PubMed

The interaction of insulin-like growth factor binding protein-3 and bax in mitochondria promotes male germ cell apoptosis.

Jia Y, Lee KW, Swerdloff RS, Hwang D, Cobb LJ, Sinha Hikim A, Lue YH, Cohen P, Wang C.

J Biol Chem. 2009 Nov 3. [Epub ahead of print]PMID: 19887447 [PubMed - as supplied by publisher]Related articlesFree article

Transplanted XY germ cells produce spermatozoa in testes of XXY mice*

Lue Y, Liu PY, Erkkila K, Ma K, Schwarcz M, Wang C, Swerdloff RS.

Int J Androl. 2009 Jul 20. [Epub ahead of print]PMID: 19622086 [PubMed - as supplied by publisher]Related articles

Kinetic and thermodynamic characterization of dihydrotestosterone-induced conformational perturbations in androgen receptor ligand-binding domain.

Jasuja R, Ulloor J, Yengo CM, Choong K, Istomin AY, Livesay DR, Jacobs DJ, Swerdloff RS, Miksovská J, Larsen RW, Bhasin S.

Mol Endocrinol. 2009 Aug;23(8):1231-41. Epub 2009 May 14.PMID: 19443608 [PubMed - in process]Related articles

Combined transdermal testosterone gel and the progestin nestorone suppresses serum gonadotropins in men.

Mahabadi V, Amory JK, Swerdloff RS, Bremner WJ, Page ST, Sitruk-Ware R, Christensen PD, Kumar N, Tsong YY, Blithe D, Wang C.

J Clin Endocrinol Metab. 2009 Jul;94(7):2313-20. Epub 2009 Apr 14.PMID: 19366848 [PubMed - indexed for MEDLINE]Related articles

Mitogen-activated protein kinase signaling in male germ cell apoptosis in the rat.

Jia Y, Castellanos J, Wang C, Sinha-Hikim I, Lue Y, Swerdloff RS, Sinha-Hikim AP.

Biol Reprod. 2009 Apr;80(4):771-80. Epub 2008 Dec 23. Erratum in: Biol Reprod. 2009 Jun;80(6):1308. PMID: 19109224 [PubMed - indexed for MEDLINE]Related articles

Levonorgestrel enhances spermatogenesis suppression by testosterone with greater alteration in testicular gene expression in men.

Lue Y, Wang C, Cui Y, Wang X, Sha J, Zhou Z, Xu J, Wang C, Hikim AP, Swerdloff RS.

Biol Reprod. 2009 Mar;80(3):484-92. Epub 2008 Dec 10.PMID: 19074003 [PubMed - indexed for MEDLINE]Related articles

Pituitary hormonal loss and recovery after transsphenoidal adenoma removal.

Fatemi N, Dusick JR, Mattozo C, McArthur DL, Cohan P, Boscardin J, Wang C, Swerdloff RS, Kelly DF.

Neurosurgery. 2008 Oct;63(4):709-18; discussion 718-9.PMID: 18981881 [PubMed - indexed for MEDLINE]Related articles

Long acting testosterone undecanoate therapy in men with hypogonadism: results of a pharmacokinetic clinical study.

Morgentaler A, Dobs AS, Kaufman JM, Miner MM, Shabsigh R, Swerdloff RS, Wang C.

J Urol. 2008 Dec;180(6):2307-13. Epub 2008 Oct 18.PMID: 18930255 [PubMed - indexed for MEDLINE]Related articles

Obesity, low testosterone levels and erectile dysfunction.

Diaz-Arjonilla M, Schwarcz M, Swerdloff RS, Wang C.

Int J Impot Res. 2009 Mar-Apr;21(2):89-98. Epub 2008 Oct 9. Review.PMID: 18843273 [PubMed - indexed for MEDLINE]Related articles

Expression of nitric oxide synthase during germ cell apoptosis in testis of cynomolgus monkey after testosterone and heat treatment.

Guo J, Jia Y, Tao SX, Li YC, Zhang XS, Hu ZY, Chiang N, Lue YH, Hikim AP, Swerdloff RS, Wang C, Liu YX.

J Androl. 2009 Mar-Apr;30(2):190-9. Epub 2008 Oct 2.PMID: 18835830 [PubMed - indexed for MEDLINE]Related articles

Simultaneous measurement of serum testosterone and dihydrotestosterone by liquid chromatography-tandem mass spectrometry.

Shiraishi S, Lee PW, Leung A, Goh VH, Swerdloff RS, Wang C.

Clin Chem. 2008 Nov;54(11):1855-63. Epub 2008 Sep 18.PMID: 18801940 [PubMed - indexed for MEDLINE]Related articlesFree article

ISA, ISSAM, EAU, EAA and ASA recommendations: investigation, treatment and monitoring of late-onset hypogonadism in males.

Wang C, Nieschlag E, Swerdloff RS, Behre H, Hellstrom WJ, Gooren LJ, Kaufman JM, Legros JJ, Lunenfeld B, Morales A, Morley JE, Schulman C, Thompson IM, Weidner W, Wu FC.

Aging Male. 2009 Mar;12(1):5-12. No abstract available. PMID: 18763169 [PubMed - indexed for MEDLINE]Related articles

Proteomic analysis of testis biopsies in men treated with injectable testosterone undecanoate alone or in combination with oral levonorgestrel as potential male contraceptive.

Cui Y, Zhu H, Zhu Y, Guo X, Huo R, Wang X, Tong J, Qian L, Zhou Z, Jia Y, Lue YH, Hikim AS, Wang C, Swerdloff RS, Sha J.

J Proteome Res. 2008 Sep;7(9):3984-93. Epub 2008 Aug 15.PMID: 18702538 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of caspase 2 in apoptotic signaling in primate and murine germ cells.

Johnson C, Jia Y, Wang C, Lue YH, Swerdloff RS, Zhang XS, Hu ZY, Li YC, Liu YX, Hikim AP.

Biol Reprod. 2008 Nov;79(5):806-14. Epub 2008 Jul 9.PMID: 18614702 [PubMed - indexed for MEDLINE]Related articlesFree article

Validation of a testosterone and dihydrotestosterone liquid chromatography tandem mass spectrometry assay: Interference and comparison with established methods.

Wang C, Shiraishi S, Leung A, Baravarian S, Hull L, Goh V, Lee PW, Swerdloff RS.

Steroids. 2008 Dec 12;73(13):1345-52. Epub 2008 May 21.PMID: 18579171 [PubMed - indexed for MEDLINE]Related articlesFree article

Pituitary function after endonasal surgery for nonadenomatous parasellar tumors: Rathke's cleft cysts, craniopharyngiomas, and meningiomas.

Dusick JR, Fatemi N, Mattozo C, McArthur D, Cohan P, Wang C, Swerdloff RS, Kelly DF.

Surg Neurol. 2008 Nov;70(5):482-90; discussion 490-1. Epub 2008 May 14.PMID: 18482750 [PubMed - indexed for MEDLINE]Related articles

The effect of 5alpha-reductase inhibition with dutasteride and finasteride on bone mineral density, serum lipoproteins, hemoglobin, prostate specific antigen and sexual function in healthy young men.

Amory JK, Anawalt BD, Matsumoto AM, Page ST, Bremner WJ, Wang C, Swerdloff RS, Clark RV.

J Urol. 2008 Jun;179(6):2333-8. Epub 2008 Apr 18.PMID: 18423697 [PubMed - indexed for MEDLINE]Related articlesFree article

Should hypogonadal men who are suboptimally responsive to testosterone gel switch to another gel preparation?

Swerdloff RS.

Nat Clin Pract Urol. 2008 Apr;5(4):190-1. Epub 2008 Mar 4. No abstract available. PMID: 18317495 [PubMed]Related articles

Free testosterone measurement by the analog displacement direct assay: old concerns and new evidence.

Swerdloff RS, Wang C.

Clin Chem. 2008 Mar;54(3):458-60. No abstract available. PMID: 18310144 [PubMed - indexed for MEDLINE]Related articlesFree article

Determinants of the rate and extent of spermatogenic suppression during hormonal male contraception: an integrated analysis.

Liu PY, Swerdloff RS, Anawalt BD, Anderson RA, Bremner WJ, Elliesen J, Gu YQ, Kersemaekers WM, McLachlan RI, Meriggiola MC, Nieschlag E, Sitruk-Ware R, Vogelsong K, Wang XH, Wu FC, Zitzmann M, Handelsman DJ, Wang C.

J Clin Endocrinol Metab. 2008 May;93(5):1774-83. Epub 2008 Feb 26.PMID: 18303073 [PubMed - indexed for MEDLINE]Related articlesFree article

transient scrotal hyperthermia and levonorgestrel enhance testosterone-induced spermatogenesis suppression in men through increased germ cell apoptosis.

Wang C, Cui YG, Wang XH, Jia Y, Sinha Hikim A, Lue YH, Tong JS, Qian LX, Sha JH, Zhou ZM, Hull L, Leung A, Swerdloff RS.

J Clin Endocrinol Metab. 2007 Aug;92(8):3292-304. Epub 2007 May 15.PMID: 17504903 [PubMed - indexed for MEDLINE]Related articlesFree article

Testosterone treatment in multiple sclerosis: a pilot study.

Sicotte NL, Giesser BS, Tandon V, Klutch R, Steiner B, Drain AE, Shattuck DW, Hull L, Wang HJ, Elashoff RM, Swerdloff RS, Voskuhl RR.

Arch Neurol. 2007 May;64(5):683-8.PMID: 17502467 [PubMed - indexed for MEDLINE]Related articlesFree article

Signaling pathways for germ cell death in adult cynomolgus monkeys (Macaca fascicularis) induced by mild testicular hyperthermia and exogenous testosterone treatment.

Jia Y, Hikim AP, Lue YH, Swerdloff RS, Vera Y, Zhang XS, Hu ZY, Li YC, Liu YX, Wang C.

Biol Reprod. 2007 Jul;77(1):83-92. Epub 2007 Mar 21.PMID: 17377139 [PubMed - indexed for MEDLINE]Related articlesFree article

Fate of bone marrow stem cells transplanted into the testis: potential implication for men with testicular failure.

Lue Y, Erkkila K, Liu PY, Ma K, Wang C, Hikim AS, Swerdloff RS.

Am J Pathol. 2007 Mar;170(3):899-908.PMID: 17322375 [PubMed - indexed for MEDLINE]Related articlesFree article

The effect of 5alpha-reductase inhibition with dutasteride and finasteride on semen parameters and serum hormones in healthy men.

Amory JK, Wang C, Swerdloff RS, Anawalt BD, Matsumoto AM, Bremner WJ, Walker SE, Haberer LJ, Clark RV.

J Clin Endocrinol Metab. 2007 May;92(5):1659-65. Epub 2007 Feb 13. Erratum in: J Clin Endocrinol Metab. 2007 Nov;92(11):4379. PMID: 17299062 [PubMed - indexed for MEDLINE]Related articlesFree article

Does individual response to androgen replacement therapy affect bone density?

Liu PY, Wang C, Swerdloff RS.

Nat Clin Pract Endocrinol Metab. 2006 Feb;2(2):76-7. No abstract available. PMID: 16932260 [PubMed - indexed for MEDLINE]Related articles

Pharmacokinetics of testosterone undecanoate injected alone or in combination with norethisterone enanthate in healthy men.

Qoubaitary A, Meriggiola C, Ng CM, Lumbreras L, Cerpolini S, Pelusi G, Christensen PD, Hull L, Swerdloff RS, Wang C.

J Androl. 2006 Nov-Dec;27(6):853-67. Epub 2006 Jul 12.PMID: 16837736 [PubMed - indexed for MEDLINE]Related articlesFree article

Testosterone therapy in adult men with androgen deficiency syndromes: an endocrine society clinical practice guideline.

Bhasin S, Cunningham GR, Hayes FJ, Matsumoto AM, Snyder PJ, Swerdloff RS, Montori VM.

J Clin Endocrinol Metab. 2006 Jun;91(6):1995-2010. Epub 2006 May 23. Erratum in: J Clin Endocrinol Metab. 2006 Jul;91(7):2688. PMID: 16720669 [PubMed - indexed for MEDLINE]Related articlesFree article

Rate, extent, and modifiers of spermatogenic recovery after hormonal male contraception: an integrated analysis.

Liu PY, Swerdloff RS, Christenson PD, Handelsman DJ, Wang C; Hormonal Male Contraception Summit Group.

Lancet. 2006 Apr 29;367(9520):1412-20.PMID: 16650651 [PubMed - indexed for MEDLINE]Related articles

Involvement of p38 mitogen-activated protein kinase and inducible nitric oxide synthase in apoptotic signaling of murine and human male germ cells after hormone deprivation.

Vera Y, Erkkilä K, Wang C, Nunez C, Kyttänen S, Lue Y, Dunkel L, Swerdloff RS, Sinha Hikim AP.

Mol Endocrinol. 2006 Jul;20(7):1597-609. Epub 2006 Feb 9.PMID: 16469770 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of orphan receptors TR2, TR3, TR4, and p53 in heat-treated testis of cynomolgus monkeys (Macaca fascicularis).

Zhang XS, Yuan JX, Liu T, Lue YH, Jin X, Tao SX, Hu ZY, Hikim AP, Swerdloff RS, Wang C, Liu YX.

J Androl. 2006 May-Jun;27(3):405-13. Epub 2006 Feb 1.PMID: 16452526 [PubMed - indexed for MEDLINE]Related articlesFree article

The structural brain correlates of cognitive deficits in adults with Klinefelter's syndrome.

Itti E, Gaw Gonzalo IT, Pawlikowska-Haddal A, Boone KB, Mlikotic A, Itti L, Mishkin FS, Swerdloff RS.

J Clin Endocrinol Metab. 2006 Apr;91(4):1423-7. Epub 2006 Jan 10.PMID: 16403821 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of human male germ cell death by modulators of ATP production.

Erkkila K, Kyttanen S, Wikstrom M, Taari K, Hikim AP, Swerdloff RS, Dunkel L.

Am J Physiol Endocrinol Metab. 2006 Jun;290(6):E1145-54. Epub 2006 Jan 10.PMID: 16403780 [PubMed - indexed for MEDLINE]Related articlesFree article

Male sex matters.

Liu PY, Wang C, Swerdloff RS.

Clin Endocrinol (Oxf). 2005 Dec;63(6):601-2. No abstract available. PMID: 16343092 [PubMed - indexed for MEDLINE]Related articles

Dedifferentiation of adult monkey Sertoli cells through activation of extracellularly regulated kinase 1/2 induced by heat treatment.

Zhang XS, Zhang ZH, Jin X, Wei P, Hu XQ, Chen M, Lu CL, Lue YH, Hu ZY, Sinha Hikim AP, Swerdloff RS, Wang C, Liu YX.

Endocrinology. 2006 Mar;147(3):1237-45. Epub 2005 Dec 8.PMID: 16339203 [PubMed - indexed for MEDLINE]Related articlesFree article

Transient testicular warming enhances the suppressive effect of testosterone on spermatogenesis in adult cynomolgus monkeys (Macaca fascicularis).

Lue Y, Wang C, Liu YX, Hikim AP, Zhang XS, Ng CM, Hu ZY, Li YC, Leung A, Swerdloff RS.

J Clin Endocrinol Metab. 2006 Feb;91(2):539-45. Epub 2005 Nov 29.PMID: 16317056 [PubMed - indexed for MEDLINE]Related articlesFree article

Mouse model of male germ cell apoptosis in response to a lack of hormonal stimulation.

Hikim AP, Vera Y, Elhag RI, Lue Y, Cui YG, Pope V, Leung A, Atienza V, Wang C, Swerdloff RS.

Indian J Exp Biol. 2005 Nov;43(11):1048-57.PMID: 16315394 [PubMed - indexed for MEDLINE]Related articles

Relative testosterone deficiency in older men: clinical definition and presentation.

Liu PY, Swerdloff RS, Wang C.

Endocrinol Metab Clin North Am. 2005 Dec;34(4):957-72, x. Review. No abstract available. PMID: 16310633 [PubMed - indexed for MEDLINE]Related articles

Androgen deficiency in the etiology and treatment of erectile dysfunction.

Gore JL, Swerdloff RS, Rajfer J.

Urol Clin North Am. 2005 Nov;32(4):457-68, vi-vii. Review.PMID: 16291037 [PubMed - indexed for MEDLINE]Related articles

Levonorgestrel implants enhanced the suppression of spermatogenesis by testosterone implants: comparison between Chinese and non-Chinese men.

Wang C, Wang XH, Nelson AL, Lee KK, Cui YG, Tong JS, Berman N, Lumbreras L, Leung A, Hull L, Desai S, Swerdloff RS.

J Clin Endocrinol Metab. 2006 Feb;91(2):460-70. Epub 2005 Nov 8.PMID: 16278260 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical review: Early morning cortisol levels as a predictor of remission after transsphenoidal surgery for Cushing's disease.

Esposito F, Dusick JR, Cohan P, Moftakhar P, McArthur D, Wang C, Swerdloff RS, Kelly DF.

J Clin Endocrinol Metab. 2006 Jan;91(1):7-13. Epub 2005 Oct 18.PMID: 16234305 [PubMed - indexed for MEDLINE]Related articlesFree article

Minocycline up-regulates BCL-2 levels in mitochondria and attenuates male germ cell apoptosis.

Castanares M, Vera Y, Erkkilä K, Kyttänen S, Lue Y, Dunkel L, Wang C, Swerdloff RS, Hikim AP.

Biochem Biophys Res Commun. 2005 Nov 18;337(2):663-9. Epub 2005 Sep 26.PMID: 16202388 [PubMed - indexed for MEDLINE]Related articles

Advances in male hormone substitution therapy.

Qoubaitary A, Swerdloff RS, Wang C.

Expert Opin Pharmacother. 2005 Aug;6(9):1493-506. Review.PMID: 16086637 [PubMed - indexed for MEDLINE]Related articles

Unusual occurrence of extrapontine myelinolysis associated with acute severe hypernatraemia caused by central diabetes insipidus.

Chang L, Harrington DW, Milkotic A, Swerdloff RS, Wang C.

Clin Endocrinol (Oxf). 2005 Aug;63(2):233-5. No abstract available. PMID: 16060921 [PubMed - indexed for MEDLINE]Related articles

Transdermal androgens: pharmacology and applicability to hypogonadal elderly men.

Swerdloff RS, Wang C.

J Endocrinol Invest. 2005;28(3 Suppl):112-6. Review.PMID: 16042369 [PubMed - indexed for MEDLINE]Related articles

Pratical aspects of testosterone substitution.

Wang C, Swerdloff RS.

J Endocrinol Invest. 2005;28(3 Suppl):109-11. Review.PMID: 16042368 [PubMed - indexed for MEDLINE]Related articles

Involvement of nitric oxide-mediated intrinsic pathway signaling in age-related increase in germ cell apoptosis in male Brown-Norway rats.

Hikim AP, Vera Y, Vernet D, Castanares M, Diaz-Romero M, Ferrini M, Swerdloff RS, Gonzalez-Cadavid NF, Wang C.

J Gerontol A Biol Sci Med Sci. 2005 Jun;60(6):702-8.PMID: 15983171 [PubMed - indexed for MEDLINE]Related articles

Expression of HSP105 and HSP60 during germ cell apoptosis in the heat-treated testes of adult cynomolgus monkeys (macaca fascicularis).

Zhang XS, Lue YH, Guo SH, Yuan JX, Hu ZY, Han CS, Hikim AP, Swerdloff RS, Wang C, Liu YX.

Front Biosci. 2005 Sep 1;10:3110-21. Review.PMID: 15970565 [PubMed - indexed for MEDLINE]Related articles

XXY mice exhibit gonadal and behavioral phenotypes similar to Klinefelter syndrome.

Lue Y, Jentsch JD, Wang C, Rao PN, Hikim AP, Salameh W, Swerdloff RS.

Endocrinology. 2005 Sep;146(9):4148-54. Epub 2005 Jun 16.PMID: 15961558 [PubMed - indexed for MEDLINE]Related articlesFree article

Low-fat high-fiber diet decreased serum and urine androgens in men.

Wang C, Catlin DH, Starcevic B, Heber D, Ambler C, Berman N, Lucas G, Leung A, Schramm K, Lee PW, Hull L, Swerdloff RS.

J Clin Endocrinol Metab. 2005 Jun;90(6):3550-9. Epub 2005 Mar 1.PMID: 15741266 [PubMed - indexed for MEDLINE]Related articlesFree article