PubMed

Recombinant human relaxin in the treatment of systemic sclerosis with diffuse cutaneous involvement: a randomized, double-blind, placebo-controlled trial.

Khanna D, Clements PJ, Furst DE, Korn JH, Ellman M, Rothfield N, Wigley FM, Moreland LW, Silver R, Kim YH, Steen VD, Firestein GS, Kavanaugh AF, Weisman M, Mayes MD, Collier D, Csuka ME, Simms R, Merkel PA, Medsger TA Jr, Sanders ME, Maranian P, Seibold JR; Relaxin Investigators and the Scleroderma Clinical Trials Consortium.

Arthritis Rheum. 2009 Apr;60(4):1102-11.PMID: 19333948 [PubMed - indexed for MEDLINE]Related articles

Lower extremity ulcers in connective tissue disease.

Shanmugam VK, Steen VD, Cupps TR.

Isr Med Assoc J. 2008 Jul;10(7):534-6. Review.PMID: 18751636 [PubMed - indexed for MEDLINE]Related articlesFree article

The many faces of scleroderma.

Steen VD.

Rheum Dis Clin North Am. 2008 Feb;34(1):1-15; v. Review.PMID: 18329529 [PubMed - indexed for MEDLINE]Related articles

Pulmonary arterial hypertension and severe pulmonary fibrosis in systemic sclerosis patients with a nucleolar antibody.

Steen VD, Lucas M, Fertig N, Medsger TA Jr.

J Rheumatol. 2007 Nov;34(11):2230-5. Epub 2007 Oct 15.PMID: 17937469 [PubMed - indexed for MEDLINE]Related articles

Development of a provisional core set of response measures for clinical trials of systemic sclerosis.

Khanna D, Lovell DJ, Giannini E, Clements PJ, Merkel PA, Seibold JR, Matucci-Cerinic M, Denton CP, Mayes MD, Steen VD, Varga J, Furst DE; Scleroderma Clinical Trials Consortium co-authors.

Ann Rheum Dis. 2008 May;67(5):703-9. Epub 2007 Sep 24.PMID: 17893248 [PubMed - indexed for MEDLINE]Related articles

Clinical trials in systemic sclerosis: lessons learned and outcomes.

Matucci-Cerinic M, Steen VD, Furst DE, Seibold JR.

Arthritis Res Ther. 2007;9 Suppl 2:S7. Review.PMID: 17767745 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical subsets, skin thickness progression rate, and serum antibody levels in systemic sclerosis patients with anti-topoisomerase I antibody.

Perera A, Fertig N, Lucas M, Rodriguez-Reyna TS, Hu P, Steen VD, Medsger TA Jr.

Arthritis Rheum. 2007 Aug;56(8):2740-6.PMID: 17665460 [PubMed - indexed for MEDLINE]Related articlesFree article

Pregnancy in scleroderma.

Steen VD.

Rheum Dis Clin North Am. 2007 May;33(2):345-58, vii. Review.PMID: 17499711 [PubMed - indexed for MEDLINE]Related articles

Changes in causes of death in systemic sclerosis, 1972-2002.

Steen VD, Medsger TA.

Ann Rheum Dis. 2007 Jul;66(7):940-4. Epub 2007 Feb 28.PMID: 17329309 [PubMed - indexed for MEDLINE]Related articles

Lung transplantation in scleroderma compared with idiopathic pulmonary fibrosis and idiopathic pulmonary arterial hypertension.

Schachna L, Medsger TA Jr, Dauber JH, Wigley FM, Braunstein NA, White B, Steen VD, Conte JV, Yang SC, McCurry KR, Borja MC, Plaskon DE, Orens JB, Gelber AC.

Arthritis Rheum. 2006 Dec;54(12):3954-61.PMID: 17133609 [PubMed - indexed for MEDLINE]Related articlesFree article

Childhood onset systemic sclerosis: classification, clinical and serologic features, and survival in comparison with adult onset disease.

Scalapino K, Arkachaisri T, Lucas M, Fertig N, Helfrich DJ, Londino AV Jr, Steen VD, Medsger TA Jr.

J Rheumatol. 2006 May;33(5):1004-13. Epub 2006 Apr 1.PMID: 16583463 [PubMed - indexed for MEDLINE]Related articles

Minimally important difference in diffuse systemic sclerosis: results from the D-penicillamine study.

Khanna D, Furst DE, Hays RD, Park GS, Wong WK, Seibold JR, Mayes MD, White B, Wigley FF, Weisman M, Barr W, Moreland L, Medsger TA Jr, Steen VD, Martin RW, Collier D, Weinstein A, Lally EV, Varga J, Weiner SR, Andrews B, Abeles M, Clements PJ.

Ann Rheum Dis. 2006 Oct;65(10):1325-9. Epub 2006 Mar 15.PMID: 16540546 [PubMed - indexed for MEDLINE]Related articlesFree article

The lung in systemic sclerosis.

Steen VD.

J Clin Rheumatol. 2005 Feb;11(1):40-6. Review. No abstract available. PMID: 16357695 [PubMed - indexed for MEDLINE]Related articles

Autoantibodies in systemic sclerosis.

Steen VD.

Semin Arthritis Rheum. 2005 Aug;35(1):35-42.PMID: 16084222 [PubMed - indexed for MEDLINE]Related articles

Responsiveness of the SF-36 and the Health Assessment Questionnaire Disability Index in a systemic sclerosis clinical trial.

Khanna D, Furst DE, Clements PJ, Park GS, Hays RD, Yoon J, Korn JH, Merkel PA, Rothfield N, Wigley FM, Moreland LW, Silver R, Steen VD, Weisman M, Mayes MD, Collier DH, Medsger TA Jr, Seibold JR; Relaxin Study Group; Scleroderma Clinical Trials Consortium.

J Rheumatol. 2005 May;32(5):832-40.PMID: 15868618 [PubMed - indexed for MEDLINE]Related articles

Kidney disease other than renal crisis in patients with diffuse scleroderma.

Steen VD, Syzd A, Johnson JP, Greenberg A, Medsger TA Jr.

J Rheumatol. 2005 Apr;32(4):649-55.PMID: 15801020 [PubMed - indexed for MEDLINE]Related articles

Correlation of the degree of dyspnea with health-related quality of life, functional abilities, and diffusing capacity for carbon monoxide in patients with systemic sclerosis and active alveolitis: results from the Scleroderma Lung Study.

Khanna D, Clements PJ, Furst DE, Chon Y, Elashoff R, Roth MD, Sterz MG, Chung J, FitzGerald JD, Seibold JR, Varga J, Theodore A, Wigley FM, Silver RM, Steen VD, Mayes MD, Connolly MK, Fessler BJ, Rothfield NF, Mubarak K, Molitor J, Tashkin DP; Scleroderma Lung Study Group.

Arthritis Rheum. 2005 Feb;52(2):592-600.PMID: 15692967 [PubMed - indexed for MEDLINE]Related articlesFree article

Assessment of kidney involvement.

Steen VD, Mayes MD, Merkel PA.

Clin Exp Rheumatol. 2003;21(3 Suppl 29):S29-31. Review.PMID: 12889219 [PubMed - indexed for MEDLINE]Related articles

Scleroderma renal crisis.

Steen VD.

Rheum Dis Clin North Am. 2003 May;29(2):315-33. Review.PMID: 12841297 [PubMed - indexed for MEDLINE]Related articles

A comparison between anti-Th/To- and anticentromere antibody-positive systemic sclerosis patients with limited cutaneous involvement.

Mitri GM, Lucas M, Fertig N, Steen VD, Medsger TA Jr.

Arthritis Rheum. 2003 Jan;48(1):203-9.PMID: 12528120 [PubMed - indexed for MEDLINE]Related articlesFree article

Improvement in skin thickening in systemic sclerosis associated with improved survival.

Steen VD, Medsger TA Jr.

Arthritis Rheum. 2001 Dec;44(12):2828-35.PMID: 11762943 [PubMed - indexed for MEDLINE]Related articles

Treatment of systemic sclerosis.

Steen VD.

Am J Clin Dermatol. 2001;2(5):315-25. Review.PMID: 11721650 [PubMed - indexed for MEDLINE]Related articles

Skin thickness score as a predictor and correlate of outcome in systemic sclerosis: high-dose versus low-dose penicillamine trial.

Clements PJ, Hurwitz EL, Wong WK, Seibold JR, Mayes M, White B, Wigley F, Weisman M, Barr W, Moreland L, Medsger TA Jr, Steen VD, Martin RW, Collier D, Weinstein A, Lally E, Varga J, Weiner SR, Andrews B, Abeles M, Furst DE.

Arthritis Rheum. 2000 Nov;43(11):2445-54.PMID: 11083267 [PubMed - indexed for MEDLINE]Related articlesFree article

Severe organ involvement in systemic sclerosis with diffuse scleroderma.

Steen VD, Medsger TA Jr.

Arthritis Rheum. 2000 Nov;43(11):2437-44.PMID: 11083266 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term outcomes of scleroderma renal crisis.

Steen VD, Medsger TA Jr.

Ann Intern Med. 2000 Oct 17;133(8):600-3.PMID: 11033587 [PubMed - indexed for MEDLINE]Related articlesFree article

Occupational scleroderma.

Steen VD.

Curr Opin Rheumatol. 1999 Nov;11(6):490-4. Review.PMID: 10551673 [PubMed - indexed for MEDLINE]Related articles

A disease severity scale for systemic sclerosis: development and testing.

Medsger TA Jr, Silman AJ, Steen VD, Black CM, Akesson A, Bacon PA, Harris CA, Jablonska S, Jayson MI, Jimenez SA, Krieg T, Leroy EC, Maddison PJ, Russell ML, Schachter RK, Wollheim FA, Zacharaie H.

J Rheumatol. 1999 Oct;26(10):2159-67.PMID: 10529133 [PubMed - indexed for MEDLINE]Related articles

Pregnancy in women with systemic sclerosis.

Steen VD.

Obstet Gynecol. 1999 Jul;94(1):15-20.PMID: 10389711 [PubMed - indexed for MEDLINE]Related articles

Early undifferentiated connective tissue disease (CTD). VI. An inception cohort after 10 years: disease remissions and changes in diagnoses in well established and undifferentiated CTD.

Williams HJ, Alarcon GS, Joks R, Steen VD, Bulpitt K, Clegg DO, Ziminski CM, Luggen ME, St Clair EW, Willkens RF, Yarboro C, Morgan JG, Egger MJ, Ward JR.

J Rheumatol. 1999 Apr;26(4):816-25.PMID: 10229402 [PubMed - indexed for MEDLINE]Related articles

Fertility and pregnancy outcome in women with systemic sclerosis.

Steen VD, Medsger TA Jr.

Arthritis Rheum. 1999 Apr;42(4):763-8.PMID: 10211892 [PubMed - indexed for MEDLINE]Related articlesFree article

Pregnancy in systemic sclerosis.

Steen VD.

Scand J Rheumatol Suppl. 1998;107:72-5. Review. No abstract available. PMID: 9759138 [PubMed - indexed for MEDLINE]Related articles

Case-control study of corticosteroids and other drugs that either precipitate or protect from the development of scleroderma renal crisis.

Steen VD, Medsger TA Jr.

Arthritis Rheum. 1998 Sep;41(9):1613-9.PMID: 9751093 [PubMed - indexed for MEDLINE]Related articlesFree article

Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States.

Lawrence RC, Helmick CG, Arnett FC, Deyo RA, Felson DT, Giannini EH, Heyse SP, Hirsch R, Hochberg MC, Hunder GG, Liang MH, Pillemer SR, Steen VD, Wolfe F.

Arthritis Rheum. 1998 May;41(5):778-99.PMID: 9588729 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical manifestations of systemic sclerosis.

Steen VD.

Semin Cutan Med Surg. 1998 Mar;17(1):48-54. Review.PMID: 9512107 [PubMed - indexed for MEDLINE]Related articles

Early undifferentiated connective tissue disease. V. An inception cohort 5 years later: disease remissions and changes in diagnoses in well established and undifferentiated connective tissue diseases.

Williams HJ, Alarcón GS, Neuner R, Steen VD, Bulpitt K, Clegg DO, Ziminski CM, Luggen ME, Polisson RP, Willkens RF, Yarboro C, Morgan J, Egger MJ, Ward JR.

J Rheumatol. 1998 Feb;25(2):261-8.PMID: 9489817 [PubMed - indexed for MEDLINE]Related articles

The modified Rodnan skin score is an accurate reflection of skin biopsy thickness in systemic sclerosis.

Furst DE, Clements PJ, Steen VD, Medsger TA Jr, Masi AT, D'Angelo WA, Lachenbruch PA, Grau RG, Seibold JR.

J Rheumatol. 1998 Jan;25(1):84-8.PMID: 9458208 [PubMed - indexed for MEDLINE]Related articles

The value of the Health Assessment Questionnaire and special patient-generated scales to demonstrate change in systemic sclerosis patients over time.

Steen VD, Medsger TA Jr.

Arthritis Rheum. 1997 Nov;40(11):1984-91.PMID: 9365087 [PubMed - indexed for MEDLINE]Related articles

The palpable tendon friction rub: an important physical examination finding in patients with systemic sclerosis.

Steen VD, Medsger TA Jr.

Arthritis Rheum. 1997 Jun;40(6):1146-51.PMID: 9182926 [PubMed - indexed for MEDLINE]Related articles

Incidence of systemic sclerosis in Allegheny County, Pennsylvania. A twenty-year study of hospital-diagnosed cases, 1963-1982.

Steen VD, Oddis CV, Conte CG, Janoski J, Casterline GZ, Medsger TA Jr.

Arthritis Rheum. 1997 Mar;40(3):441-5.PMID: 9082931 [PubMed - indexed for MEDLINE]Related articles

Scleroderma and pregnancy.

Steen VD.

Rheum Dis Clin North Am. 1997 Feb;23(1):133-47. Review.PMID: 9031379 [PubMed - indexed for MEDLINE]Related articles

Scleroderma renal crisis.

Steen VD.

Rheum Dis Clin North Am. 1996 Nov;22(4):861-78. Review.PMID: 8923600 [PubMed - indexed for MEDLINE]Related articles

Autoantibodies in systemic sclerosis.

Steen VD.

Bull Rheum Dis. 1996 Oct;45(6):6-8. No abstract available. PMID: 8885479 [PubMed - indexed for MEDLINE]Related articles

Compression of the median nerve proximal to the carpal tunnel in scleroderma.

Ko CY, Jones NF, Steen VD.

J Hand Surg Am. 1996 May;21(3):363-5. No abstract available. PMID: 8724461 [PubMed - indexed for MEDLINE]Related articles

Soluble serum interleukin 2 receptors in patients with systemic sclerosis.

Steen VD, Engel EE, Charley MR, Medsger TA Jr.

J Rheumatol. 1996 Apr;23(4):646-9.PMID: 8730120 [PubMed - indexed for MEDLINE]Related articles

Isolated pulmonary hypertension in systemic sclerosis with diffuse cutaneous involvement: association with serum anti-U3RNP antibody.

Sacks DG, Okano Y, Steen VD, Curtiss E, Shapiro LS, Medsger TA Jr.

J Rheumatol. 1996 Apr;23(4):639-42.PMID: 8730118 [PubMed - indexed for MEDLINE]Related articles

Thallium perfusion defects predict subsequent cardiac dysfunction in patients with systemic sclerosis.

Steen VD, Follansbee WP, Conte CG, Medsger TA Jr.

Arthritis Rheum. 1996 Apr;39(4):677-81.PMID: 8630120 [PubMed - indexed for MEDLINE]Related articles

Early undifferentiated connective tissue disease. IV.Musculoskeletal manifestations in a large cohort of patients with undifferentiated connective tissue diseases compared with cohorts of patients with well-established connective tissue diseases: followup analyses in patients with unexplained polyarthritis and patients with rheumatoid arthritis at baseline.

Alarcón GS, Willkens RF, Ward JR, Clegg DO, Morgan JG, Ma KN, Singer JZ, Steen VD, Paulus HE, Luggen ME, Polisson RP, Ziminski CM, Yarboro C, Williams HJ.

Arthritis Rheum. 1996 Mar;39(3):403-14.PMID: 8607889 [PubMed - indexed for MEDLINE]Related articles

Therapy for severe interstitial lung disease in systemic sclerosis. A retrospective study.

Steen VD, Lanz JK Jr, Conte C, Owens GR, Medsger TA Jr.

Arthritis Rheum. 1994 Sep;37(9):1290-6.PMID: 7945491 [PubMed - indexed for MEDLINE]Related articles

Severe restrictive lung disease in systemic sclerosis.

Steen VD, Conte C, Owens GR, Medsger TA Jr.

Arthritis Rheum. 1994 Sep;37(9):1283-9.PMID: 7945490 [PubMed - indexed for MEDLINE]Related articles

Comparison of hydroxychloroquine and placebo in the treatment of the arthropathy of mild systemic lupus erythematosus.

Williams HJ, Egger MJ, Singer JZ, Willkens RF, Kalunian KC, Clegg DO, Skosey JL, Brooks RH, Alarcón GS, Steen VD, et al.

J Rheumatol. 1994 Aug;21(8):1457-62.PMID: 7983646 [PubMed - indexed for MEDLINE]Related articles