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Pharmacogenetics of D2 dopamine receptor gene in prolactin-secreting pituitary adenomas.

Filopanti M, Lania A, Spada A.

Expert Opin Drug Metab Toxicol. 2009 Nov 23. [Epub ahead of print]PMID: 19929252 [PubMed - as supplied by publisher]

Differential expression of microRNAs in human parathyroid carcinomas compared with normal parathyroid tissue.

Corbetta S, Vaira V, Guarnieri V, Scillitani A, Eller-Vainicher C, Ferrero S, Vicentini L, Chiodini I, Bisceglia M, Beck-Peccoz P, Bosari S, Spada A.

Endocr Relat Cancer. 2009 Nov 19. [Epub ahead of print]PMID: 19926710 [PubMed - as supplied by publisher]Related articles

Obstacles to influenza vaccination in the frail elderly receiving home care: the primary care physician's perspective.

Kherad O, Spada A, Zumwald C, Rutschmann OT.

Swiss Med Wkly. 2009 Oct 17;139(41-42):615-6. No abstract available. PMID: 19918701 [PubMed - in process]Related articlesFree article

Evolution of an Aggressive Prolactinoma into a Growth Hormone Secreting Pituitary Tumor Coincident with GNAS Gene Mutation.

Lania AG, Ferrero S, Pivonello R, Mantovani G, Peverelli E, Di Sarno A, Beck Peccoz P, Spada A, Colao A.

J Clin Endocrinol Metab. 2009 Nov 4. [Epub ahead of print]PMID: 19890024 [PubMed - as supplied by publisher]Related articles

Sporadic ALS has compartment-specific aberrant exon splicing and altered cell-matrix adhesion biology.

Rabin SJ, Kim JM, Baughn M, Libby RT, Kim YJ, Fan Y, Libby RT, La Spada A, Stone B, Ravits J.

Hum Mol Genet. 2009 Nov 13. [Epub ahead of print]PMID: 19864493 [PubMed - as supplied by publisher]Related articlesFree article

d3-growth hormone receptor polymorphism in acromegaly: effects on metabolic phenotype.

Montefusco L, Filopanti M, Ronchi CL, Olgiati L, La-Porta C, Losa M, Epaminonda P, Coletti F, Beck-Peccoz P, Spada A, Lania AG, Arosio M.

Clin Endocrinol (Oxf). 2009 Sep 10. [Epub ahead of print]PMID: 19744097 [PubMed - as supplied by publisher]Related articles

ALS motor phenotype heterogeneity, focality, and spread: deconstructing motor neuron degeneration.

Ravits JM, La Spada AR.

Neurology. 2009 Sep 8;73(10):805-11. Review.PMID: 19738176 [PubMed - indexed for MEDLINE]Related articles

An Unusual Case of Recurrent Autoimmune Hypophysitis.

Giavoli C, Ferrante E, Bergamaschi S, Ronchi CL, Lania AG, Spada A, Beck-Peccoz P.

Exp Clin Endocrinol Diabetes. 2009 Aug 18. [Epub ahead of print]PMID: 19691013 [PubMed - as supplied by publisher]Related articles

Trapping tyrosinase key active intermediate under turnover.

Spada A, Palavicini S, Monzani E, Bubacco L, Casella L.

Dalton Trans. 2009 Sep 7;(33):6468-71. Epub 2009 Jul 15.PMID: 19672489 [PubMed - indexed for MEDLINE]Related articles

Analysis of genetic variants of phosphodiesterase 11A in acromegalic patients.

Peverelli E, Ermetici F, Filopanti M, Elli FM, Ronchi CL, Mantovani G, Ferrero S, Bosari S, Beck-Peccoz P, Lania A, Spada A.

Eur J Endocrinol. 2009 Nov;161(5):687-94. Epub 2009 Aug 11.PMID: 19671705 [PubMed - indexed for MEDLINE]Related articles

Expression of parathyroid-specific genes in vascular endothelial progenitors of normal and tumoral parathyroid glands.

Corbetta S, Belicchi M, Pisati F, Meregalli M, Eller-Vainicher C, Vicentini L, Beck-Peccoz P, Spada A, Torrente Y.

Am J Pathol. 2009 Sep;175(3):1200-7. Epub 2009 Jul 30.PMID: 19644013 [PubMed - in process]Related articles

Autophagy activation and enhanced mitophagy characterize the Purkinje cells of pcd mice prior to neuronal death.

Chakrabarti L, Eng J, Ivanov N, Garden GA, La Spada AR.

Mol Brain. 2009 Jul 29;2(1):24.PMID: 19640278 [PubMed - in process]Related articlesFree article

The dopamine-somatostatin chimeric compound BIM-23A760 exerts antiproliferative and cytotoxic effects in human non-functioning pituitary tumors by activating ERK1/2 and p38 pathways.

Peverelli E, Olgiati L, Locatelli M, Magni P, Fustini MF, Frank G, Mantovani G, Beck-Peccoz P, Spada A, Lania A.

Cancer Lett. 2009 Jul 18. [Epub ahead of print]PMID: 19619936 [PubMed - as supplied by publisher]Related articles

WUS and STM homologs are linked to the expression of lateral dominance in the acaulescent Streptocarpus rexii (Gesneriaceae).

Mantegazza R, Tononi P, Möller M, Spada A.

Planta. 2009 Aug;230(3):529-42. Epub 2009 Jun 14.PMID: 19526368 [PubMed - indexed for MEDLINE]Related articles

High prevalence of simple kidney cysts in patients with primary hyperparathyroidism.

Corbetta S, Eller-Vainicher C, Vicentini L, Carnicelli S, Sardanelli F, Beck-Peccoz P, Spada A.

J Endocrinol Invest. 2009 Sep;32(8):690-4. Epub 2009 May 26.PMID: 19516087 [PubMed - in process]Related articles

Analysis of GNAS1 and PRKAR1A gene mutations in human cardiac myxomas not associated with multiple endocrine disorders.

Mantovani G, Bondioni S, Corbetta S, Menicanti L, Rubino B, Peverelli E, Labarile P, Dall'Asta C, Ambrosi B, Beck-Peccoz P, Lania AG, Spada A.

J Endocrinol Invest. 2009 Jun;32(6):501-4. Epub 2009 Apr 29.PMID: 19494712 [PubMed - in process]Related articles

G-protein and signalling in pituitary tumours.

Lania A, Spada A.

Horm Res. 2009 Apr;71 Suppl 2:95-100. Epub 2009 Apr 29. Review.PMID: 19407505 [PubMed - indexed for MEDLINE]Related articles

Development of selective nutrient deprivation as a system to study autophagy induction and regulation in neurons.

Young JE, La Spada AR.

Autophagy. 2009 May;5(4):555-7. Epub 2009 May 10.PMID: 19363305 [PubMed - indexed for MEDLINE]Related articles

Prevalence of GH deficiency in cured acromegalic patients: impact of different previous treatments.

Ronchi CL, Giavoli C, Ferrante E, Verrua E, Bergamaschi S, Ferrari DI, Corbetta S, Montefusco L, Arosio M, Ambrosi B, Spada A, Beck-Peccoz P.

Eur J Endocrinol. 2009 Jul;161(1):37-42. Epub 2009 Apr 7.PMID: 19351744 [PubMed - indexed for MEDLINE]Related articles

Characterization of intracellular signaling mediated by human somatostatin receptor 5: role of the DRY motif and the third intracellular loop.

Peverelli E, Lania AG, Mantovani G, Beck-Peccoz P, Spada A.

Endocrinology. 2009 Jul;150(7):3169-76. Epub 2009 Apr 2.PMID: 19342453 [PubMed - indexed for MEDLINE]Related articles

Sporadic and MEN1-related primary hyperparathyroidism: differences in clinical expression and severity.

Eller-Vainicher C, Chiodini I, Battista C, Viti R, Mascia ML, Massironi S, Peracchi M, D'Agruma L, Minisola S, Corbetta S, Cole DE, Spada A, Scillitani A.

J Bone Miner Res. 2009 Aug;24(8):1404-10.PMID: 19309299 [PubMed - indexed for MEDLINE]Related articles

Getting a handle on Huntington's disease: silencing neurodegeneration.

La Spada AR.

Nat Med. 2009 Mar;15(3):252-3. No abstract available. PMID: 19265826 [PubMed - indexed for MEDLINE]Related articles

Heart rate variability and drawing impairment in hypoxemic COPD.

Antonelli Incalzi R, Corsonello A, Trojano L, Pedone C, Acanfora D, Spada A, D'Addio G, Maestri R, Rengo F, Rengo G.

Brain Cogn. 2009 Jun;70(1):163-70. Epub 2009 Mar 3.PMID: 19261365 [PubMed - indexed for MEDLINE]Related articles

Transcranial Doppler ultrasonography in the assessment of cerebral circulation arrest: improving sensitivity by transcervical and transorbital carotid insonation and serial examinations.

Conti A, Iacopino DG, Spada A, Cardali SM, Giusa M, La Torre D, Campennì A, Penna O, Baldari S, Tomasello F.

Neurocrit Care. 2009;10(3):326-35. Epub 2009 Feb 24.PMID: 19238589 [PubMed - indexed for MEDLINE]Related articles

Polyglutamine-expanded androgen receptor truncation fragments activate a Bax-dependent apoptotic cascade mediated by DP5/Hrk.

Young JE, Garden GA, Martinez RA, Tanaka F, Sandoval CM, Smith AC, Sopher BL, Lin A, Fischbeck KH, Ellerby LM, Morrison RS, Taylor JP, La Spada AR.

J Neurosci. 2009 Feb 18;29(7):1987-97.PMID: 19228953 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase A regulatory subunits in human adipose tissue: decreased R2B expression and activity in adipocytes from obese subjects.

Mantovani G, Bondioni S, Alberti L, Gilardini L, Invitti C, Corbetta S, Zappa MA, Ferrero S, Lania AG, Bosari S, Beck-Peccoz P, Spada A.

Diabetes. 2009 Mar;58(3):620-6. Epub 2008 Dec 18.PMID: 19095761 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of the 206M polymorphic variant of the SLC26A6 gene encoding a Cl- oxalate transporter in patients with primary hyperparathyroidism.

Corbetta S, Eller-Vainicher C, Frigerio M, Valaperta R, Costa E, Vicentini L, Baccarelli A, Beck-Peccoz P, Spada A.

Eur J Endocrinol. 2009 Feb;160(2):283-8. Epub 2008 Nov 24.PMID: 19029225 [PubMed - indexed for MEDLINE]Related articles

Nutrient deprivation induces neuronal autophagy and implicates reduced insulin signaling in neuroprotective autophagy activation.

Young JE, Martinez RA, La Spada AR.

J Biol Chem. 2009 Jan 23;284(4):2363-73. Epub 2008 Nov 18.PMID: 19017649 [PubMed - indexed for MEDLINE]Related articles

CTCF cis-regulates trinucleotide repeat instability in an epigenetic manner: a novel basis for mutational hot spot determination.

Libby RT, Hagerman KA, Pineda VV, Lau R, Cho DH, Baccam SL, Axford MM, Cleary JD, Moore JM, Sopher BL, Tapscott SJ, Filippova GN, Pearson CE, La Spada AR.

PLoS Genet. 2008 Nov;4(11):e1000257. Epub 2008 Nov 14.PMID: 19008940 [PubMed - indexed for MEDLINE]Related articlesFree article

Acromegaly secondary to an incidentally discovered growth-hormone-releasing hormone secreting bronchial carcinoid tumour associated to a pituitary incidentaloma.

Verrua E, Ronchi CL, Ferrante E, Ferrari DI, Bergamaschi S, Ferrero S, Zatelli MC, Branca V, Spada A, Beck-Peccoz P, Lania AG.

Pituitary. 2008 Oct 23. [Epub ahead of print]PMID: 18946740 [PubMed - as supplied by publisher]Related articles

Correlation between cognitive impairment and dependence in hypoxemic COPD.

Antonelli-Incalzi R, Corsonello A, Trojano L, Acanfora D, Spada A, Izzo O, Rengo F.

J Clin Exp Neuropsychol. 2008 Feb;30(2):141-50.PMID: 18938666 [PubMed - indexed for MEDLINE]Related articles

Aryl hydrocarbon receptor-interacting protein and pituitary adenomas: a population-based study on subjects exposed to dioxin after the Seveso, Italy, accident.

Pesatori AC, Baccarelli A, Consonni D, Lania A, Beck-Peccoz P, Bertazzi PA, Spada A.

Eur J Endocrinol. 2008 Dec;159(6):699-703. Epub 2008 Sep 11.PMID: 18787049 [PubMed - indexed for MEDLINE]Related articles

[Metformin role in the treatment of type 2 diabetes in 2008]

Spada A, Philippe J.

Rev Med Suisse. 2008 Jun 4;4(160):1392-4, 1396-7. Review. French. PMID: 18630062 [PubMed - indexed for MEDLINE]Related articles

Androgen receptor function in motor neuron survival and degeneration.

Cary GA, La Spada AR.

Phys Med Rehabil Clin N Am. 2008 Aug;19(3):479-94, viii. Review.PMID: 18625411 [PubMed - indexed for MEDLINE]Related articles

The zinc-binding domain of Nna1 is required to prevent retinal photoreceptor loss and cerebellar ataxia in Purkinje cell degeneration (pcd) mice.

Chakrabarti L, Eng J, Martinez RA, Jackson S, Huang J, Possin DE, Sopher BL, La Spada AR.

Vision Res. 2008 Sep;48(19):1999-2005. Epub 2008 Jul 26.PMID: 18602413 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular pathogenesis and cellular pathology of spinocerebellar ataxia type 7 neurodegeneration.

Garden GA, La Spada AR.

Cerebellum. 2008;7(2):138-49. Review.PMID: 18418675 [PubMed - indexed for MEDLINE]Related articles

Long-term basal and dynamic evaluation of hypothalamic-pituitary-adrenal (HPA) axis in acromegalic patients.

Ronchi CL, Ferrante E, Rizzo E, Giavoli C, Verrua E, Bergamaschi S, Lania AG, Beck-Peccoz P, Spada A.

Clin Endocrinol (Oxf). 2008 Oct;69(4):608-12. Epub 2008 Apr 10.PMID: 18410544 [PubMed - indexed for MEDLINE]Related articles

Effect of 9-cis retinoic acid on dopamine D2 receptor expression in pituitary adenoma cells.

Bondioni S, Angioni AR, Corbetta S, Locatelli M, Ferrero S, Ferrante E, Mantovani G, Olgiati L, Beck-Peccoz P, Spada A, Lania AG.

Exp Biol Med (Maywood). 2008 Apr;233(4):439-46.PMID: 18367633 [PubMed - indexed for MEDLINE]Related articlesFree article

Dopamine D2 receptor gene polymorphisms and response to cabergoline therapy in patients with prolactin-secreting pituitary adenomas.

Filopanti M, Barbieri AM, Angioni AR, Colao A, Gasco V, Grottoli S, Peri A, Baglioni S, Fustini MF, Pigliaru F, Monte PD, Borretta G, Ambrosi B, Jaffrain-Rea ML, Gasperi M, Brogioni S, Cannavò S, Mantovani G, Beck-Peccoz P, Lania A, Spada A.

Pharmacogenomics J. 2008 Oct;8(5):357-63. Epub 2008 Mar 11.PMID: 18332900 [PubMed - indexed for MEDLINE]Related articles

Cognitive training is ineffective in hypoxemic COPD: a six-month randomized controlled trial.

Incalzi RA, Corsonello A, Trojano L, Pedone C, Acanfora D, Spada A, Izzo O, Rengo F.

Rejuvenation Res. 2008 Feb;11(1):239-50.PMID: 18279034 [PubMed - indexed for MEDLINE]Related articles

[Some behavioral characteristics of physicians desired by ambulatory patients. A pilot survey]

Tambone V, De Virgilio A, Paolini A, Paviglianiti A, Picconi F, Pietrapertosa G, Rega D, Ricciardi R, Spada A.

Clin Ter. 2007 Nov-Dec;158(6):497-503. Italian. PMID: 18265714 [PubMed - indexed for MEDLINE]Related articles

Exercise-induced effects on growth hormone levels are associated with ghrelin changes only in presence of prolonged exercise bouts in male athletes.

Sartorio A, Morpurgo P, Cappiello V, Agosti F, Marazzi N, Giordani C, Rigamonti AE, Muller EE, Spada A.

J Sports Med Phys Fitness. 2008 Mar;48(1):97-101.PMID: 18212716 [PubMed - indexed for MEDLINE]Related articles

Preliminary data on biochemical remission of acromegaly after somatostatin analogs withdrawal.

Ronchi CL, Rizzo E, Lania AG, Pivonello R, Grottoli S, Colao A, Ghigo E, Spada A, Arosio M, Beck-Peccoz P.

Eur J Endocrinol. 2008 Jan;158(1):19-25.PMID: 18166813 [PubMed - indexed for MEDLINE]Related articlesFree article

The third intracellular loop of the human somatostatin receptor 5 is crucial for arrestin binding and receptor internalization after somatostatin stimulation.

Peverelli E, Mantovani G, Calebiro D, Doni A, Bondioni S, Lania A, Beck-Peccoz P, Spada A.

Mol Endocrinol. 2008 Mar;22(3):676-88. Epub 2007 Dec 20.PMID: 18096696 [PubMed - indexed for MEDLINE]Related articlesFree article

Evaluation of proopiomelanocortin mRNA in the peripheral blood from patients with Cushing's syndrome of different origin.

Bondioni S, Mantovani G, Polentarutti N, Ambrosi B, Loli P, Peverelli E, Lania AG, Beck-Peccoz P, Spada A.

J Endocrinol Invest. 2007 Nov;30(10):828-32.PMID: 18075284 [PubMed - indexed for MEDLINE]Related articles

Visceral neuropathy and intestinal pseudo-obstruction in a murine model of a nuclear inclusion disease.

Clarke CM, Plata C, Cole B, Tsuchiya K, La Spada AR, Kapur RP.

Gastroenterology. 2007 Dec;133(6):1971-8. Epub 2007 Aug 21.PMID: 18054568 [PubMed - indexed for MEDLINE]Related articlesFree article

Spinocerebellar ataxia type 7 (SCA7): widespread brain damage in an adult-onset patient with progressive visual impairments in comparison with an adult-onset patient without visual impairments.

Rüb U, Brunt ER, Seidel K, Gierga K, Mooy CM, Kettner M, Van Broeckhoven C, Bechmann I, La Spada AR, Schöls L, den Dunnen W, de Vos RA, Deller T.

Neuropathol Appl Neurobiol. 2008 Apr;34(2):155-68. Epub 2007 Oct 26.PMID: 17971076 [PubMed - indexed for MEDLINE]Related articles

Clinical usefulness of gastric-juice analysis in 2007: the stone that the builders rejected has become the cornerstone.

Tucci A, Bisceglia M, Rugge M, Tucci P, Marchegiani A, Papadopoli G, Spada A, Villani A, Pennelli G, Fusaroli P, Caravelli G, Catalano T, Cennamo V, Cianci M, De Fanis C, Fabbri C, Feliciangeli G, Gizzi G, Spadaccini A, Caletti G.

Gastrointest Endosc. 2007 Nov;66(5):881-90.PMID: 17963873 [PubMed - indexed for MEDLINE]Related articles

Genetic abnormalities of somatostatin receptors in pituitary tumors.

Lania A, Mantovani G, Spada A.

Mol Cell Endocrinol. 2008 May 14;286(1-2):180-6. Epub 2007 Aug 31. Review.PMID: 17913341 [PubMed - indexed for MEDLINE]Related articles

High expression of PKA regulatory subunit 1A protein is related to proliferation of human melanoma cells.

Mantovani G, Bondioni S, Lania AG, Rodolfo M, Peverelli E, Polentarutti N, Veliz Rodriguez T, Ferrero S, Bosari S, Beck-Peccoz P, Spada A.

Oncogene. 2008 Mar 20;27(13):1834-43. Epub 2007 Oct 1.PMID: 17906691 [PubMed - indexed for MEDLINE]Related articles