PubMed

Cytotoxicity of methoctramine and methoctramine-related polyamines.

Zini M, Passariello CL, Gottardi D, Cetrullo S, Flamigni F, Pignatti C, Minarini A, Tumiatti V, Milelli A, Melchiorre C, Stefanelli C.

Chem Biol Interact. 2009 Oct 30;181(3):409-16. Epub 2009 Jul 1.PMID: 19576191 [PubMed - indexed for MEDLINE]Related articles

Adrenocortical response in infants undergoing cardiac surgery with cardiopulmonary bypass and circulatory arrest.

Gajarski RJ, Stefanelli CB, Graziano JN, Kaciroti N, Charpie JR, Vazquez D.

Pediatr Crit Care Med. 2009 May 15. [Epub ahead of print]PMID: 19451847 [PubMed - as supplied by publisher]Related articles

The polyamine analogue N1,N11-diethylnorspermine can induce chondrocyte apoptosis independently of its ability to alter metabolism and levels of natural polyamines.

Stanic' I, Facchini A, Borzì RM, Stefanelli C, Flamigni F.

J Cell Physiol. 2009 Apr;219(1):109-16.PMID: 19097065 [PubMed - indexed for MEDLINE]Related articles

Antitumor activity of new substituted 3-(5-imidazo[2,1-b]thiazolylmethylene)-2-indolinones and 3-(5-imidazo[2,1-b]thiadiazolylmethylene)-2-indolinones: selectivity against colon tumor cells and effect on cell cycle-related events.

Andreani A, Burnelli S, Granaiola M, Leoni A, Locatelli A, Morigi R, Rambaldi M, Varoli L, Calonghi N, Cappadone C, Voltattorni M, Zini M, Stefanelli C, Masotti L, Shoemaker RH.

J Med Chem. 2008 Dec 11;51(23):7508-13.PMID: 19006285 [PubMed - indexed for MEDLINE]Related articles

New antitumor imidazo[2,1-b]thiazole guanylhydrazones and analogues.

Andreani A, Burnelli S, Granaiola M, Leoni A, Locatelli A, Morigi R, Rambaldi M, Varoli L, Calonghi N, Cappadone C, Farruggia G, Zini M, Stefanelli C, Masotti L, Radin NS, Shoemaker RH.

J Med Chem. 2008 Feb 28;51(4):809-16. Epub 2008 Feb 6.PMID: 18251494 [PubMed - indexed for MEDLINE]Related articles

Effect of the polyamine analogue N1,N11-diethylnorspermine on cell survival and susceptibility to apoptosis of human chondrocytes.

Stanic I, Cetrullo S, Facchini A, Stefanelli C, Borzì RM, Tantini B, Guarnieri C, Caldarera CM, Flamigni F.

J Cell Physiol. 2008 Jul;216(1):153-61.PMID: 18231987 [PubMed - indexed for MEDLINE]Related articles

Substituted E-3-(2-chloro-3-indolylmethylene)1,3-dihydroindol-2-ones with antitumor activity. Effect on the cell cycle and apoptosis.

Andreani A, Burnelli S, Granaiola M, Leoni A, Locatelli A, Morigi R, Rambaldi M, Varoli L, Calonghi N, Cappadone C, Farruggia G, Zini M, Stefanelli C, Masotti L.

J Med Chem. 2007 Jul 12;50(14):3167-72. Epub 2007 Jun 9.PMID: 17559205 [PubMed - indexed for MEDLINE]Related articles

Synthesis and antitumor activity of guanylhydrazones from 6-(2,4-dichloro-5-nitrophenyl)imidazo[2,1-b]thiazoles and 6-pyridylimidazo[2,1-b]thiazoles(1).

Andreani A, Burnelli S, Granaiola M, Leoni A, Locatelli A, Morigi R, Rambaldi M, Varoli L, Farruggia G, Stefanelli C, Masotti L, Kunkel MW.

J Med Chem. 2006 Dec 28;49(26):7897-901.PMID: 17181173 [PubMed - indexed for MEDLINE]Related articles

Involvement of polyamines in apoptosis of cardiac myoblasts in a model of simulated ischemia.

Tantini B, Fiumana E, Cetrullo S, Pignatti C, Bonavita F, Shantz LM, Giordano E, Muscari C, Flamigni F, Guarnieri C, Stefanelli C, Caldarera CM.

J Mol Cell Cardiol. 2006 Jun;40(6):775-82. Epub 2006 May 5.PMID: 16678846 [PubMed - indexed for MEDLINE]Related articles

Polyamine depletion inhibits apoptosis following blocking of survival pathways in human chondrocytes stimulated by tumor necrosis factor-alpha.

Stanic I, Facchini A, Borzì RM, Vitellozzi R, Stefanelli C, Goldring MB, Guarnieri C, Facchini A, Flamigni F.

J Cell Physiol. 2006 Jan;206(1):138-46.PMID: 15965903 [PubMed - indexed for MEDLINE]Related articles

Polyamine depletion reduces TNFalpha/MG132-induced apoptosis in bone marrow stromal cells.

Muscari C, Bonafé F, Stanic I, Flamigni F, Stefanelli C, Farruggia G, Guarnieri C, Caldarera CM.

Stem Cells. 2005 Aug;23(7):983-91. Epub 2005 Jun 7.PMID: 15941855 [PubMed - indexed for MEDLINE]Related articlesFree article

Polyamine depletion inhibits NF-kappaB binding to DNA and interleukin-8 production in human chondrocytes stimulated by tumor necrosis factor-alpha.

Facchini A, Borzí RM, Marcu KB, Stefanelli C, Olivotto E, Goldring MB, Facchini A, Flamigni F.

J Cell Physiol. 2005 Sep;204(3):956-63.PMID: 15828019 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel troponin T mutation in familial dilated cardiomyopathy with gender-dependant severity.

Stefanelli CB, Rosenthal A, Borisov AB, Ensing GJ, Russell MW.

Mol Genet Metab. 2004 Sep-Oct;83(1-2):188-96.PMID: 15464434 [PubMed - indexed for MEDLINE]Related articles

Signal transduction pathways linking polyamines to apoptosis.

Pignatti C, Tantini B, Stefanelli C, Flamigni F.

Amino Acids. 2004 Dec;27(3-4):359-65. Epub 2004 Sep 29. Review.PMID: 15452702 [PubMed - indexed for MEDLINE]Related articles

Polyamine depletion inhibits etoposide-induced NF-kappaB activation in transformed mouse fibroblasts.

Tantini B, Pignatti C, Fattori M, Fiumana E, Facchini A, Stefanelli C, Caldarera CM, Pegg AE, Flamigni F.

Amino Acids. 2004 Oct;27(2):207-14. Epub 2004 Sep 22.PMID: 15378410 [PubMed - indexed for MEDLINE]Related articles

Membrane binding and transport of N-aminoethyl-1,2-diamino ethane (dien) and N-aminopropyl-1,3-diamino propane (propen) by rat liver mitochondria and their effects on membrane permeability transition.

Dalla Via L, Salvi M, Di Noto V, Stefanelli C, Toninello A.

Mol Membr Biol. 2004 Mar-Apr;21(2):109-18.PMID: 15204440 [PubMed - indexed for MEDLINE]Related articles

Effect of green tea extract on the induction of ornithine decarboxylase and the activation of extracellular signal-regulated kinase in bladder carcinoma ECV304 cells.

Facchini A, Zanella B, Stefanelli C, Guarnieri C, Flamigni F.

Nutr Cancer. 2003;47(1):104-10.PMID: 14769544 [PubMed - indexed for MEDLINE]Related articles

Transtelephonic electrocardiographic monitors for evaluation of children and adolescents with suspected arrhythmias.

Saarel EV, Stefanelli CB, Fischbach PS, Serwer GA, Rosenthal A, Dick M 2nd.

Pediatrics. 2004 Feb;113(2):248-51.PMID: 14754934 [PubMed - indexed for MEDLINE]Related articlesFree article

Ischemia/reperfusion-induced apoptosis: connecting nitric oxide and cell cycle regulators.

Pignatti C, Stefanelli C.

Cardiovasc Res. 2003 Aug 1;59(2):268-70. No abstract available. PMID: 12909309 [PubMed - indexed for MEDLINE]Related articlesFree article

H9c2 cardiac myoblasts undergo apoptosis in a model of ischemia consisting of serum deprivation and hypoxia: inhibition by PMA.

Bonavita F, Stefanelli C, Giordano E, Columbaro M, Facchini A, Bonafè F, Caldarera CM, Guarnieri C.

FEBS Lett. 2003 Feb 11;536(1-3):85-91.PMID: 12586343 [PubMed - indexed for MEDLINE]Related articles

Caspase activation in etoposide-treated fibroblasts is correlated to ERK phosphorylation and both events are blocked by polyamine depletion.

Stefanelli C, Tantini B, Fattori M, Stanic' I, Pignatti C, Clo C, Guarnieri C, Caldarera CM, Mackintosh CA, Pegg AE, Flamigni F.

FEBS Lett. 2002 Sep 11;527(1-3):223-28.PMID: 12220664 [PubMed - indexed for MEDLINE]Related articles

Implantable cardioverter defibrillator therapy for life-threatening arrhythmias in young patients.

Stefanelli CB, Bradley DJ, Leroy S, Dick M 2nd, Serwer GA, Fischbach PS.

J Interv Card Electrophysiol. 2002 Jul;6(3):235-44.PMID: 12154326 [PubMed - indexed for MEDLINE]Related articles

Evidence of oxidative imbalance in long-term liver transplant patients.

Trevisani F, Caraceni P, Simoncini M, Micati M, Domenicali M, Dazzani F, Zambruni A, Stefanelli C, Grazi G, Nardo B, Guarnieri C, Bernardi M.

Dig Liver Dis. 2002 Apr;34(4):279-84.PMID: 12038812 [PubMed - indexed for MEDLINE]Related articles

Effect of actinomycin D on simian rotavirus (SA11) replication in cell culture.

Stefanelli CC, Castilho JG, Botelho MV, Linhares RE, Nozawa CM.

Braz J Med Biol Res. 2002 Apr;35(4):445-9.PMID: 11960193 [PubMed - indexed for MEDLINE]Related articlesFree article

NF-kappaB and ERK cooperate to stimulate DNA synthesis by inducing ornithine decarboxylase and nitric oxide synthase in cardiomyocytes treated with TNF and LPS.

Tantini B, Pignatti C, Fattori M, Flamigni F, Stefanelli C, Giordano E, Menegazzi M, Clô C, Caldarera CM.

FEBS Lett. 2002 Feb 13;512(1-3):75-9.PMID: 11852055 [PubMed - indexed for MEDLINE]Related articles

Control of survival of proliferating L1210 cells by soluble guanylate cyclase and p44/42 mitogen-activated protein kinase modulators.

Flamigni F, Facchini A, Stanic I, Tantini B, Bonavita F, Stefanelli C.

Biochem Pharmacol. 2001 Aug 1;62(3):319-28.PMID: 11434904 [PubMed - indexed for MEDLINE]Related articles

Activation of acetyl-CoA carboxylase by a glutamate- and magnesium-sensitive protein phosphatase in the islet beta-cell.

Kowluru A, Chen HQ, Modrick LM, Stefanelli C.

Diabetes. 2001 Jul;50(7):1580-7.PMID: 11423479 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of polyamine depletion on caspase activation: a study with spermine synthase-deficient cells.

Stefanelli C, Pignatti C, Tantini B, Fattori M, Stanic I, Mackintosh CA, Flamigni F, Guarnieri C, Caldarera CM, Pegg AE.

Biochem J. 2001 Apr 1;355(Pt 1):199-206.PMID: 11256964 [PubMed - indexed for MEDLINE]Related articlesFree article

Purified protein derivative anergy in Kawasaki disease.

Kollmann TR, Klein EJ, Stefanelli CB, Marcuse EK.

Pediatr Infect Dis J. 2001 Jan;20(1):81-2.PMID: 11176575 [PubMed - indexed for MEDLINE]Related articles

Polyamines, NO and cGMP mediate stimulation of DNA synthesis by tumor necrosis factor and lipopolysaccharide in chick embryo cardiomyocytes.

Tantini B, Flamigni F, Pignatti C, Stefanelli C, Fattori M, Facchini A, Giordano E, Clô C, Caldarera CM.

Cardiovasc Res. 2001 Feb 1;49(2):408-16.PMID: 11164851 [PubMed - indexed for MEDLINE]Related articlesFree article

Signaling pathways leading to the induction of ornithine decarboxylase: opposite effects of p44/42 mitogen-activated protein kinase (MAPK) and p38 MAPK inhibitors.

Flamigni F, Facchini A, Giordano E, Tantini B, Stefanelli C.

Biochem Pharmacol. 2001 Jan 1;61(1):25-32.PMID: 11137705 [PubMed - indexed for MEDLINE]Related articles

Polyamines directly induce release of cytochrome c from heart mitochondria.

Stefanelli C, Stanic' I, Zini M, Bonavita F, Flamigni F, Zambonin L, Landi L, Pignatti C, Guarnieri C, Caldarera CM.

Biochem J. 2000 May 1;347 Pt 3:875-80.PMID: 10769194 [PubMed - indexed for MEDLINE]Related articlesFree article

The stability of porcine rotavirus in feces.

Ramos AP, Stefanelli CC, Linhares RE, de Brito BG, Santos N, Gouvea V, de Cassia Lima R, Nozawa C.

Vet Microbiol. 2000 Jan;71(1-2):1-8.PMID: 10665529 [PubMed - indexed for MEDLINE]Related articles

A case for routine screening of coronary artery origins during echocardiography: fortuitous discovery of a life-threatening coronary anomaly.

Stefanelli CB, Stevenson JG, Jones TK, Lester JR, Cecchin F.

J Am Soc Echocardiogr. 1999 Sep;12(9):769-72.PMID: 10477424 [PubMed - indexed for MEDLINE]Related articles

Nitric oxide can function as either a killer molecule or an antiapoptotic effector in cardiomyocytes.

Stefanelli C, Pignatti C, Tantini B, Stanic I, Bonavita F, Muscari C, Guarnieri C, Clo C, Caldarera CM.

Biochim Biophys Acta. 1999 Jul 8;1450(3):406-13.PMID: 10395951 [PubMed - indexed for MEDLINE]Related articles

p44/42 mitogen-activated protein kinase is involved in the expression of ornithine decarboxylase in leukaemia L1210 cells.

Flamigni F, Facchini A, Capanni C, Stefanelli C, Tantini B, Caldarera CM.

Biochem J. 1999 Jul 15;341 ( Pt 2):363-9.PMID: 10393094 [PubMed - indexed for MEDLINE]Related articlesFree article

Spermine triggers the activation of caspase-3 in a cell-free model of apoptosis.

Stefanelli C, Bonavita F, Stanic' I, Pignatti C, Flamigni F, Guarnieri C, Caldarera CM.

FEBS Lett. 1999 May 21;451(2):95-8.PMID: 10371145 [PubMed - indexed for MEDLINE]Related articles

Nitric oxide mediates either proliferation or cell death in cardiomyocytes. Involvement of polyamines.

Pignatti C, Tantini B, Stefanelli C, Giordano E, Bonavita F, Clô C, Caldarera CM.

Amino Acids. 1999;16(2):181-90.PMID: 10319188 [PubMed - indexed for MEDLINE]Related articles

Hepatic subcellular storage of beta-carotene in rats following diet supplementation.

Bianchi-Santamaria A, Stefanelli C, Cembran M, Gobbi M, Peschiera N, Vannini V, Santamaria L.

Int J Vitam Nutr Res. 1999 Jan;69(1):3-7.PMID: 10052014 [PubMed - indexed for MEDLINE]Related articles

Spermine causes caspase activation in leukaemia cells.

Stefanelli C, Bonavita F, Stanic' I, Mignani M, Facchini A, Pignatti C, Flamigni F, Caldarera CM.

FEBS Lett. 1998 Oct 23;437(3):233-6.PMID: 9824297 [PubMed - indexed for MEDLINE]Related articles

Modulation of the induction of ornithine decarboxylase by some opioid receptor agonists in immune cells and cardiomyocytes.

Pignatti C, Stanic I, Stefanelli C, Tantini B, Rossoni C, Flamigni F.

Mol Cell Biochem. 1998 Aug;185(1-2):47-53.PMID: 9746211 [PubMed - indexed for MEDLINE]Related articles

Inhibition of etoposide-induced apoptosis with peptide aldehyde inhibitors of proteasome.

Stefanelli C, Bonavita F, Stanic I, Pignatti C, Farruggia G, Masotti L, Guarnieri C, Caldarera CM.

Biochem J. 1998 Jun 15;332 ( Pt 3):661-5.PMID: 9620867 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of glucocorticoid-induced apoptosis with 5-aminoimidazole-4-carboxamide ribonucleoside, a cell-permeable activator of AMP-activated protein kinase.

Stefanelli C, Stanic I, Bonavita F, Flamigni F, Pignatti C, Guarnieri C, Caldarera CM.

Biochem Biophys Res Commun. 1998 Feb 24;243(3):821-6.PMID: 9500985 [PubMed - indexed for MEDLINE]Related articles

Phosphatidylinositol 3-kinase is required for the induction of ornithine decarboxylase in leukemia cells stimulated to growth.

Flamigni F, Marmiroli S, Capanni C, Stefanelli C, Guarnieri C, Caldarera CM.

Biochem Biophys Res Commun. 1997 Oct 29;239(3):729-33.PMID: 9367837 [PubMed - indexed for MEDLINE]Related articles

Inhibition of the expression of ornithine decarboxylase and c-Myc by cell-permeant ceramide in difluoromethylornithine-resistant leukaemia cells.

Flamigni F, Faenza I, Marmiroli S, Stanic' I, Giaccari A, Muscari C, Stefanelli C, Rossoni C.

Biochem J. 1997 Jun 15;324 ( Pt 3):783-9.PMID: 9210401 [PubMed - indexed for MEDLINE]Related articlesFree article

ATP depletion inhibits glucocorticoid-induced thymocyte apoptosis.

Stefanelli C, Bonavita F, Stanic' I, Farruggia G, Falcieri E, Robuffo I, Pignatti C, Muscari C, Rossoni C, Guarnieri C, Caldarera CM.

Biochem J. 1997 Mar 15;322 ( Pt 3):909-17.PMID: 9148768 [PubMed - indexed for MEDLINE]Related articlesFree article

Presence of a DNA-4236 bp deletion and 8-hydroxy-deoxyguanosine in mouse cardiac mitochondrial DNA during aging.

Muscari C, Giaccari A, Stefanelli C, Viticchi C, Giordano E, Guarnieri C, Caldarera CM.

Aging (Milano). 1996 Dec;8(6):429-33.PMID: 9061131 [PubMed - indexed for MEDLINE]Related articles

Inhibition of the expression of ornithine decarboxylase by haloperidol in difluoromethylornithine-resistant leukemia cells.

Flamigni F, Stanic I, Stefanelli C, Muscari C, Giaccari A, Rossoni C.

Biochem Pharmacol. 1996 Nov 8;52(9):1393-7. Erratum in: Biochem Pharmacol 1997 Feb 7;53(3):437. PMID: 8937449 [PubMed - indexed for MEDLINE]Related articles

Inhibition of the expression of ornithine decarboxylase by some kappa-opioidergic receptor ligands in difluoromethylornithine-resistant L1210 cells.

Flamigni F, Stefanelli C, Stanic I, Muscari C, Giaccari A, Rossoni C.

Biochim Biophys Acta. 1996 May 28;1311(3):204-10.PMID: 8664348 [PubMed - indexed for MEDLINE]Related articles

Oxygen tension influences DNA fragmentation and cell death in glucocorticoid-treated thymocytes.

Stefanelli C, Stanic I, Bonavita F, Muscari C, Pignatti C, Rossoni C, Caldarera CM.

Biochem Biophys Res Commun. 1995 Jul 17;212(2):300-6.PMID: 7626042 [PubMed - indexed for MEDLINE]Related articles