PubMed

ACTH-Independent Cushing's Syndrome with Bilateral Micronodular Adrenal Hyperplasia and Ectopic Adrenocortical Adenoma.

Louiset E, Gobet F, Libé R, Horvath A, Renouf S, Cariou J, Rothenbuhler A, Bertherat J, Clauser E, Grise P, Stratakis CA, Kuhn JM, Lefebvre H.

J Clin Endocrinol Metab. 2009 Nov 13. [Epub ahead of print]PMID: 19915020 [PubMed - as supplied by publisher]Related articles

Association of the M1V PRKAR1A Mutation with Primary Pigmented Nodular Adrenocortical Disease in Two Large Families.

Pereira AM, Hes FJ, Horvath A, Woortman S, Greene E, Bimpaki E, Alatsatianos A, Boikos S, Smit JW, Romijn JA, Nesterova M, Stratakis CA.

J Clin Endocrinol Metab. 2009 Nov 13. [Epub ahead of print]PMID: 19915019 [PubMed - as supplied by publisher]Related articles

MicroRNA signature in massive macronodular adrenocortical disease and implications for adrenocortical tumorigenesis.

Bimpaki EI, Iliopoulos D, Moraitis A, Stratakis CA.

Clin Endocrinol (Oxf). 2009 Oct 22. [Epub ahead of print]PMID: 19849700 [PubMed - as supplied by publisher]Related articles

Juvenile xanthogranuloma in a child with previously unsuspected neurofibromatosis type 1 and juvenile myelomonocytic leukemia.

Raygada M, Arthur DC, Wayne AS, Rennert OM, Toretsky JA, Stratakis CA.

Pediatr Blood Cancer. 2010 Jan;54(1):173-5.PMID: 19785027 [PubMed - in process]Related articles

8-Cl-adenosine inhibits proliferation and causes apoptosis in B-lymphocytes via protein kinase A-dependent and independent effects: implications for treatment of Carney complex-associated tumors.

Robinson-White AJ, Bossis I, Hsiao HP, Nesterova M, Leitner WW, Stratakis CA.

J Clin Endocrinol Metab. 2009 Oct;94(10):4061-9. Epub 2009 Sep 22.PMID: 19773399 [PubMed - indexed for MEDLINE]Related articles

Carney complex and lentiginosis.

Horvath A, Stratakis CA.

Pigment Cell Melanoma Res. 2009 Oct;22(5):580-7. Epub 2009 Jul 24. Review.PMID: 19650827 [PubMed - indexed for MEDLINE]Related articles

Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells.

Calado RT, Yewdell WT, Wilkerson KL, Regal JA, Kajigaya S, Stratakis CA, Young NS.

Blood. 2009 Sep 10;114(11):2236-43. Epub 2009 Jun 26.PMID: 19561322 [PubMed - indexed for MEDLINE]Related articles

Functional phosphodiesterase 11A mutations may modify the risk of familial and bilateral testicular germ cell tumors.

Horvath A, Korde L, Greene MH, Libe R, Osorio P, Faucz FR, Raffin-Sanson ML, Tsang KM, Drori-Herishanu L, Patronas Y, Remmers EF, Nikita ME, Moran J, Greene J, Nesterova M, Merino M, Bertherat J, Stratakis CA.

Cancer Res. 2009 Jul 1;69(13):5301-6. Epub 2009 Jun 23.PMID: 19549888 [PubMed - indexed for MEDLINE]Related articles

The triad of paragangliomas, gastric stromal tumours and pulmonary chondromas (Carney triad), and the dyad of paragangliomas and gastric stromal sarcomas (Carney-Stratakis syndrome): molecular genetics and clinical implications.

Stratakis CA, Carney JA.

J Intern Med. 2009 Jul;266(1):43-52. Review.PMID: 19522824 [PubMed - indexed for MEDLINE]Related articles

SDH mutations in tumorigenesis and inherited endocrine tumours: lesson from the phaeochromocytoma-paraganglioma syndromes.

Pasini B, Stratakis CA.

J Intern Med. 2009 Jul;266(1):19-42. Review.PMID: 19522823 [PubMed - indexed for MEDLINE]Related articles

Multiple endocrine neoplasias: advances and challenges for the future.

Alevizaki M, Stratakis CA.

J Intern Med. 2009 Jul;266(1):1-4.PMID: 19522821 [PubMed - indexed for MEDLINE]Related articles

Clinical and genetic heterogeneity, overlap with other tumor syndromes, and atypical glucocorticoid hormone secretion in adrenocorticotropin-independent macronodular adrenal hyperplasia compared with other adrenocortical tumors.

Hsiao HP, Kirschner LS, Bourdeau I, Keil MF, Boikos SA, Verma S, Robinson-White AJ, Nesterova M, Lacroix A, Stratakis CA.

J Clin Endocrinol Metab. 2009 Aug;94(8):2930-7. Epub 2009 Jun 9.PMID: 19509103 [PubMed - indexed for MEDLINE]Related articles

Postoperative testing to predict recurrent Cushing disease in children.

Batista DL, Oldfield EH, Keil MF, Stratakis CA.

J Clin Endocrinol Metab. 2009 Aug;94(8):2757-65. Epub 2009 May 26.PMID: 19470618 [PubMed - indexed for MEDLINE]Related articles

Abnormalities of cAMP signaling are present in adrenocortical lesions associated with ACTH-independent Cushing syndrome despite the absence of mutations in known genes.

Bimpaki EI, Nesterova M, Stratakis CA.

Eur J Endocrinol. 2009 Jul;161(1):153-61. Epub 2009 May 8.PMID: 19429701 [PubMed - indexed for MEDLINE]Related articles

Reversible posterior encephalopathy syndrome associated with micronodular adrenocortical disease and Cushing syndrome.

Lodish M, Patronas NJ, Stratakis CA.

Eur J Pediatr. 2010 Jan;169(1):125-6. Epub 2009 May 5.PMID: 19415327 [PubMed - in process]Related articles

Polymorphisms of the vitamin D receptor gene and stress fractures.

Chatzipapas C, Boikos S, Drosos GI, Kazakos K, Tripsianis G, Serbis A, Stergiopoulos S, Tilkeridis C, Verettas DA, Stratakis CA.

Horm Metab Res. 2009 Aug;41(8):635-40. Epub 2009 Apr 23.PMID: 19391078 [PubMed - indexed for MEDLINE]Related articles

An Intronic mutation is associated with prolactinoma in a young boy, decreased penetrance in his large family, and variable effects on MEN1 mRNA and protein.

Drori-Herishanu L, Horvath A, Nesterova M, Patronas Y, Lodish M, Bimpaki E, Patronas N, Agarwal S, Salvatori R, Martari M, Mericq V, Stratakis CA.

Horm Metab Res. 2009 Aug;41(8):630-4. Epub 2009 Apr 23.PMID: 19391077 [PubMed - indexed for MEDLINE]Related articles

The paradoxical increase in cortisol secretion induced by dexamethasone in primary pigmented nodular adrenocortical disease involves a glucocorticoid receptor-mediated effect of dexamethasone on protein kinase A catalytic subunits.

Louiset E, Stratakis CA, Perraudin V, Griffin KJ, Libé R, Cabrol S, Fève B, Young J, Groussin L, Bertherat J, Lefebvre H.

J Clin Endocrinol Metab. 2009 Jul;94(7):2406-13. Epub 2009 Apr 21.PMID: 19383776 [PubMed - indexed for MEDLINE]Related articles

MicroRNA signature of primary pigmented nodular adrenocortical disease: clinical correlations and regulation of Wnt signaling.

Iliopoulos D, Bimpaki EI, Nesterova M, Stratakis CA.

Cancer Res. 2009 Apr 15;69(8):3278-82. Epub 2009 Apr 7.PMID: 19351815 [PubMed - indexed for MEDLINE]Related articles

Facial metrics in children with corticotrophin-producing pituitary adenomas suggest abnormalities in midface development.

Keil MF, Stratakis CA.

J Pediatr Endocrinol Metab. 2009 Jan;22(1):47-53.PMID: 19344074 [PubMed - indexed for MEDLINE]Related articles

Mutations in regulatory subunit type 1A of cyclic adenosine 5'-monophosphate-dependent protein kinase (PRKAR1A): phenotype analysis in 353 patients and 80 different genotypes.

Bertherat J, Horvath A, Groussin L, Grabar S, Boikos S, Cazabat L, Libe R, René-Corail F, Stergiopoulos S, Bourdeau I, Bei T, Clauser E, Calender A, Kirschner LS, Bertagna X, Carney JA, Stratakis CA.

J Clin Endocrinol Metab. 2009 Jun;94(6):2085-91. Epub 2009 Mar 17.PMID: 19293268 [PubMed - indexed for MEDLINE]Related articles

Blood pressure in pediatric patients with Cushing syndrome.

Lodish MB, Sinaii N, Patronas N, Batista DL, Keil M, Samuel J, Moran J, Verma S, Popovic J, Stratakis CA.

J Clin Endocrinol Metab. 2009 Jun;94(6):2002-8. Epub 2009 Mar 17.PMID: 19293264 [PubMed - indexed for MEDLINE]Related articles

Mouse model for bilateral adrenal hyperplasia.

Sahut-Barnola I, De Joussineau C, Val P, Lambert-Langlais S, Lefrançois-Martinez AM, Pointud JC, Marceau G, Sapin V, Ragazzon B, Bertherat J, Kirschner LS, Stratakis CA, Martinez A.

Ann Endocrinol (Paris). 2009 Jun;70(3):194. Epub 2009 Mar 14. No abstract available. PMID: 19286161 [PubMed - indexed for MEDLINE]Related articles

Outcome of using the histological pseudocapsule as a surgical capsule in Cushing disease.

Jagannathan J, Smith R, DeVroom HL, Vortmeyer AO, Stratakis CA, Nieman LK, Oldfield EH.

J Neurosurg. 2009 Sep;111(3):531-9.PMID: 19267526 [PubMed - indexed for MEDLINE]Related articles

Ectopic thymus presenting as a thyroid nodule in a patient with the Carney complex.

Courcoutsakis N, Patronas N, Filie AC, Carney JA, Moraitis A, Stratakis CA.

Thyroid. 2009 Mar;19(3):293-6.PMID: 19265501 [PubMed - indexed for MEDLINE]Related articles

Short stature in partially corrected X-linked severe combined immunodeficiency--suboptimal response to growth hormone.

De Ravin SS, Shum E, Zarember KA, Rezvani G, Rosenfeld RG, Stratakis CA, Malech HL.

J Pediatr Endocrinol Metab. 2008 Nov;21(11):1057-63.PMID: 19189700 [PubMed - indexed for MEDLINE]Related articlesFree article

Quality of life in children and adolescents 1-year after cure of Cushing syndrome: a prospective study.

Keil MF, Merke DP, Gandhi R, Wiggs EA, Obunse K, Stratakis CA.

Clin Endocrinol (Oxf). 2009 Sep;71(3):326-33. Epub 2008 Dec 17.PMID: 19170709 [PubMed - indexed for MEDLINE]Related articlesFree article

Extensive and largely reversible ischemic cerebral infarctions in a prepubertal child with hypertension and Cushing disease.

Nguyen JH, Lodish MB, Patronas NJ, Ugrasbul F, Keil MF, Roberts MD, Popovic J, Stratakis CA.

J Clin Endocrinol Metab. 2009 Jan;94(1):1-2. No abstract available. PMID: 19126630 [PubMed - indexed for MEDLINE]Related articles

New genes and/or molecular pathways associated with adrenal hyperplasias and related adrenocortical tumors.

Stratakis CA.

Mol Cell Endocrinol. 2009 Mar 5;300(1-2):152-7. Epub 2008 Nov 21. Review.PMID: 19063937 [PubMed - indexed for MEDLINE]Related articles

Altered amygdala and hippocampus function in adolescents with hypercortisolemia: a functional magnetic resonance imaging study of Cushing syndrome.

Maheu FS, Mazzone L, Merke DP, Keil MF, Stratakis CA, Pine DS, Ernst M.

Dev Psychopathol. 2008 Fall;20(4):1177-89.PMID: 18838037 [PubMed - indexed for MEDLINE]Related articles

Body image in adolescents with disorders of steroidogenesis.

Ning C, Green-Golan L, Stratakis CA, Leschek E, Sinaii N, Schroth E, Ernst M, Merke DP.

J Pediatr Endocrinol Metab. 2008 Aug;21(8):771-80.PMID: 18825877 [PubMed - indexed for MEDLINE]Related articles

Hypocalcemia in a patient with osteosarcoma and 22q11.2 deletion syndrome.

Mussai FJ, Cunningham LC, Rezvani G, Stratakis CA, Reynolds JC, Nesterova G, Henshaw RM, Levine JE, Helman LJ, Arthur DC, Kim SY.

J Pediatr Hematol Oncol. 2008 Aug;30(8):612-7.PMID: 18799940 [PubMed - indexed for MEDLINE]Related articlesFree article

Severe obesity confounds the interpretation of low-dose dexamethasone test combined with the administration of ovine corticotrophin-releasing hormone in childhood Cushing syndrome.

Batista DL, Courcoutsakis N, Riar J, Keil MF, Stratakis CA.

J Clin Endocrinol Metab. 2008 Nov;93(11):4323-30. Epub 2008 Aug 26.PMID: 18728165 [PubMed - indexed for MEDLINE]Related articlesFree article

The use of positron emission tomography-computed tomography scan in the evaluation of a patient with Carney complex.

Bandelin PB, Moreno AJ, Lemar HJ, Stratakis CA, Oliver TG.

J Clin Endocrinol Metab. 2008 Aug;93(8):2946-7. No abstract available. PMID: 18685116 [PubMed - indexed for MEDLINE]Related articlesFree article

Stromal, fibrous, and fatty gastrointestinal tumors in a patient with a PDGFRA gene mutation.

Carney JA, Stratakis CA.

Am J Surg Pathol. 2008 Sep;32(9):1412-20.PMID: 18670346 [PubMed - indexed for MEDLINE]Related articles

Selective loss of MEG3 expression and intergenic differentially methylated region hypermethylation in the MEG3/DLK1 locus in human clinically nonfunctioning pituitary adenomas.

Gejman R, Batista DL, Zhong Y, Zhou Y, Zhang X, Swearingen B, Stratakis CA, Hedley-Whyte ET, Klibanski A.

J Clin Endocrinol Metab. 2008 Oct;93(10):4119-25. Epub 2008 Jul 15.PMID: 18628527 [PubMed - indexed for MEDLINE]Related articlesFree article

Phosphodiesterase 11A (PDE11A) and genetic predisposition to adrenocortical tumors.

Libé R, Fratticci A, Coste J, Tissier F, Horvath A, Ragazzon B, Rene-Corail F, Groussin L, Bertagna X, Raffin-Sanson ML, Stratakis CA, Bertherat J.

Clin Cancer Res. 2008 Jun 15;14(12):4016-24.PMID: 18559625 [PubMed - indexed for MEDLINE]Related articlesFree article

Operative management of Cushing syndrome secondary to micronodular adrenal hyperplasia.

Powell AC, Stratakis CA, Patronas NJ, Steinberg SM, Batista D, Alexander HR, Pingpank JF, Keil M, Bartlett DL, Libutti SK.

Surgery. 2008 Jun;143(6):750-8.PMID: 18549891 [PubMed - indexed for MEDLINE]Related articlesFree article

Cushing syndrome caused by adrenocortical tumors and hyperplasias (corticotropin- independent Cushing syndrome).

Stratakis CA.

Endocr Dev. 2008;13:117-32. Review.PMID: 18493137 [PubMed - indexed for MEDLINE]Related articles

Phosphodiesterase 11A expression in the adrenal cortex, primary pigmented nodular adrenocortical disease, and other corticotropin-independent lesions.

Boikos SA, Horvath A, Heyerdahl S, Stein E, Robinson-White A, Bossis I, Bertherat J, Carney JA, Stratakis CA.

Horm Metab Res. 2008 May;40(5):347-53.PMID: 18491255 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors.

Meoli E, Bossis I, Cazabat L, Mavrakis M, Horvath A, Stergiopoulos S, Shiferaw ML, Fumey G, Perlemoine K, Muchow M, Robinson-White A, Weinberg F, Nesterova M, Patronas Y, Groussin L, Bertherat J, Stratakis CA.

Cancer Res. 2008 May 1;68(9):3133-41.PMID: 18451138 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel PRKAR1A mutation associated with hepatocellular carcinoma in a young patient and a variable Carney complex phenotype in affected subjects in older generations.

Gennari M, Stratakis CA, Hovarth A, Pirazzoli P, Cicognani A.

Clin Endocrinol (Oxf). 2008 Nov;69(5):751-5. Epub 2008 Apr 28.PMID: 18445140 [PubMed - indexed for MEDLINE]Related articles

Unraveling the molecular basis of micronodular adrenal hyperplasia.

Horvath A, Stratakis CA.

Curr Opin Endocrinol Diabetes Obes. 2008 Jun;15(3):227-33. Review.PMID: 18438169 [PubMed - indexed for MEDLINE]Related articlesFree article

A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex.

Horvath A, Giatzakis C, Tsang K, Greene E, Osorio P, Boikos S, Libè R, Patronas Y, Robinson-White A, Remmers E, Bertherat J, Nesterova M, Stratakis CA.

Eur J Hum Genet. 2008 Oct;16(10):1245-53. Epub 2008 Apr 23.PMID: 18431404 [PubMed - indexed for MEDLINE]Related articlesFree article

How the new tools to analyze the human genome are opening new perspectives: the use of gene expression in investigations of the adrenal cortex.

Stratakis CA, Horvath A.

Ann Endocrinol (Paris). 2008 Apr;69(2):123-9. Epub 2008 Apr 18. Review.PMID: 18423555 [PubMed - indexed for MEDLINE]Related articlesFree article

Detection of somatic beta-catenin mutations in primary pigmented nodular adrenocortical disease (PPNAD).

Tadjine M, Lampron A, Ouadi L, Horvath A, Stratakis CA, Bourdeau I.

Clin Endocrinol (Oxf). 2008 Sep;69(3):367-73. Epub 2008 Apr 14.PMID: 18419788 [PubMed - indexed for MEDLINE]Related articles

Pituitary tumors in childhood: update of diagnosis, treatment and molecular genetics.

Keil MF, Stratakis CA.

Expert Rev Neurother. 2008 Apr;8(4):563-74. Review.PMID: 18416659 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition.

Nadella KS, Jones GN, Trimboli A, Stratakis CA, Leone G, Kirschner LS.

Cancer Res. 2008 Apr 15;68(8):2671-7.PMID: 18413734 [PubMed - indexed for MEDLINE]Related articlesFree article

RET oncogene in MEN2, MEN2B, MTC and other forms of thyroid cancer.

Lodish MB, Stratakis CA.

Expert Rev Anticancer Ther. 2008 Apr;8(4):625-32. Review.PMID: 18402529 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase A subunit expression is altered in Bloom syndrome fibroblasts and the BLM protein is increased in adrenocortical hyperplasias: inverse findings for BLM and PRKAR1A.

Heyerdahl SL, Boikos S, Horvath A, Giatzakis C, Bossis I, Stratakis CA.

Horm Metab Res. 2008 Jun;40(6):391-7. Epub 2008 Mar 6.PMID: 18401830 [PubMed - indexed for MEDLINE]Related articles