PubMed

Role of aquaporin 9 in cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes.

Shinkai Y, Sumi D, Toyama T, Kaji T, Kumagai Y.

Toxicol Appl Pharmacol. 2009 Jun 1;237(2):232-6. Epub 2009 Mar 31.PMID: 19341753 [PubMed - indexed for MEDLINE]Related articles

Reduction of arginase I activity and manganese levels in the liver during exposure of rats to methylmercury: a possible mechanism.

Kanda H, Sumi D, Endo A, Toyama T, Chen CL, Kikushima M, Kumagai Y.

Arch Toxicol. 2008 Nov;82(11):803-8. Epub 2008 May 17.PMID: 18488197 [PubMed - indexed for MEDLINE]Related articles

Redox cycling of 9,10-phenanthraquinone to cause oxidative stress is terminated through its monoglucuronide conjugation in human pulmonary epithelial A549 cells.

Taguchi K, Shimada M, Fujii S, Sumi D, Pan X, Yamano S, Nishiyama T, Hiratsuka A, Yamamoto M, Cho AK, Froines JR, Kumagai Y.

Free Radic Biol Med. 2008 Apr 15;44(8):1645-55. Epub 2008 Feb 9.PMID: 18294972 [PubMed - indexed for MEDLINE]Related articles

L-Xylulose reductase is involved in 9,10-phenanthrenequinone-induced apoptosis in human T lymphoma cells.

Matsunaga T, Kamiya T, Sumi D, Kumagai Y, Kalyanaraman B, Hara A.

Free Radic Biol Med. 2008 Mar 15;44(6):1191-202. Epub 2008 Jan 17.PMID: 18206670 [PubMed - indexed for MEDLINE]Related articles

[Chemical biology of 1,2-naphthoquinone, a novel air pollutant that affects signal transduction pathways]

Sumi D, Kumagai Y.

Yakugaku Zasshi. 2007 Dec;127(12):1949-56. Review. Japanese. PMID: 18057784 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytoprotective role of Nrf2/Keap1 system in methylmercury toxicity.

Toyama T, Sumi D, Shinkai Y, Yasutake A, Taguchi K, Tong KI, Yamamoto M, Kumagai Y.

Biochem Biophys Res Commun. 2007 Nov 23;363(3):645-50. Epub 2007 Sep 18.PMID: 17904103 [PubMed - indexed for MEDLINE]Related articles

Chemical knockdown of protein-tyrosine phosphatase 1B by 1,2-naphthoquinone through covalent modification causes persistent transactivation of epidermal growth factor receptor.

Iwamoto N, Sumi D, Ishii T, Uchida K, Cho AK, Froines JR, Kumagai Y.

J Biol Chem. 2007 Nov 16;282(46):33396-404. Epub 2007 Sep 18.PMID: 17878162 [PubMed - indexed for MEDLINE]Related articlesFree article

Downregulation of arginase II and renal apoptosis by inorganic mercury: overexpression of arginase II reduces its apoptosis.

Kanda H, Kikushima M, Homma-Takeda S, Sumi D, Endo A, Toyama T, Miura N, Naganuma A, Kumagai Y.

Arch Toxicol. 2008 Feb;82(2):67-73. Epub 2007 Sep 14.PMID: 17874066 [PubMed - indexed for MEDLINE]Related articles

1,2-Naphthoquinone disrupts the function of cAMP response element-binding protein through covalent modification.

Endo A, Sumi D, Kumagai Y.

Biochem Biophys Res Commun. 2007 Sep 14;361(1):243-8. Epub 2007 Jul 16.PMID: 17658470 [PubMed - indexed for MEDLINE]Related articles

Activation of the Nrf2 pathway, but decreased gamma-glutamylcysteine synthetase heavy subunit chain levels and caspase-3-dependent apoptosis during exposure of primary mouse hepatocytes to diphenylarsinic acid.

Sumi D, Manji A, Shinkai Y, Toyama T, Kumagai Y.

Toxicol Appl Pharmacol. 2007 Sep 15;223(3):218-24. Epub 2007 Jun 18.PMID: 17628625 [PubMed - indexed for MEDLINE]Related articles

Effects of naphthoquinone on airway responsiveness in the presence or absence of antigen in mice.

Inoue K, Takano H, Ichinose T, Tomura S, Yanagisawa R, Sakurai M, Sumi D, Cho AK, Hiyoshi K, Kumagai Y.

Arch Toxicol. 2007 Aug;81(8):575-81. Epub 2007 Feb 22.PMID: 17318628 [PubMed - indexed for MEDLINE]Related articles

Effects of a pomegranate fruit extract rich in punicalagin on oxidation-sensitive genes and eNOS activity at sites of perturbed shear stress and atherogenesis.

de Nigris F, Williams-Ignarro S, Sica V, Lerman LO, D'Armiento FP, Byrns RE, Casamassimi A, Carpentiero D, Schiano C, Sumi D, Fiorito C, Ignarro LJ, Napoli C.

Cardiovasc Res. 2007 Jan 15;73(2):414-23. Epub 2006 Sep 1.PMID: 17014835 [PubMed - indexed for MEDLINE]Related articlesFree article

Arsenic: signal transduction, transcription factor, and biotransformation involved in cellular response and toxicity.

Kumagai Y, Sumi D.

Annu Rev Pharmacol Toxicol. 2007;47:243-62. Review.PMID: 17002598 [PubMed - indexed for MEDLINE]Related articles

Modulating role of estradiol on arginase II expression in hyperlipidemic rabbits as an atheroprotective mechanism.

Hayashi T, Esaki T, Sumi D, Mukherjee T, Iguchi A, Chaudhuri G.

Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10485-90. Epub 2006 Jun 26.PMID: 16801563 [PubMed - indexed for MEDLINE]Related articlesFree article

Pomegranate juice protects nitric oxide against oxidative destruction and enhances the biological actions of nitric oxide.

Ignarro LJ, Byrns RE, Sumi D, de Nigris F, Napoli C.

Nitric Oxide. 2006 Sep;15(2):93-102. Epub 2006 Apr 19.PMID: 16626982 [PubMed - indexed for MEDLINE]Related articles

Serine 1179 phosphorylation of endothelial nitric oxide synthase caused by 2,4,6-trinitrotoluene through PI3K/Akt signaling in endothelial cells.

Sun Y, Sumi D, Kumagai Y.

Toxicol Appl Pharmacol. 2006 Jul 1;214(1):55-60. Epub 2006 Mar 3.PMID: 16516256 [PubMed - indexed for MEDLINE]Related articles

Sulforaphane, an activator of Nrf2, suppresses cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes.

Shinkai Y, Sumi D, Fukami I, Ishii T, Kumagai Y.

FEBS Lett. 2006 Mar 20;580(7):1771-4. Epub 2006 Feb 24.PMID: 16516206 [PubMed - indexed for MEDLINE]Related articles

Selective iNOS inhibitor, ONO1714 successfully retards the development of high-cholesterol diet induced atherosclerosis by novel mechanism.

Hayashi T, Matsui-Hirai H, Fukatsu A, Sumi D, Kano-Hayashi H, Rani P JA, Iguchi A.

Atherosclerosis. 2006 Aug;187(2):316-24. Epub 2005 Dec 1.PMID: 16325187 [PubMed - indexed for MEDLINE]Related articles

Beneficial effects of concurrent autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the mouse hindlimb.

Napoli C, Williams-Ignarro S, de Nigris F, de Rosa G, Lerman LO, Farzati B, Matarazzo A, Sica G, Botti C, Fiore A, Byrns RE, Sumi D, Sica V, Ignarro LJ.

Proc Natl Acad Sci U S A. 2005 Nov 22;102(47):17202-6. Epub 2005 Nov 14.PMID: 16286655 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of endothelial nitric oxide synthase activity and suppression of endothelium-dependent vasorelaxation by 1,2-naphthoquinone, a component of diesel exhaust particles.

Sun Y, Taguchi K, Sumi D, Yamano S, Kumagai Y.

Arch Toxicol. 2006 May;80(5):280-5. Epub 2005 Oct 25.PMID: 16247599 [PubMed - indexed for MEDLINE]Related articles

2,4,6-Trinitrotoluene inhibits endothelial nitric oxide synthase activity and elevates blood pressure in rats.

Sun Y, Iemitsu M, Shimojo N, Miyauchi T, Amamiya M, Sumi D, Hayashi T, Sun G, Shimojo N, Kumagai Y.

Arch Toxicol. 2005 Dec;79(12):705-10. Epub 2005 Jul 16.PMID: 16025313 [PubMed - indexed for MEDLINE]Related articles

NADPH oxidase inhibitor, apocynin, restores the impaired endothelial-dependent and -independent responses and scavenges superoxide anion in rats with type 2 diabetes complicated by NO dysfunction.

Hayashi T, Juliet PA, Kano-Hayashi H, Tsunekawa T, Dingqunfang D, Sumi D, Matsui-Hirai H, Fukatsu A, Iguchi A.

Diabetes Obes Metab. 2005 Jul;7(4):334-43.PMID: 15955119 [PubMed - indexed for MEDLINE]Related articles

Sp1 transcription factor expression is regulated by estrogen-related receptor alpha1.

Sumi D, Ignarro LJ.

Biochem Biophys Res Commun. 2005 Mar 4;328(1):165-72.PMID: 15670765 [PubMed - indexed for MEDLINE]Related articles

A new HMG-CoA reductase inhibitor, pitavastatin remarkably retards the progression of high cholesterol induced atherosclerosis in rabbits.

Hayashi T, Rani P JA, Fukatsu A, Matsui-Hirai H, Osawa M, Miyazaki A, Tsunekawa T, Kano-Hayashi H, Iguchi A, Sumi D, Ignarro LJ.

Atherosclerosis. 2004 Oct;176(2):255-63.PMID: 15380447 [PubMed - indexed for MEDLINE]Related articles

Regulation of inducible nitric oxide synthase expression in advanced glycation end product-stimulated raw 264.7 cells: the role of heme oxygenase-1 and endogenous nitric oxide.

Sumi D, Ignarro LJ.

Diabetes. 2004 Jul;53(7):1841-50.PMID: 15220209 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide: inhibitory effects on endothelial cell calcium signaling, prostaglandin I2 production and nitric oxide synthase expression.

Takeuchi K, Watanabe H, Tran QK, Ozeki M, Sumi D, Hayashi T, Iguchi A, Ignarro LJ, Ohashi K, Hayashi H.

Cardiovasc Res. 2004 Apr 1;62(1):194-201.PMID: 15023566 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene transfer of endothelial NO synthase, but not eNOS plus inducible NOS, regressed atherosclerosis in rabbits.

Hayashi T, Sumi D, Juliet PA, Matsui-Hirai H, Asai-Tanaka Y, Kano H, Fukatsu A, Tsunekawa T, Miyazaki A, Iguchi A, Ignarro LJ.

Cardiovasc Res. 2004 Feb 1;61(2):339-51.PMID: 14736551 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased expression of elastolytic cysteine proteases, cathepsins S and K, in the neointima of balloon-injured rat carotid arteries.

Cheng XW, Kuzuya M, Sasaki T, Arakawa K, Kanda S, Sumi D, Koike T, Maeda K, Tamaya-Mori N, Shi GP, Saito N, Iguchi A.

Am J Pathol. 2004 Jan;164(1):243-51.PMID: 14695337 [PubMed - indexed for MEDLINE]Related articlesFree article

Estrogen-related receptor alpha 1 up-regulates endothelial nitric oxide synthase expression.

Sumi D, Ignarro LJ.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14451-6. Epub 2003 Nov 10.PMID: 14610283 [PubMed - indexed for MEDLINE]Related articlesFree article

Sarpogrelate HCl, a selective 5-HT2A antagonist, retards the progression of atherosclerosis through a novel mechanism.

Hayashi T, Sumi D, Matsui-Hirai H, Fukatsu A, Arockia Rani P J, Kano H, Tsunekawa T, Iguchi A.

Atherosclerosis. 2003 May;168(1):23-31.PMID: 12732383 [PubMed - indexed for MEDLINE]Related articles

17beta-estradiol inhibits NADPH oxidase activity through the regulation of p47phox mRNA and protein expression in THP-1 cells.

Sumi D, Hayashi T, Matsui-Hirai H, Jacobs AT, Ignarro LJ, Iguchi A.

Biochim Biophys Acta. 2003 May 12;1640(2-3):113-8.PMID: 12729920 [PubMed - indexed for MEDLINE]Related articles

Estriol retards and stabilizes atherosclerosis through an NO-mediated system.

Kano H, Hayashi T, Sumi D, Matusi-Hirai H, Tsunekawa T, Endo H, Iguchi A.

Life Sci. 2002 May 24;71(1):31-42.PMID: 12020746 [PubMed - indexed for MEDLINE]Related articles

The long-term effect of estriol on endothelial function and bone mineral density in octogenarian women.

Hayashi T, Kano H, Sumi D, Iguchi A, Ito I, Endo H.

J Am Geriatr Soc. 2002 Apr;50(4):777-8. No abstract available. PMID: 11982688 [PubMed - indexed for MEDLINE]Related articles

Anti-atherosclerotic effect of beta-blocker with nitric oxide-releasing action on the severe atherosclerosis.

Thakur NK, Hayashi T, Sumi D, Kano H, Matsui-Hirai H, Tsunekawa T, Iguchi A.

J Cardiovasc Pharmacol. 2002 Feb;39(2):298-309.PMID: 11791016 [PubMed - indexed for MEDLINE]Related articles

Estrogen prevents destabilization of endothelial nitric oxide synthase mRNA induced by tumor necrosis factor alpha through estrogen receptor mediated system.

Sumi D, Hayashi T, Jayachandran M, Iguchi A.

Life Sci. 2001 Aug 24;69(14):1651-60.PMID: 11589505 [PubMed - indexed for MEDLINE]Related articles

Temporal effects of 17beta-estradiol on caveolin-1 mRNA and protein in bovine aortic endothelial cells.

Jayachandran M, Hayashi T, Sumi D, Iguchi A, Miller VM.

Am J Physiol Heart Circ Physiol. 2001 Sep;281(3):H1327-33. Erratum in: Am J Physiol Heart Circ Physiol 2001 Dec;281(6):section H following table of contents. Am J Physiol Heart Circ Physiol 2001 Nov;281(5):section H following table of contents. PMID: 11514304 [PubMed - indexed for MEDLINE]Related articlesFree article

Cerivastatin, a hydroxymethylglutaryl coenzyme a reductase inhibitor, improves endothelial function in elderly diabetic patients within 3 days.

Tsunekawa T, Hayashi T, Kano H, Sumi D, Matsui-Hirai H, Thakur NK, Egashira K, Iguchi A.

Circulation. 2001 Jul 24;104(4):376-9.PMID: 11468195 [PubMed - indexed for MEDLINE]Related articlesFree article

HMG-CoA reductase inhibitor stabilizes rabbit atheroma by increasing basal NO and decreasing superoxide.

Thakur NK, Hayashi T, Sumi D, Kano H, Tsunekawa T, Iguchi A.

Am J Physiol Heart Circ Physiol. 2001 Jul;281(1):H75-83.PMID: 11406471 [PubMed - indexed for MEDLINE]Related articlesFree article

A HMG-CoA reductase inhibitor possesses a potent anti-atherosclerotic effect other than serum lipid lowering effects--the relevance of endothelial nitric oxide synthase and superoxide anion scavenging action.

Sumi D, Hayashi T, Thakur NK, Jayachandran M, Asai Y, Kano H, Matsui H, Iguchi A.

Atherosclerosis. 2001 Apr;155(2):347-57.PMID: 11254905 [PubMed - indexed for MEDLINE]Related articles

Up-regulation of endothelial nitric oxide synthase through beta(2)-adrenergic receptor--the role of a beta-blocker with NO-releasing action.

Jayachandran M, Hayashi T, Sumi D, Thakur NK, Kano H, Ignarro LJ, Iguchi A.

Biochem Biophys Res Commun. 2001 Jan 26;280(3):589-94.PMID: 11162560 [PubMed - indexed for MEDLINE]Related articles

Expression of inducible nitric oxide synthase and Fas/Fas ligand correlates with the incidence of apoptotic cell death in atheromatous plaques of human coronary arteries.

Esaki T, Hayashi T, Muto E, Kano H, Kumar TN, Asai Y, Sumi D, Iguchi A.

Nitric Oxide. 2000 Dec;4(6):561-71.PMID: 11139364 [PubMed - indexed for MEDLINE]Related articles

Inhibition of inducible nitric oxide synthase gene expression by indomethacin or ibuprofen in beta-amyloid protein-stimulated J774 cells.

Ogawa O, Umegaki H, Sumi D, Hayashi T, Nakamura A, Thakur NK, Yoshimura J, Endo H, Iguchi A.

Eur J Pharmacol. 2000 Nov 17;408(2):137-41.PMID: 11080519 [PubMed - indexed for MEDLINE]Related articles

Physiological concentration of 17beta-estradiol retards the progression of severe atherosclerosis induced by a high-cholesterol diet plus balloon catheter injury: role of NO.

Hayashi T, Jayachandran M, Sumi D, Thakur NK, Esaki T, Muto E, Kano H, Asai Y, Iguchi A.

Arterioscler Thromb Vasc Biol. 2000 Jun;20(6):1613-21.PMID: 10845880 [PubMed - indexed for MEDLINE]Related articlesFree article

Dehydroepiandrosterone retards atherosclerosis formation through its conversion to estrogen: the possible role of nitric oxide.

Hayashi T, Esaki T, Muto E, Kano H, Asai Y, Thakur NK, Sumi D, Jayachandran M, Iguchi A.

Arterioscler Thromb Vasc Biol. 2000 Mar;20(3):782-92.PMID: 10712404 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelium-dependent relaxation of rabbit atherosclerotic aorta was not restored by control of hyperlipidemia: the possible role of peroxynitrite (ONOO(-)).

Hayashi T, Yamada K, Esaki T, Kano H, Asai Y, Kumar Thakur N, Jayachandran M, Sumi D, Iguchi A.

Atherosclerosis. 1999 Dec;147(2):349-63.PMID: 10559521 [PubMed - indexed for MEDLINE]Related articles

A HMG-CoA reductase inhibitor improved regression of atherosclerosis in the rabbit aorta without affecting serum lipid levels: possible relevance of up-regulation of endothelial NO synthase mRNA.

Kano H, Hayashi T, Sumi D, Esaki T, Asai Y, Thakur NK, Jayachandran M, Iguchi A.

Biochem Biophys Res Commun. 1999 Jun 7;259(2):414-9.PMID: 10362523 [PubMed - indexed for MEDLINE]Related articles

Import into mitochondria of phospholipid hydroperoxide glutathione peroxidase requires a leader sequence.

Arai M, Imai H, Sumi D, Imanaka T, Takano T, Chiba N, Nakagawa Y.

Biochem Biophys Res Commun. 1996 Oct 14;227(2):433-9.PMID: 8878533 [PubMed - indexed for MEDLINE]Related articles

Overexpression of phospholipid hydroperoxide glutathione peroxidase suppressed cell death due to oxidative damage in rat basophile leukemia cells (RBL-2H3).

Imai H, Sumi D, Sakamoto H, Hanamoto A, Arai M, Chiba N, Nakagawa Y.

Biochem Biophys Res Commun. 1996 May 15;222(2):432-8.PMID: 8670223 [PubMed - indexed for MEDLINE]Related articles

Molecular cloning and functional expression of a cDNA for rat phospholipid hydroperoxide glutathione peroxidase: 3'-untranslated region of the gene is necessary for functional expression.

Imai H, Sumi D, Hanamoto A, Arai M, Sugiyama A.

J Biochem. 1995 Nov;118(5):1061-7.PMID: 8749327 [PubMed - indexed for MEDLINE]Related articles