PubMed

Reduced conditioned fear response in mice that lack Dlx1 and show subtype-specific loss of interneurons.

Mao R, Page DT, Merzlyak I, Kim C, Tecott LH, Janak PH, Rubenstein JL, Sur M.

J Neurodev Disord. 2009 Sep;1(3):224-236. Epub 2009 Jul 11.PMID: 19816534 [PubMed]Related articlesFree article

A serotonin-dependent mechanism explains the leptin regulation of bone mass, appetite, and energy expenditure.

Yadav VK, Oury F, Suda N, Liu ZW, Gao XB, Confavreux C, Klemenhagen KC, Tanaka KF, Gingrich JA, Guo XE, Tecott LH, Mann JJ, Hen R, Horvath TL, Karsenty G.

Cell. 2009 Sep 4;138(5):976-89.PMID: 19737523 [PubMed - indexed for MEDLINE]Related articles

Chronic citalopram administration causes a sustained suppression of serotonin synthesis in the mouse forebrain.

Honig G, Jongsma ME, van der Hart MC, Tecott LH.

PLoS One. 2009 Aug 27;4(8):e6797.PMID: 19710918 [PubMed - in process]Related articlesFree article

Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function.

Abdallah L, Bonasera SJ, Hopf FW, O'Dell L, Giorgetti M, Jongsma M, Carra S, Pierucci M, Di Giovanni G, Esposito E, Parsons LH, Bonci A, Tecott LH.

J Neurosci. 2009 Jun 24;29(25):8156-65.PMID: 19553455 [PubMed - indexed for MEDLINE]Related articles

A robust automated system elucidates mouse home cage behavioral structure.

Goulding EH, Schenk AK, Juneja P, MacKay AW, Wade JM, Tecott LH.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20575-82. Epub 2008 Dec 23.PMID: 19106295 [PubMed - indexed for MEDLINE]Related articlesFree article

Deletion of Mecp2 in Sim1-expressing neurons reveals a critical role for MeCP2 in feeding behavior, aggression, and the response to stress.

Fyffe SL, Neul JL, Samaco RC, Chao HT, Ben-Shachar S, Moretti P, McGill BE, Goulding EH, Sullivan E, Tecott LH, Zoghbi HY.

Neuron. 2008 Sep 25;59(6):947-58.PMID: 18817733 [PubMed - indexed for MEDLINE]Related articlesFree article

It is time to take a stand for medical research and against terrorism targeting medical scientists.

Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, Berman KF, Blair J, Braff DL, Brown ES, Calabrese JR, Carlezon WA Jr, Cook EH Jr, Davidson RJ, Davis M, Desimone R, Drevets WC, Duman RS, Essock SM, Faraone SV, Freedman R, Friston KJ, Gelernter J, Geller B, Gill M, Gould E, Grace AA, Grillon C, Gueorguieva R, Hariri AR, Innis RB, Jones EG, Kleinman JE, Koob GF, Krystal AD, Leibenluft E, Levinson DF, Levitt PR, Lewis DA, Liberzon I, Lipska BK, Marder SR, Markou A, Mason GF, McDougle CJ, McEwen BS, McMahon FJ, Meaney MJ, Meltzer HY, Merikangas KR, Meyer-Lindenberg A, Mirnics K, Monteggia LM, Neumeister A, O'Brien CP, Owen MJ, Pine DS, Rapoport JL, Rauch SL, Robbins TW, Rosenbaum JF, Rosenberg DR, Ross CA, Rush AJ, Sackeim HA, Sanacora G, Schatzberg AF, Shaham Y, Siever LJ, Sunderland T, Tecott LH, Thase ME, Todd RD, Weissman MM, Yehuda R, Yoshikawa T, Young EA, McCandless R.

Biol Psychiatry. 2008 Apr 15;63(8):725-7. No abstract available. Erratum in: Biol Psychiatry. 2008 May 15;63(10):1001. PMID: 18371494 [PubMed - indexed for MEDLINE]Related articles

A novel method for automatic quantification of psychostimulant-evoked route-tracing stereotypy: application to Mus musculus.

Bonasera SJ, Schenk AK, Luxenberg EJ, Tecott LH.

Psychopharmacology (Berl). 2008 Mar;196(4):591-602. Epub 2007 Dec 21.PMID: 18097652 [PubMed - indexed for MEDLINE]Related articlesFree article

Synergistic impairment of glucose homeostasis in ob/ob mice lacking functional serotonin 2C receptors.

Wade JM, Juneja P, MacKay AW, Graham J, Havel PJ, Tecott LH, Goulding EH.

Endocrinology. 2008 Mar;149(3):955-61. Epub 2007 Nov 26.PMID: 18039786 [PubMed - indexed for MEDLINE]Related articlesFree article

Serotonin and the orchestration of energy balance.

Tecott LH.

Cell Metab. 2007 Nov;6(5):352-61. Review.PMID: 17983581 [PubMed - indexed for MEDLINE]Related articles

Serotonin activates the hypothalamic-pituitary-adrenal axis via serotonin 2C receptor stimulation.

Heisler LK, Pronchuk N, Nonogaki K, Zhou L, Raber J, Tung L, Yeo GS, O'Rahilly S, Colmers WF, Elmquist JK, Tecott LH.

J Neurosci. 2007 Jun 27;27(26):6956-64.PMID: 17596444 [PubMed - indexed for MEDLINE]Related articlesFree article

Serotonin 5-HT(2C) receptors regulate anxiety-like behavior.

Heisler LK, Zhou L, Bajwa P, Hsu J, Tecott LH.

Genes Brain Behav. 2007 Jul;6(5):491-6. Epub 2007 Apr 19.PMID: 17451451 [PubMed - indexed for MEDLINE]Related articles

Essential function of HIPK2 in TGFbeta-dependent survival of midbrain dopamine neurons.

Zhang J, Pho V, Bonasera SJ, Holtzman J, Tang AT, Hellmuth J, Tang S, Janak PH, Tecott LH, Huang EJ.

Nat Neurosci. 2007 Jan;10(1):77-86. Epub 2006 Dec 10.PMID: 17159989 [PubMed - indexed for MEDLINE]Related articles

Alpha1-adrenergic receptors prevent a maladaptive cardiac response to pressure overload.

O'Connell TD, Swigart PM, Rodrigo MC, Ishizaka S, Joho S, Turnbull L, Tecott LH, Baker AJ, Foster E, Grossman W, Simpson PC.

J Clin Invest. 2006 Apr;116(4):1005-15.PMID: 16585965 [PubMed - indexed for MEDLINE]Related articlesFree article

A null mutation of the serotonin 6 receptor alters acute responses to ethanol.

Bonasera SJ, Chu HM, Brennan TJ, Tecott LH.

Neuropsychopharmacology. 2006 Aug;31(8):1801-13. Epub 2006 Feb 1.PMID: 16452990 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular determinants in the second intracellular loop of the 5-hydroxytryptamine-1A receptor for G-protein coupling.

Kushwaha N, Harwood SC, Wilson AM, Berger M, Tecott LH, Roth BL, Albert PR.

Mol Pharmacol. 2006 May;69(5):1518-26. Epub 2006 Jan 12.PMID: 16410407 [PubMed - indexed for MEDLINE]Related articlesFree article

Social circuits: peptidergic regulation of mammalian social behavior.

Storm EE, Tecott LH.

Neuron. 2005 Aug 18;47(4):483-6. Review.PMID: 16102531 [PubMed - indexed for MEDLINE]Related articles

Dysregulation of striatal dopamine signaling by amphetamine inhibits feeding by hungry mice.

Cannon CM, Abdallah L, Tecott LH, During MJ, Palmiter RD.

Neuron. 2004 Oct 28;44(3):509-20.PMID: 15504330 [PubMed - indexed for MEDLINE]Related articles

Inactivation of 5-HT(2C) receptors potentiates consequences of serotonin reuptake blockade.

Cremers TI, Giorgetti M, Bosker FJ, Hogg S, Arnt J, Mørk A, Honig G, Bøgesø KP, Westerink BH, den Boer H, Wikstrom HV, Tecott LH.

Neuropsychopharmacology. 2004 Oct;29(10):1782-9.PMID: 15138437 [PubMed - indexed for MEDLINE]Related articlesFree article

Neurobehavioral assessment in the information age.

Tecott LH, Nestler EJ.

Nat Neurosci. 2004 May;7(5):462-6. Review.PMID: 15114359 [PubMed - indexed for MEDLINE]Related articles

Contributions of 5-HT(2C) receptors to multiple actions of central serotonin systems.

Giorgetti M, Tecott LH.

Eur J Pharmacol. 2004 Mar 19;488(1-3):1-9. Review.PMID: 15044029 [PubMed - indexed for MEDLINE]Related articles

Mouse genetic approaches to feeding regulation: serotonin 5-HT2C receptor mutant mice.

Tecott LH, Abdallah L.

CNS Spectr. 2003 Aug;8(8):584-8. Review.PMID: 12907921 [PubMed - indexed for MEDLINE]Related articles

Central serotonin and melanocortin pathways regulating energy homeostasis.

Heisler LK, Cowley MA, Kishi T, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro JB, Zigman JM, Cone RD, Elmquist JK.

Ann N Y Acad Sci. 2003 Jun;994:169-74. Review.PMID: 12851313 [PubMed - indexed for MEDLINE]Related articles

Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor.

Xu B, Goulding EH, Zang K, Cepoi D, Cone RD, Jones KR, Tecott LH, Reichardt LF.

Nat Neurosci. 2003 Jul;6(7):736-42.PMID: 12796784 [PubMed - indexed for MEDLINE]Related articlesFree article

The genes and brains of mice and men.

Tecott LH.

Am J Psychiatry. 2003 Apr;160(4):646-56. Review.PMID: 12668350 [PubMed - indexed for MEDLINE]Related articlesFree article

Hyperactivity and reduced energy cost of physical activity in serotonin 5-HT(2C) receptor mutant mice.

Nonogaki K, Abdallah L, Goulding EH, Bonasera SJ, Tecott LH.

Diabetes. 2003 Feb;52(2):315-20.PMID: 12540602 [PubMed - indexed for MEDLINE]Related articlesFree article

Sleep and sleep homeostasis in mice lacking the 5-HT2c receptor.

Frank MG, Stryker MP, Tecott LH.

Neuropsychopharmacology. 2002 Nov;27(5):869-73.PMID: 12431861 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced locomotor, reinforcing, and neurochemical effects of cocaine in serotonin 5-hydroxytryptamine 2C receptor mutant mice.

Rocha BA, Goulding EH, O'Dell LE, Mead AN, Coufal NG, Parsons LH, Tecott LH.

J Neurosci. 2002 Nov 15;22(22):10039-45.PMID: 12427861 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered gene expressions involved in energy expenditure in 5-HT(2C) receptor mutant mice.

Nonogaki K, Memon RA, Grunfeld C, Feingold KR, Tecott LH.

Biochem Biophys Res Commun. 2002 Jul 12;295(2):249-54.PMID: 12150939 [PubMed - indexed for MEDLINE]Related articles

Activation of central melanocortin pathways by fenfluramine.

Heisler LK, Cowley MA, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro JB, Marcus JN, Holstege H, Lee CE, Cone RD, Elmquist JK.

Science. 2002 Jul 26;297(5581):609-11.PMID: 12142539 [PubMed - indexed for MEDLINE]Related articlesFree article

Serotonin 5- HT (2C) receptor knockout mice: autoradiographic analysis of multiple serotonin receptors.

López-Giménez JF, Tecott LH, Palacios JM, Mengod G, Vilaró MT.

J Neurosci Res. 2002 Jan 1;67(1):69-85.PMID: 11754082 [PubMed - indexed for MEDLINE]Related articles

Mouse molecular genetic technologies: promise for psychiatric research.

Tecott LH, Wehner JM.

Arch Gen Psychiatry. 2001 Nov;58(11):995-1004.PMID: 11695945 [PubMed - indexed for MEDLINE]Related articles

Summary of a National Institute of Mental Health workshop: developing animal models of anxiety disorders.

Shekhar A, McCann UD, Meaney MJ, Blanchard DC, Davis M, Frey KA, Liberzon I, Overall KL, Shear MK, Tecott LH, Winsky L.

Psychopharmacology (Berl). 2001 Oct;157(4):327-39.PMID: 11605091 [PubMed - indexed for MEDLINE]Related articles

5-HT(1A) receptor mutant mice exhibit enhanced tonic, stress-induced and fluoxetine-induced serotonergic neurotransmission.

Parsons LH, Kerr TM, Tecott LH.

J Neurochem. 2001 Apr;77(2):607-17.PMID: 11299323 [PubMed - indexed for MEDLINE]Related articles

Knockout Corner: Neurobehavioural consequences of a serotonin 5-HT(2C) receptor gene mutation.

Heisler LK, Tecott LH.

Int J Neuropsychopharmacol. 1999 Mar;2(1):67-69.PMID: 11281972 [PubMed - as supplied by publisher]Related articles

Mouse models of serotonin receptor function: toward a genetic dissection of serotonin systems.

Bonasera SJ, Tecott LH.

Pharmacol Ther. 2000 Nov;88(2):133-42. Review.PMID: 11150593 [PubMed - indexed for MEDLINE]Related articles

Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in the liver of obese diabetic mice.

Memon RA, Tecott LH, Nonogaki K, Beigneux A, Moser AH, Grunfeld C, Feingold KR.

Endocrinology. 2000 Nov;141(11):4021-31.PMID: 11089532 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo electrophysiological examination of 5-HT2 responses in 5-HT2C receptor mutant mice.

Rueter LE, Tecott LH, Blier P.

Naunyn Schmiedebergs Arch Pharmacol. 2000 May;361(5):484-91.PMID: 10832601 [PubMed - indexed for MEDLINE]Related articles

Designer genes and anti-anxiety drugs.

Tecott LH.

Nat Neurosci. 2000 Jun;3(6):529-30. No abstract available. PMID: 10816304 [PubMed - indexed for MEDLINE]Related articles

A paradoxical locomotor response in serotonin 5-HT(2C) receptor mutant mice.

Heisler LK, Tecott LH.

J Neurosci. 2000 Apr 15;20(8):RC71.PMID: 10751458 [PubMed - indexed for MEDLINE]Related articles

Reduced satiating effect of d-fenfluramine in serotonin 5-HT(2C) receptor mutant mice.

Vickers SP, Clifton PG, Dourish CT, Tecott LH.

Psychopharmacology (Berl). 1999 Apr;143(3):309-14.PMID: 10353435 [PubMed - indexed for MEDLINE]Related articles

Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase.

Kash SF, Tecott LH, Hodge C, Baekkeskov S.

Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1698-703.PMID: 9990087 [PubMed - indexed for MEDLINE]Related articlesFree article

Epilepsy and obesity in serotonin 5-HT2C receptor mutant mice.

Heisler LK, Chu HM, Tecott LH.

Ann N Y Acad Sci. 1998 Dec 15;861:74-8. Review.PMID: 9928241 [PubMed - indexed for MEDLINE]Related articles

Global increases in seizure susceptibility in mice lacking 5-HT2C receptors: a behavioral analysis.

Applegate CD, Tecott LH.

Exp Neurol. 1998 Dec;154(2):522-30.PMID: 9878187 [PubMed - indexed for MEDLINE]Related articles

Y do we drink?

Tecott LH, Heberlein U.

Cell. 1998 Dec 11;95(6):733-5. Review. No abstract available. PMID: 9865690 [PubMed - indexed for MEDLINE]Related articles

Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice.

Heisler LK, Chu HM, Brennan TJ, Danao JA, Bajwa P, Parsons LH, Tecott LH.

Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):15049-54.PMID: 9844013 [PubMed - indexed for MEDLINE]Related articlesFree article

Perturbed dentate gyrus function in serotonin 5-HT2C receptor mutant mice.

Tecott LH, Logue SF, Wehner JM, Kauer JA.

Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):15026-31.PMID: 9844009 [PubMed - indexed for MEDLINE]Related articlesFree article

Leptin-independent hyperphagia and type 2 diabetes in mice with a mutated serotonin 5-HT2C receptor gene.

Nonogaki K, Strack AM, Dallman MF, Tecott LH.

Nat Med. 1998 Oct;4(10):1152-6.PMID: 9771748 [PubMed - indexed for MEDLINE]Related articles

Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase.

Kash SF, Johnson RS, Tecott LH, Noebels JL, Mayfield RD, Hanahan D, Baekkeskov S.

Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):14060-5.PMID: 9391152 [PubMed - indexed for MEDLINE]Related articlesFree article

Sound-induced seizures in serotonin 5-HT2c receptor mutant mice.

Brennan TJ, Seeley WW, Kilgard M, Schreiner CE, Tecott LH.

Nat Genet. 1997 Aug;16(4):387-90.PMID: 9241279 [PubMed - indexed for MEDLINE]Related articles