PubMed

The effects of cholesterol ester transfer protein inhibition on cholesterol efflux.

Tall AR.

Am J Cardiol. 2009 Nov 16;104(10 Suppl):39E-45E.PMID: 19895943 [PubMed - in process]Related articles

Defective phagocytosis of apoptotic cells by macrophages in atherosclerotic lesions of ob/ob mice and reversal by a fish oil diet.

Li S, Sun Y, Liang CP, Thorp EB, Han S, Jehle AW, Saraswathi V, Pridgen B, Kanter JE, Li R, Welch CL, Hasty AH, Bornfeldt KE, Breslow JL, Tabas I, Tall AR.

Circ Res. 2009 Nov 20;105(11):1072-82. Epub 2009 Oct 15.PMID: 19834009 [PubMed - in process]Related articles

Increased HDL cholesterol and apoA-I in humans and mice treated with a novel SR-BI inhibitor.

Masson D, Koseki M, Ishibashi M, Larson CJ, Miller SG, King BD, Tall AR.

Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2054-60. Epub 2009 Oct 8.PMID: 19815817 [PubMed - in process]Related articles

Role of HDL, ABCA1, and ABCG1 Transporters in Cholesterol Efflux and Immune Responses.

Yvan-Charvet L, Wang N, Tall AR.

Arterioscler Thromb Vasc Biol. 2009 Oct 1. [Epub ahead of print]PMID: 19797709 [PubMed - as supplied by publisher]Related articles

Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice.

Seimon TA, Wang Y, Han S, Senokuchi T, Schrijvers DM, Kuriakose G, Tall AR, Tabas IA.

J Clin Invest. 2009 Apr;119(4):886-98. doi: 10.1172/JCI37262. Epub 2009 Mar 16.PMID: 19287091 [PubMed - indexed for MEDLINE]Related articlesFree article

Hepatic insulin signaling regulates VLDL secretion and atherogenesis in mice.

Han S, Liang CP, Westerterp M, Senokuchi T, Welch CL, Wang Q, Matsumoto M, Accili D, Tall AR.

J Clin Invest. 2009 Apr;119(4):1029-41. doi: 10.1172/JCI36523. Epub 2009 Mar 9.PMID: 19273907 [PubMed - indexed for MEDLINE]Related articlesFree article

Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K.

Sun Y, Ishibashi M, Seimon T, Lee M, Sharma SM, Fitzgerald KA, Samokhin AO, Wang Y, Sayers S, Aikawa M, Jerome WG, Ostrowski MC, Bromme D, Libby P, Tabas IA, Welch CL, Tall AR.

Circ Res. 2009 Feb 27;104(4):455-65. Epub 2009 Jan 2.PMID: 19122179 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of plasma lipid transfer proteins in lipoprotein metabolism and atherogenesis.

Masson D, Jiang XC, Lagrost L, Tall AR.

J Lipid Res. 2009 Apr;50 Suppl:S201-6. Epub 2008 Nov 20.PMID: 19023137 [PubMed - indexed for MEDLINE]Related articles

ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet.

Terasaka N, Yu S, Yvan-Charvet L, Wang N, Mzhavia N, Langlois R, Pagler T, Li R, Welch CL, Goldberg IJ, Tall AR.

J Clin Invest. 2008 Nov;118(11):3701-13. Epub 2008 Oct 16.PMID: 18924609 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions.

Yvan-Charvet L, Welch C, Pagler TA, Ranalletta M, Lamkanfi M, Han S, Ishibashi M, Li R, Wang N, Tall AR.

Circulation. 2008 Oct 28;118(18):1837-47. Epub 2008 Oct 13.PMID: 18852364 [PubMed - indexed for MEDLINE]Related articlesFree article

Athsq1 is an atherosclerosis modifier locus with dramatic effects on lesion area and prominent accumulation of versican.

Seidelmann SB, Kuo C, Pleskac N, Molina J, Sayers S, Li R, Zhou J, Johnson P, Braun K, Chan C, Teupser D, Breslow JL, Wight TN, Tall AR, Welch CL.

Arterioscler Thromb Vasc Biol. 2008 Dec;28(12):2180-6. Epub 2008 Sep 25.PMID: 18818413 [PubMed - indexed for MEDLINE]Related articlesFree article

Forkhead transcription factors (FoxOs) promote apoptosis of insulin-resistant macrophages during cholesterol-induced endoplasmic reticulum stress.

Senokuchi T, Liang CP, Seimon TA, Han S, Matsumoto M, Banks AS, Paik JH, DePinho RA, Accili D, Tabas I, Tall AR.

Diabetes. 2008 Nov;57(11):2967-76. Epub 2008 Aug 26.PMID: 18728232 [PubMed - indexed for MEDLINE]Related articlesFree article

HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis.

Tall AR, Yvan-Charvet L, Terasaka N, Pagler T, Wang N.

Cell Metab. 2008 May;7(5):365-75. Review.PMID: 18460328 [PubMed - indexed for MEDLINE]Related articles

Cholesterol efflux pathways and other potential mechanisms involved in the athero-protective effect of high density lipoproteins.

Tall AR.

J Intern Med. 2008 Mar;263(3):256-73. Review.PMID: 18271871 [PubMed - indexed for MEDLINE]Related articles

ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain.

Wang N, Yvan-Charvet L, Lütjohann D, Mulder M, Vanmierlo T, Kim TW, Tall AR.

FASEB J. 2008 Apr;22(4):1073-82. Epub 2007 Nov 26.PMID: 18039927 [PubMed - indexed for MEDLINE]Related articlesFree article

Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice.

Yvan-Charvet L, Ranalletta M, Wang N, Han S, Terasaka N, Li R, Welch C, Tall AR.

J Clin Invest. 2007 Dec;117(12):3900-8.PMID: 17992262 [PubMed - indexed for MEDLINE]Related articlesFree article

Spontaneous atherothrombosis and medial degradation in Apoe-/-, Npc1-/- mice.

Welch CL, Sun Y, Arey BJ, Lemaitre V, Sharma N, Ishibashi M, Sayers S, Li R, Gorelik A, Pleskac N, Collins-Fletcher K, Yasuda Y, Bromme D, D'Armiento JM, Ogletree ML, Tall AR.

Circulation. 2007 Nov 20;116(21):2444-52. Epub 2007 Nov 5.PMID: 17984379 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of torcetrapib in patients at high risk for coronary events.

Barter PJ, Caulfield M, Eriksson M, Grundy SM, Kastelein JJ, Komajda M, Lopez-Sendon J, Mosca L, Tardif JC, Waters DD, Shear CL, Revkin JH, Buhr KA, Fisher MR, Tall AR, Brewer B; ILLUMINATE Investigators.

N Engl J Med. 2007 Nov 22;357(21):2109-22. Epub 2007 Nov 5.PMID: 17984165 [PubMed - indexed for MEDLINE]Related articlesFree article

SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL.

Yvan-Charvet L, Pagler TA, Wang N, Senokuchi T, Brundert M, Li H, Rinninger F, Tall AR.

J Lipid Res. 2008 Jan;49(1):107-14. Epub 2007 Oct 24.PMID: 17960026 [PubMed - indexed for MEDLINE]Related articlesFree article

High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1.

Terasaka N, Wang N, Yvan-Charvet L, Tall AR.

Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):15093-8. Epub 2007 Sep 10.PMID: 17846428 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo.

Wang X, Collins HL, Ranalletta M, Fuki IV, Billheimer JT, Rothblat GH, Tall AR, Rader DJ.

J Clin Invest. 2007 Aug;117(8):2216-24.PMID: 17657311 [PubMed - indexed for MEDLINE]Related articlesFree article

Pivotal advance: macrophages become resistant to cholesterol-induced death after phagocytosis of apoptotic cells.

Cui D, Thorp E, Li Y, Wang N, Yvan-Charvet L, Tall AR, Tabas I.

J Leukoc Biol. 2007 Nov;82(5):1040-50. Epub 2007 Jun 18.PMID: 17576822 [PubMed - indexed for MEDLINE]Related articlesFree article

The macrophage at the crossroads of insulin resistance and atherosclerosis.

Liang CP, Han S, Senokuchi T, Tall AR.

Circ Res. 2007 Jun 8;100(11):1546-55. Review.PMID: 17556668 [PubMed - indexed for MEDLINE]Related articlesFree article

CETP inhibitors to increase HDL cholesterol levels.

Tall AR.

N Engl J Med. 2007 Mar 29;356(13):1364-6. Epub 2007 Mar 26. No abstract available. PMID: 17387130 [PubMed - indexed for MEDLINE]Related articles

HDL proteomics: pot of gold or Pandora's box?

Reilly MP, Tall AR.

J Clin Invest. 2007 Mar;117(3):595-8.PMID: 17332889 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of cholesteryl ester transfer protein by torcetrapib modestly increases macrophage cholesterol efflux to HDL.

Yvan-Charvet L, Matsuura F, Wang N, Bamberger MJ, Nguyen T, Rinninger F, Jiang XC, Shear CL, Tall AR.

Arterioscler Thromb Vasc Biol. 2007 May;27(5):1132-8. Epub 2007 Feb 22.PMID: 17322101 [PubMed - indexed for MEDLINE]Related articlesFree article

The failure of torcetrapib: was it the molecule or the mechanism?

Tall AR, Yvan-Charvet L, Wang N.

Arterioscler Thromb Vasc Biol. 2007 Feb;27(2):257-60. No abstract available. PMID: 17229967 [PubMed - indexed for MEDLINE]Related articlesFree article

Change in lipid profile in celiac disease: beneficial effect of gluten-free diet.

Brar P, Kwon GY, Holleran S, Bai D, Tall AR, Ramakrishnan R, Green PH.

Am J Med. 2006 Sep;119(9):786-90.PMID: 16945614 [PubMed - indexed for MEDLINE]Related articles

Decreased atherosclerosis in low-density lipoprotein receptor knockout mice transplanted with Abcg1-/- bone marrow.

Ranalletta M, Wang N, Han S, Yvan-Charvet L, Welch C, Tall AR.

Arterioscler Thromb Vasc Biol. 2006 Oct;26(10):2308-15. Epub 2006 Aug 17.PMID: 16917103 [PubMed - indexed for MEDLINE]Related articlesFree article

ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages.

Jehle AW, Gardai SJ, Li S, Linsel-Nitschke P, Morimoto K, Janssen WJ, Vandivier RW, Wang N, Greenberg S, Dale BM, Qin C, Henson PM, Tall AR.

J Cell Biol. 2006 Aug 14;174(4):547-56.PMID: 16908670 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose tissue-specific CETP expression in mice: impact on plasma lipoprotein metabolism.

Zhou H, Li Z, Hojjati MR, Jang D, Beyer TP, Cao G, Tall AR, Jiang XC.

J Lipid Res. 2006 Sep;47(9):2011-9. Epub 2006 Jun 2.PMID: 16751623 [PubMed - indexed for MEDLINE]Related articlesFree article

HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway.

Matsuura F, Wang N, Chen W, Jiang XC, Tall AR.

J Clin Invest. 2006 May;116(5):1435-42.PMID: 16670775 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrophage insulin receptor deficiency increases ER stress-induced apoptosis and necrotic core formation in advanced atherosclerotic lesions.

Han S, Liang CP, DeVries-Seimon T, Ranalletta M, Welch CL, Collins-Fletcher K, Accili D, Tabas I, Tall AR.

Cell Metab. 2006 Apr;3(4):257-66.PMID: 16581003 [PubMed - indexed for MEDLINE]Related articles

LXR-induced redistribution of ABCG1 to plasma membrane in macrophages enhances cholesterol mass efflux to HDL.

Wang N, Ranalletta M, Matsuura F, Peng F, Tall AR.

Arterioscler Thromb Vasc Biol. 2006 Jun;26(6):1310-6. Epub 2006 Mar 23.PMID: 16556852 [PubMed - indexed for MEDLINE]Related articlesFree article

Protease variants, LDL, and coronary heart disease.

Tall AR.

N Engl J Med. 2006 Mar 23;354(12):1310-2. No abstract available. PMID: 16554535 [PubMed - indexed for MEDLINE]Related articles

TNFalpha induces ABCA1 through NF-kappaB in macrophages and in phagocytes ingesting apoptotic cells.

Gerbod-Giannone MC, Li Y, Holleboom A, Han S, Hsu LC, Tabas I, Tall AR.

Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3112-7. Epub 2006 Feb 21.PMID: 16492740 [PubMed - indexed for MEDLINE]Related articlesFree article

Cholesterol-induced apoptotic macrophages elicit an inflammatory response in phagocytes, which is partially attenuated by the Mer receptor.

Li Y, Gerbod-Giannone MC, Seitz H, Cui D, Thorp E, Tall AR, Matsushima GK, Tabas I.

J Biol Chem. 2006 Mar 10;281(10):6707-17. Epub 2005 Dec 27.PMID: 16380374 [PubMed - indexed for MEDLINE]Related articlesFree article

Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice.

Vikramadithyan RK, Hu Y, Noh HL, Liang CP, Hallam K, Tall AR, Ramasamy R, Goldberg IJ.

J Clin Invest. 2005 Sep;115(9):2434-43. Epub 2005 Aug 25.PMID: 16127462 [PubMed - indexed for MEDLINE]Related articlesFree article

A PEST deletion mutant of ABCA1 shows impaired internalization and defective cholesterol efflux from late endosomes.

Chen W, Wang N, Tall AR.

J Biol Chem. 2005 Aug 12;280(32):29277-81. Epub 2005 Jun 10.PMID: 15951431 [PubMed - indexed for MEDLINE]Related articlesFree article

Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis.

Li Y, Schwabe RF, DeVries-Seimon T, Yao PM, Gerbod-Giannone MC, Tall AR, Davis RJ, Flavell R, Brenner DA, Tabas I.

J Biol Chem. 2005 Jun 10;280(23):21763-72. Epub 2005 Apr 11.PMID: 15826936 [PubMed - indexed for MEDLINE]Related articlesFree article

HDL as a target in the treatment of atherosclerotic cardiovascular disease.

Linsel-Nitschke P, Tall AR.

Nat Rev Drug Discov. 2005 Mar;4(3):193-205. Review. Erratum in: Nat Rev Drug Discov. 2005 Aug;4(8):648. PMID: 15738977 [PubMed - indexed for MEDLINE]Related articles

Phospholipid transfer protein (PLTP) deficiency reduces brain vitamin E content and increases anxiety in mice.

Desrumaux C, Risold PY, Schroeder H, Deckert V, Masson D, Athias A, Laplanche H, Le Guern N, Blache D, Jiang XC, Tall AR, Desor D, Lagrost L.

FASEB J. 2005 Feb;19(2):296-7. Epub 2004 Dec 2.PMID: 15576481 [PubMed - indexed for MEDLINE]Related articlesFree article

Potential role of ABCA7 in cellular lipid efflux to apoA-I.

Linsel-Nitschke P, Jehle AW, Shan J, Cao G, Bacic D, Lan D, Wang N, Tall AR.

J Lipid Res. 2005 Jan;46(1):86-92. Epub 2004 Nov 1.PMID: 15520449 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative trait locus mapping of genetic modifiers of metabolic syndrome and atherosclerosis in low-density lipoprotein receptor-deficient mice: identification of a locus for metabolic syndrome and increased atherosclerosis on chromosome 4.

Seidelmann SB, De Luca C, Leibel RL, Breslow JL, Tall AR, Welch CL.

Arterioscler Thromb Vasc Biol. 2005 Jan;25(1):204-10. Epub 2004 Oct 28.PMID: 15514201 [PubMed - indexed for MEDLINE]Related articlesFree article

ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins.

Wang N, Lan D, Chen W, Matsuura F, Tall AR.

Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9774-9. Epub 2004 Jun 21.PMID: 15210959 [PubMed - indexed for MEDLINE]Related articlesFree article

C-reactive protein reassessed.

Tall AR.

N Engl J Med. 2004 Apr 1;350(14):1450-2. No abstract available. PMID: 15070796 [PubMed - indexed for MEDLINE]Related articles

Increased CD36 protein as a response to defective insulin signaling in macrophages.

Liang CP, Han S, Okamoto H, Carnemolla R, Tabas I, Accili D, Tall AR.

J Clin Invest. 2004 Mar;113(5):764-73.PMID: 14991075 [PubMed - indexed for MEDLINE]Related articlesFree article

A prospective study of HDL-C and cholesteryl ester transfer protein gene mutations and the risk of coronary heart disease in the elderly.

Curb JD, Abbott RD, Rodriguez BL, Masaki K, Chen R, Sharp DS, Tall AR.

J Lipid Res. 2004 May;45(5):948-53. Epub 2004 Feb 16.PMID: 14967821 [PubMed - indexed for MEDLINE]Related articlesFree article

Haplotypes of the cholesteryl ester transfer protein gene predict lipid-modifying response to statin therapy.

Winkelmann BR, Hoffmann MM, Nauck M, Kumar AM, Nandabalan K, Judson RS, Boehm BO, Tall AR, Ruaño G, März W.

Pharmacogenomics J. 2003;3(5):284-96.PMID: 14583798 [PubMed - indexed for MEDLINE]Related articles

Retinoic acid receptor-mediated induction of ABCA1 in macrophages.

Costet P, Lalanne F, Gerbod-Giannone MC, Molina JR, Fu X, Lund EG, Gudas LJ, Tall AR.

Mol Cell Biol. 2003 Nov;23(21):7756-66.PMID: 14560020 [PubMed - indexed for MEDLINE]Related articlesFree article