PubMed

AFM study of the interaction of cytochrome P450 2C9 with phospholipid bilayers.

Nussio MR, Voelcker NH, Miners JO, Lewis BC, Sykes MJ, Shapter JG.

Chem Phys Lipids. 2009 Nov 17. [Epub ahead of print]PMID: 19925783 [PubMed - as supplied by publisher]Related articles

A luciferase based viability assay for ATP detection in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.

Sykes ML, Avery VM.

Parasit Vectors. 2009 Nov 12;2(1):54.PMID: 19909542 [PubMed - in process]Related articlesFree article

Results of Gal-Knockout Porcine Thymokidney Xenografts.

Griesemer AD, Hirakata A, Shimizu A, Moran S, Tena A, Iwaki H, Ishikawa Y, Schule P, Arn JS, Robson SC, Fishman JA, Sykes M, Sachs DH, Yamada K.

Am J Transplant. 2009 Oct 21. [Epub ahead of print]PMID: 19845583 [PubMed - as supplied by publisher]Related articles

Development of an Alamar Blue viability assay in 384-well format for high throughput whole cell screening of Trypanosoma brucei brucei bloodstream form strain 427.

Sykes ML, Avery VM.

Am J Trop Med Hyg. 2009 Oct;81(4):665-74.PMID: 19815884 [PubMed - indexed for MEDLINE]Related articles

The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--chapter 1: Key ethical requirements and progress toward the definition of an international regulatory framework.

Cozzi E, Tallacchini M, Flanagan EB, Pierson RN 3rd, Sykes M, Vanderpool HY.

Xenotransplantation. 2009 Jul;16(4):203-14.PMID: 19799760 [PubMed - in process]Related articles

A dominant negative mutant of the E. coli RNA helicase DbpA blocks assembly of the 50S ribosomal subunit.

Sharpe Elles LM, Sykes MT, Williamson JR, Uhlenbeck OC.

Nucleic Acids Res. 2009 Oct;37(19):6503-14. Epub 2009 Sep 4.PMID: 19734347 [PubMed - in process]Related articlesFree article

Alien species in a warmer world: risks and opportunities.

Walther GR, Roques A, Hulme PE, Sykes MT, Pysek P, Kühn I, Zobel M, Bacher S, Botta-Dukát Z, Bugmann H, Czúcz B, Dauber J, Hickler T, Jarosík V, Kenis M, Klotz S, Minchin D, Moora M, Nentwig W, Ott J, Panov VE, Reineking B, Robinet C, Semenchenko V, Solarz W, Thuiller W, Vilà M, Vohland K, Settele J.

Trends Ecol Evol. 2009 Dec;24(12):686-93. Epub 2009 Aug 25.PMID: 19712994 [PubMed - in process]Related articles

B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans.

Porcheray F, Wong W, Saidman SL, De Vito J, Girouard TC, Chittenden M, Shaffer J, Tolkoff-Rubin N, Dey BR, Spitzer TR, Colvin RB, Cosimi AB, Kawai T, Sachs DH, Sykes M, Zorn E.

Am J Transplant. 2009 Sep;9(9):2126-35. Epub 2009 Jul 16.PMID: 19624570 [PubMed - in process]Related articles

Induction of human T-cell tolerance to pig Xenoantigens via thymus transplantation in mice with an established human immune system.

Habiro K, Sykes M, Yang YG.

Am J Transplant. 2009 Jun;9(6):1324-9. Epub 2009 May 20.PMID: 19459808 [PubMed - in process]Related articles

Mechanisms of transplantation tolerance in animals and humans.

Sykes M.

Transplantation. 2009 May 15;87(9 Suppl):S67-9.PMID: 19424011 [PubMed - indexed for MEDLINE]Related articles

Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice.

Brainard DM, Seung E, Frahm N, Cariappa A, Bailey CC, Hart WK, Shin HS, Brooks SF, Knight HL, Eichbaum Q, Yang YG, Sykes M, Walker BD, Freeman GJ, Pillai S, Westmoreland SV, Brander C, Luster AD, Tager AM.

J Virol. 2009 Jul;83(14):7305-21. Epub 2009 May 6.PMID: 19420076 [PubMed - indexed for MEDLINE]Related articles

A complex assembly landscape for the 30S ribosomal subunit.

Sykes MT, Williamson JR.

Annu Rev Biophys. 2009;38:197-215. Review.PMID: 19416066 [PubMed - indexed for MEDLINE]Related articles

(-)-Dibromophakellin: an alpha2B adrenoceptor agonist isolated from the Australian marine sponge, Acanthella costata.

Davis RA, Fechner GA, Sykes M, Garavelas A, Pass DM, Carroll AR, Addepalli R, Avery VM, Hooper JN, Quinn RJ.

Bioorg Med Chem. 2009 Mar 15;17(6):2497-500. Epub 2009 Feb 3.PMID: 19243956 [PubMed - indexed for MEDLINE]Related articles

Paradoxical effects of IFN-gamma in graft-versus-host disease reflect promotion of lymphohematopoietic graft-versus-host reactions and inhibition of epithelial tissue injury.

Wang H, Asavaroengchai W, Yeap BY, Wang MG, Wang S, Sykes M, Yang YG.

Blood. 2009 Apr 9;113(15):3612-9. Epub 2009 Feb 10.PMID: 19211507 [PubMed - indexed for MEDLINE]Related articles

Hematopoietic cell transplantation for tolerance induction: animal models to clinical trials.

Sykes M.

Transplantation. 2009 Feb 15;87(3):309-16. Review.PMID: 19202432 [PubMed - indexed for MEDLINE]Related articles

Determination of the phenoxyacid herbicides MCPA, mecoprop and 2,4-D in kidney tissue using liquid chromatography with electrospray tandem mass spectrometry.

Charlton AJ, Stuckey V, Sykes MD.

Bull Environ Contam Toxicol. 2009 Jun;82(6):711-5. Epub 2009 Jan 28.PMID: 19183823 [PubMed - indexed for MEDLINE]Related articles

CTLA-4 on alloreactive CD4 T cells interacts with recipient CD80/86 to promote tolerance.

Kurtz J, Raval F, Vallot C, Der J, Sykes M.

Blood. 2009 Apr 9;113(15):3475-84. Epub 2009 Jan 29.PMID: 19179471 [PubMed - indexed for MEDLINE]Related articles

High antigen levels do not preclude B-cell tolerance induction to alpha1,3-Gal via mixed chimerism.

Haspot F, Bardwell PD, Zhao G, Sykes M.

Xenotransplantation. 2008 Sep;15(5):313-20.PMID: 19134161 [PubMed - indexed for MEDLINE]Related articlesFree article

Low magnitude and high frequency mechanical loading prevents decreased bone formation responses of 2T3 preosteoblasts.

Patel MJ, Chang KH, Sykes MC, Talish R, Rubin C, Jo H.

J Cell Biochem. 2009 Feb 1;106(2):306-16.PMID: 19125415 [PubMed - indexed for MEDLINE]Related articlesFree article

Kinetics membrane disruption due to drug interactions of chlorpromazine hydrochloride.

Nussio MR, Sykes MJ, Miners JO, Shapter JG.

Langmuir. 2009 Jan 20;25(2):1086-90.PMID: 19093750 [PubMed - indexed for MEDLINE]Related articles

Achieving tolerance in pig-to-primate xenotransplantation: reality or fantasy.

Sachs DH, Sykes M, Yamada K.

Transpl Immunol. 2009 Jun;21(2):101-5. Epub 2008 Dec 6.PMID: 19059481 [PubMed - in process]Related articles

Abnormal regulatory and effector T cell function predispose to autoimmunity following xenogeneic thymic transplantation.

Fudaba Y, Onoe T, Chittenden M, Shimizu A, Shaffer JM, Bronson R, Sykes M.

J Immunol. 2008 Dec 1;181(11):7649-59.PMID: 19017953 [PubMed - indexed for MEDLINE]Related articles

The host environment regulates the function of CD8+ graft-versus-host-reactive effector cells.

Chakraverty R, Flutter B, Fallah-Arani F, Eom HS, Means T, Andreola G, Schwarte S, Buchli J, Cotter P, Zhao G, Sykes M.

J Immunol. 2008 Nov 15;181(10):6820-8.PMID: 18981100 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical experience with mixed chimerism to induce transplantation tolerance.

Fehr T, Sykes M.

Transpl Int. 2008 Dec;21(12):1118-35. Epub 2008 Oct 23. Review.PMID: 18954364 [PubMed - indexed for MEDLINE]Related articles

Envelope: interactive software for modeling and fitting complex isotope distributions.

Sykes MT, Williamson JR.

BMC Bioinformatics. 2008 Oct 20;9:446.PMID: 18937869 [PubMed - indexed for MEDLINE]Related articlesFree article

Murine mobilized peripheral blood stem cells have a lower capacity than bone marrow to induce mixed chimerism and tolerance.

Koporc Z, Pilat N, Nierlich P, Blaha P, Bigenzahn S, Pree I, Selzer E, Sykes M, Muehlbacher F, Wekerle T.

Am J Transplant. 2008 Oct;8(10):2025-36.PMID: 18828766 [PubMed - indexed for MEDLINE]Related articles

Rapid deletional peripheral CD8 T cell tolerance induced by allogeneic bone marrow: role of donor class II MHC and B cells.

Fehr T, Wang S, Haspot F, Kurtz J, Blaha P, Hogan T, Chittenden M, Wekerle T, Sykes M.

J Immunol. 2008 Sep 15;181(6):4371-80.PMID: 18768896 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of human T cell repertoire generated in xenogeneic porcine and human thymus grafts.

Shimizu I, Fudaba Y, Shimizu A, Yang YG, Sykes M.

Transplantation. 2008 Aug 27;86(4):601-10.PMID: 18724231 [PubMed - indexed for MEDLINE]Related articlesFree article

Response to 'Tolerance versus immunosuppression: a perspective'.

Sachs DH, Kawai T, Colvin RB, Fishman JA, Sykes M, Cosimi AB.

Am J Transplant. 2008 Aug;8(8):1573-4. No abstract available. PMID: 18694470 [PubMed - indexed for MEDLINE]Related articles

Incorporating the effects of changes in vegetation functioning and CO2 on water availability in plant habitat models.

Rickebusch S, Thuiller W, Hickler T, Arau Jo MB, Sykes MT, Schweiger O, Lafourcade B.

Biol Lett. 2008 Oct 23;4(5):556-9.PMID: 18664420 [PubMed - indexed for MEDLINE]Related articlesFree article

Exporting the ecological effects of climate change. Developed and developing countries will suffer the consequences of climate change, but differ in both their responsibility and how badly it will affect their ecosystems.

Thomas CD, Ohlemüller R, Anderson B, Hickler T, Miller PA, Sykes MT, Williams JW.

EMBO Rep. 2008 Jul;9 Suppl 1:S28-33. No abstract available. PMID: 18578020 [PubMed - indexed for MEDLINE]Related articlesFree article

Manipulating the immune system for anti-tumor responses and transplant tolerance via mixed hematopoietic chimerism.

Gibbons C, Sykes M.

Immunol Rev. 2008 Jun;223:334-60. Review.PMID: 18613846 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical outcomes of late rather than early full-donor chimerism in patients with advanced lymphomas receiving nonmyeloablative allogeneic hematopoietic SCT.

Ting DT, Spitzer TR, Chaudhary A, Muzikansky A, Colby C, Power K, McAfee S, Ballen K, Attar E, Saidman SL, Preffer F, Sykes M, Dey BR.

Bone Marrow Transplant. 2008 Sep;42(5):329-35. Epub 2008 Jun 30.PMID: 18587439 [PubMed - indexed for MEDLINE]Related articles

Central tolerance to myogenic cell transplants does not include muscle neoantigens.

Camirand G, Stéphan L, Rousseau J, Sackett MK, Caron NJ, Mills P, Kurtz J, Sykes M, Rothstein DM, Tremblay JP.

Transplantation. 2008 Jun 27;85(12):1791-801.PMID: 18580473 [PubMed - indexed for MEDLINE]Related articles

Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway.

Haspot F, Fehr T, Gibbons C, Zhao G, Hogan T, Honjo T, Freeman GJ, Sykes M.

Blood. 2008 Sep 1;112(5):2149-55. Epub 2008 Jun 24.PMID: 18577709 [PubMed - indexed for MEDLINE]Related articlesFree article

Alloreactive CD8 T cell tolerance requires recipient B cells, dendritic cells, and MHC class II.

Fehr T, Haspot F, Mollov J, Chittenden M, Hogan T, Sykes M.

J Immunol. 2008 Jul 1;181(1):165-73.PMID: 18566381 [PubMed - indexed for MEDLINE]Related articlesFree article

Quantitative analysis of isotope distributions in proteomic mass spectrometry using least-squares Fourier transform convolution.

Sperling E, Bunner AE, Sykes MT, Williamson JR.

Anal Chem. 2008 Jul 1;80(13):4906-17. Epub 2008 Jun 4.PMID: 18522437 [PubMed - indexed for MEDLINE]Related articlesFree article

Method to screen for the addition of porcine blood-based binding products to foods using liquid chromatography/triple quadrupole mass spectrometry.

Grundy HH, Reece P, Sykes MD, Clough JA, Audsley N, Stones R.

Rapid Commun Mass Spectrom. 2008 Jun;22(12):2006-8. No abstract available. PMID: 18493905 [PubMed - indexed for MEDLINE]Related articles

CD134-allodepletion allows selective elimination of alloreactive human T cells without loss of virus-specific and leukemia-specific effectors.

Ge X, Brown J, Sykes M, Boussiotis VA.

Biol Blood Marrow Transplant. 2008 May;14(5):518-30.PMID: 18410894 [PubMed - indexed for MEDLINE]Related articlesFree article

The first Joint Conference of the Cell Transplant Society (CTS), International Pancreas and Islet Transplant Association (IPITA), and International Xenotransplantation Association (IXA), all sections of The Transplantation Society (TTS), took place in Minneapolis, Minn, USA, from September 15-20, 2007. Preface.

Hering BJ, Sykes M, Sutherland DE, Shapiro AM, Tremblay JP.

Transplant Proc. 2008 Mar;40(2):335-6. No abstract available. PMID: 18374060 [PubMed - indexed for MEDLINE]Related articles

Planetary science. The planet debate continues.

Sykes MV.

Science. 2008 Mar 28;319(5871):1765. No abstract available. PMID: 18369125 [PubMed]Related articles

My most interesting cases.

Kawai T, Sachs DH, Sykes M, Spitzer T, Tolkoff-Rubin N, Saidman S, Ko D, Dey B, Colvin RB, Cosimi AB.

Clin Transpl. 2006:580-2. No abstract available. PMID: 18365443 [PubMed - indexed for MEDLINE]Related articles

2007 IXA Presidential Address. Progress toward an ideal source animal: opportunities and challenges in a changing world.

Sykes M.

Xenotransplantation. 2008 Feb;15(1):7-13.PMID: 18333908 [PubMed - indexed for MEDLINE]Related articles

Antigen-specific human T-cell responses and T cell-dependent production of human antibodies in a humanized mouse model.

Tonomura N, Habiro K, Shimizu A, Sykes M, Yang YG.

Blood. 2008 Apr 15;111(8):4293-6. Epub 2008 Feb 12.PMID: 18270327 [PubMed - indexed for MEDLINE]Related articlesFree article

Prediction of metabolism by cytochrome P450 2C9: alignment and docking studies of a validated database of substrates.

Sykes MJ, McKinnon RA, Miners JO.

J Med Chem. 2008 Feb 28;51(4):780-91. Epub 2008 Feb 1.PMID: 18237107 [PubMed - indexed for MEDLINE]Related articles

Lysianadioic acid, a carboxypeptidase B inhibitor from Lysiana subfalcata.

Buchanan MS, Carroll AR, Edser A, Sykes M, Fechner GA, Forster PI, Guymer GP, Quinn RJ.

Bioorg Med Chem Lett. 2008 Feb 15;18(4):1495-7. Epub 2007 Dec 25.PMID: 18222087 [PubMed - indexed for MEDLINE]Related articles

HLA-mismatched renal transplantation without maintenance immunosuppression.

Kawai T, Cosimi AB, Spitzer TR, Tolkoff-Rubin N, Suthanthiran M, Saidman SL, Shaffer J, Preffer FI, Ding R, Sharma V, Fishman JA, Dey B, Ko DS, Hertl M, Goes NB, Wong W, Williams WW Jr, Colvin RB, Sykes M, Sachs DH.

N Engl J Med. 2008 Jan 24;358(4):353-61.PMID: 18216355 [PubMed - indexed for MEDLINE]Related articlesFree article

The Gaussian Generalized Born model: application to small molecules.

Grant JA, Pickup BT, Sykes MJ, Kitchen CA, Nicholls A.

Phys Chem Chem Phys. 2007 Sep 21;9(35):4913-22. Epub 2007 Jul 17.PMID: 17912422 [PubMed]Related articles

Medical students and refugee doctors: learning together.

Anderson K, Sykes M, Fisher P.

Med Educ. 2007 Nov;41(11):1105-6. Epub 2007 Sep 19. No abstract available. PMID: 17883380 [PubMed - indexed for MEDLINE]Related articles

Porcine thymic grafts protect human thymocytes from HIV-1-induced destruction.

Hongo D, Hadidi S, Damrauer S, Garrigue V, Kraft D, Sachs DH, Nikolic B, Sykes M.

J Infect Dis. 2007 Sep 15;196(6):900-10. Epub 2007 Aug 7.PMID: 17703422 [PubMed - indexed for MEDLINE]Related articles