PubMed

Th1 and Th17 cells induce proliferative glomerulonephritis.

Summers SA, Steinmetz OM, Li M, Kausman JY, Semple T, Edgtton KL, Borza DB, Braley H, Holdsworth SR, Kitching AR.

J Am Soc Nephrol. 2009 Dec;20(12):2518-24. Epub 2009 Oct 9.PMID: 19820122 [PubMed - in process]Related articles

Lipid oversupply, selective insulin resistance, and lipotoxicity: Molecular mechanisms.

Chavez JA, Summers SA.

Biochim Biophys Acta. 2009 Sep 29. [Epub ahead of print]PMID: 19796706 [PubMed - as supplied by publisher]Related articles

Role of mast cells in progressive renal diseases.

Holdsworth SR, Summers SA.

J Am Soc Nephrol. 2008 Dec;19(12):2254-61. Epub 2008 Sep 5. Review.PMID: 18776124 [PubMed - indexed for MEDLINE]Related articlesFree article

Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice.

Fujii N, Ho RC, Manabe Y, Jessen N, Toyoda T, Holland WL, Summers SA, Hirshman MF, Goodyear LJ.

Diabetes. 2008 Nov;57(11):2958-66. Epub 2008 Aug 26.PMID: 18728234 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute oxalate nephropathy causing late renal transplant dysfunction due to enteric hyperoxaluria.

Rankin AC, Walsh SB, Summers SA, Owen MP, Mansell MA.

Am J Transplant. 2008 Aug;8(8):1755-8. Epub 2008 Jun 28.PMID: 18557738 [PubMed - indexed for MEDLINE]Related articles

Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism.

Holland WL, Summers SA.

Endocr Rev. 2008 Jun;29(4):381-402. Epub 2008 May 1. Review.PMID: 18451260 [PubMed - indexed for MEDLINE]Related articlesFree article

Acute poisoning on the medical admissions unit.

Summers SA, Glynne PA.

Clin Med. 2007 Jun;7(3):277-9. Review. No abstract available. PMID: 17633951 [PubMed - indexed for MEDLINE]Related articles

Lipid mediators of insulin resistance.

Holland WL, Knotts TA, Chavez JA, Wang LP, Hoehn KL, Summers SA.

Nutr Rev. 2007 Jun;65(6 Pt 2):S39-46. Review.PMID: 17605313 [PubMed - indexed for MEDLINE]Related articles

Renal disease and the mouth.

Summers SA, Tilakaratne WM, Fortune F, Ashman N.

Am J Med. 2007 Jul;120(7):568-73. Review.PMID: 17602925 [PubMed - indexed for MEDLINE]Related articles

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance.

Holland WL, Brozinick JT, Wang LP, Hawkins ED, Sargent KM, Liu Y, Narra K, Hoehn KL, Knotts TA, Siesky A, Nelson DH, Karathanasis SK, Fontenot GK, Birnbaum MJ, Summers SA.

Cell Metab. 2007 Mar;5(3):167-79.PMID: 17339025 [PubMed - indexed for MEDLINE]Related articles

Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis.

Arbiser JL, Kau T, Konar M, Narra K, Ramchandran R, Summers SA, Vlahos CJ, Ye K, Perry BN, Matter W, Fischl A, Cook J, Silver PA, Bain J, Cohen P, Whitmire D, Furness S, Govindarajan B, Bowen JP.

Blood. 2007 Jan 15;109(2):560-5. Epub 2006 Sep 21.PMID: 16990598 [PubMed - indexed for MEDLINE]Related articlesFree article

Renal vein thrombosis in a renal allograft.

Summers SA, Partridge W, Laing C, Cook PR.

Br J Hosp Med (Lond). 2006 Aug;67(8):438. No abstract available. PMID: 16918112 [PubMed - indexed for MEDLINE]Related articles

The need to build a strong foundation: a return to the basics.

Summers SA, Laing C, Kelly PA, Marshall D.

Br J Hosp Med (Lond). 2006 Jun;67(6):M106-8. No abstract available. PMID: 16821735 [PubMed - indexed for MEDLINE]Related articles

Ceramides in insulin resistance and lipotoxicity.

Summers SA.

Prog Lipid Res. 2006 Jan;45(1):42-72. Epub 2005 Dec 19. Review.PMID: 16445986 [PubMed - indexed for MEDLINE]Related articles

Haemodialysis catheter-associated infection: common pathogens in unusual places.

Summers SA, Gupta RK, Clutterbuck EJ, Laing C, Cooke GS.

Nephrol Dial Transplant. 2005 Oct;20(10):2287-8. Epub 2005 Jul 26. No abstract available. PMID: 16046503 [PubMed - indexed for MEDLINE]Related articlesFree article

Cure of disseminated cryptococcal infection in a renal allograft recipient after addition of gamma-interferon to anti-fungal therapy.

Summers SA, Dorling A, Boyle JJ, Shaunak S.

Am J Transplant. 2005 Aug;5(8):2067-9.PMID: 15996262 [PubMed - indexed for MEDLINE]Related articles

Is it rejection? Be on the lookout for 'decoys'.

Summers SA, Laing C, Cook TH, Maxwell PH.

Nephrol Dial Transplant. 2005 Sep;20(9):2002-4. Epub 2005 May 26. No abstract available. PMID: 15919691 [PubMed - indexed for MEDLINE]Related articlesFree article

Acid ceramidase overexpression prevents the inhibitory effects of saturated fatty acids on insulin signaling.

Chavez JA, Holland WL, Bär J, Sandhoff K, Summers SA.

J Biol Chem. 2005 May 20;280(20):20148-53. Epub 2005 Mar 17.PMID: 15774472 [PubMed - indexed for MEDLINE]Related articlesFree article

A role for sphingolipids in producing the common features of type 2 diabetes, metabolic syndrome X, and Cushing's syndrome.

Summers SA, Nelson DH.

Diabetes. 2005 Mar;54(3):591-602. Review.PMID: 15734832 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of a membrane-targeted sphingosine kinase 1 on cell proliferation and survival.

Safadi-Chamberlain F, Wang LP, Payne SG, Lim CU, Stratford S, Chavez JA, Fox MH, Spiegel S, Summers SA.

Biochem J. 2005 Jun 15;388(Pt 3):827-34.PMID: 15693752 [PubMed - indexed for MEDLINE]Related articlesFree article

Fat-cell mass, serum leptin and adiponectin changes during weight gain and loss in yellow-bellied marmots (Marmota flaviventris).

Florant GL, Porst H, Peiffer A, Hudachek SF, Pittman C, Summers SA, Rajala MW, Scherer PE.

J Comp Physiol B. 2004 Nov;174(8):633-9. Epub 2004 Oct 29.PMID: 15517283 [PubMed - indexed for MEDLINE]Related articles

Successful re-introduction of recombinant human erythropoietin following antibody induced pure red cell aplasia.

Summers SA, Matijevic A, Almond MK.

Nephrol Dial Transplant. 2004 Aug;19(8):2137-9. No abstract available. PMID: 15252175 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B.

Stratford S, Hoehn KL, Liu F, Summers SA.

J Biol Chem. 2004 Aug 27;279(35):36608-15. Epub 2004 Jun 25.PMID: 15220355 [PubMed - indexed for MEDLINE]Related articlesFree article

Seasonal, tissue-specific regulation of Akt/protein kinase B and glycogen synthase in hibernators.

Hoehn KL, Hudachek SF, Summers SA, Florant GL.

Am J Physiol Regul Integr Comp Physiol. 2004 Mar;286(3):R498-504. Epub 2003 Dec 4.PMID: 14656767 [PubMed - indexed for MEDLINE]Related articles

Characterizing the effects of saturated fatty acids on insulin signaling and ceramide and diacylglycerol accumulation in 3T3-L1 adipocytes and C2C12 myotubes.

Chavez JA, Summers SA.

Arch Biochem Biophys. 2003 Nov 15;419(2):101-9.PMID: 14592453 [PubMed - indexed for MEDLINE]Related articles

Assaying AKT/protein kinase B activity.

Hoehn KL, Summers SA.

Methods Mol Med. 2003;83:137-44. No abstract available. PMID: 12619725 [PubMed - indexed for MEDLINE]Related articles

Measuring insulin-stimulated phosphatidyl-inositol 3-kinase activity.

Wang LP, Summers SA.

Methods Mol Med. 2003;83:127-36. No abstract available. PMID: 12619724 [PubMed - indexed for MEDLINE]Related articles

A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids.

Chavez JA, Knotts TA, Wang LP, Li G, Dobrowsky RT, Florant GL, Summers SA.

J Biol Chem. 2003 Mar 21;278(12):10297-303. Epub 2003 Jan 13.PMID: 12525490 [PubMed - indexed for MEDLINE]Related articlesFree article

Behavioral, metabolic, and molecular correlates of lower insulin sensitivity in Mexican-Americans.

Ho RC, Davy KP, Hickey MS, Summers SA, Melby CL.

Am J Physiol Endocrinol Metab. 2002 Oct;283(4):E799-808.PMID: 12217898 [PubMed - indexed for MEDLINE]Related articlesFree article

Ceramide dissociates 3'-phosphoinositide production from pleckstrin homology domain translocation.

Stratford S, DeWald DB, Summers SA.

Biochem J. 2001 Mar 1;354(Pt 2):359-68.PMID: 11171115 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin signaling in the adipocyte.

Summers SA, Whiteman EL, Birnbaum MJ.

Int J Obes Relat Metab Disord. 2000 Nov;24 Suppl 4:S67-70. Review.PMID: 11126246 [PubMed - indexed for MEDLINE]Related articles

Signaling pathways mediating insulin-stimulated glucose transport.

Summers SA, Yin VP, Whiteman EL, Garza LA, Cho H, Tuttle RL, Birnbaum MJ.

Ann N Y Acad Sci. 1999 Nov 18;892:169-86. Review.PMID: 10842662 [PubMed - indexed for MEDLINE]Related articles

Identification of wortmannin-sensitive targets in 3T3-L1 adipocytes. DissociationoOf insulin-stimulated glucose uptake and glut4 translocation.

Hausdorff SF, Fingar DC, Morioka K, Garza LA, Whiteman EL, Summers SA, Birnbaum MJ.

J Biol Chem. 1999 Aug 27;274(35):24677-84.PMID: 10455135 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase A-dependent and -independent signaling pathways contribute to cyclic AMP-stimulated proliferation.

Cass LA, Summers SA, Prendergast GV, Backer JM, Birnbaum MJ, Meinkoth JL.

Mol Cell Biol. 1999 Sep;19(9):5882-91.PMID: 10454535 [PubMed - indexed for MEDLINE]Related articlesFree article

Differentiation-dependent suppression of platelet-derived growth factor signaling in cultured adipocytes.

Summers SA, Whiteman EL, Cho H, Lipfert L, Birnbaum MJ.

J Biol Chem. 1999 Aug 20;274(34):23858-67.PMID: 10446150 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism.

Summers SA, Kao AW, Kohn AD, Backus GS, Roth RA, Pessin JE, Birnbaum MJ.

J Biol Chem. 1999 Jun 18;274(25):17934-40.PMID: 10364240 [PubMed - indexed for MEDLINE]Related articlesFree article

Steroidogenic acute regulatory protein (StAR) is a sterol transfer protein.

Kallen CB, Billheimer JT, Summers SA, Stayrook SE, Lewis M, Strauss JF 3rd.

J Biol Chem. 1998 Oct 9;273(41):26285-8.PMID: 9756854 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of insulin-stimulated glucose transporter GLUT4 translocation and Akt kinase activity by ceramide.

Summers SA, Garza LA, Zhou H, Birnbaum MJ.

Mol Cell Biol. 1998 Sep;18(9):5457-64.PMID: 9710629 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of Akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis.

Zhou H, Summers SA, Birnbaum MJ, Pittman RN.

J Biol Chem. 1998 Jun 26;273(26):16568-75.PMID: 9632728 [PubMed - indexed for MEDLINE]Related articlesFree article

Construction and characterization of a conditionally active version of the serine/threonine kinase Akt.

Kohn AD, Barthel A, Kovacina KS, Boge A, Wallach B, Summers SA, Birnbaum MJ, Scott PH, Lawrence JC Jr, Roth RA.

J Biol Chem. 1998 May 8;273(19):11937-43.PMID: 9565622 [PubMed - indexed for MEDLINE]Related articlesFree article

Polyoma middle T antigen activates the Ser/Thr kinase Akt in a PI3-kinase-dependent manner.

Summers SA, Lipfert L, Birnbaum MJ.

Biochem Biophys Res Commun. 1998 May 8;246(1):76-81.PMID: 9600071 [PubMed - indexed for MEDLINE]Related articles

A role for the serine/threonine kinase, Akt, in insulin-stimulated glucose uptake.

Summers SA, Birnbaum MJ.

Biochem Soc Trans. 1997 Aug;25(3):981-8. Review. No abstract available. PMID: 9388586 [PubMed - indexed for MEDLINE]Related articles

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation.

Kohn AD, Summers SA, Birnbaum MJ, Roth RA.

J Biol Chem. 1996 Dec 6;271(49):31372-8.PMID: 8940145 [PubMed - indexed for MEDLINE]Related articlesFree article

Polyphosphoinositide inclusion in artificial lipid bilayer vesicles promotes divalent cation-dependent membrane fusion.

Summers SA, Guebert BA, Shanahan MF.

Biophys J. 1996 Dec;71(6):3199-206.PMID: 8968590 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose transport activity and ligand binding (cytochalasin B, IAPS-forskolin) of chimeric constructs of GLUT2 and GLUT4 expressed in COS-7-cells.

Wandel S, Buchs A, Schürmann A, Summers SA, Powers AC, Shanahan MF, Joost HG.

Biochim Biophys Acta. 1996 Oct 2;1284(1):56-62.PMID: 8865815 [PubMed - indexed for MEDLINE]Related articles

Mutation of two conserved arginine residues in the glucose transporter GLUT4 supresses transport activity, but not glucose-inhibitable binding of inhibitory ligands.

Wandel S, Schurmann A, Becker W, Summers SA, Shanahan MF, Joost HG.

Naunyn Schmiedebergs Arch Pharmacol. 1995 Dec;353(1):36-41.PMID: 8750914 [PubMed - indexed for MEDLINE]Related articles

Substitution of conserved tyrosine residues in helix 4 (Y143) and 7 (Y293) affects the activity, but not IAPS-forskolin binding, of the glucose transporter GLUT4.

Wandel S, Schürmann A, Becker W, Summers SA, Shanahan MF, Joost HG.

FEBS Lett. 1994 Jul 11;348(2):114-8. Erratum in: FEBS Lett 1997 Aug 25;413(3):495. PMID: 8034025 [PubMed - indexed for MEDLINE]Related articles

Alternative bases for choice in probabilistic discrimination.

Summers SA.

J Exp Psychol. 1968 Apr;76(4):538-43. No abstract available. PMID: 5650567 [PubMed - indexed for MEDLINE]Related articles

The learning of responses to multiple weighted cues.

SUMMERS SA.

J Exp Psychol. 1962 Jul;64:29-34. No abstract available. PMID: 13918385 [PubMed - indexed for MEDLINE]Related articles