PubMed

The skinny on fat: lipolysis and fatty acid utilization in adipocytes.

Ahmadian M, Duncan RE, Sul HS.

Trends Endocrinol Metab. 2009 Nov;20(9):424-8. Epub 2009 Sep 30.PMID: 19796963 [PubMed - in process]Related articles

Characterization of desnutrin functional domains:Critical residues for triacylglycerol hydrolysis in cultured cells.

Duncan RE, Wang Y, Ahmadian M, Lu J, Sarkadi-Nagy E, Sul HS.

J Lipid Res. 2009 Aug 19. [Epub ahead of print]PMID: 19692632 [PubMed - as supplied by publisher]Related articlesFree article

DNA-PK: relaying the insulin signal to USF in lipogenesis.

Wong RH, Sul HS.

Cell Cycle. 2009 Jul 1;8(13):1977-8. Epub 2009 Jul 15. No abstract available. PMID: 19550139 [PubMed - indexed for MEDLINE]Related articles

Minireview: Pref-1: role in adipogenesis and mesenchymal cell fate.

Sul HS.

Mol Endocrinol. 2009 Nov;23(11):1717-25. Epub 2009 Jun 18.PMID: 19541743 [PubMed - in process]Related articles

Identification of Dlk1, Ptpru and Klhl1 as novel Nurr1 target genes in meso-diencephalic dopamine neurons.

Jacobs FM, van der Linden AJ, Wang Y, von Oerthel L, Sul HS, Burbach JP, Smidt MP.

Development. 2009 Jul;136(14):2363-73. Epub 2009 Jun 10.PMID: 19515692 [PubMed - indexed for MEDLINE]Related articles

A role of DNA-PK for the metabolic gene regulation in response to insulin.

Wong RH, Chang I, Hudak CS, Hyun S, Kwan HY, Sul HS.

Cell. 2009 Mar 20;136(6):1056-72.PMID: 19303849 [PubMed - indexed for MEDLINE]Related articles

Pref-1 regulates mesenchymal cell commitment and differentiation through Sox9.

Wang Y, Sul HS.

Cell Metab. 2009 Mar;9(3):287-302.PMID: 19254573 [PubMed - indexed for MEDLINE]Related articles

AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency.

Jaworski K, Ahmadian M, Duncan RE, Sarkadi-Nagy E, Varady KA, Hellerstein MK, Lee HY, Samuel VT, Shulman GI, Kim KH, de Val S, Kang C, Sul HS.

Nat Med. 2009 Feb;15(2):159-68. Epub 2009 Jan 11.PMID: 19136964 [PubMed - indexed for MEDLINE]Related articles

Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity.

Ahmadian M, Duncan RE, Varady KA, Frasson D, Hellerstein MK, Birkenfeld AL, Samuel VT, Shulman GI, Wang Y, Kang C, Sul HS.

Diabetes. 2009 Apr;58(4):855-66. Epub 2009 Jan 9.PMID: 19136649 [PubMed - indexed for MEDLINE]Related articlesFree article

Resistance to high-fat diet-induced obesity but exacerbated insulin resistance in mice overexpressing preadipocyte factor-1 (Pref-1): a new model of partial lipodystrophy.

Villena JA, Choi CS, Wang Y, Kim S, Hwang YJ, Kim YB, Cline G, Shulman GI, Sul HS.

Diabetes. 2008 Dec;57(12):3258-66. Epub 2008 Oct 3.PMID: 18835937 [PubMed - indexed for MEDLINE]Related articlesFree article

Identification and functional characterization of adipose-specific phospholipase A2 (AdPLA).

Duncan RE, Sarkadi-Nagy E, Jaworski K, Ahmadian M, Sul HS.

J Biol Chem. 2008 Sep 12;283(37):25428-36. Epub 2008 Jul 9.PMID: 18614531 [PubMed - indexed for MEDLINE]Related articlesFree article

Triacylglycerol metabolism in adipose tissue.

Ahmadian M, Duncan RE, Jaworski K, Sarkadi-Nagy E, Sul HS.

Future Lipidol. 2007 Apr;2(2):229-237.PMID: 19194515 [PubMed]Related articlesFree article

Regulation of lipolysis in adipocytes.

Duncan RE, Ahmadian M, Jaworski K, Sarkadi-Nagy E, Sul HS.

Annu Rev Nutr. 2007;27:79-101. Review.PMID: 17313320 [PubMed - indexed for MEDLINE]Related articles

Regulation of triglyceride metabolism. IV. Hormonal regulation of lipolysis in adipose tissue.

Jaworski K, Sarkadi-Nagy E, Duncan RE, Ahmadian M, Sul HS.

Am J Physiol Gastrointest Liver Physiol. 2007 Jul;293(1):G1-4. Epub 2007 Jan 11. Review.PMID: 17218471 [PubMed - indexed for MEDLINE]Related articlesFree article

Pref-1 (preadipocyte factor 1) activates the MEK/extracellular signal-regulated kinase pathway to inhibit adipocyte differentiation.

Kim KA, Kim JH, Wang Y, Sul HS.

Mol Cell Biol. 2007 Mar;27(6):2294-308. Epub 2007 Jan 8.PMID: 17210639 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct interaction between USF and SREBP-1c mediates synergistic activation of the fatty-acid synthase promoter.

Griffin MJ, Wong RH, Pandya N, Sul HS.

J Biol Chem. 2007 Feb 23;282(8):5453-67. Epub 2006 Dec 31.PMID: 17197698 [PubMed - indexed for MEDLINE]Related articlesFree article

Dissociation between adipose tissue fluxes and lipogenic gene expression in ob/ob mice.

Turner SM, Roy S, Sul HS, Neese RA, Murphy EJ, Samandi W, Roohk DJ, Hellerstein MK.

Am J Physiol Endocrinol Metab. 2007 Apr;292(4):E1101-9. Epub 2006 Dec 12.PMID: 17164440 [PubMed - indexed for MEDLINE]Related articlesFree article

Pref-1, a preadipocyte secreted factor that inhibits adipogenesis.

Wang Y, Kim KA, Kim JH, Sul HS.

J Nutr. 2006 Dec;136(12):2953-6.PMID: 17116701 [PubMed - indexed for MEDLINE]Related articlesFree article

Ectodomain shedding of preadipocyte factor 1 (Pref-1) by tumor necrosis factor alpha converting enzyme (TACE) and inhibition of adipocyte differentiation.

Wang Y, Sul HS.

Mol Cell Biol. 2006 Jul;26(14):5421-35.PMID: 16809777 [PubMed - indexed for MEDLINE]Related articlesFree article

Dlk1 in normal and abnormal hematopoiesis.

Sakajiri S, O'kelly J, Yin D, Miller CW, Hofmann WK, Oshimi K, Shih LY, Kim KH, Sul HS, Jensen CH, Teisner B, Kawamata N, Koeffler HP.

Leukemia. 2005 Aug;19(8):1404-10.PMID: 15959531 [PubMed - indexed for MEDLINE]Related articles

Insulin regulation of fatty acid synthase gene transcription: roles of USF and SREBP-1c.

Griffin MJ, Sul HS.

IUBMB Life. 2004 Oct;56(10):595-600. Review.PMID: 15814457 [PubMed - indexed for MEDLINE]Related articles

Resistin/ADSF/FIZZ3 in obesity and diabetes.

Sul HS.

Trends Endocrinol Metab. 2004 Aug;15(6):247-9.PMID: 15358276 [PubMed - indexed for MEDLINE]Related articles

Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis.

Villena JA, Roy S, Sarkadi-Nagy E, Kim KH, Sul HS.

J Biol Chem. 2004 Nov 5;279(45):47066-75. Epub 2004 Aug 27.PMID: 15337759 [PubMed - indexed for MEDLINE]Related articlesFree article

Induced adiposity and adipocyte hypertrophy in mice lacking the AMP-activated protein kinase-alpha2 subunit.

Villena JA, Viollet B, Andreelli F, Kahn A, Vaulont S, Sul HS.

Diabetes. 2004 Sep;53(9):2242-9.PMID: 15331533 [PubMed - indexed for MEDLINE]Related articlesFree article

Dominant inhibitory adipocyte-specific secretory factor (ADSF)/resistin enhances adipogenesis and improves insulin sensitivity.

Kim KH, Zhao L, Moon Y, Kang C, Sul HS.

Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6780-5. Epub 2004 Apr 16.PMID: 15090646 [PubMed - indexed for MEDLINE]Related articlesFree article

Occupancy and function of the -150 sterol regulatory element and -65 E-box in nutritional regulation of the fatty acid synthase gene in living animals.

Latasa MJ, Griffin MJ, Moon YS, Kang C, Sul HS.

Mol Cell Biol. 2003 Aug;23(16):5896-907.PMID: 12897158 [PubMed - indexed for MEDLINE]Related articlesFree article

Pref-1 and ADSF/resistin: two secreted factors inhibiting adipose tissue development.

Villena JA, Kim KH, Sul HS.

Horm Metab Res. 2002 Nov-Dec;34(11-12):664-70. Review.PMID: 12660879 [PubMed - indexed for MEDLINE]Related articles

Inhibition of adipogenesis and development of glucose intolerance by soluble preadipocyte factor-1 (Pref-1).

Lee K, Villena JA, Moon YS, Kim KH, Lee S, Kang C, Sul HS.

J Clin Invest. 2003 Feb;111(4):453-61.PMID: 12588883 [PubMed - indexed for MEDLINE]Related articlesFree article

Mice lacking paternally expressed Pref-1/Dlk1 display growth retardation and accelerated adiposity.

Moon YS, Smas CM, Lee K, Villena JA, Kim KH, Yun EJ, Sul HS.

Mol Cell Biol. 2002 Aug;22(15):5585-92.PMID: 12101250 [PubMed - indexed for MEDLINE]Related articlesFree article

Silencing of the mouse H-rev107 gene encoding a class II tumor suppressor by CpG methylation.

Roder K, Latasa MJ, Sul HS.

J Biol Chem. 2002 Aug 23;277(34):30543-50. Epub 2002 Jun 7.PMID: 12055182 [PubMed - indexed for MEDLINE]Related articlesFree article

Induction of murine H-rev107 gene expression by growth arrest and histone acetylation: involvement of an Sp1/Sp3-binding GC-box.

Roder K, Kim KH, Sul HS.

Biochem Biophys Res Commun. 2002 May 31;294(1):63-70.PMID: 12054741 [PubMed - indexed for MEDLINE]Related articles

Murine H-rev107 gene encoding a class II tumor suppressor: gene organization and identification of an Sp1/Sp3-binding GC-box required for its transcription.

Roder K, Latasa MJ, Sul HS.

Biochem Biophys Res Commun. 2002 May 3;293(2):793-9.PMID: 12054540 [PubMed - indexed for MEDLINE]Related articles

Only the large soluble form of preadipocyte factor-1 (Pref-1), but not the small soluble and membrane forms, inhibits adipocyte differentiation: role of alternative splicing.

Mei B, Zhao L, Chen L, Sul HS.

Biochem J. 2002 May 15;364(Pt 1):137-44.PMID: 11988086 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of fatty acid synthase promoter by polyunsaturated fatty acids.

Moon YS, Latasa MJ, Griffin MJ, Sul HS.

J Lipid Res. 2002 May;43(5):691-8.PMID: 11971939 [PubMed - indexed for MEDLINE]Related articlesFree article

A cysteine-rich adipose tissue-specific secretory factor inhibits adipocyte differentiation.

Kim KH, Lee K, Moon YS, Sul HS.

J Biol Chem. 2001 Apr 6;276(14):11252-6. Epub 2001 Feb 15.PMID: 11278254 [PubMed - indexed for MEDLINE]Related articlesFree article

Function of pref-1 as an inhibitor of adipocyte differentiation.

Sul HS, Smas C, Mei B, Zhou L.

Int J Obes Relat Metab Disord. 2000 Nov;24 Suppl 4:S15-9. Review.PMID: 11126233 [PubMed - indexed for MEDLINE]Related articles

Nutritional regulation of the fatty acid synthase promoter in vivo: sterol regulatory element binding protein functions through an upstream region containing a sterol regulatory element.

Latasa MJ, Moon YS, Kim KH, Sul HS.

Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10619-24.PMID: 10962028 [PubMed - indexed for MEDLINE]Related articlesFree article

Transient induction of ENC-1, a Kelch-related actin-binding protein, is required for adipocyte differentiation.

Zhao L, Gregoire F, Sul HS.

J Biol Chem. 2000 Jun 2;275(22):16845-50.PMID: 10828068 [PubMed - indexed for MEDLINE]Related articlesFree article

Acyltransferases of de novo glycerophospholipid biosynthesis.

Dircks L, Sul HS.

Prog Lipid Res. 1999 Sep-Nov;38(5-6):461-79. Review. No abstract available. PMID: 10793891 [PubMed - indexed for MEDLINE]Related articles

Two 5'-regions are required for nutritional and insulin regulation of the fatty-acid synthase promoter in transgenic mice.

Moon YS, Latasa MJ, Kim KH, Wang D, Sul HS.

J Biol Chem. 2000 Apr 7;275(14):10121-7.PMID: 10744693 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of the fatty acid synthase promoter by insulin.

Sul HS, Latasa MJ, Moon Y, Kim KH.

J Nutr. 2000 Feb;130(2S Suppl):315S-320S. Review.PMID: 10721895 [PubMed - indexed for MEDLINE]Related articlesFree article

A conserved seven amino acid stretch important for murine mitochondrial glycerol-3-phosphate acyltransferase activity. Significance of arginine 318 in catalysis.

Dircks LK, Ke J, Sul HS.

J Biol Chem. 1999 Dec 3;274(49):34728-34.PMID: 10574940 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcriptional repression of pref-1 by glucocorticoids promotes 3T3-L1 adipocyte differentiation.

Smas CM, Chen L, Zhao L, Latasa MJ, Sul HS.

J Biol Chem. 1999 Apr 30;274(18):12632-41.PMID: 10212243 [PubMed - indexed for MEDLINE]Related articlesFree article

Transcriptional control of the pref-1 gene in 3T3-L1 adipocyte differentiation. Sequence requirement for differentiation-dependent suppression.

Smas CM, Kachinskas D, Liu CM, Xie X, Dircks LK, Sul HS.

J Biol Chem. 1998 Nov 27;273(48):31751-8.PMID: 9822638 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin stimulation of the fatty acid synthase promoter is mediated by the phosphatidylinositol 3-kinase pathway. Involvement of protein kinase B/Akt.

Wang D, Sul HS.

J Biol Chem. 1998 Sep 25;273(39):25420-6.PMID: 9738010 [PubMed - indexed for MEDLINE]Related articlesFree article

Nutritional and hormonal regulation of enzymes in fat synthesis: studies of fatty acid synthase and mitochondrial glycerol-3-phosphate acyltransferase gene transcription.

Sul HS, Wang D.

Annu Rev Nutr. 1998;18:331-51. Review.PMID: 9706228 [PubMed - indexed for MEDLINE]Related articles

Understanding adipocyte differentiation.

Gregoire FM, Smas CM, Sul HS.

Physiol Rev. 1998 Jul;78(3):783-809. Review.PMID: 9674695 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of fat synthesis and adipose differentiation.

Sul HS, Smas CM, Wang D, Chen L.

Prog Nucleic Acid Res Mol Biol. 1998;60:317-45. Review.PMID: 9594578 [PubMed - indexed for MEDLINE]Related articles

Mammalian mitochondrial glycerol-3-phosphate acyltransferase.

Dircks LK, Sul HS.

Biochim Biophys Acta. 1997 Sep 4;1348(1-2):17-26. Review.PMID: 9370312 [PubMed - indexed for MEDLINE]Related articles

Upstream stimulatory factor binding to the E-box at -65 is required for insulin regulation of the fatty acid synthase promoter.

Wang D, Sul HS.

J Biol Chem. 1997 Oct 17;272(42):26367-74.PMID: 9334210 [PubMed - indexed for MEDLINE]Related articlesFree article