PubMed

Treatment of scleroderma-interstitial lung disease with cyclophosphamide is associated with less progressive fibrosis on serial thoracic high-resolution CT scan than placebo: findings from the scleroderma lung study.

Goldin J, Elashoff R, Kim HJ, Yan X, Lynch D, Strollo D, Roth MD, Clements P, Furst DE, Khanna D, Vasunilashorn S, Li G, Tashkin DP.

Chest. 2009 Nov;136(5):1333-40.PMID: 19892673 [PubMed - in process]Related articles

Combination of formoterol and tiotropium in the treatment of COPD: effects on lung function.

Cazzola M, Tashkin DP.

COPD. 2009 Oct;6(5):404-15.PMID: 19863370 [PubMed - in process]Related articles

Defining disease modification in chronic obstructive pulmonary disease.

Halpin DM, Tashkin DP.

COPD. 2009 Jun;6(3):211-25.PMID: 19811377 [PubMed - in process]Related articlesFree article

Minimally important differences in the Mahler's Transition Dyspnoea Index in a large randomized controlled trial--results from the Scleroderma Lung Study.

Khanna D, Tseng CH, Furst DE, Clements PJ, Elashoff R, Roth M, Elashoff D, Tashkin DP; for Scleroderma Lung Study Investigators.

Rheumatology (Oxford). 2009 Dec;48(12):1537-40. Epub 2009 Sep 23.PMID: 19776222 [PubMed - in process]Related articlesFree article

Mortality in the 4-year trial of tiotropium (UPLIFT) in patients with chronic obstructive pulmonary disease.

Celli B, Decramer M, Kesten S, Liu D, Mehra S, Tashkin DP; UPLIFT Study Investigators.

Am J Respir Crit Care Med. 2009 Nov 15;180(10):948-55. Epub 2009 Sep 3.PMID: 19729663 [PubMed - in process]Related articles

Long-term efficacy of tiotropium in relation to smoking status in the UPLIFT trial.

Tashkin DP, Celli B, Kesten S, Lystig T, Mehra S, Decramer M.

Eur Respir J. 2009 Aug 28. [Epub ahead of print]PMID: 19717481 [PubMed - as supplied by publisher]Related articles

Effect of tiotropium on outcomes in patients with moderate chronic obstructive pulmonary disease (UPLIFT): a prespecified subgroup analysis of a randomised controlled trial.

Decramer M, Celli B, Kesten S, Lystig T, Mehra S, Tashkin DP; UPLIFT investigators.

Lancet. 2009 Oct 3;374(9696):1171-8. Epub 2009 Aug 27.PMID: 19716598 [PubMed - indexed for MEDLINE]Related articles

Cardiovascular Safety of Tiotropium in Patients With COPD.

Celli B, Decramer M, Leimer I, Vogel U, Kesten S, Tashkin DP.

Chest. 2009 Jul 10. [Epub ahead of print]PMID: 19592475 [PubMed - as supplied by publisher]Related articles

Recruitment strategies for a lung cancer chemoprevention trial involving ex-smokers.

Kye SH, Tashkin DP, Roth MD, Adams B, Nie WX, Mao JT.

Contemp Clin Trials. 2009 Sep;30(5):464-72. Epub 2009 Jun 7.PMID: 19508900 [PubMed - in process]Related articles

Does smoking marijuana increase the risk of chronic obstructive pulmonary disease?

Tashkin DP.

CMAJ. 2009 Apr 14;180(8):797-8. No abstract available. PMID: 19364782 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy and tolerability of budesonide/formoterol in one hydrofluoroalkane pressurized metered-dose inhaler in patients with chronic obstructive pulmonary disease: results from a 1-year randomized controlled clinical trial.

Rennard SI, Tashkin DP, McElhattan J, Goldman M, Ramachandran S, Martin UJ, Silkoff PE.

Drugs. 2009;69(5):549-65. doi: 10.2165/00003495-200969050-00004.PMID: 19368417 [PubMed - indexed for MEDLINE]Related articles

Current concepts in disease-modifying therapy for systemic sclerosis-associated interstitial lung disease: lessons from clinical trials.

Au K, Khanna D, Clements PJ, Furst DE, Tashkin DP.

Curr Rheumatol Rep. 2009 Apr;11(2):111-9. Review.PMID: 19296883 [PubMed - indexed for MEDLINE]Related articles

Surfactant protein D and KL-6 as serum biomarkers of interstitial lung disease in patients with scleroderma.

Hant FN, Ludwicka-Bradley A, Wang HJ, Li N, Elashoff R, Tashkin DP, Silver RM; Scleroderma Lung Study Research Group.

J Rheumatol. 2009 Apr;36(4):773-80. Epub 2009 Mar 13.PMID: 19286849 [PubMed - indexed for MEDLINE]Related articles

Smoking cessation in chronic obstructive pulmonary disease.

Tashkin DP, Murray RP.

Respir Med. 2009 Jul;103(7):963-74. Epub 2009 Mar 14.PMID: 19285850 [PubMed - in process]Related articles

Formoterol and tiotropium compared with tiotropium alone for treatment of COPD.

Tashkin DP, Pearle J, Iezzoni D, Varghese ST.

COPD. 2009 Feb;6(1):17-25.PMID: 19229704 [PubMed - indexed for MEDLINE]Related articles

Effects of arformoterol twice daily, tiotropium once daily, and their combination in patients with COPD.

Tashkin DP, Donohue JF, Mahler DA, Huang H, Goodwin E, Schaefer K, Hanrahan JP, Andrews WT.

Respir Med. 2009 Apr;103(4):516-24. Epub 2009 Feb 8.PMID: 19208459 [PubMed - in process]Related articles

Differential modulation of leukotriene B4 synthesis and degradation in human bronchoalveolar lavage cells by lipopolysaccharide and tobacco smoke.

Mao JT, Tashkin DP, Tsu IH, Serio KJ.

Cancer Prev Res (Phila Pa). 2008 Sep;1(4):266-74.PMID: 19138970 [PubMed - indexed for MEDLINE]Related articles

The role of tiotropium in the hospital management of exacerbation of chronic obstructive pulmonary disease.

Tashkin DP.

Respir Care. 2008 Dec;53(12):1657-9. No abstract available. PMID: 19025697 [PubMed - indexed for MEDLINE]Related articlesFree article

Associations between variants of the 8q24 chromosome and nine smoking-related cancer sites.

Park SL, Chang SC, Cai L, Cordon-Cardo C, Ding BG, Greenland S, Hussain SK, Jiang Q, Liu S, Lu ML, Mao JT, Morgenstern H, Mu LN, Ng LJ, Pantuck A, Rao J, Reuter VE, Tashkin DP, You NC, Yu CQ, Yu SZ, Zhao JK, Belldegrun A, Zhang ZF.

Cancer Epidemiol Biomarkers Prev. 2008 Nov;17(11):3193-202.PMID: 18990762 [PubMed - indexed for MEDLINE]Related articlesFree article

Time course and degree of hyperinflation with metronome-paced tachypnea in COPD patients.

Weigt SS, Abrazado M, Kleerup EC, Tashkin DP, Cooper CB.

COPD. 2008 Oct;5(5):298-304.PMID: 18972278 [PubMed - indexed for MEDLINE]Related articles

A 4-year trial of tiotropium in chronic obstructive pulmonary disease.

Tashkin DP, Celli B, Senn S, Burkhart D, Kesten S, Menjoge S, Decramer M; UPLIFT Study Investigators.

N Engl J Med. 2008 Oct 9;359(15):1543-54. Epub 2008 Oct 5.PMID: 18836213 [PubMed - indexed for MEDLINE]Related articlesFree article

Circulating fibronectin to C-reactive protein ratio and mortality: a biomarker in COPD?

Man SF, Xing L, Connett JE, Anthonisen NR, Wise RA, Tashkin DP, Zhang X, Vessey R, Walker TG, Celli BR, Sin DD.

Eur Respir J. 2008 Dec;32(6):1451-7. Epub 2008 Sep 17.PMID: 18799503 [PubMed - indexed for MEDLINE]Related articles

The partners--airflow obstruction, emphysema, and lung cancer.

Dubinett SM, Aberle DR, Tashkin DP, Mao JT.

Am J Respir Crit Care Med. 2008 Oct 1;178(7):665-6. No abstract available. PMID: 18796652 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy and safety of budesonide and formoterol in one pressurized metered-dose inhaler in patients with moderate to very severe chronic obstructive pulmonary disease: results of a 6-month randomized clinical trial.

Tashkin DP, Rennard SI, Martin P, Ramachandran S, Martin UJ, Silkoff PE, Goldman M.

Drugs. 2008;68(14):1975-2000.PMID: 18778120 [PubMed - indexed for MEDLINE]Related articles

High-resolution CT scan findings in patients with symptomatic scleroderma-related interstitial lung disease.

Goldin JG, Lynch DA, Strollo DC, Suh RD, Schraufnagel DE, Clements PJ, Elashoff RM, Furst DE, Vasunilashorn S, McNitt-Gray MF, Brown MS, Roth MD, Tashkin DP; Scleroderma Lung Study Research Group.

Chest. 2008 Aug;134(2):358-67. Epub 2008 Jul 18.PMID: 18641099 [PubMed - indexed for MEDLINE]Related articlesFree article

Oral cyclophosphamide for active scleroderma lung disease: a decision analysis.

Khanna D, Furst DE, Clements PJ, Tashkin DP, Eckman MH.

Med Decis Making. 2008 Nov-Dec;28(6):926-37. Epub 2008 Apr 28.PMID: 18443209 [PubMed - indexed for MEDLINE]Related articles

Dietary flavonoid intake and lung cancer--a population-based case-control study.

Cui Y, Morgenstern H, Greenland S, Tashkin DP, Mao JT, Cai L, Cozen W, Mack TM, Lu QY, Zhang ZF.

Cancer. 2008 May 15;112(10):2241-8.PMID: 18327817 [PubMed - indexed for MEDLINE]Related articlesFree article

Concomitant treatment with nebulized formoterol and tiotropium in subjects with COPD: a placebo-controlled trial.

Tashkin DP, Littner M, Andrews CP, Tomlinson L, Rinehart M, Denis-Mize K.

Respir Med. 2008 Apr;102(4):479-87. Epub 2008 Feb 6.PMID: 18258423 [PubMed - indexed for MEDLINE]Related articles

Bronchodilator responsiveness in patients with COPD.

Tashkin DP, Celli B, Decramer M, Liu D, Burkhart D, Cassino C, Kesten S.

Eur Respir J. 2008 Apr;31(4):742-50. Epub 2008 Feb 6.PMID: 18256071 [PubMed - indexed for MEDLINE]Related articlesFree article

Oral vs IV corticosteroids for in-hospital treatment of COPD exacerbations.

Tashkin DP.

Chest. 2007 Dec;132(6):1728-9. No abstract available. PMID: 18079214 [PubMed - indexed for MEDLINE]Related articlesFree article

A case-control study of the association of the polymorphisms and haplotypes of DNA ligase I with lung and upper-aerodigestive-tract cancers.

Lee YC, Morgenstern H, Greenland S, Tashkin DP, Papp J, Sinsheimer J, Cao W, Hashibe M, You NC, Mao JT, Cozen W, Mack TM, Zhang ZF.

Int J Cancer. 2008 Apr 1;122(7):1630-8.PMID: 18059021 [PubMed - indexed for MEDLINE]Related articlesFree article

Bronchoalveolar lavage and response to cyclophosphamide in scleroderma interstitial lung disease.

Strange C, Bolster MB, Roth MD, Silver RM, Theodore A, Goldin J, Clements P, Chung J, Elashoff RM, Suh R, Smith EA, Furst DE, Tashkin DP; Scleroderma Lung Study Research Group.

Am J Respir Crit Care Med. 2008 Jan 1;177(1):91-8. Epub 2007 Sep 27.PMID: 17901414 [PubMed - indexed for MEDLINE]Related articlesFree article

Pharmacologic therapy: novel approaches for chronic obstructive pulmonary disease.

Bailey WC, Tashkin DP.

Proc Am Thorac Soc. 2007 Oct 1;4(7):543-8. Review.PMID: 17878467 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of 1-year treatment with cyclophosphamide on outcomes at 2 years in scleroderma lung disease.

Tashkin DP, Elashoff R, Clements PJ, Roth MD, Furst DE, Silver RM, Goldin J, Arriola E, Strange C, Bolster MB, Seibold JR, Riley DJ, Hsu VM, Varga J, Schraufnagel D, Theodore A, Simms R, Wise R, Wigley F, White B, Steen V, Read C, Mayes M, Parsley E, Mubarak K, Connolly MK, Golden J, Olman M, Fessler B, Rothfield N, Metersky M, Khanna D, Li N, Li G; Scleroderma Lung Study Research Group.

Am J Respir Crit Care Med. 2007 Nov 15;176(10):1026-34. Epub 2007 Aug 23.PMID: 17717203 [PubMed - indexed for MEDLINE]Related articlesFree article

Optimizing treatment of chronic obstructive pulmonary disease: an assessment of current therapies.

Wise RA, Tashkin DP.

Am J Med. 2007 Aug;120(8 Suppl 1):S4-13. Review.PMID: 17678942 [PubMed - indexed for MEDLINE]Related articles

Preventing chronic obstructive pulmonary disease: what is known and what needs to be done to make a difference to the patient?

Wise RA, Tashkin DP.

Am J Med. 2007 Aug;120(8 Suppl 1):S14-22. Review.PMID: 17678939 [PubMed - indexed for MEDLINE]Related articles

Effect of occupational exposures on decline of lung function in early chronic obstructive pulmonary disease.

Harber P, Tashkin DP, Simmons M, Crawford L, Hnizdo E, Connett J; Lung Health Study Group.

Am J Respir Crit Care Med. 2007 Nov 15;176(10):994-1000. Epub 2007 Jul 12.PMID: 17626912 [PubMed - indexed for MEDLINE]Related articlesFree article

Scleroderma lung study (SLS): differences in the presentation and course of patients with limited versus diffuse systemic sclerosis.

Clements PJ, Roth MD, Elashoff R, Tashkin DP, Goldin J, Silver RM, Sterz M, Seibold JR, Schraufnagel D, Simms RW, Bolster M, Wise RA, Steen V, Mayes MD, Connelly K, Metersky M, Furst DE; Scleroderma Lung Study Group.

Ann Rheum Dis. 2007 Dec;66(12):1641-7. Epub 2007 May 7.PMID: 17485423 [PubMed - indexed for MEDLINE]Related articles

Impact of oral cyclophosphamide on health-related quality of life in patients with active scleroderma lung disease: results from the scleroderma lung study.

Khanna D, Yan X, Tashkin DP, Furst DE, Elashoff R, Roth MD, Silver R, Strange C, Bolster M, Seibold JR, Riley DJ, Hsu VM, Varga J, Schraufnagel DE, Theodore A, Simms R, Wise R, Wigley F, White B, Steen V, Read C, Mayes M, Parsley E, Mubarak K, Connolly MK, Golden J, Olman M, Fessler B, Rothfield N, Metersky M, Clements PJ; Scleroderma Lung Study Group.

Arthritis Rheum. 2007 May;56(5):1676-84.PMID: 17469162 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparing COPD treatment: nebulizer, metered dose inhaler, and concomitant therapy.

Tashkin DP, Klein GL, Colman SS, Zayed H, Schonfeld WH.

Am J Med. 2007 May;120(5):435-41.PMID: 17466655 [PubMed - indexed for MEDLINE]Related articles

Menthol cigarettes and health risks in Lung Health Study data.

Murray RP, Connett JE, Skeans MA, Tashkin DP.

Nicotine Tob Res. 2007 Jan;9(1):101-7.PMID: 17365741 [PubMed - indexed for MEDLINE]Related articles

Clinical trial design considerations in assessing long-term functional impacts of tiotropium in COPD: the UPLIFT trial.

Decramer M, Celli B, Tashkin DP, Pauwels RA, Burkhart D, Cassino C, Kesten S.

COPD. 2004;1(2):303-12.PMID: 17136995 [PubMed - indexed for MEDLINE]Related articles

Small airways response to naturalistic cat allergen exposure in subjects with asthma.

Zeidler MR, Goldin JG, Kleerup EC, Kim HJ, Truong DA, Gjertson DW, Kennedy NJ, Newman KB, Tashkin DP, Silverman JM, Corren J.

J Allergy Clin Immunol. 2006 Nov;118(5):1075-81. Epub 2006 Sep 8.PMID: 17088132 [PubMed - indexed for MEDLINE]Related articles

Does quality of life of COPD patients as measured by the generic EuroQol five-dimension questionnaire differentiate between COPD severity stages?

Rutten-van Mölken MP, Oostenbrink JB, Tashkin DP, Burkhart D, Monz BU.

Chest. 2006 Oct;130(4):1117-28.PMID: 17035446 [PubMed - indexed for MEDLINE]Related articlesFree article

Marijuana use and the risk of lung and upper aerodigestive tract cancers: results of a population-based case-control study.

Hashibe M, Morgenstern H, Cui Y, Tashkin DP, Zhang ZF, Cozen W, Mack TM, Greenland S.

Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):1829-34.PMID: 17035389 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of patient-centered outcomes in the course of chronic obstructive pulmonary disease: how long-term studies contribute to our understanding.

Tashkin DP.

Am J Med. 2006 Oct;119(10 Suppl 1):63-72. Review.PMID: 16996901 [PubMed - indexed for MEDLINE]Related articles

The role of patient-centered outcomes in defining the clinical course of chronic obstructive pulmonary disease. Introduction.

Tashkin DP.

Am J Med. 2006 Oct;119(10 Suppl 1):1-3. No abstract available. PMID: 16996893 [PubMed - indexed for MEDLINE]Related articles

Quitting among non-treatment-seeking marijuana users: reasons and changes in other substance use.

Copersino ML, Boyd SJ, Tashkin DP, Huestis MA, Heishman SJ, Dermand JC, Simmons MS, Gorelick DA.

Am J Addict. 2006 Jul-Aug;15(4):297-302.PMID: 16867925 [PubMed - indexed for MEDLINE]Related articles

Single-factor scoring validation for the Health Assessment Questionnaire-Disability Index (HAQ-DI) in patients with systemic sclerosis and comparison with early rheumatoid arthritis patients.

Cole JC, Khanna D, Clements PJ, Seibold JR, Tashkin DP, Paulus HE, Irwin MR, Motivala SJ, Furst DE.

Qual Life Res. 2006 Oct;15(8):1383-94. Epub 2006 Jul 7.PMID: 16826439 [PubMed - indexed for MEDLINE]Related articles

Control of airway inflammation maintained at a lower steroid dose with 100/50 microg of fluticasone propionate/salmeterol.

Jarjour NN, Wilson SJ, Koenig SM, Laviolette M, Moore WC, Davis WB, Doherty DE, Hamid Q, Israel E, Kavuru MS, Ramsdell JW, Tashkin DP, Reilly DS, Yancey SW, Edwards LD, Stauffer JL, Dorinsky PM, Djukanovic R.

J Allergy Clin Immunol. 2006 Jul;118(1):44-52. Epub 2006 Jun 2.PMID: 16815137 [PubMed - indexed for MEDLINE]Related articles