PubMed

Novel Obesity Risk Loci Do Not Determine Distribution of Body Fat Depots: A Whole-body MRI/MRS study.

Haupt A, Thamer C, Heni M, Machicao F, Machann J, Schick F, Stefan N, Fritsche A, Häring HU, Staiger H.

Obesity (Silver Spring). 2009 Nov 12. [Epub ahead of print]PMID: 19910938 [PubMed - as supplied by publisher]Related articles

Circulating Palmitoleate strongly and independently predicts Insulin Sensitivity in Humans.

Stefan N, Kantartzis K, Celebi N, Staiger H, Machann J, Schick F, Cegan A, Elcnerova M, Schleicher E, Fritsche A, Häring HU.

Diabetes Care. 2009 Nov 4. [Epub ahead of print]PMID: 19889804 [PubMed - as supplied by publisher]Related articles

Hepatic Lipid Composition and Stearoyl-Coenzyme A Desaturase 1 mRNA Expression Can Be Estimated from Plasma VLDL Fatty Acid Ratios.

Peter A, Cegan A, Wagner S, Lehmann R, Stefan N, Königsrainer A, Königsrainer I, Häring HU, Schleicher E.

Clin Chem. 2009 Oct 22. [Epub ahead of print]PMID: 19850634 [PubMed - as supplied by publisher]Related articles

The insulin effect on cerebrocortical theta activity is associated with serum concentrations of saturated nonesterified Fatty acids.

Tschritter O, Preissl H, Hennige AM, Sartorius T, Grichisch Y, Stefan N, Guthoff M, Düsing S, Machann J, Schleicher E, Cegan A, Birbaumer N, Fritsche A, Häring HU.

J Clin Endocrinol Metab. 2009 Nov;94(11):4600-7. Epub 2009 Oct 9.PMID: 19820026 [PubMed - in process]Related articles

Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study.

Boesgaard TW, Gjesing AP, Grarup N, Rutanen J, Jansson PA, Hribal ML, Sesti G, Fritsche A, Stefan N, Staiger H, Häring H, Smith U, Laakso M, Pedersen O, Hansen T; EUGENE2 Consortium.

PLoS One. 2009 Sep 30;4(9):e7236.PMID: 19789630 [PubMed - in process]Related articlesFree article

High baseline vitamin C levels do not prevent a positive outcome of a lifestyle intervention.

Thamer C, Machicao F, Stefan N, Fritsche A, Häring HU.

Diabetes Care. 2009 Sep;32(9):e112. No abstract available. PMID: 19717817 [PubMed - indexed for MEDLINE]Related articles

Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus.

Müssig K, Staiger H, Machicao F, Machann J, Schick F, Schäfer SA, Claussen CD, Holst JJ, Gallwitz B, Stefan N, Fritsche A, Häring HU.

Metabolism. 2009 Dec;58(12):1809-11. Epub 2009 Aug 28.PMID: 19716570 [PubMed - in process]Related articles

Common polymorphisms within the NR4A3 locus, encoding the orphan nuclear receptor Nor-1, are associated with enhanced beta-cell function in non-diabetic subjects.

Weyrich P, Staiger H, Stancáková A, Schäfer SA, Kirchhoff K, Ullrich S, Ranta F, Gallwitz B, Stefan N, Machicao F, Kuusisto J, Laakso M, Fritsche A, Häring HU.

BMC Med Genet. 2009 Aug 14;10:77.PMID: 19682370 [PubMed - indexed for MEDLINE]Related articlesFree article

Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene.

Kantartzis K, Peter A, Machicao F, Machann J, Wagner S, Königsrainer I, Königsrainer A, Schick F, Fritsche A, Häring HU, Stefan N.

Diabetes. 2009 Nov;58(11):2616-23. Epub 2009 Aug 3.PMID: 19651814 [PubMed - in process]Related articles

The importance of brown adipose tissue.

Stefan N, Pfannenberg C, Häring HU.

N Engl J Med. 2009 Jul 23;361(4):416-7; author reply 418-21. No abstract available. PMID: 19630141 [PubMed - indexed for MEDLINE]Related articles

[Individualized prevention of type 2 diabetes]

Stefan N, Fritsche A, Häring HU.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2009 Jul;52(7):677-82. German. PMID: 19626284 [PubMed - indexed for MEDLINE]Related articles

High plasma fetuin-A is associated with increased carotid intima-media thickness in a middle-aged population.

Rittig K, Thamer C, Haupt A, Machann J, Peter A, Balletshofer B, Fritsche A, Haring HU, Stefan N.

Atherosclerosis. 2009 May 22. [Epub ahead of print] No abstract available. PMID: 19615685 [PubMed - as supplied by publisher]Related articles

Non-invasive assessment and quantification of liver steatosis by ultrasound, computed tomography and magnetic resonance.

Schwenzer NF, Springer F, Schraml C, Stefan N, Machann J, Schick F.

J Hepatol. 2009 Sep;51(3):433-45. Epub 2009 Jun 11.PMID: 19604596 [PubMed - in process]Related articles

mRNA concentrations of MIF in subcutaneous abdominal adipose cells are associated with adipocyte size and insulin action.

Koska J, Stefan N, Dubois S, Trinidad C, Considine RV, Funahashi T, Bunt JC, Ravussin E, Permana PA.

Int J Obes (Lond). 2009 Aug;33(8):842-50. Epub 2009 Jun 9.PMID: 19506561 [PubMed - in process]Related articles

Individual stearoyl-coa desaturase 1 expression modulates endoplasmic reticulum stress and inflammation in human myotubes and is associated with skeletal muscle lipid storage and insulin sensitivity in vivo.

Peter A, Weigert C, Staiger H, Machicao F, Schick F, Machann J, Stefan N, Thamer C, Häring HU, Schleicher E.

Diabetes. 2009 Aug;58(8):1757-65. Epub 2009 May 28.PMID: 19478146 [PubMed - indexed for MEDLINE]Related articlesFree article

Intermuscular adipose tissue (IMAT): association with other adipose tissue compartments and insulin sensitivity.

Boettcher M, Machann J, Stefan N, Thamer C, Häring HU, Claussen CD, Fritsche A, Schick F.

J Magn Reson Imaging. 2009 Jun;29(6):1340-5.PMID: 19422021 [PubMed - indexed for MEDLINE]Related articles

Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion.

Müssig K, Staiger H, Machicao F, Kirchhoff K, Guthoff M, Schäfer SA, Kantartzis K, Silbernagel G, Stefan N, Holst JJ, Gallwitz B, Häring HU, Fritsche A.

Diabetes. 2009 Jul;58(7):1715-20. Epub 2009 Apr 14.PMID: 19366866 [PubMed - indexed for MEDLINE]Related articlesFree article

AHSG gene variation is not associated with regional body fat distribution--a magnetic resonance study.

Müssig K, Staiger H, Machicao F, Machann J, Hennige AM, Schick F, Claussen CD, Fritsche A, Häring HU, Stefan N.

Exp Clin Endocrinol Diabetes. 2009 Sep;117(8):432-7. Epub 2009 Apr 8.PMID: 19358088 [PubMed - in process]Related articles

A common genetic variant in WFS1 determines impaired glucagon-like peptide-1-induced insulin secretion.

Schäfer SA, Müssig K, Staiger H, Machicao F, Stefan N, Gallwitz B, Häring HU, Fritsche A.

Diabetologia. 2009 Jun;52(6):1075-82. Epub 2009 Mar 28.PMID: 19330314 [PubMed - indexed for MEDLINE]Related articles

RARRES2, encoding the novel adipokine chemerin, is a genetic determinant of disproportionate regional body fat distribution: a comparative magnetic resonance imaging study.

Müssig K, Staiger H, Machicao F, Thamer C, Machann J, Schick F, Claussen CD, Stefan N, Fritsche A, Häring HU.

Metabolism. 2009 Apr;58(4):519-24.PMID: 19303973 [PubMed - indexed for MEDLINE]Related articles

The inhibitory effect of recent type 2 diabetes risk loci on insulin secretion is modulated by insulin sensitivity.

Haupt A, Guthoff M, Schäfer SA, Kirchhoff K, Machicao F, Gallwitz B, Staiger H, Stefan N, Fritsche A, Häring HU.

J Clin Endocrinol Metab. 2009 May;94(5):1775-80. Epub 2009 Mar 3.PMID: 19258404 [PubMed - indexed for MEDLINE]Related articles

The risk allele load accelerates the age-dependent decline in beta cell function.

Haupt A, Staiger H, Schäfer SA, Kirchhoff K, Guthoff M, Machicao F, Gallwitz B, Stefan N, Häring HU, Fritsche A.

Diabetologia. 2009 Mar;52(3):457-62. Epub 2009 Jan 27.PMID: 19172244 [PubMed - indexed for MEDLINE]Related articles

Adiponectin oligomers and ectopic fat in liver and skeletal muscle in humans.

Kantartzis K, Staiger H, Machann J, Schick F, Claussen CD, Machicao F, Fritsche A, Häring HU, Stefan N.

Obesity (Silver Spring). 2009 Feb;17(2):390-2. Epub 2008 Oct 30.PMID: 19169222 [PubMed - indexed for MEDLINE]Related articles

Psychological effects of prevention: do participants of a type 2 diabetes prevention program experience increased mental distress?

Giel KE, Enck P, Zipfel S, Schrauth M, Bury A, Graf M, Kümmerle S, Guthoff M, Stefan N, Häring HU, Fritsche A.

Diabetes Metab Res Rev. 2009 Jan;25(1):83-8.PMID: 19145589 [PubMed - indexed for MEDLINE]Related articles

Association of common genetic variation in the FOXO1 gene with beta-cell dysfunction, impaired glucose tolerance, and type 2 diabetes.

Müssig K, Staiger H, Machicao F, Stancáková A, Kuusisto J, Laakso M, Thamer C, Machann J, Schick F, Claussen CD, Stefan N, Fritsche A, Häring HU.

J Clin Endocrinol Metab. 2009 Apr;94(4):1353-60. Epub 2009 Jan 13.PMID: 19141580 [PubMed - indexed for MEDLINE]Related articles

Polymorphisms within the novel type 2 diabetes risk locus MTNR1B determine beta-cell function.

Staiger H, Machicao F, Schäfer SA, Kirchhoff K, Kantartzis K, Guthoff M, Silbernagel G, Stefan N, Häring HU, Fritsche A.

PLoS One. 2008;3(12):e3962. Epub 2008 Dec 17.PMID: 19088850 [PubMed - indexed for MEDLINE]Related articlesFree article

Muscle-derived angiopoietin-like protein 4 is induced by fatty acids via peroxisome proliferator-activated receptor (PPAR)-delta and is of metabolic relevance in humans.

Staiger H, Haas C, Machann J, Werner R, Weisser M, Schick F, Machicao F, Stefan N, Fritsche A, Häring HU.

Diabetes. 2009 Mar;58(3):579-89. Epub 2008 Dec 15.PMID: 19074989 [PubMed - indexed for MEDLINE]Related articlesFree article

High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in non-alcoholic fatty liver disease.

Kantartzis K, Thamer C, Peter A, Machann J, Schick F, Schraml C, Königsrainer A, Königsrainer I, Kröber S, Niess A, Fritsche A, Häring HU, Stefan N.

Gut. 2009 Sep;58(9):1281-8. Epub 2008 Dec 11.PMID: 19074179 [PubMed - indexed for MEDLINE]Related articles

Animal Trichinella infection in Romania: geographical heterogeneity for the last 8 years.

Blaga R, Durand B, Stoichici A, Gherman C, Stefan N, Cozma V, Boireau P.

Vet Parasitol. 2009 Feb 23;159(3-4):290-4. Epub 2008 Oct 22.PMID: 19062190 [PubMed - in process]Related articles

Selective association of plasma non-esterified fatty acid species with circulating interleukin-8 concentrations in humans.

Staiger H, Wöll J, Haas C, Machicao F, Schleicher ED, Fritsche A, Stefan N, Häring HU.

Exp Clin Endocrinol Diabetes. 2009 Jan;117(1):21-7. Epub 2008 Dec 3.PMID: 19053024 [PubMed - indexed for MEDLINE]Related articles

Variation in the FTO gene influences food intake but not energy expenditure.

Haupt A, Thamer C, Staiger H, Tschritter O, Kirchhoff K, Machicao F, Häring HU, Stefan N, Fritsche A.

Exp Clin Endocrinol Diabetes. 2009 Apr;117(4):194-7. Epub 2008 Dec 3.PMID: 19053021 [PubMed - indexed for MEDLINE]Related articles

Plasma fetuin-a levels and the risk of myocardial infarction and ischemic stroke.

Weikert C, Stefan N, Schulze MB, Pischon T, Berger K, Joost HG, Häring HU, Boeing H, Fritsche A.

Circulation. 2008 Dec 9;118(24):2555-62. Epub 2008 Nov 24.PMID: 19029462 [PubMed - indexed for MEDLINE]Related articles

Association of fetuin-A level and diabetes risk.

Stefan N, Häring HU, Schulze MB.

JAMA. 2008 Nov 19;300(19):2247; author reply 2247-8. No abstract available. PMID: 19017904 [PubMed - indexed for MEDLINE]Related articles

SIRT1 genetic variants associate with the metabolic response of Caucasians to a controlled lifestyle intervention--the TULIP Study.

Weyrich P, Machicao F, Reinhardt J, Machann J, Schick F, Tschritter O, Stefan N, Fritsche A, Häring HU.

BMC Med Genet. 2008 Nov 12;9:100.PMID: 19014491 [PubMed - indexed for MEDLINE]Related articlesFree article

T2* relaxometry in liver, pancreas, and spleen in a healthy cohort of one hundred twenty-nine subjects-correlation with age, gender, and serum ferritin.

Schwenzer NF, Machann J, Haap MM, Martirosian P, Schraml C, Liebig G, Stefan N, Häring HU, Claussen CD, Fritsche A, Schick F.

Invest Radiol. 2008 Dec;43(12):854-60.PMID: 19002057 [PubMed - indexed for MEDLINE]Related articles

Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies.

Friedrich B, Weyrich P, Stancáková A, Wang J, Kuusisto J, Laakso M, Sesti G, Succurro E, Smith U, Hansen T, Pedersen O, Machicao F, Schäfer S, Lang F, Risler T, Ullrich S, Stefan N, Fritsche A, Häring HU.

PLoS One. 2008;3(11):e3506. Epub 2008 Nov 5.PMID: 18985156 [PubMed - indexed for MEDLINE]Related articlesFree article

The DGAT2 gene is a candidate for the dissociation between fatty liver and insulin resistance in humans.

Kantartzis K, Machicao F, Machann J, Schick F, Fritsche A, Häring HU, Stefan N.

Clin Sci (Lond). 2009 Mar;116(6):531-7.PMID: 18980578 [PubMed - indexed for MEDLINE]Related articles

Association of the FTO rs9939609 single nucleotide polymorphism with C-reactive protein levels.

Fisher E, Schulze MB, Stefan N, Häring HU, Döring F, Joost HG, Al-Hasani H, Boeing H, Pischon T.

Obesity (Silver Spring). 2009 Feb;17(2):330-4. Epub 2008 Oct 23.PMID: 18948966 [PubMed - indexed for MEDLINE]Related articles

The L162V polymorphism of the peroxisome proliferator activated receptor alpha gene (PPARA) is not associated with type 2 diabetes, BMI or body fat composition.

Silbernagel G, Stefan N, Hoffmann MM, Machicao-Arano F, Machann J, Schick F, Winkelmann BR, Boehm BO, Häring HU, Fritsche A, März W.

Exp Clin Endocrinol Diabetes. 2009 Mar;117(3):113-8. Epub 2008 Aug 25.PMID: 18726867 [PubMed - indexed for MEDLINE]Related articles

Genetic variability of procolipase associates with altered insulin secretion in non-diabetic Caucasians.

Weyrich P, Albet S, Lammers R, Machicao F, Fritsche A, Stefan N, Häring HU.

Exp Clin Endocrinol Diabetes. 2009 Feb;117(2):83-7. Epub 2008 Aug 25.PMID: 18726866 [PubMed - indexed for MEDLINE]Related articles

Causes and metabolic consequences of Fatty liver.

Stefan N, Kantartzis K, Häring HU.

Endocr Rev. 2008 Dec;29(7):939-60. Epub 2008 Aug 21. Review.PMID: 18723451 [PubMed - indexed for MEDLINE]Related articles

Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes.

Staiger H, Machicao F, Kantartzis K, Schäfer SA, Kirchhoff K, Guthoff M, Silbernagel G, Stefan N, Fritsche A, Häring HU.

PLoS One. 2008 Aug 20;3(8):e3019.PMID: 18714373 [PubMed - indexed for MEDLINE]Related articlesFree article

Perivascular fatty tissue at the brachial artery is linked to insulin resistance but not to local endothelial dysfunction.

Rittig K, Staib K, Machann J, Böttcher M, Peter A, Schick F, Claussen C, Stefan N, Fritsche A, Häring HU, Balletshofer B.

Diabetologia. 2008 Nov;51(11):2093-9. Epub 2008 Aug 20.PMID: 18712517 [PubMed - indexed for MEDLINE]Related articles

Identification and characterization of metabolically benign obesity in humans.

Stefan N, Kantartzis K, Machann J, Schick F, Thamer C, Rittig K, Balletshofer B, Machicao F, Fritsche A, Häring HU.

Arch Intern Med. 2008 Aug 11;168(15):1609-16.PMID: 18695074 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma fetuin-A levels and the risk of type 2 diabetes.

Stefan N, Fritsche A, Weikert C, Boeing H, Joost HG, Häring HU, Schulze MB.

Diabetes. 2008 Oct;57(10):2762-7. Epub 2008 Jul 15.PMID: 18633113 [PubMed - indexed for MEDLINE]Related articlesFree article

Distribution of subcutaneous fat predicts insulin action in obesity in sex-specific manner.

Koska J, Stefan N, Votruba SB, Smith SR, Krakoff J, Bunt JC.

Obesity (Silver Spring). 2008 Sep;16(9):2003-9.PMID: 18551127 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of variation in the FTO gene on whole body fat distribution, ectopic fat, and weight loss.

Haupt A, Thamer C, Machann J, Kirchhoff K, Stefan N, Tschritter O, Machicao F, Schick F, Häring HU, Fritsche A.

Obesity (Silver Spring). 2008 Aug;16(8):1969-72. Epub 2008 May 29.PMID: 18535549 [PubMed - indexed for MEDLINE]Related articles

Genetic variation within the ANGPTL4 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus.

Staiger H, Machicao F, Werner R, Guirguis A, Weisser M, Stefan N, Fritsche A, Häring HU.

Metabolism. 2008 May;57(5):637-43.PMID: 18442626 [PubMed - indexed for MEDLINE]Related articles

Quantification of pancreatic lipomatosis and liver steatosis by MRI: comparison of in/opposed-phase and spectral-spatial excitation techniques.

Schwenzer NF, Machann J, Martirosian P, Stefan N, Schraml C, Fritsche A, Claussen CD, Schick F.

Invest Radiol. 2008 May;43(5):330-7.PMID: 18424954 [PubMed - indexed for MEDLINE]Related articles

(1)H MR spectroscopy of skeletal muscle, liver and bone marrow.

Machann J, Stefan N, Schick F.

Eur J Radiol. 2008 Aug;67(2):275-84. Epub 2008 Apr 10. Review.PMID: 18406092 [PubMed - indexed for MEDLINE]Related articles