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    Results: 31

    1.

    Both G i and G o heterotrimeric G proteins are required to exert the full effect of norepinephrine on the beta-cell K ATP channel.

    Zhao Y, Fang Q, Straub SG, Sharp GW.

    J Biol Chem. 2008 Feb 29;283(9):5306-16. Epub 2007 Dec 27.PMID: 18162464 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    The inhibitors of protein acylation, cerulenin and tunicamycin, increase voltage-dependent Ca(2+) currents in the insulin-secreting INS 832/13 cell.

    Zhao Y, Sharp GW, Straub SG.

    Biochem Pharmacol. 2007 Jul 15;74(2):273-80. Epub 2007 Apr 19.PMID: 17548064 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Inhibitory role of Src family tyrosine kinases on Ca2+-dependent insulin release.

    Cheng H, Straub SG, Sharp GW.

    Am J Physiol Endocrinol Metab. 2007 Mar;292(3):E845-52. Epub 2006 Nov 22.PMID: 17122086 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Inhibition of insulin secretion by cerulenin might be due to impaired glucose metabolism.

    Straub SG, Sharp GW.

    Diabetes Metab Res Rev. 2007 Feb;23(2):146-51.PMID: 16705622 [PubMed - indexed for MEDLINE]Related articles

    5.

    Stimulation of insulin release by glucose is associated with an increase in the number of docked granules in the beta-cells of rat pancreatic islets.

    Straub SG, Shanmugam G, Sharp GW.

    Diabetes. 2004 Dec;53(12):3179-83.PMID: 15561948 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Massive augmentation of stimulated insulin secretion induced by fatty acid-free BSA in rat pancreatic islets.

    Straub SG, Sharp GW.

    Diabetes. 2004 Dec;53(12):3152-8.PMID: 15561945 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Anaplerotic input is sufficient to induce time-dependent potentiation of insulin release in rat pancreatic islets.

    Gunawardana SC, Liu YJ, Macdonald MJ, Straub SG, Sharp GW.

    Am J Physiol Endocrinol Metab. 2004 Nov;287(5):E828-33.PMID: 15475511 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Hypothesis: one rate-limiting step controls the magnitude of both phases of glucose-stimulated insulin secretion.

    Straub SG, Sharp GW.

    Am J Physiol Cell Physiol. 2004 Sep;287(3):C565-71. Review.PMID: 15308461 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Y-26763: ATP-sensitive K+ channel activation and the inhibition of insulin release from human pancreatic beta-cells.

    Cosgrove KE, Straub SG, Barnes PD, Chapman J, Sharp GW, Dunne MJ.

    Eur J Pharmacol. 2004 Feb 20;486(2):133-9.PMID: 14975702 [PubMed - indexed for MEDLINE]Related articles

    10.

    Activation of the KATP channel-independent signaling pathway by the nonhydrolyzable analog of leucine, BCH.

    Liu YJ, Cheng H, Drought H, MacDonald MJ, Sharp GW, Straub SG.

    Am J Physiol Endocrinol Metab. 2003 Aug;285(2):E380-9. Epub 2003 Apr 22.PMID: 12709398 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Protein acylation in the inhibition of insulin secretion by norepinephrine, somatostatin, galanin, and PGE2.

    Cheng H, Straub SG, Sharp GW.

    Am J Physiol Endocrinol Metab. 2003 Aug;285(2):E287-94. Epub 2003 Apr 8.PMID: 12684222 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Stimulation of insulin secretion by denatonium, one of the most bitter-tasting substances known.

    Straub SG, Mulvaney-Musa J, Yajima H, Weiland GA, Sharp GW.

    Diabetes. 2003 Feb;52(2):356-64.PMID: 12540608 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Glucose-stimulated signaling pathways in biphasic insulin secretion.

    Straub SG, Sharp GW.

    Diabetes Metab Res Rev. 2002 Nov-Dec;18(6):451-63. Review.PMID: 12469359 [PubMed - indexed for MEDLINE]Related articles

    14.

    Progesterone inhibits insulin secretion by a membrane delimited, non-genomic action.

    Straub SG, Sharp GW, Meglasson MD, De Souza CJ.

    Biosci Rep. 2001 Oct;21(5):653-66.PMID: 12168772 [PubMed - indexed for MEDLINE]Related articles

    15.

    Hyposmotic shock stimulates insulin secretion by two distinct mechanisms. Studies with the betaHC9 cell.

    Straub SG, Daniel S, Sharp GW.

    Am J Physiol Endocrinol Metab. 2002 May;282(5):E1070-6.PMID: 11934672 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    The effects of cerulenin, an inhibitor of protein acylation, on the two phases of glucose-stimulated insulin secretion.

    Straub SG, Yajima H, Komatsu M, Aizawa T, Sharp GW.

    Diabetes. 2002 Feb;51 Suppl 1:S91-5.PMID: 11815464 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Triggering and augmentation mechanisms, granule pools, and biphasic insulin secretion.

    Bratanova-Tochkova TK, Cheng H, Daniel S, Gunawardana S, Liu YJ, Mulvaney-Musa J, Schermerhorn T, Straub SG, Yajima H, Sharp GW.

    Diabetes. 2002 Feb;51 Suppl 1:S83-90. Review.PMID: 11815463 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Hyperinsulinism of infancy: the regulated release of insulin by KATP channel-independent pathways.

    Straub SG, Cosgrove KE, Ammälä C, Shepherd RM, O'Brien RE, Barnes PD, Kuchinski N, Chapman JC, Schaeppi M, Glaser B, Lindley KJ, Sharp GW, Aynsley-Green A, Dunne MJ.

    Diabetes. 2001 Feb;50(2):329-39.PMID: 11272144 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Cerulenin, an inhibitor of protein acylation, selectively attenuates nutrient stimulation of insulin release: a study in rat pancreatic islets.

    Yajima H, Komatsu M, Yamada S, Straub SG, Kaneko T, Sato Y, Yamauchi K, Hashizume K, Sharp GW, Aizawa T.

    Diabetes. 2000 May;49(5):712-7.PMID: 10905478 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    The calcimimetic R-467 potentiates insulin secretion in pancreatic beta cells by activation of a nonspecific cation channel.

    Straub SG, Kornreich B, Oswald RE, Nemeth EF, Sharp GW.

    J Biol Chem. 2000 Jun 23;275(25):18777-84.PMID: 10751384 [PubMed - indexed for MEDLINE]Related articlesFree article

    21.

    Identification of the docked granule pool responsible for the first phase of glucose-stimulated insulin secretion.

    Daniel S, Noda M, Straub SG, Sharp GW.

    Diabetes. 1999 Sep;48(9):1686-90.PMID: 10480595 [PubMed - indexed for MEDLINE]Related articlesFree article

    22.

    Glucose augmentation of mastoparan-stimulated insulin secretion in rat and human pancreatic islets.

    Straub SG, James RF, Dunne MJ, Sharp GW.

    Diabetes. 1998 Jul;47(7):1053-7.PMID: 9648828 [PubMed - indexed for MEDLINE]Related articlesFree article

    23.

    Glucose activates both K(ATP) channel-dependent and K(ATP) channel-independent signaling pathways in human islets.

    Straub SG, James RF, Dunne MJ, Sharp GW.

    Diabetes. 1998 May;47(5):758-63.PMID: 9588447 [PubMed - indexed for MEDLINE]Related articlesFree article

    24.

    Augmentation of insulin release by glucose in the absence of extracellular Ca2+: new insights into stimulus-secretion coupling.

    Komatsu M, Schermerhorn T, Noda M, Straub SG, Aizawa T, Sharp GW.

    Diabetes. 1997 Dec;46(12):1928-38. Review.PMID: 9392476 [PubMed - indexed for MEDLINE]Related articles

    25.

    The alpha2-adrenergic receptor is more effective than the galanin receptor in activating G-proteins in RINm5F beta-cell membranes.

    Gillison SL, Straub SG, Sharp GW.

    Diabetes. 1997 Mar;46(3):401-7.PMID: 9032095 [PubMed - indexed for MEDLINE]Related articles

    26.

    Mechanisms of action of VIP and PACAP in the stimulation of insulin release.

    Straub SG, Sharp GW.

    Ann N Y Acad Sci. 1996 Dec 26;805:607-12.PMID: 8993448 [PubMed - indexed for MEDLINE]Related articles

    27.

    Pituitary adenylate cyclase-activating peptide, carbachol, and glucose stimulate insulin release in the absence of an increase in intracellular Ca2+.

    Komatsu M, Schermerhorn T, Straub SG, Sharp GW.

    Mol Pharmacol. 1996 Oct;50(4):1047-54.PMID: 8863853 [PubMed - indexed for MEDLINE]Related articles

    28.

    Glucose-dependent insulinotropic polypeptide stimulates insulin secretion via increased cyclic AMP and [Ca2+]1 and a wortmannin-sensitive signalling pathway.

    Straub SG, Sharp GW.

    Biochem Biophys Res Commun. 1996 Jul 16;224(2):369-74.PMID: 8702397 [PubMed - indexed for MEDLINE]Related articles

    29.

    A wortmannin-sensitive signal transduction pathway is involved in the stimulation of insulin release by vasoactive intestinal polypeptide and pituitary adenylate cyclase-activating polypeptide.

    Straub SG, Sharp GW.

    J Biol Chem. 1996 Jan 19;271(3):1660-8.PMID: 8576167 [PubMed - indexed for MEDLINE]Related articlesFree article

    30.

    Vasoactive intestinal polypeptide-augmented insulin release: actions on ionic fluxes and electrical activity of mouse islets.

    Wahl MA, Straub SG, Ammon HP.

    Diabetologia. 1993 Oct;36(10):920-5.PMID: 8243870 [PubMed - indexed for MEDLINE]Related articles

    31.

    Picomole analysis of alkali metals by flameless atomic absorption spectrophotometry.

    Wingo CS, Bixler GB, Park CH, Straub SG.

    Kidney Int. 1987 May;31(5):1225-8. No abstract available. Erratum in: Arch Dermatol 1987 Aug;123(8):994. PMID: 3599661 [PubMed - indexed for MEDLINE]Related articles

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