Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1994 1
1997 1
2004 1
2005 2
2007 1
2008 2
2009 4
2010 2
2011 2
2012 2
2013 4
2014 3
2015 4
2016 3
2017 7
2018 3
2019 7
2020 5
2021 4
2022 10
2023 8
2024 10

Text availability

Article attribute

Article type

Publication date

Search Results

79 results

Results by year

Filters applied: . Clear all
Page 1
Novel TBXAS1 variants in two Indian children with Ghosal hematodiaphyseal dysplasia: A concise report.
Sudhakar M, Sharma M, Kandasamy S, Gummadi A, Rawat A, Vignesh P. Sudhakar M, et al. Eur J Med Genet. 2022 May;65(5):104498. doi: 10.1016/j.ejmg.2022.104498. Epub 2022 Apr 6. Eur J Med Genet. 2022. PMID: 35395429
We describe 2 such cases with clinical and radiological evidence of GHDD. Molecular analysis revealed novel variants in TBXAS1 gene in both of them. Suspicion and confirmation of this entity is crucial in cases of refractory anemia with bony deformities, as the clinical ma …
We describe 2 such cases with clinical and radiological evidence of GHDD. Molecular analysis revealed novel variants in TBXAS1 gene i …
TBXAS1 Gene Polymorphism Is Associated with the Risk of Ischemic Stroke of Metabolic Syndrome in a Chinese Han Population.
Peng J, Lu F, Zhong M, Zhao Y, Wang Z, Zhang W. Peng J, et al. Dis Markers. 2022 Jul 25;2022:9717510. doi: 10.1155/2022/9717510. eCollection 2022. Dis Markers. 2022. PMID: 35923246 Free PMC article.
OBJECTIVE: To investigate the association between thromboxane A synthase 1 (TBXAS1) gene polymorphism and metabolic syndrome (MS) and explore whether gene polymorphism could act as biomarkers in MS and its components or whether it could play a role in MS-related damage. .. …
OBJECTIVE: To investigate the association between thromboxane A synthase 1 (TBXAS1) gene polymorphism and metabolic syndrome (MS) and …
Downregulation of TBXAS1 in an iron-induced malignant mesothelioma model.
Minami D, Takigawa N, Kato Y, Kudo K, Isozaki H, Hashida S, Harada D, Ochi N, Fujii M, Kubo T, Ohashi K, Sato A, Tanaka T, Hotta K, Tabata M, Toyooka S, Tanimoto M, Kiura K. Minami D, et al. Cancer Sci. 2015 Oct;106(10):1296-302. doi: 10.1111/cas.12752. Epub 2015 Sep 19. Cancer Sci. 2015. PMID: 26211743 Free PMC article.
In conclusion, TBXAS1 gene expression was downregulated in rats with iron-induced mesothelioma. The relationship between iron overload and TBXAS1 downregulation should be pursued further....
In conclusion, TBXAS1 gene expression was downregulated in rats with iron-induced mesothelioma. The relationship between iron overloa …
Identification of a six-gene prognostic signature for bladder cancer associated macrophage.
Jiang Y, Qu X, Zhang M, Zhang L, Yang T, Ma M, Jing M, Zhang N, Song R, Zhang Y, Yang Z, Zhang Y, Pu Y, Fan J. Jiang Y, et al. Front Immunol. 2022 Oct 6;13:930352. doi: 10.3389/fimmu.2022.930352. eCollection 2022. Front Immunol. 2022. PMID: 36275756 Free PMC article.
Simultaneously, we used the Least Absolute Shrinkage and Selection Operator (LASSO) and univariate and multivariate Cox regressions to establish a TMA-related prognostic model containing six key genes: TBXAS1, GYPC, HPGDS, GAB3, ADORA3, and FOLR2. Subsequently, single-cell …
Simultaneously, we used the Least Absolute Shrinkage and Selection Operator (LASSO) and univariate and multivariate Cox regressions to estab …
Novel compound heterozygous variants of TBXAS1 presenting with Ghosal hematodiaphyseal dysplasia treated with steroids.
Kim SY, Ing A, Gong S, Yap KL, Bhat R. Kim SY, et al. Mol Genet Genomic Med. 2021 Mar;9(3):e1494. doi: 10.1002/mgg3.1494. Epub 2021 Feb 17. Mol Genet Genomic Med. 2021. PMID: 33595912 Free PMC article.
Patient 3 is their sister who has normal blood counts but also has the same variants in TBXAS1 as her brothers. Radiographs showed cortical bone thickening and she has not required any treatment or transfusion. CONCLUSION: We report three Caucasian siblings from non-consan …
Patient 3 is their sister who has normal blood counts but also has the same variants in TBXAS1 as her brothers. Radiographs showed co …
Expression of thromboxane synthase, TBXAS1 and the thromboxane A2 receptor, TBXA2R, in human breast cancer.
Watkins G, Douglas-Jones A, Mansel RE, Jiang WG. Watkins G, et al. Int Semin Surg Oncol. 2005 Oct 26;2:23. doi: 10.1186/1477-7800-2-23. Int Semin Surg Oncol. 2005. PMID: 16250911 Free PMC article.
There was no difference between tumour and normal tissues for TBXAS1. However, TBXA2R expression was significantly increased in grade 3 tumours(p = 0.006 vs grade 1), while TBXAS1 was significantly reduced in grade 3 tumours (p = 0.026 vs grade 1 tumours). ...While …
There was no difference between tumour and normal tissues for TBXAS1. However, TBXA2R expression was significantly increased in grade …
Thromboxane synthase (TBXAS1) polymorphisms in African-American and Caucasian populations: evidence for selective pressure.
Ulrich CM, Carlson CS, Sibert J, Poole EM, Yu JH, Wang LH, Sparks R, Potter JD, Bigler J. Ulrich CM, et al. Hum Mutat. 2005 Oct;26(4):394-5. doi: 10.1002/humu.9371. Hum Mutat. 2005. PMID: 16134166
Thromboxane synthase (TBXAS1), a cytochrome P450 enzyme, converts prostaglandin H2 into thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. Thromboxane A2 has been implicated in modulating cell cytotoxicity and in tumor growth and metastasis. Twel …
Thromboxane synthase (TBXAS1), a cytochrome P450 enzyme, converts prostaglandin H2 into thromboxane A2, a potent vasoconstrictor and …
Genetic Predictors of Drug Hypersensitivity.
Cornejo-Garcia JA, Oussalah A, Blanca M, Gueant-Rodriguez RM, Mayorga C, Waton J, Barbaud A, Gaeta F, Romano A, Gueant JL. Cornejo-Garcia JA, et al. Curr Pharm Des. 2016;22(45):6725-6733. doi: 10.2174/1381612822666160927114941. Curr Pharm Des. 2016. PMID: 27779086 Review.
The predictors of DHRs against NSAIDs are mostly linked to metabolism of eicosanoids (ALOX5, ALOX5AP, TBXAS1, PTGDR, CYSLTR1). Single nucleotide polymorphisms (SNPs) in genes involved in histamine biosynthesis and antigen presentation, HLA, could also have a role in DHRs a …
The predictors of DHRs against NSAIDs are mostly linked to metabolism of eicosanoids (ALOX5, ALOX5AP, TBXAS1, PTGDR, CYSLTR1). Single …
Association of thromboxane A1 synthase (TBXAS1) gene polymorphism with acute urticaria induced by nonsteroidal anti-inflammatory drugs.
Vidal C, Porras-Hurtado L, Cruz R, Quiralte J, Cardona V, Colás C, Castillo LF, Marcos C, Soto T, Lopez-Abad R, Hernández D, Audicana MT, Armisén M, Rodríguez V, Perez-Carral C, Moreno E, Cabañes R, Corominas M, Parra A, Lobera T, Quiñones D, Ojeda P, Luna I, Torres M, Carracedo A. Vidal C, et al. J Allergy Clin Immunol. 2013 Oct;132(4):989-91. doi: 10.1016/j.jaci.2013.04.045. Epub 2013 Jun 12. J Allergy Clin Immunol. 2013. PMID: 23763970 No abstract available.
79 results