PubMed

Substance P promotes expansion of human mesenteric preadipocytes through proliferative and antiapoptotic pathways.

Gross K, Karagiannides I, Thomou T, Koon HW, Bowe C, Kim H, Giorgadze N, Tchkonia T, Pirtskhalava T, Kirkland JL, Pothoulakis C.

Am J Physiol Gastrointest Liver Physiol. 2009 May;296(5):G1012-9. Epub 2009 Mar 12.PMID: 19282377 [PubMed - indexed for MEDLINE]Related articles

Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes.

Gupta V, Bhasin S, Guo W, Singh R, Miki R, Chauhan P, Choong K, Tchkonia T, Lebrasseur NK, Flanagan JN, Hamilton JA, Viereck JC, Narula NS, Kirkland JL, Jasuja R.

Mol Cell Endocrinol. 2008 Dec 16;296(1-2):32-40. Epub 2008 Aug 28.PMID: 18801408 [PubMed - indexed for MEDLINE]Related articles

Inducible Toll-like receptor and NF-kappaB regulatory pathway expression in human adipose tissue.

Vitseva OI, Tanriverdi K, Tchkonia TT, Kirkland JL, McDonnell ME, Apovian CM, Freedman J, Gokce N.

Obesity (Silver Spring). 2008 May;16(5):932-7. Epub 2008 Feb 21.PMID: 18292749 [PubMed - indexed for MEDLINE]Related articles

Increased TNFalpha and CCAAT/enhancer-binding protein homologous protein with aging predispose preadipocytes to resist adipogenesis.

Tchkonia T, Pirtskhalava T, Thomou T, Cartwright MJ, Wise B, Karagiannides I, Shpilman A, Lash TL, Becherer JD, Kirkland JL.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1810-9. Epub 2007 Oct 2.PMID: 17911345 [PubMed - indexed for MEDLINE]Related articlesFree article

Aging in adipocytes: potential impact of inherent, depot-specific mechanisms.

Cartwright MJ, Tchkonia T, Kirkland JL.

Exp Gerontol. 2007 Jun;42(6):463-71. Epub 2007 Mar 25. Review.PMID: 17507194 [PubMed - indexed for MEDLINE]Related articlesFree article

Aging results in paradoxical susceptibility of fat cell progenitors to lipotoxicity.

Guo W, Pirtskhalava T, Tchkonia T, Xie W, Thomou T, Han J, Wang T, Wong S, Cartwright A, Hegardt FG, Corkey BE, Kirkland JL.

Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1041-51. Epub 2006 Dec 5.PMID: 17148751 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification of depot-specific human fat cell progenitors through distinct expression profiles and developmental gene patterns.

Tchkonia T, Lenburg M, Thomou T, Giorgadze N, Frampton G, Pirtskhalava T, Cartwright A, Cartwright M, Flanagan J, Karagiannides I, Gerry N, Forse RA, Tchoukalova Y, Jensen MD, Pothoulakis C, Kirkland JL.

Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E298-307. Epub 2006 Sep 19.PMID: 16985259 [PubMed - indexed for MEDLINE]Related articlesFree article

Fat depot-specific characteristics are retained in strains derived from single human preadipocytes.

Tchkonia T, Giorgadze N, Pirtskhalava T, Thomou T, DePonte M, Koo A, Forse RA, Chinnappan D, Martin-Ruiz C, von Zglinicki T, Kirkland JL.

Diabetes. 2006 Sep;55(9):2571-8.PMID: 16936206 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased CUG triplet repeat-binding protein-1 predisposes to impaired adipogenesis with aging.

Karagiannides I, Thomou T, Tchkonia T, Pirtskhalava T, Kypreos KE, Cartwright A, Dalagiorgou G, Lash TL, Farmer SR, Timchenko NA, Kirkland JL.

J Biol Chem. 2006 Aug 11;281(32):23025-33. Epub 2006 Jun 5.PMID: 16754681 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of colitis causes inflammatory responses in fat depots: evidence for substance P pathways in human mesenteric preadipocytes.

Karagiannides I, Kokkotou E, Tansky M, Tchkonia T, Giorgadze N, O'Brien M, Leeman SE, Kirkland JL, Pothoulakis C.

Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5207-12. Epub 2006 Mar 20.PMID: 16549770 [PubMed - indexed for MEDLINE]Related articlesFree article

Abundance of two human preadipocyte subtypes with distinct capacities for replication, adipogenesis, and apoptosis varies among fat depots.

Tchkonia T, Tchoukalova YD, Giorgadze N, Pirtskhalava T, Karagiannides I, Forse RA, Koo A, Stevenson M, Chinnappan D, Cartwright A, Jensen MD, Kirkland JL.

Am J Physiol Endocrinol Metab. 2005 Jan;288(1):E267-77. Epub 2004 Sep 21.PMID: 15383371 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipogenesis and aging: does aging make fat go MAD?

Kirkland JL, Tchkonia T, Pirtskhalava T, Han J, Karagiannides I.

Exp Gerontol. 2002 Jun;37(6):757-67. Review.PMID: 12175476 [PubMed - indexed for MEDLINE]Related articles

Fat depot origin affects adipogenesis in primary cultured and cloned human preadipocytes.

Tchkonia T, Giorgadze N, Pirtskhalava T, Tchoukalova Y, Karagiannides I, Forse RA, DePonte M, Stevenson M, Guo W, Han J, Waloga G, Lash TL, Jensen MD, Kirkland JL.

Am J Physiol Regul Integr Comp Physiol. 2002 May;282(5):R1286-96.PMID: 11959668 [PubMed - indexed for MEDLINE]Related articles

Altered expression of C/EBP family members results in decreased adipogenesis with aging.

Karagiannides I, Tchkonia T, Dobson DE, Steppan CM, Cummins P, Chan G, Salvatori K, Hadzopoulou-Cladaras M, Kirkland JL.

Am J Physiol Regul Integr Comp Physiol. 2001 Jun;280(6):R1772-80.PMID: 11353682 [PubMed - indexed for MEDLINE]Related articles

Fat depot origin affects fatty acid handling in cultured rat and human preadipocytes.

Caserta F, Tchkonia T, Civelek VN, Prentki M, Brown NF, McGarry JD, Forse RA, Corkey BE, Hamilton JA, Kirkland JL.

Am J Physiol Endocrinol Metab. 2001 Feb;280(2):E238-47.PMID: 11158926 [PubMed - indexed for MEDLINE]Related articlesFree article

Preferential extrachromosomal localization of exogenous DNA in transgenic silkworm Bombyx mori L.

Nikolaev AI, Tchkonia TT, Kafiani-Eristavi CA, Tarantul VZ.

Mol Gen Genet. 1993 Jan;236(2-3):326-30.PMID: 8382341 [PubMed - indexed for MEDLINE]Related articles