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    Results: 28

    1.

    GABAergic Differentiation Induced by Mash1 Is Compromised by the bHLH Proteins Neurogenin2, NeuroD1, and NeuroD2.

    Roybon L, Mastracci TL, Ribeiro D, Sussel L, Brundin P, Li JY.

    Cereb Cortex. 2009 Sep 18. [Epub ahead of print]PMID: 19767311 [PubMed - as supplied by publisher]Related articles

    2.

    Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3.

    Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L.

    J Biol Chem. 2009 Nov 6;284(45):31236-48. Epub 2009 Sep 15.PMID: 19759004 [PubMed - in process]Related articles

    3.

    Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain.

    Prakash N, Puelles E, Freude K, Trümbach D, Omodei D, Di Salvio M, Sussel L, Ericson J, Sander M, Simeone A, Wurst W.

    Development. 2009 Aug;136(15):2545-55.PMID: 19592574 [PubMed - indexed for MEDLINE]Related articles

    4.

    Ghrelin is dispensable for embryonic pancreatic islet development and differentiation.

    Hill JT, Mastracci TL, Vinton C, Doyle ML, Anderson KR, Loomis ZL, Schrunk JM, Minic AD, Prabakar KR, Pugliese A, Sun Y, Smith RG, Sussel L.

    Regul Pept. 2009 Oct 9;157(1-3):51-6. Epub 2009 Mar 5.PMID: 19268691 [PubMed - in process]Related articles

    5.

    Ets transcription factors control epithelial maturation and transit and crypt-villus morphogenesis in the mammalian intestine.

    Jedlicka P, Sui X, Sussel L, Gutierrez-Hartmann A.

    Am J Pathol. 2009 Apr;174(4):1280-90. Epub 2009 Mar 5.PMID: 19264912 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Nkx2.2 regulates cell fate choice in the enteroendocrine cell lineages of the intestine.

    Desai S, Loomis Z, Pugh-Bernard A, Schrunk J, Doyle MJ, Minic A, McCoy E, Sussel L.

    Dev Biol. 2008 Jan 1;313(1):58-66. Epub 2007 Oct 3.PMID: 18022152 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells.

    Chao CS, Loomis ZL, Lee JE, Sussel L.

    Dev Biol. 2007 Dec 15;312(2):523-32. Epub 2007 Oct 5.PMID: 17988662 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Nkx2.2 regulates beta-cell function in the mature islet.

    Doyle MJ, Sussel L.

    Diabetes. 2007 Aug;56(8):1999-2007. Epub 2007 Apr 24.PMID: 17456846 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet.

    Doyle MJ, Loomis ZL, Sussel L.

    Development. 2007 Feb;134(3):515-23. Epub 2007 Jan 3.PMID: 17202186 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Gata6 is an important regulator of mouse pancreas development.

    Decker K, Goldman DC, Grasch CL, Sussel L.

    Dev Biol. 2006 Oct 15;298(2):415-29. Epub 2006 Jul 4.PMID: 16887115 [PubMed - indexed for MEDLINE]Related articles

    11.

    FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site.

    Raum JC, Gerrish K, Artner I, Henderson E, Guo M, Sussel L, Schisler JC, Newgard CB, Stein R.

    Mol Cell Biol. 2006 Aug;26(15):5735-43.PMID: 16847327 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo.

    Prakash N, Brodski C, Naserke T, Puelles E, Gogoi R, Hall A, Panhuysen M, Echevarria D, Sussel L, Weisenhorn DM, Martinez S, Arenas E, Simeone A, Wurst W.

    Development. 2006 Jan;133(1):89-98.PMID: 16339193 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Engineering islets: lessons from stem cells and embryonic development.

    Doyle MJ, Sussel L.

    Endocrinol Metab Clin North Am. 2004 Mar;33(1):149-62, x. Review. No abstract available. PMID: 15053900 [PubMed - indexed for MEDLINE]Related articles

    14.

    Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development.

    Prado CL, Pugh-Bernard AE, Elghazi L, Sosa-Pineda B, Sussel L.

    Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2924-9. Epub 2004 Feb 17.PMID: 14970313 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    The concerted activities of Pax4 and Nkx2.2 are essential to initiate pancreatic beta-cell differentiation.

    Wang J, Elghazi L, Parker SE, Kizilocak H, Asano M, Sussel L, Sosa-Pineda B.

    Dev Biol. 2004 Feb 1;266(1):178-89.PMID: 14729487 [PubMed - indexed for MEDLINE]Related articles

    16.

    Transcription factor occupancy of the insulin gene in vivo. Evidence for direct regulation by Nkx2.2.

    Cissell MA, Zhao L, Sussel L, Henderson E, Stein R.

    J Biol Chem. 2003 Jan 10;278(2):751-6. Epub 2002 Nov 7.PMID: 12426319 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Control of oligodendrocyte differentiation by the Nkx2.2 homeodomain transcription factor.

    Qi Y, Cai J, Wu Y, Wu R, Lee J, Fu H, Rao M, Sussel L, Rubenstein J, Qiu M.

    Development. 2001 Jul;128(14):2723-33.PMID: 11526078 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas.

    Sander M, Sussel L, Conners J, Scheel D, Kalamaras J, Dela Cruz F, Schwitzgebel V, Hayes-Jordan A, German M.

    Development. 2000 Dec;127(24):5533-40.PMID: 11076772 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Expression of neurogenin3 reveals an islet cell precursor population in the pancreas.

    Schwitzgebel VM, Scheel DW, Conners JR, Kalamaras J, Lee JE, Anderson DJ, Sussel L, Johnson JD, German MS.

    Development. 2000 Aug;127(16):3533-42.PMID: 10903178 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Loss of Nkx2.1 homeobox gene function results in a ventral to dorsal molecular respecification within the basal telencephalon: evidence for a transformation of the pallidum into the striatum.

    Sussel L, Marin O, Kimura S, Rubenstein JL.

    Development. 1999 Aug;126(15):3359-70.PMID: 10393115 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling.

    Briscoe J, Sussel L, Serup P, Hartigan-O'Connor D, Jessell TM, Rubenstein JL, Ericson J.

    Nature. 1999 Apr 15;398(6728):622-7.PMID: 10217145 [PubMed - indexed for MEDLINE]Related articles

    22.

    Beta-cell transcription factors and diabetes: mutations in the coding region of the BETA2/NeuroD1 (NEUROD1) and Nkx2.2 (NKX2B) genes are not associated with maturity-onset diabetes of the young in Japanese.

    Furuta H, Horikawa Y, Iwasaki N, Hara M, Sussel L, Le Beau MM, Davis EM, Ogata M, Iwamoto Y, German MS, Bell GI.

    Diabetes. 1998 Aug;47(8):1356-8. No abstract available. PMID: 9703340 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic beta cells.

    Sussel L, Kalamaras J, Hartigan-O'Connor DJ, Meneses JJ, Pedersen RA, Rubenstein JL, German MS.

    Development. 1998 Jun;125(12):2213-21.PMID: 9584121 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    Control of anteroposterior and dorsoventral domains of Nkx-6.1 gene expression relative to other Nkx genes during vertebrate CNS development.

    Qiu M, Shimamura K, Sussel L, Chen S, Rubenstein JL.

    Mech Dev. 1998 Mar;72(1-2):77-88.PMID: 9533954 [PubMed - indexed for MEDLINE]Related articles

    25.

    Suppressors of defective silencing in yeast: effects on transcriptional repression at the HMR locus, cell growth and telomere structure.

    Sussel L, Vannier D, Shore D.

    Genetics. 1995 Nov;141(3):873-88.PMID: 8582633 [PubMed - indexed for MEDLINE]Related articlesFree article

    26.

    Epigenetic switching of transcriptional states: cis- and trans-acting factors affecting establishment of silencing at the HMR locus in Saccharomyces cerevisiae.

    Sussel L, Vannier D, Shore D.

    Mol Cell Biol. 1993 Jul;13(7):3919-28.PMID: 8321199 [PubMed - indexed for MEDLINE]Related articlesFree article

    27.

    A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation.

    Hardy CF, Sussel L, Shore D.

    Genes Dev. 1992 May;6(5):801-14.PMID: 1577274 [PubMed - indexed for MEDLINE]Related articlesFree article

    28.

    Separation of transcriptional activation and silencing functions of the RAP1-encoded repressor/activator protein 1: isolation of viable mutants affecting both silencing and telomere length.

    Sussel L, Shore D.

    Proc Natl Acad Sci U S A. 1991 Sep 1;88(17):7749-53.PMID: 1881914 [PubMed - indexed for MEDLINE]Related articlesFree article

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