, Tschritter O, Kirchhoff K, Machicao F, Häring HU, Stefan N, Fritsche A.

Exp Clin Endocrinol Diabetes. 2009 Apr;117(4):194-7. Epub 2008 Dec 3.PMID: 19053021 [PubMed - indexed for MEDLINE]Related articles

Identification and characterization of metabolically benign obesity in humans.

Stefan N, Kantartzis K, Machann J, Schick F, Thamer C, Rittig K, Balletshofer B, Machicao F, Fritsche A, Häring HU.

Arch Intern Med. 2008 Aug 11;168(15):1609-16.PMID: 18695074 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss.

Haupt A, Thamer C, Machann J, Kirchhoff K, Stefan N, Tschritter O, Machicao F, Schick F, Häring HU, Fritsche A.

Obesity (Silver Spring). 2008 Aug;16(8):1969-72. Epub 2008 May 29.PMID: 18535549 [PubMed - indexed for MEDLINE]Related articles

Liver enzymes and incident diabetes: findings from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study.

Ford ES, Schulze MB, Bergmann MM, Thamer C, Joost HG, Boeing H.

Diabetes Care. 2008 Jun;31(6):1138-43. Epub 2008 Mar 17.PMID: 18346992 [PubMed - indexed for MEDLINE]Related articlesFree article

Variations in PPARD determine the change in body composition during lifestyle intervention: a whole-body magnetic resonance study.

Thamer C, Machann J, Stefan N, Schäfer SA, Machicao F, Staiger H, Laakso M, Böttcher M, Claussen C, Schick F, Fritsche A, Haring HU.

J Clin Endocrinol Metab. 2008 Apr;93(4):1497-500. Epub 2008 Feb 5.PMID: 18252792 [PubMed - indexed for MEDLINE]Related articlesFree article

Symptomatic hypoglycemia during imatinib mesylate in a non-diabetic female patient with gastrointestinal stromal tumor.

Haap M, Gallwitz B, Thamer C, Müssig K, Häring HU, Kanz L, Hartmann JT.

J Endocrinol Invest. 2007 Sep;30(8):688-92.PMID: 17923802 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.

Staiger H, Machicao F, Stefan N, Tschritter O, Thamer C, Kantartzis K, Schäfer SA, Kirchhoff K, Fritsche A, Häring HU.

PLoS One. 2007 Sep 5;2(9):e832.PMID: 17786204 [PubMed - in process]Related articlesFree article

Impact of different fat depots on insulin sensitivity: predominant role of liver fat.

Kirchhoff K, Kantartzis K, Machann J, Schick F, Thamer C, Machicao F, Fritsche A, Häring HU, Stefan N.

J Diabetes Sci Technol. 2007 Sep;1(5):753-9.PMID: 19885144 [PubMed - in process]Free article

Role of AMP-activated protein kinase gamma 3 genetic variability in glucose and lipid metabolism in non-diabetic whites.

Weyrich P, Machicao F, Staiger H, Simon P, Thamer C, Machann J, Schick F, Guirguis A, Fritsche A, Stefan N, Häring HU.

Diabetologia. 2007 Oct;50(10):2097-106. Epub 2007 Aug 14.PMID: 17701023 [PubMed - indexed for MEDLINE]Related articles

Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms.

Schäfer SA, Tschritter O, Machicao F, Thamer C, Stefan N, Gallwitz B, Holst JJ, Dekker JM, 't Hart LM, Nijpels G, van Haeften TW, Häring HU, Fritsche A.

Diabetologia. 2007 Dec;50(12):2443-50. Epub 2007 Jul 28. Erratum in: Diabetologia. 2008 Jan;51(1):208. t' Hart, L M [corrected to 't Hart, L M]. Diabetologia. 2009 Mar;52(3):557. Dosage error in article text. PMID: 17661009 [PubMed - indexed for MEDLINE]Related articlesFree article

Gender specific correlations of adrenal gland size and body fat distribution: a whole body MRI study.

Ludescher B, Najib A, Baar S, Machann J, Thamer C, Schick F, Buchkremer G, Claussen CD, Eschweiler GW.

Horm Metab Res. 2007 Jul;39(7):515-8.PMID: 17611905 [PubMed - indexed for MEDLINE]Related articles

[Gene-environment interactions in the pathogenesis and prevention of type 2 diabetes mellitus]

Fritsche A, Thamer C, Stefan N, Häring HU.

Internist (Berl). 2007 Jul;48(7):669-70, 672, 674-5. Review. German. PMID: 17541530 [PubMed - indexed for MEDLINE]Related articles

The Pro12Ala polymorphism in PPARG2 increases the effectiveness of primary prevention of cardiovascular disease by a lifestyle intervention.

Rittig K, Thamer C, Machicao F, Rietig R, Stefan N, Fritsche A, Haring HU, Balletshofer B.

Diabetologia. 2007 Jun;50(6):1345-7. Epub 2007 Apr 6. No abstract available. PMID: 17415545 [PubMed - indexed for MEDLINE]Related articles

Hypomagnesemia and nephrocalcinosis in a patient with two heterozygous mutations in the CLDN16 gene.

Staiger K, Staiger H, Haas C, Thamer C, Risler T, Machicao F, Häring HU.

J Nephrol. 2007 Jan-Feb;20(1):107-10.PMID: 17347984 [PubMed - indexed for MEDLINE]Related articles

Genetic variations in PPARD and PPARGC1A determine mitochondrial function and change in aerobic physical fitness and insulin sensitivity during lifestyle intervention.

Stefan N, Thamer C, Staiger H, Machicao F, Machann J, Schick F, Venter C, Niess A, Laakso M, Fritsche A, Häring HU.

J Clin Endocrinol Metab. 2007 May;92(5):1827-33. Epub 2007 Feb 27.PMID: 17327385 [PubMed - indexed for MEDLINE]Related articlesFree article

An accurate risk score based on anthropometric, dietary, and lifestyle factors to predict the development of type 2 diabetes.

Schulze MB, Hoffmann K, Boeing H, Linseisen J, Rohrmann S, Möhlig M, Pfeiffer AF, Spranger J, Thamer C, Häring HU, Fritsche A, Joost HG.

Diabetes Care. 2007 Mar;30(3):510-5.PMID: 17327313 [PubMed - indexed for MEDLINE]Related articlesFree article

High visceral fat mass and high liver fat are associated with resistance to lifestyle intervention.

Thamer C, Machann J, Stefan N, Haap M, Schäfer S, Brenner S, Kantartzis K, Claussen C, Schick F, Haring H, Fritsche A.

Obesity (Silver Spring). 2007 Feb;15(2):531-8.PMID: 17299127 [PubMed - indexed for MEDLINE]Related articles

Iodine-induced thyrotoxicosis after ingestion of kelp-containing tea.

Müssig K, Thamer C, Bares R, Lipp HP, Häring HU, Gallwitz B.

J Gen Intern Med. 2006 Jun;21(6):C11-4.PMID: 16808731 [PubMed - indexed for MEDLINE]Related articlesFree article

Beta cell function, insulin resistance and plasma adiponectin concentrations are predictors for the change of postprandial glucose in non-diabetic subjects at risk for type 2 diabetes.

Thamer C, Haap M, Heller E, Joel L, Braun S, Tschritter O, Haring H, Fritsche A.

Horm Metab Res. 2006 Mar;38(3):178-82.PMID: 16673209 [PubMed - indexed for MEDLINE]Related articles

Hepatic lipid accumulation in healthy subjects: a comparative study using spectral fat-selective MRI and volume-localized 1H-MR spectroscopy.

Machann J, Thamer C, Schnoedt B, Stefan N, Haring HU, Claussen CD, Fritsche A, Schick F.

Magn Reson Med. 2006 Apr;55(4):913-7.PMID: 16506186 [PubMed - indexed for MEDLINE]Related articles

New imaging techniques of fat, muscle and liver within the context of determining insulin sensitivity.

Stefan N, Machann J, Schick F, Claussen CD, Thamer C, Fritsche A, Häring HU.

Horm Res. 2005;64 Suppl 3:38-44. Epub 2006 Jan 20. Review.PMID: 16439843 [PubMed - indexed for MEDLINE]Related articles

Association of serum phosphate levels with glucose tolerance, insulin sensitivity and insulin secretion in non-diabetic subjects.

Haap M, Heller E, Thamer C, Tschritter O, Stefan N, Fritsche A.

Eur J Clin Nutr. 2006 Jun;60(6):734-9. Epub 2006 Jan 4.PMID: 16391583 [PubMed - indexed for MEDLINE]Related articles

The association between plasma adiponectin and insulin sensitivity in humans depends on obesity.

Kantartzis K, Fritsche A, Tschritter O, Thamer C, Haap M, Schäfer S, Stumvoll M, Häring HU, Stefan N.

Obes Res. 2005 Oct;13(10):1683-91.PMID: 16286515 [PubMed - indexed for MEDLINE]Related articles

Disseminated epitheloid hemangioendothelioma mimicking symptoms of systemic vasculitis.

Haap M, Kötter I, Horger M, Thamer C, Wehrmann M, Häring HU, Kanz L, Hartmann JT.

Onkologie. 2005 Aug;28(8-9):429-32. Epub 2005 Aug 29.PMID: 16160406 [PubMed - indexed for MEDLINE]Related articles

Age and gender related effects on adipose tissue compartments of subjects with increased risk for type 2 diabetes: a whole body MRI/MRS study.

Machann J, Thamer C, Schnoedt B, Stefan N, Stumvoll M, Haring HU, Claussen CD, Fritsche A, Schick F.

MAGMA. 2005 Jul;18(3):128-37. Epub 2005 Jul 6.PMID: 16001284 [PubMed - indexed for MEDLINE]Related articles

Elevated serum GGT concentrations predict reduced insulin sensitivity and increased intrahepatic lipids.

Thamer C, Tschritter O, Haap M, Shirkavand F, Machann J, Fritsche A, Schick F, Häring H, Stumvoll M.

Horm Metab Res. 2005 Apr;37(4):246-51.PMID: 15952086 [PubMed - indexed for MEDLINE]Related articles

Genetic determinants of insulin action in polycystic ovary syndrome.

Haap M, Machicao F, Stefan N, Thamer C, Tschritter O, Schnuck F, Wallwiener D, Stumvoll M, Häring HU, Fritsche A.

Exp Clin Endocrinol Diabetes. 2005 May;113(5):275-81.PMID: 15926113 [PubMed - indexed for MEDLINE]Related articles

Standardized assessment of whole body adipose tissue topography by MRI.

Machann J, Thamer C, Schnoedt B, Haap M, Haring HU, Claussen CD, Stumvoll M, Fritsche A, Schick F.

J Magn Reson Imaging. 2005 Apr;21(4):455-62.PMID: 15778954 [PubMed - indexed for MEDLINE]Related articles

Reduced adiponectin serum levels in smokers.

Thamer C, Stefan N, Stumvoll M, Häring H, Fritsche A.

Atherosclerosis. 2005 Apr;179(2):421-2. No abstract available. PMID: 15777563 [PubMed - indexed for MEDLINE]Related articles

The -913 G/A glutamine:fructose-6-phosphate aminotransferase gene polymorphism is associated with measures of obesity and intramyocellular lipid content in nondiabetic subjects.

Weigert C, Thamer C, Brodbeck K, Guirguis A, Machicao F, Machann J, Schick F, Stumvoll M, Fritsche A, Häring HU, Schleicher ED.

J Clin Endocrinol Metab. 2005 Mar;90(3):1639-43. Epub 2004 Dec 21.PMID: 15613432 [PubMed - indexed for MEDLINE]Related articlesFree article

Intrahepatic lipids are predicted by visceral adipose tissue mass in healthy subjects.

Thamer C, Machann J, Haap M, Stefan N, Heller E, Schnödt B, Stumvoll M, Claussen C, Fritsche A, Schick F, Häring H.

Diabetes Care. 2004 Nov;27(11):2726-9. No abstract available. PMID: 15505012 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle type dependent increase in intramyocellular lipids during prolonged fasting of human subjects: a proton MRS study.

Wietek BM, Machann J, Mader I, Thamer C, Häring HU, Claussen CD, Stumvoll M, Schick F.

Horm Metab Res. 2004 Sep;36(9):639-44.PMID: 15486816 [PubMed - indexed for MEDLINE]Related articles

Serum adiponectin levels predict the effect of short-term dietary interventions on insulin sensitivity in humans.

Thamer C, Haap M, Bachmann O, Zur Nieden T, Tschritter O, Stefan N, Fritsche A, Jacob S, Stumvoll M, Häring H.

Diabetologia. 2004 Jul;47(7):1303-5. Epub 2004 Jun 25.PMID: 15221137 [PubMed - indexed for MEDLINE]Related articles

The Gly482Ser variant in the peroxisome proliferator-activated receptor gamma coactivator-1 is not associated with diabetes-related traits in non-diabetic German and Dutch populations.

Stumvoll M, Fritsche A, t'Hart LM, Machann J, Thamer C, Tschritter O, Van Haeften TW, Jacob S, Dekker JM, Maassen JA, Machicao F, Schick F, Heine RJ, Häring H.

Exp Clin Endocrinol Diabetes. 2004 May;112(5):253-7.PMID: 15146371 [PubMed - indexed for MEDLINE]Related articles

Relationship between moderate alcohol consumption and adiponectin and insulin sensitivity in a large heterogeneous population.

Thamer C, Haap M, Fritsche A, Haering H, Stumvoll M.

Diabetes Care. 2004 May;27(5):1240. No abstract available. PMID: 15111562 [PubMed - indexed for MEDLINE]Related articlesFree article

[Reduced insulin effect in subclinical fatty liver]

Thamer C, Machann J, Haap M, Bachmann O, Wietek B, Dahl D, Tschritter O, Fritsche A, Jacob S, Schick F, Stumvoll M, Häring H.

Dtsch Med Wochenschr. 2004 Apr 16;129(16):872-5. German. PMID: 15083407 [PubMed - indexed for MEDLINE]Related articles

Multiple symmetric lipomatosis: a paradigm of metabolically innocent obesity?

Haap M, Siewecke C, Thamer C, Machann J, Schick F, Häring HU, Szeimies RM, Stumvoll M.

Diabetes Care. 2004 Mar;27(3):794-5. No abstract available. PMID: 14988304 [PubMed - indexed for MEDLINE]Related articlesFree article

Reduced skeletal muscle oxygen uptake and reduced beta-cell function: two early abnormalities in normal glucose-tolerant offspring of patients with type 2 diabetes.

Thamer C, Stumvoll M, Niess A, Tschritter O, Haap M, Becker R, Shirkavand F, Bachmann O, Rett K, Volk A, Häring H, Fritsche A.

Diabetes Care. 2003 Jul;26(7):2126-32.PMID: 12832324 [PubMed - indexed for MEDLINE]Related articlesFree article

No influence of the PPARgamma2 Pro12Ala genotype on serum adiponectin concentrations in healthy Europeans.

Thamer C, Machicao F, Fritsche A, Stumvoll M, Häring H.

Metabolism. 2003 Jun;52(6):798; author reply 798-9. No abstract available. PMID: 12800109 [PubMed - indexed for MEDLINE]Related articles