PubMed

Stem cells are dispensable for lung homeostasis but restore airways after injury.

Giangreco A, Arwert EN, Rosewell IR, Snyder J, Watt FM, Stripp BR.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9286-91. Epub 2009 May 28.PMID: 19478060 [PubMed - indexed for MEDLINE]Related articlesFree article

Clara Cells Attenuate the Inflammatory Response through Regulation of Macrophage Behavior.

Snyder JC, Reynolds SD, Hollingsworth JW, Li Z, Kaminski N, Stripp BR.

Am J Respir Cell Mol Biol. 2009 May 7. [Epub ahead of print]PMID: 19423773 [PubMed - as supplied by publisher]Related articles

beta-Catenin is not necessary for maintenance or repair of the bronchiolar epithelium.

Zemke AC, Teisanu RM, Giangreco A, Drake JA, Brockway BL, Reynolds SD, Stripp BR.

Am J Respir Cell Mol Biol. 2009 Nov;41(5):535-43. Epub 2009 Feb 12.PMID: 19213872 [PubMed - in process]Related articles

Prospective isolation of bronchiolar stem cells based upon immunophenotypic and autofluorescence characteristics.

Teisanu RM, Lagasse E, Whitesides JF, Stripp BR.

Stem Cells. 2009 Mar;27(3):612-22.PMID: 19056905 [PubMed - indexed for MEDLINE]Related articles

Endogenous lung stem cells and contribution to disease.

Snyder JC, Teisanu RM, Stripp BR.

J Pathol. 2009 Jan;217(2):254-64. Review.PMID: 19039828 [PubMed - indexed for MEDLINE]Related articles

Reparative capacity of airway epithelium impacts deposition and remodeling of extracellular matrix.

Snyder JC, Zemke AC, Stripp BR.

Am J Respir Cell Mol Biol. 2009 Jun;40(6):633-42. Epub 2008 Oct 31.PMID: 18978301 [PubMed - indexed for MEDLINE]Related articles

Molecular staging of epithelial maturation using secretory cell-specific genes as markers.

Zemke AC, Snyder JC, Brockway BL, Drake JA, Reynolds SD, Kaminski N, Stripp BR.

Am J Respir Cell Mol Biol. 2009 Mar;40(3):340-8. Epub 2008 Aug 28.PMID: 18757308 [PubMed - indexed for MEDLINE]Related articles

Hierarchical organization of lung progenitor cells: is there an adult lung tissue stem cell?

Stripp BR.

Proc Am Thorac Soc. 2008 Aug 15;5(6):695-8. Review.PMID: 18684719 [PubMed - indexed for MEDLINE]Related articlesFree article

Maintenance and repair of the bronchiolar epithelium.

Stripp BR, Reynolds SD.

Proc Am Thorac Soc. 2008 Apr 15;5(3):328-33.PMID: 18403328 [PubMed - indexed for MEDLINE]Related articlesFree article

Conditional stabilization of beta-catenin expands the pool of lung stem cells.

Reynolds SD, Zemke AC, Giangreco A, Brockway BL, Teisanu RM, Drake JA, Mariani T, Di PY, Taketo MM, Stripp BR.

Stem Cells. 2008 May;26(5):1337-46. Epub 2008 Mar 20.PMID: 18356571 [PubMed - indexed for MEDLINE]Related articlesFree article

CCSP regulates cross talk between secretory cells and both ciliated cells and macrophages of the conducting airway.

Reynolds SD, Reynolds PR, Snyder JC, Whyte F, Paavola KJ, Stripp BR.

Am J Physiol Lung Cell Mol Physiol. 2007 Jul;293(1):L114-23. Epub 2007 Mar 23.PMID: 17384087 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular and functional properties of lung SP cells.

Reynolds SD, Shen H, Reynolds PR, Betsuyaku T, Pilewski JM, Gambelli F, Di Giuseppe M, Ortiz LA, Stripp BR.

Am J Physiol Lung Cell Mol Physiol. 2007 Apr;292(4):L972-83. Epub 2006 Dec 1. Erratum in: Am J Physiol Lung Cell Mol Physiol. 2007 Apr;292(3):L821. DeGuiseppe, Michelangelo [corrected to Di Giuseppe, Michelangelo]. PMID: 17142352 [PubMed - indexed for MEDLINE]Related articlesFree article

Stem cells in lung disease, repair, and the potential for therapeutic interventions: State-of-the-art and future challenges.

Stripp BR, Shapiro SD.

Am J Respir Cell Mol Biol. 2006 May;34(5):517-18. No abstract available. PMID: 16618784 [PubMed - indexed for MEDLINE]Related articlesFree article

Elevation of susceptibility to ozone-induced acute tracheobronchial injury in transgenic mice deficient in Clara cell secretory protein.

Plopper CG, Mango GW, Hatch GE, Wong VJ, Toskala E, Reynolds SD, Tarkington BK, Stripp BR.

Toxicol Appl Pharmacol. 2006 May 15;213(1):74-85. Epub 2005 Oct 14.PMID: 16226776 [PubMed - indexed for MEDLINE]Related articles

Bioengineered lung epithelium: implications for basic and applied studies in lung tissue regeneration.

Stripp BR, Reynolds SD.

Am J Respir Cell Mol Biol. 2005 Feb;32(2):85-6. No abstract available. PMID: 15657173 [PubMed - indexed for MEDLINE]Related articlesFree article

Clara cell secretory protein and phospholipase A2 activity modulate acute ventilator-induced lung injury in mice.

Yoshikawa S, Miyahara T, Reynolds SD, Stripp BR, Anghelescu M, Eyal FG, Parker JC.

J Appl Physiol. 2005 Apr;98(4):1264-71. Epub 2004 Dec 17.PMID: 15608088 [PubMed - indexed for MEDLINE]Related articlesFree article

Airway injury in lung disease pathophysiology: selective depletion of airway stem and progenitor cell pools potentiates lung inflammation and alveolar dysfunction.

Reynolds SD, Giangreco A, Hong KU, McGrath KE, Ortiz LA, Stripp BR.

Am J Physiol Lung Cell Mol Physiol. 2004 Dec;287(6):L1256-65. Epub 2004 Aug 6.PMID: 15298853 [PubMed - indexed for MEDLINE]Related articlesFree article

Mucin is produced by clara cells in the proximal airways of antigen-challenged mice.

Evans CM, Williams OW, Tuvim MJ, Nigam R, Mixides GP, Blackburn MR, DeMayo FJ, Burns AR, Smith C, Reynolds SD, Stripp BR, Dickey BF.

Am J Respir Cell Mol Biol. 2004 Oct;31(4):382-94. Epub 2004 Jun 10.PMID: 15191915 [PubMed - indexed for MEDLINE]Related articlesFree article

Time and pressure dependence of transvascular Clara cell protein, albumin, and IgG transport during ventilator-induced lung injury in mice.

Yoshikawa S, King JA, Reynolds SD, Stripp BR, Parker JC.

Am J Physiol Lung Cell Mol Physiol. 2004 Mar;286(3):L604-12.PMID: 14761872 [PubMed - indexed for MEDLINE]Related articlesFree article

Basal cells are a multipotent progenitor capable of renewing the bronchial epithelium.

Hong KU, Reynolds SD, Watkins S, Fuchs E, Stripp BR.

Am J Pathol. 2004 Feb;164(2):577-88.PMID: 14742263 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular phenotype of airway side population cells.

Giangreco A, Shen H, Reynolds SD, Stripp BR.

Am J Physiol Lung Cell Mol Physiol. 2004 Apr;286(4):L624-30. Epub 2003 Aug 8.PMID: 12909587 [PubMed - indexed for MEDLINE]Related articlesFree article

In vivo differentiation potential of tracheal basal cells: evidence for multipotent and unipotent subpopulations.

Hong KU, Reynolds SD, Watkins S, Fuchs E, Stripp BR.

Am J Physiol Lung Cell Mol Physiol. 2004 Apr;286(4):L643-9. Epub 2003 Jul 18.PMID: 12871857 [PubMed - indexed for MEDLINE]Related articlesFree article

Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways.

Reynolds SD, Reynolds PR, Pryhuber GS, Finder JD, Stripp BR.

Am J Respir Crit Care Med. 2002 Dec 1;166(11):1498-509. Epub 2002 Aug 1.PMID: 12406855 [PubMed - indexed for MEDLINE]Related articlesFree article

Clara cell secretory protein deficiency alters clara cell secretory apparatus and the protein composition of airway lining fluid.

Stripp BR, Reynolds SD, Boe IM, Lund J, Power JH, Coppens JT, Wong V, Reynolds PR, Plopper CG.

Am J Respir Cell Mol Biol. 2002 Aug;27(2):170-8.PMID: 12151308 [PubMed - indexed for MEDLINE]Related articlesFree article

Terminal bronchioles harbor a unique airway stem cell population that localizes to the bronchoalveolar duct junction.

Giangreco A, Reynolds SD, Stripp BR.

Am J Pathol. 2002 Jul;161(1):173-82.PMID: 12107102 [PubMed - indexed for MEDLINE]Related articlesFree article

Altered lung gene expression in CCSP-null mice suggests immunoregulatory roles for Clara cells.

Watson TM, Reynolds SD, Mango GW, Boe IM, Lund J, Stripp BR.

Am J Physiol Lung Cell Mol Physiol. 2001 Dec;281(6):L1523-30.PMID: 11704549 [PubMed - indexed for MEDLINE]Related articlesFree article

Clara cell secretory protein-expressing cells of the airway neuroepithelial body microenvironment include a label-retaining subset and are critical for epithelial renewal after progenitor cell depletion.

Hong KU, Reynolds SD, Giangreco A, Hurley CM, Stripp BR.

Am J Respir Cell Mol Biol. 2001 Jun;24(6):671-81.PMID: 11415931 [PubMed - indexed for MEDLINE]Related articlesFree article

Phenotypic consequences of lung-specific inducible expression of FGF-3.

Zhao B, Chua SS, Burcin MM, Reynolds SD, Stripp BR, Edwards RA, Finegold MJ, Tsai SY, DeMayo FJ.

Proc Natl Acad Sci U S A. 2001 May 8;98(10):5898-903. Epub 2001 May 1.PMID: 11331772 [PubMed - indexed for MEDLINE]Related articlesFree article

Pulmonary phenotype of CCSP/UG deficient mice: a consequence of CCSP deficiency or altered Clara cell function?

Stripp BR, Reynolds SD, Plopper CG, Bøe IM, Lund J.

Ann N Y Acad Sci. 2000;923:202-9. Review.PMID: 11193758 [PubMed - indexed for MEDLINE]Related articles

Conditional clara cell ablation reveals a self-renewing progenitor function of pulmonary neuroendocrine cells.

Reynolds SD, Hong KU, Giangreco A, Mango GW, Guron C, Morimoto Y, Stripp BR.

Am J Physiol Lung Cell Mol Physiol. 2000 Jun;278(6):L1256-63.PMID: 10835332 [PubMed - indexed for MEDLINE]Related articlesFree article

Alteration of pulmonary neuroendocrine cells during epithelial repair of naphthalene-induced airway injury.

Peake JL, Reynolds SD, Stripp BR, Stephens KE, Pinkerton KE.

Am J Pathol. 2000 Jan;156(1):279-86.PMID: 10623676 [PubMed - indexed for MEDLINE]Related articlesFree article

Neuroepithelial bodies of pulmonary airways serve as a reservoir of progenitor cells capable of epithelial regeneration.

Reynolds SD, Giangreco A, Power JH, Stripp BR.

Am J Pathol. 2000 Jan;156(1):269-78.PMID: 10623675 [PubMed - indexed for MEDLINE]Related articlesFree article

Normal function and lack of fibronectin accumulation in kidneys of Clara cell secretory protein/uteroglobin deficient mice.

Reynolds SD, Mango GW, Gelein R, Bøe IM, Lund J, Stripp BR.

Am J Kidney Dis. 1999 Mar;33(3):541-51.PMID: 10070919 [PubMed - indexed for MEDLINE]Related articles

Inflammatory and antioxidant gene expression in C57BL/6J mice after lethal and sublethal ozone exposures.

Johnston CJ, Stripp BR, Reynolds SD, Avissar NE, Reed CK, Finkelstein JN.

Exp Lung Res. 1999 Jan-Feb;25(1):81-97.PMID: 10027081 [PubMed - indexed for MEDLINE]Related articles

Clara cell secretory protein-deficient mice differ from wild-type mice in inflammatory chemokine expression to oxygen and ozone, but not to endotoxin.

Johnston CJ, Finkelstein JN, Oberdörster G, Reynolds SD, Stripp BR.

Exp Lung Res. 1999 Jan-Feb;25(1):7-21.PMID: 10027076 [PubMed - indexed for MEDLINE]Related articles

Hyperoxia increases keratinocyte growth factor mRNA expression in neonatal rabbit lung.

Charafeddine L, D'Angio CT, Richards JL, Stripp BR, Finkelstein JN, Orlowski CC, LoMonaco MB, Paxhia A, Ryan RM.

Am J Physiol. 1999 Jan;276(1 Pt 1):L105-13.PMID: 9887062 [PubMed - indexed for MEDLINE]Related articlesFree article

Clara cell secretory protein decreases lung inflammation after acute virus infection.

Harrod KS, Mounday AD, Stripp BR, Whitsett JA.

Am J Physiol. 1998 Nov;275(5 Pt 1):L924-30.PMID: 9815110 [PubMed - indexed for MEDLINE]Related articlesFree article

Aryl hydrocarbon receptor activation in genital tubercle, palate, and other embryonic tissues in 2,3,7, 8-tetrachlorodibenzo-p-dioxin-responsive lacZ mice.

Willey JJ, Stripp BR, Baggs RB, Gasiewicz TA.

Toxicol Appl Pharmacol. 1998 Jul;151(1):33-44.PMID: 9705885 [PubMed - indexed for MEDLINE]Related articles

Clara cell secretory protein deficiency increases oxidant stress response in conducting airways.

Mango GW, Johnston CJ, Reynolds SD, Finkelstein JN, Plopper CG, Stripp BR.

Am J Physiol. 1998 Aug;275(2 Pt 1):L348-56.PMID: 9700096 [PubMed - indexed for MEDLINE]Related articlesFree article

Inflammatory and epithelial responses in mouse strains that differ in sensitivity to hyperoxic injury.

Johnston CJ, Stripp BR, Piedbeouf B, Wright TW, Mango GW, Reed CK, Finkelstein JN.

Exp Lung Res. 1998 Mar-Apr;24(2):189-202.PMID: 9555576 [PubMed - indexed for MEDLINE]Related articles

Exposure to hyperoxia induces p53 expression in mouse lung epithelium.

O'Reilly MA, Staversky RJ, Stripp BR, Finkelstein JN.

Am J Respir Cell Mol Biol. 1998 Jan;18(1):43-50.PMID: 9448044 [PubMed - indexed for MEDLINE]Related articlesFree article

Epithelial-mesenchymal interactions in the alteration of gene expression and morphology following lung injury.

O'Reilly MA, Stripp BR, Pryhuber GS.

Microsc Res Tech. 1997 Sep 1;38(5):473-9. Review.PMID: 9376650 [PubMed - indexed for MEDLINE]Related articles

Altered pulmonary response to hyperoxia in Clara cell secretory protein deficient mice.

Johnston CJ, Mango GW, Finkelstein JN, Stripp BR.

Am J Respir Cell Mol Biol. 1997 Aug;17(2):147-55.PMID: 9271302 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell proliferation contributes to PNEC hyperplasia after acute airway injury.

Stevens TP, McBride JT, Peake JL, Pinkerton KE, Stripp BR.

Am J Physiol. 1997 Mar;272(3 Pt 1):L486-93.PMID: 9124606 [PubMed - indexed for MEDLINE]Related articles

Regulation of Clara cell secretory protein gene transcription by thyroid transcription factor-1.

Zhang L, Whitsett JA, Stripp BR.

Biochim Biophys Acta. 1997 Feb 28;1350(3):359-67.PMID: 9061032 [PubMed - indexed for MEDLINE]Related articles

Clara cell secretory protein: a determinant of PCB bioaccumulation in mammals.

Stripp BR, Lund J, Mango GW, Doyen KC, Johnston C, Hultenby K, Nord M, Whitsett JA.

Am J Physiol. 1996 Oct;271(4 Pt 1):L656-64.PMID: 8897914 [PubMed - indexed for MEDLINE]Related articles

Altered surfactant function and structure in SP-A gene targeted mice.

Korfhagen TR, Bruno MD, Ross GF, Huelsman KM, Ikegami M, Jobe AH, Wert SE, Stripp BR, Morris RE, Glasser SW, Bachurski CJ, Iwamoto HS, Whitsett JA.

Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9594-9.PMID: 8790375 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasticity of airway cell proliferation and gene expression after acute naphthalene injury.

Stripp BR, Maxson K, Mera R, Singh G.

Am J Physiol. 1995 Dec;269(6 Pt 1):L791-9.PMID: 8572241 [PubMed - indexed for MEDLINE]Related articles

Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice.

Clark JC, Wert SE, Bachurski CJ, Stahlman MT, Stripp BR, Weaver TE, Whitsett JA.

Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7794-8.PMID: 7644495 [PubMed - indexed for MEDLINE]Related articlesFree article

Airway epithelial cell expression of interleukin-6 in transgenic mice. Uncoupling of airway inflammation and bronchial hyperreactivity.

DiCosmo BF, Geba GP, Picarella D, Elias JA, Rankin JA, Stripp BR, Whitsett JA, Flavell RA.

J Clin Invest. 1994 Nov;94(5):2028-35.PMID: 7962549 [PubMed - indexed for MEDLINE]Related articlesFree article