PubMed

Mechanisms of immune complex-mediated neutrophil recruitment and tissue injury.

Mayadas TN, Tsokos GC, Tsuboi N.

Circulation. 2009 Nov 17;120(20):2012-24. No abstract available. PMID: 19917895 [PubMed - in process]Related articles

Human TCR-alpha beta+ CD4- CD8- T cells can derive from CD8+ T cells and display an inflammatory effector phenotype.

Crispín JC, Tsokos GC.

J Immunol. 2009 Oct 1;183(7):4675-81. Epub 2009 Sep 4.PMID: 19734235 [PubMed - indexed for MEDLINE]Related articles

A Novel Inhibitor of the Alternative Pathway of Complement Attenuates Intestinal Ischemia/Reperfusion-Induced Injury.

Chen J, Crispín JC, Dalle Lucca J, Tsokos GC.

J Surg Res. 2009 Jun 25. [Epub ahead of print]PMID: 19691988 [PubMed - as supplied by publisher]Related articles

The role of IL-23/IL-17 axis in lupus nephritis.

Zhang Z, Kyttaris VC, Tsokos GC.

J Immunol. 2009 Sep 1;183(5):3160-9. Epub 2009 Aug 5.PMID: 19657089 [PubMed - indexed for MEDLINE]Related articles

Interleukin-17 and systemic lupus erythematosus: current concepts.

Nalbandian A, Crispín JC, Tsokos GC.

Clin Exp Immunol. 2009 Aug;157(2):209-15. Review.PMID: 19604260 [PubMed - indexed for MEDLINE]Related articles

Suppression of murine SLE by oral anti-CD3: inducible CD4+CD25-LAP+ regulatory T cells control the expansion of IL-17+ follicular helper T cells.

Wu HY, Center EM, Tsokos GC, Weiner HL.

Lupus. 2009 Jun;18(7):586-96.PMID: 19433458 [PubMed - indexed for MEDLINE]Related articlesFree article

Pathogenic natural antibodies recognizing annexin IV are required to develop intestinal ischemia-reperfusion injury.

Kulik L, Fleming SD, Moratz C, Reuter JW, Novikov A, Chen K, Andrews KA, Markaryan A, Quigg RJ, Silverman GJ, Tsokos GC, Holers VM.

J Immunol. 2009 May 1;182(9):5363-73.PMID: 19380783 [PubMed - indexed for MEDLINE]Related articles

B cells contribute to ischemia/reperfusion-mediated tissue injury.

Chen J, Crispín JC, Tedder TF, Dalle Lucca J, Tsokos GC.

J Autoimmun. 2009 May-Jun;32(3-4):195-200. Epub 2009 Apr 1.PMID: 19342197 [PubMed - indexed for MEDLINE]Related articles

The cyclic AMP response element modulator {alpha} suppresses CD86 expression and APC function.

Ahlmann M, Varga G, Sturm K, Lippe R, Benedyk K, Viemann D, Scholzen T, Ehrchen J, Müller FU, Seidl M, Matus M, Tsokos GC, Roth J, Tenbrock K.

J Immunol. 2009 Apr 1;182(7):4167-74. Erratum in: J Immunol. 2009 Jul 1;183(1):770. PMID: 19299714 [PubMed - indexed for MEDLINE]Related articles

Methylation status of CpG islands flanking a cAMP response element motif on the protein phosphatase 2Ac alpha promoter determines CREB binding and activity.

Sunahori K, Juang YT, Tsokos GC.

J Immunol. 2009 Feb 1;182(3):1500-8.PMID: 19155497 [PubMed - indexed for MEDLINE]Related articles

Ischemia-mediated aggregation of the actin cytoskeleton is one of the major initial events resulting in ischemia-reperfusion injury.

Shi T, Moulton VR, Lapchak PH, Deng GM, Dalle Lucca JJ, Tsokos GC.

Am J Physiol Gastrointest Liver Physiol. 2009 Feb;296(2):G339-47. Epub 2008 Dec 18.PMID: 19095765 [PubMed - indexed for MEDLINE]Related articles

The role of complement in the antiphospholipid syndrome-associated pathology.

Avalos I, Tsokos GC.

Clin Rev Allergy Immunol. 2009 Jun;36(2-3):141-4. Review.PMID: 19067251 [PubMed - indexed for MEDLINE]Related articles

IL-17 producing CD4+ T cells mediate accelerated ischemia/reperfusion-induced injury in autoimmunity-prone mice.

Edgerton C, Crispín JC, Moratz CM, Bettelli E, Oukka M, Simovic M, Zacharia A, Egan R, Chen J, Dalle Lucca JJ, Juang YT, Tsokos GC.

Clin Immunol. 2009 Mar;130(3):313-21. Epub 2008 Dec 5.PMID: 19058762 [PubMed - indexed for MEDLINE]Related articles

Expanded double negative T cells in patients with systemic lupus erythematosus produce IL-17 and infiltrate the kidneys.

Crispín JC, Oukka M, Bayliss G, Cohen RA, Van Beek CA, Stillman IE, Kyttaris VC, Juang YT, Tsokos GC.

J Immunol. 2008 Dec 15;181(12):8761-6.PMID: 19050297 [PubMed - indexed for MEDLINE]Related articles

Differential expression and molecular associations of Syk in systemic lupus erythematosus T cells.

Krishnan S, Juang YT, Chowdhury B, Magilavy A, Fisher CU, Nguyen H, Nambiar MP, Kyttaris V, Weinstein A, Bahjat R, Pine P, Rus V, Tsokos GC.

J Immunol. 2008 Dec 1;181(11):8145-52.PMID: 19018007 [PubMed - indexed for MEDLINE]Related articles

Cholera toxin B accelerates disease progression in lupus-prone mice by promoting lipid raft aggregation.

Deng GM, Tsokos GC.

J Immunol. 2008 Sep 15;181(6):4019-26.PMID: 18768857 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcriptional regulation of IL-2 in health and autoimmunity.

Crispín JC, Tsokos GC.

Autoimmun Rev. 2009 Jan;8(3):190-5. Epub 2008 Aug 24. Review.PMID: 18723131 [PubMed - indexed for MEDLINE]Related articles

PP2A dephosphorylates Elf-1 and determines the expression of CD3zeta and FcRgamma in human systemic lupus erythematosus T cells.

Juang YT, Wang Y, Jiang G, Peng HB, Ergin S, Finnell M, Magilavy A, Kyttaris VC, Tsokos GC.

J Immunol. 2008 Sep 1;181(5):3658-64.PMID: 18714041 [PubMed - indexed for MEDLINE]Related articlesFree article

Complement component C5a mediates hemorrhage-induced intestinal damage.

Fleming SD, Phillips LM, Lambris JD, Tsokos GC.

J Surg Res. 2008 Dec;150(2):196-203. Epub 2008 Mar 13.PMID: 18639891 [PubMed - indexed for MEDLINE]Related articlesFree article

T cells and in situ cryoglobulin deposition in the pathogenesis of lupus nephritis.

Cohen RA, Bayliss G, Crispin JC, Kane-Wanger GF, Van Beek CA, Kyttaris VC, Avalos I, Yu CY, Tsokos GC, Stillman IE.

Clin Immunol. 2008 Jul;128(1):1-7.PMID: 18565470 [PubMed - indexed for MEDLINE]Related articlesFree article

The RNA-stabilizing protein HuR regulates the expression of zeta chain of the human T cell receptor-associated CD3 complex.

Moulton VR, Kyttaris VC, Juang YT, Chowdhury B, Tsokos GC.

J Biol Chem. 2008 Jul 18;283(29):20037-44. Epub 2008 May 27.PMID: 18505733 [PubMed - indexed for MEDLINE]Related articlesFree article

Calcium signaling in systemic lupus erythematosus lymphocytes and its therapeutic exploitation.

Tsokos GC.

Arthritis Rheum. 2008 May;58(5):1216-9. Review. No abstract available. PMID: 18438836 [PubMed - indexed for MEDLINE]Related articlesFree article

Common variable immune deficiency (CVID) presenting as an autoimmune disease: role of memory B cells.

Haymore BR, Mikita CP, Tsokos GC.

Autoimmun Rev. 2008 Feb;7(4):309-12. Epub 2007 Dec 31. Review.PMID: 18295735 [PubMed - indexed for MEDLINE]Related articles

How signaling and gene transcription aberrations dictate the systemic lupus erythematosus T cell phenotype.

Crispín JC, Kyttaris VC, Juang YT, Tsokos GC.

Trends Immunol. 2008 Mar;29(3):110-5. Epub 2008 Feb 4. Review.PMID: 18249583 [PubMed - indexed for MEDLINE]Related articles

Novel molecular targets in the treatment of systemic lupus erythematosus.

Crispín JC, Tsokos GC.

Autoimmun Rev. 2008 Jan;7(3):256-61. Epub 2007 Dec 4. Review.PMID: 18190888 [PubMed - indexed for MEDLINE]Related articlesFree article

Systemic lupus erythematosus: new molecular targets.

Crispín JC, Kyttaris V, Juang YT, Tsokos GC.

Ann Rheum Dis. 2007 Nov;66 Suppl 3:iii65-9. Review.PMID: 17934100 [PubMed - indexed for MEDLINE]Related articles

C3d-defined complement receptor-binding peptide p28 conjugated to circumsporozoite protein provides protection against Plasmodium berghei.

Bergmann-Leitner ES, Duncan EH, Leitner WW, Neutzner A, Savranskaya T, Angov E, Tsokos GC.

Vaccine. 2007 Nov 7;25(45):7732-6. Epub 2007 Sep 4.PMID: 17931754 [PubMed - indexed for MEDLINE]Related articles

Elf-1 binds to GGAA elements on the FcRgamma promoter and represses its expression.

Juang YT, Sumibcay L, Tolnay M, Wang Y, Kyttaris VC, Tsokos GC.

J Immunol. 2007 Oct 1;179(7):4884-9.PMID: 17878388 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of the CTLA-4 gene in human lymphocytes is dependent on NFAT binding the proximal promoter.

Gibson HM, Hedgcock CJ, Aufiero BM, Wilson AJ, Hafner MS, Tsokos GC, Wong HK.

J Immunol. 2007 Sep 15;179(6):3831-40.PMID: 17785820 [PubMed - indexed for MEDLINE]Related articlesFree article

Proximal signaling control of human effector CD4 T cell function.

Okoye FI, Krishnan S, Chandok MR, Tsokos GC, Farber DL.

Clin Immunol. 2007 Oct;125(1):5-15. Epub 2007 Aug 9.PMID: 17692570 [PubMed - indexed for MEDLINE]Related articlesFree article

Syk kinase as a treatment target for therapy in autoimmune diseases.

Kyttaris VC, Tsokos GC.

Clin Immunol. 2007 Sep;124(3):235-7. Epub 2007 Jul 26.PMID: 17662659 [PubMed - indexed for MEDLINE]Related articlesFree article

Decay-accelerating factor attenuates remote ischemia-reperfusion-initiated organ damage.

Weeks C, Moratz C, Zacharia A, Stracener C, Egan R, Peckham R, Moore FD Jr, Tsokos GC.

Clin Immunol. 2007 Sep;124(3):311-27. Epub 2007 Jul 12.PMID: 17631050 [PubMed - indexed for MEDLINE]Related articles

Altered signal transduction in SLE T cells.

Tenbrock K, Juang YT, Kyttaris VC, Tsokos GC.

Rheumatology (Oxford). 2007 Oct;46(10):1525-30. Epub 2007 Jun 24. Review.PMID: 17586862 [PubMed - indexed for MEDLINE]Related articlesFree article

Geldanamycin inhibits hemorrhage-induced increases in caspase-3 activity: role of inducible nitric oxide synthase.

Kiang JG, Bowman PD, Lu X, Li Y, Wu BW, Loh HH, Tsen KT, Tsokos GC.

J Appl Physiol. 2007 Sep;103(3):1045-55. Epub 2007 May 24.PMID: 17525298 [PubMed - indexed for MEDLINE]Related articlesFree article

Anti-ribonucleoprotein antibodies mediate enhanced lung injury following mesenteric ischemia/reperfusion in Rag-1(-/-) mice.

Keith MP, Moratz C, Egan R, Zacharia A, Greidinger EL, Hoffman RW, Tsokos GC.

Autoimmunity. 2007 May;40(3):208-16.PMID: 17453720 [PubMed - indexed for MEDLINE]Related articles

Increased expression of STAT3 in SLE T cells contributes to enhanced chemokine-mediated cell migration.

Harada T, Kyttaris V, Li Y, Juang YT, Wang Y, Tsokos GC.

Autoimmunity. 2007 Feb;40(1):1-8.PMID: 17364491 [PubMed - indexed for MEDLINE]Related articles

Anti-RNP immunity: implications for tissue injury and the pathogenesis of connective tissue disease.

Keith MP, Moratz C, Tsokos GC.

Autoimmun Rev. 2007 Mar;6(4):232-6. Epub 2006 Aug 28. Review.PMID: 17317614 [PubMed - indexed for MEDLINE]Related articles

2006 clinical immunology school on systemic autoimmune diseases.

Katz U, Tsokos GC.

Autoimmun Rev. 2007 Mar;6(4):203. Epub 2006 Sep 7. No abstract available. PMID: 17317607 [PubMed - indexed for MEDLINE]Related articles

Increased levels of NF-ATc2 differentially regulate CD154 and IL-2 genes in T cells from patients with systemic lupus erythematosus.

Kyttaris VC, Wang Y, Juang YT, Weinstein A, Tsokos GC.

J Immunol. 2007 Feb 1;178(3):1960-6.PMID: 17237447 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphorylated ERM is responsible for increased T cell polarization, adhesion, and migration in patients with systemic lupus erythematosus.

Li Y, Harada T, Juang YT, Kyttaris VC, Wang Y, Zidanic M, Tung K, Tsokos GC.

J Immunol. 2007 Feb 1;178(3):1938-47.PMID: 17237445 [PubMed - indexed for MEDLINE]Related articlesFree article

Pathology and immunology of lupus glomerulonephritis: can we bridge the two?

Liapis H, Tsokos GC.

Int Urol Nephrol. 2007;39(1):223-31. Epub 2007 Jan 12. Review.PMID: 17219015 [PubMed - indexed for MEDLINE]Related articles

CAMP response element modulator a expression in patients with systemic lupus erythematosus.

Kyttaris VC, Wang Y, Juang YT, Weinstein A, Tsokos GC.

Lupus. 2006;15(12):840-4.PMID: 17211988 [PubMed - indexed for MEDLINE]Related articles

Systems biology in systemic lupus erythematosus: integrating genes, biology and immune function.

Kyttaris VC, Krishnan S, Tsokos GC.

Autoimmunity. 2006 Dec;39(8):705-9. Review.PMID: 17178567 [PubMed - indexed for MEDLINE]Related articles

FcRgamma chain does not replace CD3zeta chain in CD3zeta-deficient T lymphocytes of patients with gastric adenocarcinoma.

Lopez-Santalla M, Krishnan S, Valeri AP, Aguilera-Montilla N, Fisher CU, Perez-Blas M, Gutierrez-Calvo A, Lasa I, Granell-Vicent J, Tsokos GC, Martin-Villa JM.

Mol Immunol. 2007 Mar;44(9):2400-5. Epub 2006 Nov 28.PMID: 17134755 [PubMed - indexed for MEDLINE]Related articles

Stability and translation of TCR zeta mRNA are regulated by the adenosine-uridine-rich elements in splice-deleted 3' untranslated region of zeta-chain.

Chowdhury B, Krishnan S, Tsokos CG, Robertson JW, Fisher CU, Nambiar MP, Tsokos GC.

J Immunol. 2006 Dec 1;177(11):8248-57.PMID: 17114503 [PubMed - indexed for MEDLINE]Related articlesFree article

Androstenediol inhibits the trauma-hemorrhage-induced increase in caspase-3 by downregulating the inducible nitric oxide synthase pathway.

Kiang JG, Peckham RM, Duke LE, Shimizu T, Chaudry IH, Tsokos GC.

J Appl Physiol. 2007 Mar;102(3):933-41. Epub 2006 Nov 16.PMID: 17110508 [PubMed - indexed for MEDLINE]Related articlesFree article

C5-blocking antibody reduces fluid requirements and improves responsiveness to fluid infusion in hemorrhagic shock managed with hypotensive resuscitation.

Peckham RM, Handrigan MT, Bentley TB, Falabella MJ, Chrovian AD, Stahl GL, Tsokos GC.

J Appl Physiol. 2007 Feb;102(2):673-80. Epub 2006 Oct 26.PMID: 17068213 [PubMed - indexed for MEDLINE]Related articlesFree article

The transcriptional repressor cAMP response element modulator alpha interacts with histone deacetylase 1 to repress promoter activity.

Tenbrock K, Juang YT, Leukert N, Roth J, Tsokos GC.

J Immunol. 2006 Nov 1;177(9):6159-64.PMID: 17056544 [PubMed - indexed for MEDLINE]Related articlesFree article

The clinical spectrum of anti-insulin receptor antibodies and autoimmune disease.

Gilliland WR, Tsokos GC.

J Clin Rheumatol. 2001 Dec;7(6):361-2. No abstract available. PMID: 17039174 [PubMed]Related articles

Complement 3d: from molecular adjuvant to target of immune escape mechanisms.

Bergmann-Leitner ES, Leitner WW, Tsokos GC.

Clin Immunol. 2006 Nov;121(2):177-85. Epub 2006 Aug 17. Review.PMID: 16914381 [PubMed - indexed for MEDLINE]Related articles