PubMed

Genetic evidence that raised Sex Hormone Binding Globulin (SHBG) levels reduce the risk of type 2 diabetes.

Perry JR, Weedon MN, Langenberg C, Jackson AU, Lyssenko V, Sparsø T, Thorleifsson G, Grallert H, Ferrucci L, Maggio M, Paolisso G, Walker M, Palmer CN, Payne F, Young E, Herder C, Narisu N, Morken MA, Bonnycastle LL, Owen KR, Shields B, Knight B, Bennett A, Groves CJ, Ruokonen A, Jarvelin MR, Pearson E, Pascoe L, Ferrannini E, Bornstein SR, Stringham HM, Scott LJ, Kuusisto J, Nilsson P, Neptin M, Gjesing AP, Pisinger C, Lauritzen T, Sandbaek A, Sampson M; MAGIC, Zeggini E, Lindgren CM, Steinthorsdottir V, Thorsteinsdottir U, Hansen T, Schwarz P, Illig T, Laakso M, Stefansson K, Morris AD, Groop L, Pedersen O, Boehnke M, Barroso I, Wareham NJ, Hattersley AT, McCarthy MI, Frayling TM.

Hum Mol Genet. 2009 Nov 18. [Epub ahead of print]PMID: 19933169 [PubMed - as supplied by publisher]

No consistent effect of ADRB2 haplotypes on obesity, hypertension and quantitative traits of body fatness and blood pressure among 6,514 adult danes.

Gjesing AP, Sparsø T, Borch-Johnsen K, Jørgensen T, Pedersen O, Hansen T, Olsen NV.

PLoS One. 2009 Sep 25;4(9):e7206.PMID: 19779622 [PubMed - in process]Related articlesFree article

Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction.

Sparsø T, Grarup N, Andreasen C, Albrechtsen A, Holmkvist J, Andersen G, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Madsbad S, Hansen T, Pedersen O.

Diabetologia. 2009 Jul;52(7):1308-14. Epub 2009 Apr 29.PMID: 19404609 [PubMed - indexed for MEDLINE]Related articles

G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans.

Sparsø T, Bonnefond A, Andersson E, Bouatia-Naji N, Holmkvist J, Wegner L, Grarup N, Gjesing AP, Banasik K, Cavalcanti-Proença C, Marchand M, Vaxillaire M, Charpentier G, Jarvelin MR, Tichet J, Balkau B, Marre M, Lévy-Marchal C, Faerch K, Borch-Johnsen K, Jørgensen T, Madsbad S, Poulsen P, Vaag A, Dina C, Hansen T, Pedersen O, Froguel P.

Diabetes. 2009 Jun;58(6):1450-6. Epub 2009 Mar 26.PMID: 19324940 [PubMed - indexed for MEDLINE]Related articlesFree article

A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk.

Bouatia-Naji N, Bonnefond A, Cavalcanti-Proença C, Sparsø T, Holmkvist J, Marchand M, Delplanque J, Lobbens S, Rocheleau G, Durand E, De Graeve F, Chèvre JC, Borch-Johnsen K, Hartikainen AL, Ruokonen A, Tichet J, Marre M, Weill J, Heude B, Tauber M, Lemaire K, Schuit F, Elliott P, Jørgensen T, Charpentier G, Hadjadj S, Cauchi S, Vaxillaire M, Sladek R, Visvikis-Siest S, Balkau B, Lévy-Marchal C, Pattou F, Meyre D, Blakemore AI, Jarvelin MR, Walley AJ, Hansen T, Dina C, Pedersen O, Froguel P.

Nat Genet. 2009 Jan;41(1):89-94. Epub 2008 Dec 7.PMID: 19060909 [PubMed - indexed for MEDLINE]Related articles

Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation.

Sparsø T, Andersen G, Albrechtsen A, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Wasson J, Permutt MA, Glaser B, Madsbad S, Pedersen O, Hansen T.

Diabetologia. 2008 Sep;51(9):1646-52. Epub 2008 Jun 21.PMID: 18568334 [PubMed - indexed for MEDLINE]Related articles

AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects.

Andersen G, Burgdorf KS, Sparsø T, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabetes. 2008 May;57(5):1427-32. Epub 2008 Mar 3.PMID: 18316360 [PubMed - indexed for MEDLINE]Related articlesFree article

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes.

Sparsø T, Andersen G, Nielsen T, Burgdorf KS, Gjesing AP, Nielsen AL, Albrechtsen A, Rasmussen SS, Jørgensen T, Borch-Johnsen K, Sandbaek A, Lauritzen T, Madsbad S, Hansen T, Pedersen O.

Diabetologia. 2008 Jan;51(1):70-5. Epub 2007 Nov 16. Erratum in: Diabetologia. 2008 Feb;51(2):383. PMID: 18008060 [PubMed - indexed for MEDLINE]Related articles

Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites.

Sparsø T, Hussain MS, Borch-Johnsen K, Jørgensen T, Madsbad S, Hansen T, Pedersen O, Andersen G.

Mol Genet Metab. 2007 Nov;92(3):278-82. Epub 2007 Aug 2.PMID: 17681849 [PubMed - indexed for MEDLINE]Related articles

A -243A-->G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects.

Boesgaard TW, Castella SI, Andersen G, Albrechtsen A, Sparsø T, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabet Med. 2007 Jul;24(7):702-6. Epub 2007 Apr 24.PMID: 17459095 [PubMed - indexed for MEDLINE]Related articles

Common variation in LMNA increases susceptibility to type 2 diabetes and associates with elevated fasting glycemia and estimates of body fat and height in the general population: studies of 7,495 Danish whites.

Wegner L, Andersen G, Sparsø T, Grarup N, Glümer C, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabetes. 2007 Mar;56(3):694-8.PMID: 17327437 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middle-aged white people.

Sparsø T, Hussain MS, Andersen G, Hainerova I, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Mol Genet Metab. 2007 Feb;90(2):205-9. Epub 2006 Nov 28.PMID: 17129741 [PubMed - indexed for MEDLINE]Related articles

Large-scale study of the -232C > G polymorphism of PCK1 in Type 2 diabetes.

Wegner L, Andersen G, Albrechtsen A, Sparsø T, Glümer C, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Diabet Med. 2006 Oct;23(10):1140-4.PMID: 16978381 [PubMed - indexed for MEDLINE]Related articles

Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes.

Larsen LH, Rose CS, Sparsø T, Overgaard J, Torekov SS, Grarup N, Jensen DP, Albrechtsen A, Andersen G, Ek J, Glümer C, Borch-Johnsen K, Jørgensen T, Hansen T, Pedersen O.

Int J Obes (Lond). 2007 Feb;31(2):365-70. Epub 2006 Jun 6.PMID: 16755280 [PubMed - indexed for MEDLINE]Related articles

The possibility of discriminating within the Bacillus cereus group using gyrB sequencing and PCR-RFLP.

Jensen GB, Fisker N, Sparsø T, Andrup L.

Int J Food Microbiol. 2005 Sep 25;104(1):113-20.PMID: 16005534 [PubMed - indexed for MEDLINE]Related articles