PubMed

Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection.

Doan T, McNally A, Thomas R, Steptoe RJ.

Immunol Cell Biol. 2009 Nov-Dec;87(8):615-22. Epub 2009 Jul 7.PMID: 19581919 [PubMed - in process]Related articles

Dendritic cells in the thymus contribute to T-regulatory cell induction.

Proietto AI, van Dommelen S, Zhou P, Rizzitelli A, D'Amico A, Steptoe RJ, Naik SH, Lahoud MH, Liu Y, Zheng P, Shortman K, Wu L.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19869-74. Epub 2008 Dec 10. Erratum in: Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1679. PMID: 19073916 [PubMed - indexed for MEDLINE]Related articlesFree article

Steady-state dendritic cells expressing cognate antigen terminate memory CD8+ T-cell responses.

Kenna TJ, Thomas R, Steptoe RJ.

Blood. 2008 Feb 15;111(4):2091-100. Epub 2007 Nov 14.PMID: 18003887 [PubMed - indexed for MEDLINE]Related articlesFree article

Cognate CD4+ help elicited by resting dendritic cells does not impair the induction of peripheral tolerance in CD8+ T cells.

Steptoe RJ, Ritchie JM, Wilson NS, Villadangos JA, Lew AM, Harrison LC.

J Immunol. 2007 Feb 15;178(4):2094-103.PMID: 17277113 [PubMed - indexed for MEDLINE]Related articlesFree article

Proinsulin is encoded by an RNA splice variant in human blood myeloid cells.

Narendran P, Neale AM, Lee BH, Ngui K, Steptoe RJ, Morahan G, Madsen O, Dromey JA, Jensen KP, Harrison LC.

Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16430-5. Epub 2006 Oct 19.PMID: 17053071 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-1 beta breaks tolerance through expansion of CD25+ effector T cells.

O'Sullivan BJ, Thomas HE, Pai S, Santamaria P, Iwakura Y, Steptoe RJ, Kay TW, Thomas R.

J Immunol. 2006 Jun 15;176(12):7278-87.PMID: 16751371 [PubMed - indexed for MEDLINE]Related articlesFree article

Systemic activation of dendritic cells by Toll-like receptor ligands or malaria infection impairs cross-presentation and antiviral immunity.

Wilson NS, Behrens GM, Lundie RJ, Smith CM, Waithman J, Young L, Forehan SP, Mount A, Steptoe RJ, Shortman KD, de Koning-Ward TF, Belz GT, Carbone FR, Crabb BS, Heath WR, Villadangos JA.

Nat Immunol. 2006 Feb;7(2):165-72. Epub 2006 Jan 15.PMID: 16415871 [PubMed - indexed for MEDLINE]Related articles

Autoimmune diabetes is suppressed by transfer of proinsulin-encoding Gr-1+ myeloid progenitor cells that differentiate in vivo into resting dendritic cells.

Steptoe RJ, Ritchie JM, Jones LK, Harrison LC.

Diabetes. 2005 Feb;54(2):434-42.PMID: 15677501 [PubMed - indexed for MEDLINE]Related articlesFree article

Persistence of recipient lymphocytes in NOD mice after irradiation and bone marrow transplantation.

Steptoe RJ, Stankovic S, Lopaticki S, Jones LK, Harrison LC, Morahan G.

J Autoimmun. 2004 Mar;22(2):131-8.PMID: 14987741 [PubMed - indexed for MEDLINE]Related articles

The protease inhibitor cystatin C is differentially expressed among dendritic cell populations, but does not control antigen presentation.

El-Sukkari D, Wilson NS, Hakansson K, Steptoe RJ, Grubb A, Shortman K, Villadangos JA.

J Immunol. 2003 Nov 15;171(10):5003-11.PMID: 14607896 [PubMed - indexed for MEDLINE]Related articlesFree article

Most lymphoid organ dendritic cell types are phenotypically and functionally immature.

Wilson NS, El-Sukkari D, Belz GT, Smith CM, Steptoe RJ, Heath WR, Shortman K, Villadangos JA.

Blood. 2003 Sep 15;102(6):2187-94. Epub 2003 Jun 5.PMID: 12791652 [PubMed - indexed for MEDLINE]Related articlesFree article

Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.

Steptoe RJ, Ritchie JM, Harrison LC.

J Clin Invest. 2003 May;111(9):1357-63.PMID: 12727927 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased generation of dendritic cells from myeloid progenitors in autoimmune-prone nonobese diabetic mice.

Steptoe RJ, Ritchie JM, Harrison LC.

J Immunol. 2002 May 15;168(10):5032-41.PMID: 11994455 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunobiology of liver dendritic cells.

Thomson AW, O'Connell PJ, Steptoe RJ, Lu L.

Immunol Cell Biol. 2002 Feb;80(1):65-73. Review.PMID: 11881616 [PubMed - indexed for MEDLINE]Related articlesFree article

MHC class II expression is regulated in dendritic cells independently of invariant chain degradation.

Villadangos JA, Cardoso M, Steptoe RJ, van Berkel D, Pooley J, Carbone FR, Shortman K.

Immunity. 2001 Jun;14(6):739-49.PMID: 11420044 [PubMed - indexed for MEDLINE]Related articles

Resident tissue macrophages within the normal rat iris lack immunosuppressive activity and are effective antigen-presenting cells.

Steptoe RJ, McMenamin PG, Holt PG.

Ocul Immunol Inflamm. 2000 Sep;8(3):177-87.PMID: 11120579 [PubMed - indexed for MEDLINE]Related articles

Comparative analysis of dendritic cell density and total number in commonly transplanted organs: morphometric estimation in normal mice.

Steptoe RJ, Patel RK, Subbotin VM, Thomson AW.

Transpl Immunol. 2000 Mar;8(1):49-56.PMID: 10834610 [PubMed - indexed for MEDLINE]Related articles

Hepatic dendritic cells: immunobiology and role in liver transplantation.

Thomson AW, Drakes ML, Zahorchak AF, O'Connell PJ, Steptoe RJ, Qian S, Lu L.

J Leukoc Biol. 1999 Aug;66(2):322-30. Review.PMID: 10449176 [PubMed - indexed for MEDLINE]Related articlesFree article

Trafficking of APC from liver allografts of Flt3L-treated donors: augmentation of potent allostimulatory cells in recipient lymphoid tissue is associated with a switch from tolerance to rejection.

Steptoe RJ, Li W, Fu F, O'Connell PJ, Thomson AW.

Transpl Immunol. 1999 Mar;7(1):51-7.PMID: 10375078 [PubMed - indexed for MEDLINE]Related articles

Impact of Flt-3 ligand on donor-derived antigen presenting cells and alloimmune reactivity in heart graft recipients given adjuvant donor bone marrow.

Khanna A, Antonysamy MA, Subbotin VM, Steptoe RJ, Li W, Rudert WA, Thomson AW.

Transpl Immunol. 1998 Dec;6(4):225-34.PMID: 10342736 [PubMed - indexed for MEDLINE]Related articles

Expansion of functional NK cells in multiple tissue compartments of mice treated with Flt3-ligand: implications for anti-cancer and anti-viral therapy.

Shaw SG, Maung AA, Steptoe RJ, Thomson AW, Vujanovic NL.

J Immunol. 1998 Sep 15;161(6):2817-24.PMID: 9743341 [PubMed - indexed for MEDLINE]Related articlesFree article

Donor pretreatment with Flt-3 ligand augments antidonor cytotoxic T lymphocyte, natural killer, and lymphokine-activated killer cell activities within liver allografts and alters the pattern of intragraft apoptotic activity.

Qian S, Lu L, Fu F, Li W, Pan F, Steptoe RJ, Chambers FG, Starzl TE, Fung JJ, Thomson AW.

Transplantation. 1998 Jun 27;65(12):1590-8.PMID: 9665075 [PubMed - indexed for MEDLINE]Related articles

Flt-3 ligand increases microchimerism but can prevent the therapeutic effect of donor bone marrow in transiently immunosuppressed cardiac allograft recipients.

Antonysamy MA, Steptoe RJ, Khanna A, Rudert WA, Subbotin VM, Thomson AW.

J Immunol. 1998 Apr 15;160(8):4106-13.PMID: 9558122 [PubMed - indexed for MEDLINE]Related articlesFree article

Augmentation of dendritic cells in murine organ donors by Flt3 ligand alters the balance between transplant tolerance and immunity.

Steptoe RJ, Fu F, Li W, Drakes ML, Lu L, Demetris AJ, Qian S, McKenna HJ, Thomson AW.

J Immunol. 1997 Dec 1;159(11):5483-91.PMID: 9548488 [PubMed - indexed for MEDLINE]Related articles

Donor bone marrow potentiates the effect of tacrolimus on nonvascularized heart allograft survival: association with microchimerism and growth of donor dendritic cell progenitors from recipient bone marrow.

Khanna A, Steptoe RJ, Antonysamy MA, Li W, Thomson AW.

Transplantation. 1998 Feb 27;65(4):479-85.PMID: 9500620 [PubMed - indexed for MEDLINE]Related articles

Major histocompatibility complex (MHC) class II--positive dendritic cells in the rat iris. In situ development from MHC class II-negative precursors.

Steptoe RJ, Holt PG, McMenamin PG.

Invest Ophthalmol Vis Sci. 1997 Nov;38(12):2639-48.PMID: 9375583 [PubMed - indexed for MEDLINE]Related articlesFree article

Dendritic cells and tolerance induction.

Steptoe RJ, Thomson AW.

Clin Exp Immunol. 1996 Sep;105(3):397-402. Review.PMID: 8809125 [PubMed - indexed for MEDLINE]Related articlesFree article

Origin and steady-state turnover of major histocompatibility complex class II-positive dendritic cells and resident-tissue macrophages in the iris of the rat eye.

Steptoe RJ, Holt PG, McMenamin PG.

J Neuroimmunol. 1996 Aug;68(1-2):67-76.PMID: 8784262 [PubMed - indexed for MEDLINE]Related articles

Functional studies of major histocompatibility class II-positive dendritic cells and resident tissue macrophages isolated from the rat iris.

Steptoe RJ, Holt PG, McMenamin PG.

Immunology. 1995 Aug;85(4):630-7.PMID: 7558159 [PubMed - indexed for MEDLINE]Related articlesFree article

Distribution and characterisation of rat choroidal mast cells.

Steptoe RJ, McMenamin PG, McMenamin C.

Br J Ophthalmol. 1994 Mar;78(3):211-8.PMID: 8148338 [PubMed - indexed for MEDLINE]Related articlesFree article

Ultrastructural pathology of experimental autoimmune uveitis. Quantitative evidence of activation and possible high endothelial venule-like changes in retinal vascular endothelium.

McMenamin PG, Forrester JV, Steptoe RJ, Dua HS.

Lab Invest. 1992 Jul;67(1):42-55.PMID: 1625447 [PubMed - indexed for MEDLINE]Related articles

Normal anatomy of the aqueous humour outflow system in the domestic pig eye.

McMenamin PG, Steptoe RJ.

J Anat. 1991 Oct;178:65-77.PMID: 1810936 [PubMed - indexed for MEDLINE]Related articlesFree article