PubMed

Exploring conformational modes of macromolecular assemblies by multiparticle cryo-EM.

Spahn CM, Penczek PA.

Curr Opin Struct Biol. 2009 Oct;19(5):623-31. Epub 2009 Sep 18. Review.PMID: 19767196 [PubMed - indexed for MEDLINE]Related articles

Navigating the ribosome's metastable energy landscape.

Munro JB, Sanbonmatsu KY, Spahn CM, Blanchard SC.

Trends Biochem Sci. 2009 Aug;34(8):390-400. Epub 2009 Aug 3. Review.PMID: 19647434 [PubMed - indexed for MEDLINE]Related articles

[Social support and physicians' health]

Voltmer E, Spahn C.

Z Psychosom Med Psychother. 2009;55(1):51-69. Review. German. PMID: 19353512 [PubMed - indexed for MEDLINE]Related articles

GTPase activation of elongation factor EF-Tu by the ribosome during decoding.

Schuette JC, Murphy FV 4th, Kelley AC, Weir JR, Giesebrecht J, Connell SR, Loerke J, Mielke T, Zhang W, Penczek PA, Ramakrishnan V, Spahn CM.

EMBO J. 2009 Mar 18;28(6):755-65. Epub 2009 Feb 19.PMID: 19229291 [PubMed - indexed for MEDLINE]Related articles

A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation.

Connell SR, Topf M, Qin Y, Wilson DN, Mielke T, Fucini P, Nierhaus KH, Spahn CM.

Nat Struct Mol Biol. 2008 Sep;15(9):910-5.PMID: 19172743 [PubMed - indexed for MEDLINE]Related articles

Heterogeneity of large macromolecular complexes revealed by 3D cryo-EM variance analysis.

Zhang W, Kimmel M, Spahn CM, Penczek PA.

Structure. 2008 Dec 10;16(12):1770-6.PMID: 19081053 [PubMed - indexed for MEDLINE]Related articles

Psychosocial health risk factors and resources of medical students and physicians: a cross-sectional study.

Voltmer E, Kieschke U, Schwappach DL, Wirsching M, Spahn C.

BMC Med Educ. 2008 Oct 2;8:46.PMID: 18831732 [PubMed - indexed for MEDLINE]Related articlesFree article

Quality of life and psychological distress in parents of children with a cochlear implant.

Spahn C, Burger T, Löschmann C, Richter B.

Cochlear Implants Int. 2004 Mar;5(1):13-27.PMID: 18792191 [PubMed - in process]Related articles

["Your child is hard of hearing" - a longitudinal study of parental distress]

Burger T, Löhle E, Richter B, Bengel J, Laszig R, Spahn C.

Laryngorhinootologie. 2008 Aug;87(8):552-9. German. PMID: 18654939 [PubMed - indexed for MEDLINE]Related articles

Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.

Harms JM, Wilson DN, Schluenzen F, Connell SR, Stachelhaus T, Zaborowska Z, Spahn CM, Fucini P.

Mol Cell. 2008 Apr 11;30(1):26-38.PMID: 18406324 [PubMed - indexed for MEDLINE]Related articles

[Psychosocial behaviour and subjective experience specific to the course of study of medical students in their first and fifth years of study]

Voltmer E, Kieschke U, Spahn C.

Gesundheitswesen. 2008 Feb;70(2):98-104. German. PMID: 18348099 [PubMed - indexed for MEDLINE]Related articles

Employment and acceptance of hearing protectors in classical symphony and opera orchestras.

Zander MF, Spahn C, Richter B.

Noise Health. 2008 Jan-Mar;10(38):14-26.PMID: 18270404 [PubMed - indexed for MEDLINE]Related articlesFree article

A dose-rate effect in single-particle electron microscopy.

Chen JZ, Sachse C, Xu C, Mielke T, Spahn CM, Grigorieff N.

J Struct Biol. 2008 Jan;161(1):92-100. Epub 2007 Oct 1.PMID: 17977018 [PubMed - indexed for MEDLINE]Related articlesFree article

[Work-related behavior and experience of physicians in the third to eighth year of their professional life]

Von Voltmer E, Kieschke U, Spahn C.

Z Psychosom Med Psychother. 2007;53(3):244-57. German. PMID: 17883932 [PubMed - indexed for MEDLINE]Related articles

Work-related behaviour and experience patterns of physicians compared to other professions.

Voltmer E, Kieschke U, Spahn C.

Swiss Med Wkly. 2007 Aug 11;137(31-32):448-53.PMID: 17705109 [PubMed - indexed for MEDLINE]Related articlesFree article

[Targeted management of challenging behavior in persons with dementia: the "Serial Trial Intervention" (STI)]

Fischer T, Spahn C, Kovach C.

Pflege Z. 2007 Jul;60(7):370-3. German. No abstract available. PMID: 17702149 [PubMed - indexed for MEDLINE]Related articles

Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors.

Connell SR, Takemoto C, Wilson DN, Wang H, Murayama K, Terada T, Shirouzu M, Rost M, Schüler M, Giesebrecht J, Dabrowski M, Mielke T, Fucini P, Yokoyama S, Spahn CM.

Mol Cell. 2007 Mar 9;25(5):751-64.PMID: 17349960 [PubMed - indexed for MEDLINE]Related articles

Structure of the ribosome-bound cricket paralysis virus IRES RNA.

Schüler M, Connell SR, Lescoute A, Giesebrecht J, Dabrowski M, Schroeer B, Mielke T, Penczek PA, Westhof E, Spahn CM.

Nat Struct Mol Biol. 2006 Dec;13(12):1092-6. Epub 2006 Nov 19.PMID: 17115051 [PubMed - indexed for MEDLINE]Related articles

Structure of eEF3 and the mechanism of transfer RNA release from the E-site.

Andersen CB, Becker T, Blau M, Anand M, Halic M, Balar B, Mielke T, Boesen T, Pedersen JS, Spahn CM, Kinzy TG, Andersen GR, Beckmann R.

Nature. 2006 Oct 12;443(7112):663-8. Epub 2006 Aug 23.PMID: 16929303 [PubMed - indexed for MEDLINE]Related articles

Building functional modules from molecular interactions.

Hofmann KP, Spahn CM, Heinrich R, Heinemann U.

Trends Biochem Sci. 2006 Sep;31(9):497-508. Epub 2006 Aug 4. Review. Erratum in: Trends Biochem Sci. 2006 Nov;31(11):613. PMID: 16890441 [PubMed - indexed for MEDLINE]Related articles

Psychic stress and quality of life in parents during decisive phases in the therapy of their hearing-impaired children.

Burger T, Spahn C, Richter B, Eissele S, Löhle E, Bengel J.

Ear Hear. 2006 Aug;27(4):313-20.PMID: 16825882 [PubMed - indexed for MEDLINE]Related articles

[Need for and use of a university clinic mental health liaison service]

Fritzsche K, Spahn C, Nübling M, Wirsching M.

Nervenarzt. 2007 Sep;78(9):1037-45. German. PMID: 16523354 [PubMed - indexed for MEDLINE]Related articles

A method of focused classification, based on the bootstrap 3D variance analysis, and its application to EF-G-dependent translocation.

Penczek PA, Frank J, Spahn CM.

J Struct Biol. 2006 May;154(2):184-94. Epub 2006 Feb 17. Review.PMID: 16520062 [PubMed - indexed for MEDLINE]Related articles

Estimation of variance in single-particle reconstruction using the bootstrap technique.

Penczek PA, Yang C, Frank J, Spahn CM.

J Struct Biol. 2006 May;154(2):168-83. Epub 2006 Feb 13.PMID: 16510296 [PubMed - indexed for MEDLINE]Related articles

Parental distress: the initial phase of hearing aid and cochlear implant fitting.

Burger T, Spahn C, Richter B, Eissele S, Löhle E, Bengel J.

Am Ann Deaf. 2005 Spring;150(1):5-10.PMID: 15969219 [PubMed - indexed for MEDLINE]Related articles

Localization and dynamic behavior of ribosomal protein L30e.

Halic M, Becker T, Frank J, Spahn CM, Beckmann R.

Nat Struct Mol Biol. 2005 May;12(5):467-8. Epub 2005 May 1.PMID: 15864315 [PubMed - indexed for MEDLINE]Related articles

The psychosocial evaluation of medically-ill inpatients - accordance between mental disorders and self-rated psychosocial distress.

Fritzsche K, Burger T, Hartmann A, Nübling M, Spahn C.

Psychosoc Med. 2005 Dec 15;2:Doc11.PMID: 19742063 [PubMed - in process]Related articlesFree article

Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM.

Sengupta J, Nilsson J, Gursky R, Spahn CM, Nissen P, Frank J.

Nat Struct Mol Biol. 2004 Oct;11(10):957-62. Epub 2004 Aug 29.PMID: 15334071 [PubMed - indexed for MEDLINE]Related articles

Cryo-EM visualization of a viral internal ribosome entry site bound to human ribosomes: the IRES functions as an RNA-based translation factor.

Spahn CM, Jan E, Mulder A, Grassucci RA, Sarnow P, Frank J.

Cell. 2004 Aug 20;118(4):465-75.PMID: 15315759 [PubMed - indexed for MEDLINE]Related articles

Visualization of ribosome-recycling factor on the Escherichia coli 70S ribosome: functional implications.

Agrawal RK, Sharma MR, Kiel MC, Hirokawa G, Booth TM, Spahn CM, Grassucci RA, Kaji A, Frank J.

Proc Natl Acad Sci U S A. 2004 Jun 15;101(24):8900-5. Epub 2004 Jun 3.PMID: 15178758 [PubMed - indexed for MEDLINE]Related articlesFree article

Palmar erythema due to topiramate.

Scheinfeld N, Spahn C.

J Drugs Dermatol. 2004 May-Jun;3(3):321-2.PMID: 15176170 [PubMed - indexed for MEDLINE]Related articles

A European focus on proteomics.

Spahn CM, Lehrach H, Jungblut PR.

Genome Biol. 2004;5(5):322. Epub 2004 Apr 16. No abstract available. PMID: 15128441 [PubMed - indexed for MEDLINE]Related articlesFree article

Structure of the signal recognition particle interacting with the elongation-arrested ribosome.

Halic M, Becker T, Pool MR, Spahn CM, Grassucci RA, Frank J, Beckmann R.

Nature. 2004 Feb 26;427(6977):808-14.PMID: 14985753 [PubMed - indexed for MEDLINE]Related articles

Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.

Spahn CM, Gomez-Lorenzo MG, Grassucci RA, Jørgensen R, Andersen GR, Beckmann R, Penczek PA, Ballesta JP, Frank J.

EMBO J. 2004 Mar 10;23(5):1008-19. Epub 2004 Feb 19.PMID: 14976550 [PubMed - indexed for MEDLINE]Related articlesFree article

[Operationalized psychodynamic diagnostics (OPD) in patients with central serous chorioretinopathy]

Spahn C, Wiek J, Burger T.

Psychother Psychosom Med Psychol. 2004 Feb;54(2):52-7. German. PMID: 14872391 [PubMed - indexed for MEDLINE]Related articles

An unbiased cDNA library prepared from isolated Aplysia sensory neuron processes is enriched for cytoskeletal and translational mRNAs.

Moccia R, Chen D, Lyles V, Kapuya E, E Y, Kalachikov S, Spahn CM, Frank J, Kandel ER, Barad M, Martin KC.

J Neurosci. 2003 Oct 15;23(28):9409-17.PMID: 14561869 [PubMed - indexed for MEDLINE]Related articlesFree article

A comparison between parents of children with cochlear implants and parents of children with hearing aids regarding parental distress and treatment expectations.

Spahn C, Richter B, Burger T, Löhle E, Wirsching M.

Int J Pediatr Otorhinolaryngol. 2003 Sep;67(9):947-55.PMID: 12907049 [PubMed - indexed for MEDLINE]Related articles

Structural analogues of the bimetallic reaction center in acetyl CoA synthase: a Ni--Ni model with bound CO.

Linck RC, Spahn CW, Rauchfuss TB, Wilson SR.

J Am Chem Soc. 2003 Jul 23;125(29):8700-1.PMID: 12862445 [PubMed - indexed for MEDLINE]Related articles

Psychosomatic liaison service in hematological oncology: need for psychotherapeutic interventions and their realization.

Fritzsche K, Struss Y, Stein B, Spahn C.

Hematol Oncol. 2003 Jun;21(2):83-9.PMID: 12802813 [PubMed - indexed for MEDLINE]Related articles

Psychosomatic aspects in patients with central serous chorioretinopathy.

Spahn C, Wiek J, Burger T, Hansen L.

Br J Ophthalmol. 2003 Jun;87(6):704-8.PMID: 12770965 [PubMed - indexed for MEDLINE]Related articlesFree article

The active 80S ribosome-Sec61 complex.

Beckmann R, Spahn CM, Frank J, Blobel G.

Cold Spring Harb Symp Quant Biol. 2001;66:543-54. Review. No abstract available. PMID: 12762056 [PubMed - indexed for MEDLINE]Related articles

An assay for local quality in cryo-electron micrographs of single particles.

Gao H, Spahn CM, Grassucci RA, Frank J.

Ultramicroscopy. 2002 Nov;93(2):169-78.PMID: 12425594 [PubMed - indexed for MEDLINE]Related articles

Psychosomatic liaison service in medicine - need for psychotherapeutic interventions and their realisation.

Spahn C, Becker B, Fritzsche K, Burger T, Blum HE, Wirsching M.

Swiss Med Wkly. 2002 Apr 6;132(13-14):166-73.PMID: 12070789 [PubMed - indexed for MEDLINE]Related articlesFree article

Codon-anticodon interaction at the P site is a prerequisite for tRNA interaction with the small ribosomal subunit.

Schäfer MA, Tastan AO, Patzke S, Blaha G, Spahn CM, Wilson DN, Nierhaus KH.

J Biol Chem. 2002 May 24;277(21):19095-105. Epub 2002 Feb 26.PMID: 11867615 [PubMed - indexed for MEDLINE]Related articlesFree article

Structure of the 80S ribosome from Saccharomyces cerevisiae--tRNA-ribosome and subunit-subunit interactions.

Spahn CM, Beckmann R, Eswar N, Penczek PA, Sali A, Blobel G, Frank J.

Cell. 2001 Nov 2;107(3):373-86.PMID: 11701127 [PubMed - indexed for MEDLINE]Related articles

Architecture of the protein-conducting channel associated with the translating 80S ribosome.

Beckmann R, Spahn CM, Eswar N, Helmers J, Penczek PA, Sali A, Frank J, Blobel G.

Cell. 2001 Nov 2;107(3):361-72.PMID: 11701126 [PubMed - indexed for MEDLINE]Related articles

Clinical profile and outcomes of obese patients in cardiac rehabilitation stratified according to National Heart, Lung, and Blood Institute criteria.

Bader DS, Maguire TE, Spahn CM, O'Malley CJ, Balady GJ.

J Cardiopulm Rehabil. 2001 Jul-Aug;21(4):210-7.PMID: 11508180 [PubMed - indexed for MEDLINE]Related articles

Localization of the ribosomal protection protein Tet(O) on the ribosome and the mechanism of tetracycline resistance.

Spahn CM, Blaha G, Agrawal RK, Penczek P, Grassucci RA, Trieber CA, Connell SR, Taylor DE, Nierhaus KH, Frank J.

Mol Cell. 2001 May;7(5):1037-45.PMID: 11389850 [PubMed - indexed for MEDLINE]Related articles

Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit.

Spahn CM, Kieft JS, Grassucci RA, Penczek PA, Zhou K, Doudna JA, Frank J.

Science. 2001 Mar 9;291(5510):1959-62.PMID: 11239155 [PubMed - indexed for MEDLINE]Related articlesFree article

The need for psychosocial support in parents with cochlear implanted children.

Spahn C, Richter B, Zschocke I, Löhle E, Wirsching M.

Int J Pediatr Otorhinolaryngol. 2001 Jan;57(1):45-53.PMID: 11165642 [PubMed - indexed for MEDLINE]Related articles