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    Results: 30

    1.

    Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner.

    Hansen C, Howlin J, Tengholm A, Dyachok O, Vogel WF, Nairn AC, Greengard P, Andersson T.

    J Biol Chem. 2009 Oct 2;284(40):27533-43. Epub 2009 Aug 3.PMID: 19651774 [PubMed - indexed for MEDLINE]Related articles

    2.

    Spatio-temporal dynamics of phosphatidylinositol-3,4,5-trisphosphate signalling.

    Tengholm A, Idevall-Hagren O.

    Vitam Horm. 2009;80:287-311. Review.PMID: 19251042 [PubMed - indexed for MEDLINE]Related articles

    3.

    Capacitative Ca2+ entry via Orai1 and stromal interacting molecule 1 (STIM1) regulates adenylyl cyclase type 8.

    Martin AC, Willoughby D, Ciruela A, Ayling LJ, Pagano M, Wachten S, Tengholm A, Cooper DM.

    Mol Pharmacol. 2009 Apr;75(4):830-42. Epub 2009 Jan 26. Erratum in: Mol Pharmacol. 2009 May;75(5):1248. PMID: 19171672 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Oscillatory control of insulin secretion.

    Tengholm A, Gylfe E.

    Mol Cell Endocrinol. 2009 Jan 15;297(1-2):58-72. Epub 2008 Jul 26. Review.PMID: 18706473 [PubMed - indexed for MEDLINE]Related articles

    5.

    Glucose-induced cyclic AMP oscillations regulate pulsatile insulin secretion.

    Dyachok O, Idevall-Hagren O, Sågetorp J, Tian G, Wuttke A, Arrieumerlou C, Akusjärvi G, Gylfe E, Tengholm A.

    Cell Metab. 2008 Jul;8(1):26-37.PMID: 18590690 [PubMed - indexed for MEDLINE]Related articles

    6.

    Rapid turnover of phosphatidylinositol-4,5-bisphosphate in insulin-secreting cells mediated by Ca2+ and the ATP-to-ADP ratio.

    Thore S, Wuttke A, Tengholm A.

    Diabetes. 2007 Mar;56(3):818-26.PMID: 17327453 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Cyclic AMP: swing that message!

    Tengholm A.

    Cell Mol Life Sci. 2007 Feb;64(4):382-5. No abstract available. PMID: 17221163 [PubMed - indexed for MEDLINE]Related articles

    8.

    Glucose and insulin synergistically activate phosphatidylinositol 3-kinase to trigger oscillations of phosphatidylinositol 3,4,5-trisphosphate in beta-cells.

    Hagren OI, Tengholm A.

    J Biol Chem. 2006 Dec 22;281(51):39121-7. Epub 2006 Oct 30.PMID: 17074763 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    cAMP oscillations restrict protein kinase A redistribution in insulin-secreting cells.

    Dyachok O, Sågetorp J, Isakov Y, Tengholm A.

    Biochem Soc Trans. 2006 Aug;34(Pt 4):498-501.PMID: 16856843 [PubMed - indexed for MEDLINE]Related articles

    10.

    Involvement of JAK2 and Src kinase tyrosine phosphorylation in human growth hormone-stimulated increases in cytosolic free Ca2+ and insulin secretion.

    Zhang F, Zhang Q, Tengholm A, Sjöholm A.

    Am J Physiol Cell Physiol. 2006 Sep;291(3):C466-75. Epub 2006 Apr 5.PMID: 16597920 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Oscillations of cyclic AMP in hormone-stimulated insulin-secreting beta-cells.

    Dyachok O, Isakov Y, Sågetorp J, Tengholm A.

    Nature. 2006 Jan 19;439(7074):349-52.PMID: 16421574 [PubMed - indexed for MEDLINE]Related articles

    12.

    Feedback activation of phospholipase C via intracellular mobilization and store-operated influx of Ca2+ in insulin-secreting beta-cells.

    Thore S, Dyachok O, Gylfe E, Tengholm A.

    J Cell Sci. 2005 Oct 1;118(Pt 19):4463-71. Epub 2005 Sep 13.PMID: 16159958 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    siRNA produced by recombinant dicer mediates efficient gene silencing in islet cells.

    Hägerkvist R, Mokhtari D, Myers JW, Tengholm A, Welsh N.

    Ann N Y Acad Sci. 2005 Apr;1040:114-22.PMID: 15891014 [PubMed - indexed for MEDLINE]Related articles

    14.

    Oscillations of phospholipase C activity triggered by depolarization and Ca2+ influx in insulin-secreting cells.

    Thore S, Dyachok O, Tengholm A.

    J Biol Chem. 2004 May 7;279(19):19396-400. Epub 2004 Mar 25.PMID: 15044448 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Single cell imaging of PI3K activity and glucose transporter insertion into the plasma membrane by dual color evanescent wave microscopy.

    Tengholm A, Teruel MN, Meyer T.

    Sci STKE. 2003 Feb 11;2003(169):PL4.PMID: 12582202 [PubMed - indexed for MEDLINE]Related articles

    16.

    A PI3-kinase signaling code for insulin-triggered insertion of glucose transporters into the plasma membrane.

    Tengholm A, Meyer T.

    Curr Biol. 2002 Oct 29;12(21):1871-6.PMID: 12419189 [PubMed - indexed for MEDLINE]Related articles

    17.

    The endoplasmic reticulum is a glucose-modulated high-affinity sink for Ca2+ in mouse pancreatic beta-cells.

    Tengholm A, Hellman B, Gylfe E.

    J Physiol. 2001 Feb 1;530(Pt 3):533-40.PMID: 11158282 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Signaling underlying pulsatile insulin secretion.

    Gylfe E, Ahmed M, Bergsten P, Dansk H, Dyachok O, Eberhardson M, Grapengiesser E, Hellman B, Lin JM, Sundsten T, Tengholm A, Vieira E, Westerlund J.

    Ups J Med Sci. 2000;105(2):35-51. Review. No abstract available. PMID: 11095104 [PubMed - indexed for MEDLINE]Related articles

    19.

    Mobilization of Ca2+ stores in individual pancreatic beta-cells permeabilized or not with digitonin or alpha-toxin.

    Tengholm A, Hellman B, Gylfe E.

    Cell Calcium. 2000 Jan;27(1):43-51.PMID: 10726210 [PubMed - indexed for MEDLINE]Related articles

    20.

    Glucose regulation of free Ca(2+) in the endoplasmic reticulum of mouse pancreatic beta cells.

    Tengholm A, Hellman B, Gylfe E.

    J Biol Chem. 1999 Dec 24;274(52):36883-90.PMID: 10601240 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    Cell interactions with collagen matrices in vivo and in vitro depend on phosphatidylinositol 3-kinase and free cytoplasmic calcium.

    Ahlén K, Berg A, Stiger F, Tengholm A, Siegbahn A, Gylfe E, Reed RK, Rubin K.

    Cell Adhes Commun. 1998 Sep;5(6):461-73.PMID: 9791727 [PubMed - indexed for MEDLINE]Related articles

    22.

    In situ characterization of nonmitochondrial Ca2+ stores in individual pancreatic beta-cells.

    Tengholm A, Hagman C, Gylfe E, Hellman B.

    Diabetes. 1998 Aug;47(8):1224-30.PMID: 9703321 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    Origin of slow and fast oscillations of Ca2+ in mouse pancreatic islets.

    Liu YJ, Tengholm A, Grapengiesser E, Hellman B, Gylfe E.

    J Physiol. 1998 Apr 15;508 ( Pt 2):471-81.PMID: 9508810 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    Generation of glucose-dependent slow oscillations of cytoplasmic Ca2+ in individual pancreatic beta cells.

    Gylfe E, Grapengiesser E, Liu YJ, Dryselius S, Tengholm A, Eberhardson M.

    Diabetes Metab. 1998 Feb;24(1):25-9. Review.PMID: 9534005 [PubMed - indexed for MEDLINE]Related articlesFree article

    25.

    Oscillatory signaling and insulin release in human pancreatic beta-cells exposed to strontium.

    Hellman B, Gylfe E, Bergsten P, Grapengiesser E, Berts A, Liu YJ, Tengholm A, Westerlund J.

    Endocrinology. 1997 Aug;138(8):3161-5.PMID: 9231763 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    The role of plasma membrane K+ and Ca2+ permeabilities for glucose induction of slow Ca2+ oscillations in pancreatic beta-cells.

    Eberhardson M, Tengholm A, Grapengiesser E.

    Biochim Biophys Acta. 1996 Aug 14;1283(1):67-72.PMID: 8765096 [PubMed - indexed for MEDLINE]Related articles

    27.

    Glucose induces oscillatory Ca2+ signalling and insulin release in human pancreatic beta cells.

    Hellman B, Gylfe E, Bergsten P, Grapengiesser E, Lund PE, Berts A, Tengholm A, Pipeleers DG, Ling Z.

    Diabetologia. 1994 Sep;37 Suppl 2:S11-20.PMID: 7821725 [PubMed - indexed for MEDLINE]Related articles

    28.

    Synchronous oscillations of cytoplasmic Ca2+ and insulin release in glucose-stimulated pancreatic islets.

    Bergsten P, Grapengiesser E, Gylfe E, Tengholm A, Hellman B.

    J Biol Chem. 1994 Mar 25;269(12):8749-53.PMID: 8132606 [PubMed - indexed for MEDLINE]Related articlesFree article

    29.

    The role of Ca2+ in the release of pancreatic islet hormones.

    Hellman B, Gylfe E, Bergsten P, Grapengiesser E, Lund PE, Berts A, Dryselius S, Tengholm A, Liu YJ, Eberhardson M, et al.

    Diabete Metab. 1994 Mar-Apr;20(2):123-31.PMID: 7805949 [PubMed - indexed for MEDLINE]Related articles

    30.

    Glycine transformation of Ca2+ oscillations into a sustained increase parallels potentiation of insulin release.

    Tengholm A, McClenaghan N, Grapengiesser E, Gylfe E, Hellman B.

    Biochim Biophys Acta. 1992 Nov 17;1137(3):243-7.PMID: 1445926 [PubMed - indexed for MEDLINE]Related articles

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