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The Role of Insulin-Like Growth Factor (IGF) Binding Protein-2 in the Insulin-Mediated Decrease in IGF-I Bioactivity.

Arafat AM, Weickert MO, Frystyk J, Spranger J, Schöfl C, Möhlig M, Pfeiffer AF.

J Clin Endocrinol Metab. 2009 Oct 21. [Epub ahead of print]PMID: 19846739 [PubMed - as supplied by publisher]Related articles

Polymorphisms within insulin-degrading enzyme (IDE) gene determine insulin metabolism and risk of type 2 diabetes.

Rudovich N, Pivovarova O, Fisher E, Fischer-Rosinsky A, Spranger J, Möhlig M, Schulze MB, Boeing H, Pfeiffer AF.

J Mol Med. 2009 Oct 7. [Epub ahead of print]PMID: 19809796 [PubMed - as supplied by publisher]Related articles

HbA1c is associated with intima media thickness in individuals with normal glucose tolerance.

Bobbert T, Mai K, Fischer-Rosinsky A, Pfeiffer AF, Spranger J.

Diabetes Care. 2009 Oct 6. [Epub ahead of print]PMID: 19808917 [PubMed - as supplied by publisher]Related articles

Acute hyperinsulinaemia and hyperlipidaemia modify circulating adiponectin and its oligomers.

Bobbert T, Weicht J, Mai K, Möhlig M, Pfeiffer AF, Spranger J.

Clin Endocrinol (Oxf). 2009 Oct;71(4):507-11.PMID: 19751297 [PubMed - in process]Related articles

A high normal TSH is associated with the metabolic syndrome.

Ruhla S, Weickert MO, Arafat AM, Osterhoff M, Isken F, Spranger J, Schöfl C, Pfeiffer AF, Möhlig M.

Clin Endocrinol (Oxf). 2009 Sep 10. [Epub ahead of print]PMID: 19744102 [PubMed - as supplied by publisher]Related articles

Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs.

Tönjes A, Koriath M, Schleinitz D, Dietrich K, Böttcher Y, Rayner NW, Almgren P, Enigk B, Richter O, Rohm S, Fischer-Rosinsky A, Pfeiffer A, Hoffmann K, Krohn K, Aust G, Spranger J, Groop L, Blüher M, Kovacs P, Stumvoll M.

Hum Mol Genet. 2009 Dec 1;18(23):4662-8. Epub 2009 Sep 3.PMID: 19729412 [PubMed - in process]Related articlesFree article

[Depot insulin with tumor risk. Changing now or staying cool? (interview by Sarah Pampel)]

Spranger J.

MMW Fortschr Med. 2009 Jul 23;151(30-33):22. German. No abstract available. PMID: 19722454 [PubMed - indexed for MEDLINE]Related articles

Mutations in MMP9 and MMP13 determine the mode of inheritance and the clinical spectrum of metaphyseal anadysplasia.

Lausch E, Keppler R, Hilbert K, Cormier-Daire V, Nikkel S, Nishimura G, Unger S, Spranger J, Superti-Furga A, Zabel B.

Am J Hum Genet. 2009 Aug;85(2):168-78. Epub 2009 Jul 16. Erratum in: Am J Hum Genet. 2009 Sep;85(3):420. PMID: 19615667 [PubMed - indexed for MEDLINE]Related articles

Factors that influence retinol-binding protein 4-transthyretin interaction are not altered in overweight subjects and overweight subjects with type 2 diabetes mellitus.

Frey SK, Spranger J, Henze A, Pfeiffer AF, Schweigert FJ, Raila J.

Metabolism. 2009 Oct;58(10):1386-92. Epub 2009 Jun 18.PMID: 19501859 [PubMed - indexed for MEDLINE]Related articles

Free fatty acids link metabolism and regulation of the insulin-sensitizing fibroblast growth factor-21.

Mai K, Andres J, Biedasek K, Weicht J, Bobbert T, Sabath M, Meinus S, Reinecke F, Möhlig M, Weickert MO, Clemenz M, Pfeiffer AF, Kintscher U, Spuler S, Spranger J.

Diabetes. 2009 Jul;58(7):1532-8. Epub 2009 Apr 28.PMID: 19401423 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of potentised substances on growth rate of the water plant Lemna gibba L.

Scherr C, Simon M, Spranger J, Baumgartner S.

Complement Ther Med. 2009 Apr;17(2):63-70. Epub 2009 Jan 7.PMID: 19185263 [PubMed - indexed for MEDLINE]Related articles

TBX15 mutations cause craniofacial dysmorphism, hypoplasia of scapula and pelvis, and short stature in Cousin syndrome.

Lausch E, Hermanns P, Farin HF, Alanay Y, Unger S, Nikkel S, Steinwender C, Scherer G, Spranger J, Zabel B, Kispert A, Superti-Furga A.

Am J Hum Genet. 2008 Nov;83(5):649-55.PMID: 19068278 [PubMed - indexed for MEDLINE]Related articlesFree article

Lack of association between the tagging SNP A+930-->G of SOCS3 and type 2 diabetes mellitus: meta-analysis of four independent study populations.

Fischer-Rosinsky A, Fisher E, Kovacs P, Blüher M, Möhlig M, Pfeiffer AF, Boeing H, Spranger J.

PLoS One. 2008;3(12):e3852. Epub 2008 Dec 4.PMID: 19052638 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence that kidney function but not type 2 diabetes determines retinol-binding protein 4 serum levels.

Henze A, Frey SK, Raila J, Tepel M, Scholze A, Pfeiffer AF, Weickert MO, Spranger J, Schweigert FJ.

Diabetes. 2008 Dec;57(12):3323-6. Epub 2008 Sep 16.PMID: 18796616 [PubMed - indexed for MEDLINE]Related articlesFree article

Test system stability and natural variability of a Lemna gibba L. bioassay.

Scherr C, Simon M, Spranger J, Baumgartner S.

PLoS One. 2008 Sep 4;3(9):e3133.PMID: 18769541 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acids differentially modify the expression of urokinase type plasminogen activator receptor in monocytes.

Assmann A, Möhlig M, Osterhoff M, Pfeiffer AF, Spranger J.

Biochem Biophys Res Commun. 2008 Nov 7;376(1):196-9. Epub 2008 Aug 30.PMID: 18762175 [PubMed - indexed for MEDLINE]Related articles

Influences of levodopa on adipose tissue and skeletal muscle metabolism in patients with idiopathic Parkinson's disease.

Adams F, Boschmann M, Lobsien E, Kupsch A, Lipp A, Franke G, Leisse MC, Janke J, Gottschalk S, Spranger J, Jordan J.

Eur J Clin Pharmacol. 2008 Sep;64(9):863-70. Epub 2008 Jul 30.PMID: 18665357 [PubMed - indexed for MEDLINE]Related articles

Intravenous lipid and heparin infusion-induced elevation in free fatty acids and triglycerides modifies circulating androgen levels in women: a randomized, controlled trial.

Mai K, Bobbert T, Reinecke F, Andres J, Maser-Gluth C, Wudy SA, Möhlig M, Weickert MO, Hartmann MF, Schulte HM, Diederich S, Pfeiffer AF, Spranger J.

J Clin Endocrinol Metab. 2008 Oct;93(10):3900-6. Epub 2008 Jul 29.PMID: 18664538 [PubMed - indexed for MEDLINE]Related articlesFree article

Congenital joint dislocations caused by carbohydrate sulfotransferase 3 deficiency in recessive Larsen syndrome and humero-spinal dysostosis.

Hermanns P, Unger S, Rossi A, Perez-Aytes A, Cortina H, Bonafé L, Boccone L, Setzu V, Dutoit M, Sangiorgi L, Pecora F, Reicherter K, Nishimura G, Spranger J, Zabel B, Superti-Furga A.

Am J Hum Genet. 2008 Jun;82(6):1368-74. Erratum in: Am J Hum Genet. 2008 Aug;83(2):293. PMID: 18513679 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma resistin levels and risk of myocardial infarction and ischemic stroke.

Weikert C, Westphal S, Berger K, Dierkes J, Möhlig M, Spranger J, Rimm EB, Willich SN, Boeing H, Pischon T.

J Clin Endocrinol Metab. 2008 Jul;93(7):2647-53. Epub 2008 May 6.PMID: 18460562 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of euglycemic hyperinsulinemia and lipid infusion on circulating cholecystokinin.

Weickert MO, Möhlig M, Spranger J, Schöfl C, Loeffelholz CV, Riepl RL, Otto B, Pfeiffer AF.

J Clin Endocrinol Metab. 2008 Jun;93(6):2328-33. Epub 2008 Mar 25.PMID: 18364380 [PubMed - indexed for MEDLINE]Related articlesFree article

Euglycemic hyperinsulinemia differentially modulates circulating total and acylated-ghrelin in humans.

Weickert MO, Loeffelholz CV, Arafat AM, Schöfl C, Otto B, Spranger J, Möhlig M, Pfeiffer AF.

J Endocrinol Invest. 2008 Feb;31(2):119-24.PMID: 18362502 [PubMed - indexed for MEDLINE]Related articles

Retinol-binding protein 4 is associated with insulin resistance, but appears unsuited for metabolic screening in women with polycystic ovary syndrome.

Möhlig M, Weickert MO, Ghadamgahi E, Arafat AM, Spranger J, Pfeiffer AF, Schöfl C.

Eur J Endocrinol. 2008 Apr;158(4):517-23.PMID: 18362299 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical and radiographic delineation of odontochondrodysplasia.

Unger S, Antoniazzi F, Brugnara M, Alanay Y, Caglayan A, Lachlan K, Ikegawa S, Nishimura G, Zabel B, Spranger J, Superti-Furga A.

Am J Med Genet A. 2008 Mar 15;146A(6):770-8.PMID: 18241073 [PubMed - indexed for MEDLINE]Related articles

Growth hormone response during oral glucose tolerance test: the impact of assay method on the estimation of reference values in patients with acromegaly and in healthy controls, and the role of gender, age, and body mass index.

Arafat AM, Möhlig M, Weickert MO, Perschel FH, Purschwitz J, Spranger J, Strasburger CJ, Schöfl C, Pfeiffer AF.

J Clin Endocrinol Metab. 2008 Apr;93(4):1254-62. Epub 2008 Jan 2.PMID: 18171702 [PubMed - indexed for MEDLINE]Related articlesFree article

Duckweed (Lemna gibba L.) as a test organism for homeopathic potencies.

Scherr C, Simon M, Spranger J, Baumgartner S.

J Altern Complement Med. 2007 Nov;13(9):931-7.PMID: 18047439 [PubMed - indexed for MEDLINE]Related articles

Identification of a functional protein kinase Cbeta promoter polymorphism in humans related to insulin resistance.

Osterhoff MA, Heuer S, Pfeiffer M, Tasic J, Kaiser S, Isken F, Spranger J, Weickert MO, Möhlig M, Pfeiffer AF.

Mol Genet Metab. 2008 Feb;93(2):210-5. Epub 2007 Oct 22.PMID: 17950644 [PubMed - indexed for MEDLINE]Related articles

Cell-type specific regulation of the human 11beta-hydroxysteroid dehydrogenase type 1 promoter.

Andres J, Mai K, Möhlig M, Weickert MO, Bumke-Vogt C, Diederich S, Pfeiffer AF, Bähr V, Spranger J.

Arch Physiol Biochem. 2007 Jun;113(3):110-5.PMID: 17922306 [PubMed - indexed for MEDLINE]Related articles

KCNJ11 E23K affects diabetes risk and is associated with the disposition index: results of two independent German cohorts.

Fischer A, Fisher E, Möhlig M, Schulze M, Hoffmann K, Weickert MO, Schueler R, Osterhoff M, Pfeiffer AF, Boeing H, Spranger J.

Diabetes Care. 2008 Jan;31(1):87-9. Epub 2007 Sep 26. No abstract available. PMID: 17898091 [PubMed - indexed for MEDLINE]Related articlesFree article

B vitamin plasma levels and the risk of ischemic stroke and transient ischemic attack in a German cohort.

Weikert C, Dierkes J, Hoffmann K, Berger K, Drogan D, Klipstein-Grobusch K, Spranger J, Möhlig M, Luley C, Boeing H.

Stroke. 2007 Nov;38(11):2912-8. Epub 2007 Sep 20.PMID: 17885260 [PubMed - indexed for MEDLINE]Related articlesFree article

A Thr94Ala mutation in human liver fatty acid-binding protein contributes to reduced hepatic glycogenolysis and blunted elevation of plasma glucose levels in lipid-exposed subjects.

Weickert MO, Loeffelholz CV, Roden M, Chandramouli V, Brehm A, Nowotny P, Osterhoff MA, Isken F, Spranger J, Landau BR, Pfeiffer AF, Möhlig M.

Am J Physiol Endocrinol Metab. 2007 Oct;293(4):E1078-84. Epub 2007 Aug 14.PMID: 17698986 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma pyridoxal-5-phosphate and future risk of myocardial infarction in the European Prospective Investigation into Cancer and Nutrition Potsdam cohort.

Dierkes J, Weikert C, Klipstein-Grobusch K, Westphal S, Luley C, Möhlig M, Spranger J, Boeing H.

Am J Clin Nutr. 2007 Jul;86(1):214-20.PMID: 17616783 [PubMed - indexed for MEDLINE]Related articlesFree article

Microalbuminuria is a major determinant of elevated plasma retinol-binding protein 4 in type 2 diabetic patients.

Raila J, Henze A, Spranger J, Möhlig M, Pfeiffer AF, Schweigert FJ.

Kidney Int. 2007 Aug;72(4):505-11. Epub 2007 Jun 13.PMID: 17568782 [PubMed - indexed for MEDLINE]Related articles

Association of prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism with type 2 diabetes in two German study populations.

Nitz I, Fisher E, Grallert H, Li Y, Gieger C, Rubin D, Boeing H, Spranger J, Lindner I, Schreiber S, Rathmann W, Gohlke H, Döring A, Wichmann HE, Schrezenmeir J, Döring F, Illig T.

J Clin Endocrinol Metab. 2007 Aug;92(8):3183-8. Epub 2007 Jun 12.PMID: 17566096 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of relative and attributable risk of myocardial infarction and stroke according to C-reactive protein and low-density lipoprotein cholesterol levels.

Pischon T, Möhlig M, Hoffmann K, Spranger J, Weikert C, Willich SN, Pfeiffer AF, Boeing H.

Eur J Epidemiol. 2007;22(7):429-38. Epub 2007 Jun 8.PMID: 17557140 [PubMed - indexed for MEDLINE]Related articles

Rosiglitazone decreases 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue.

Mai K, Andres J, Bobbert T, Maser-Gluth C, Möhlig M, Bähr V, Pfeiffer AF, Spranger J, Diederich S.

Clin Endocrinol (Oxf). 2007 Sep;67(3):419-25. Epub 2007 Jun 6.PMID: 17555498 [PubMed - in process]Related articles

Short-term therapy with atorvastatin or fenofibrate does not affect plasma ghrelin, resistin or adiponectin levels in type 2 diabetic patients with mixed hyperlipoproteinaemia.

Otto C, Otto B, Frost RJ, Vogeser M, Pfeiffer AF, Spranger J, Parhofer KG.

Acta Diabetol. 2007 Jun;44(2):65-8. Epub 2007 May 27.PMID: 17530469 [PubMed - indexed for MEDLINE]Related articles

Effects of pronounced weight loss on adiponectin oligomer composition and metabolic parameters.

Engl J, Bobbert T, Ciardi C, Laimer M, Tatarczyk T, Kaser S, Weiss H, Molnar C, Tilg H, Patsch JR, Spranger J, Ebenbichler CF.

Obesity (Silver Spring). 2007 May;15(5):1172-8.PMID: 17495193 [PubMed - indexed for MEDLINE]Related articles

The effect of moderate alcohol consumption on adiponectin oligomers and muscle oxidative capacity: a human intervention study.

Beulens JW, van Loon LJ, Kok FJ, Pelsers M, Bobbert T, Spranger J, Helander A, Hendriks HF.

Diabetologia. 2007 Jul;50(7):1388-92. Epub 2007 May 11.PMID: 17492425 [PubMed - indexed for MEDLINE]Related articlesFree article

L-FABP T94A is associated with fasting triglycerides and LDL-cholesterol in women.

Fisher E, Weikert C, Klapper M, Lindner I, Möhlig M, Spranger J, Boeing H, Schrezenmeir J, Döring F.

Mol Genet Metab. 2007 Jul;91(3):278-84. Epub 2007 May 7.PMID: 17485234 [PubMed - indexed for MEDLINE]Related articles

An accurate risk score based on anthropometric, dietary, and lifestyle factors to predict the development of type 2 diabetes.

Schulze MB, Hoffmann K, Boeing H, Linseisen J, Rohrmann S, Möhlig M, Pfeiffer AF, Spranger J, Thamer C, Häring HU, Fritsche A, Joost HG.

Diabetes Care. 2007 Mar;30(3):510-5.PMID: 17327313 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin oligomers in human serum during acute and chronic exercise: relation to lipid metabolism and insulin sensitivity.

Bobbert T, Wegewitz U, Brechtel L, Freudenberg M, Mai K, Möhlig M, Diederich S, Ristow M, Rochlitz H, Pfeiffer AF, Spranger J.

Int J Sports Med. 2007 Jan;28(1):1-8. Epub 2006 Nov 28.PMID: 17133288 [PubMed - indexed for MEDLINE]Related articles

Preselection of cases through expert clinical and radiological review significantly increases mutation detection rate in multiple epiphyseal dysplasia.

Zankl A, Jackson GC, Crettol LM, Taylor J, Elles R, Mortier GR, Spranger J, Zabel B, Unger S, Merrer ML, Cormier-Daire V, Hall CM, Wright MJ, Bonafe L, Superti-Furga A, Briggs MD.

Eur J Hum Genet. 2007 Feb;15(2):150-4. Epub 2006 Nov 29.PMID: 17133256 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of human body weight changes on circulating levels of peptide YY and peptide YY3-36.

Pfluger PT, Kampe J, Castaneda TR, Vahl T, D'Alessio DA, Kruthaupt T, Benoit SC, Cuntz U, Rochlitz HJ, Moehlig M, Pfeiffer AF, Koebnick C, Weickert MO, Otto B, Spranger J, Tschöp MH.

J Clin Endocrinol Metab. 2007 Feb;92(2):583-8. Epub 2006 Nov 21.PMID: 17119001 [PubMed - indexed for MEDLINE]Related articlesFree article

Arabinoxylan fibre consumption improved glucose metabolism, but did not affect serum adipokines in subjects with impaired glucose tolerance.

Garcia AL, Steiniger J, Reich SC, Weickert MO, Harsch I, Machowetz A, Mohlig M, Spranger J, Rudovich NN, Meuser F, Doerfer J, Katz N, Speth M, Zunft HJ, Pfeiffer AH, Koebnick C.

Horm Metab Res. 2006 Nov;38(11):761-6.PMID: 17111305 [PubMed - indexed for MEDLINE]Related articles

Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety.

Weickert MO, Spranger J, Holst JJ, Otto B, Koebnick C, Möhlig M, Pfeiffer AF.

Br J Nutr. 2006 Nov;96(5):795-8.PMID: 17092365 [PubMed - indexed for MEDLINE]Related articles

Effects of potentised substances on growth kinetics of Saccharomyces cerevisiae and Schizosaccharomyces pombe.

Scherr C, Baumgartner S, Spranger J, Simon M.

Forsch Komplementmed. 2006 Oct;13(5):298-306. Epub 2006 Oct 20.PMID: 17057391 [PubMed - indexed for MEDLINE]Related articles

IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies.

Huth C, Heid IM, Vollmert C, Gieger C, Grallert H, Wolford JK, Langer B, Thorand B, Klopp N, Hamid YH, Pedersen O, Hansen T, Lyssenko V, Groop L, Meisinger C, Döring A, Löwel H, Lieb W, Hengstenberg C, Rathmann W, Martin S, Stephens JW, Ireland H, Mather H, Miller GJ, Stringham HM, Boehnke M, Tuomilehto J, Boeing H, Möhlig M, Spranger J, Pfeiffer A, Wernstedt I, Niklason A, López-Bermejo A, Fernández-Real JM, Hanson RL, Gallart L, Vendrell J, Tsiavou A, Hatziagelaki E, Humphries SE, Wichmann HE, Herder C, Illig T.

Diabetes. 2006 Oct;55(10):2915-21.PMID: 17003362 [PubMed - indexed for MEDLINE]Related articlesFree article

Predicting impaired glucose metabolism in women with polycystic ovary syndrome by decision tree modelling.

Möhlig M, Flöter A, Spranger J, Weickert MO, Schill T, Schlösser HW, Brabant G, Pfeiffer AF, Selbig J, Schöfl C.

Diabetologia. 2006 Nov;49(11):2572-9. Epub 2006 Sep 14.PMID: 16972044 [PubMed - indexed for MEDLINE]Related articles

No effect of free fatty acids on adrenocorticotropin and cortisol secretion in healthy young men.

Mai K, Bobbert T, Kullmann V, Andres J, Bähr V, Maser-Gluth C, Rochlitz H, Spranger J, Diederich S, Pfeiffer AF.

Metabolism. 2006 Aug;55(8):1022-8.PMID: 16839836 [PubMed - indexed for MEDLINE]Related articles