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Thiazide Diuretics Alone or With {beta}-Blockers Impair Glucose Metabolism in Hypertensive Patients With Abdominal Obesity.

Manrique C, Johnson M, Sowers JR.

Hypertension. 2009 Nov 16. [Epub ahead of print] No abstract available. PMID: 19917873 [PubMed - as supplied by publisher]Related articles

Obesity is associated with increased parathyroid hormone levels independent of glomerular filtration rate in chronic kidney disease.

Saab G, Whaley-Connell A, McFarlane SI, Li S, Chen SC, Sowers JR, McCullough PA, Bakris GL; Kidney Early Evaluation Program Investigators.

Metabolism. 2009 Oct 1. [Epub ahead of print]PMID: 19800639 [PubMed - as supplied by publisher]Related articles

Joint publication of journal of the CardioMetabolic Syndrome and the Journal of Clinical Hypertension.

Sowers JR.

J Clin Hypertens (Greenwich). 2009 Sep;11(9):504. No abstract available. PMID: 19751465 [PubMed - in process]Related articles

Hypertension and insulin resistance.

Whaley-Connell A, Sowers JR.

Hypertension. 2009 Sep;54(3):462-4. Epub 2009 Jul 27. No abstract available. PMID: 19635987 [PubMed - indexed for MEDLINE]Related articles

Rosuvastatin ameliorates the development of pulmonary arterial hypertension in the transgenic (mRen2)27 rat.

DeMarco VG, Habibi J, Whaley-Connell AT, Schneider RI, Sowers JR, Andresen BT, Gutweiler AA, Ma L, Johnson MS, Ferrario CM, Dellsperger KC.

Am J Physiol Heart Circ Physiol. 2009 Sep;297(3):H1128-39. Epub 2009 Jul 24.PMID: 19633211 [PubMed - indexed for MEDLINE]Related articles

Utility of aspirin therapy in patients with the cardiometabolic syndrome and diabetes.

Gardner M, Palmer J, Manrique C, Lastra G, Gardner DW, Sowers JR.

J Cardiometab Syndr. 2009 Spring;4(2):96-101. Review.PMID: 19614796 [PubMed - indexed for MEDLINE]Related articles

Nebivolol reduces proteinuria and renal NADPH oxidase-generated reactive oxygen species in the transgenic Ren2 rat.

Whaley-Connell A, Habibi J, Johnson M, Tilmon R, Rehmer N, Rehmer J, Wiedmeyer C, Ferrario CM, Sowers JR.

Am J Nephrol. 2009;30(4):354-60. Epub 2009 Jul 17.PMID: 19609077 [PubMed - in process]Related articles

Realities of newer beta-blockers for the management of hypertension.

Manrique C, Giles TD, Ferdinand KC, Sowers JR.

J Clin Hypertens (Greenwich). 2009 Jul;11(7):369-75. Review.PMID: 19583633 [PubMed - indexed for MEDLINE]Related articles

Evolving mechanisms of action of beta blockers: focus on nebivolol.

Mason RP, Giles TD, Sowers JR.

J Cardiovasc Pharmacol. 2009 Aug;54(2):123-8.PMID: 19528811 [PubMed - in process]Related articles

Nebivolol in obese and non-obese hypertensive patients.

Manrique C, Whaley-Connell A, Sowers JR.

J Clin Hypertens (Greenwich). 2009 Jun;11(6):309-15.PMID: 19527321 [PubMed - indexed for MEDLINE]Related articles

Effect of ethnicity on the progression of diabetic kidney disease independent of glycemic control.

Salifu MO, Shah S, Iqbal MH, Nabi M, Hayat A, Whaley-Connell AT, Sowers JR, McFarlane SI.

Am J Nephrol. 2009;30(3):261-7. Epub 2009 Jun 4.PMID: 19494485 [PubMed - in process]Related articles

Narrative review: the emerging clinical implications of the role of aldosterone in the metabolic syndrome and resistant hypertension.

Sowers JR, Whaley-Connell A, Epstein M.

Ann Intern Med. 2009 Jun 2;150(11):776-83. Review.PMID: 19487712 [PubMed - indexed for MEDLINE]Related articlesFree article

Angiotensin receptor blockers for the reduction of proteinuria in diabetic patients with overt nephropathy: results from the AMADEO study.

Bichu P, Nistala R, Khan A, Sowers JR, Whaley-Connell A.

Vasc Health Risk Manag. 2009;5(1):129-40. Epub 2009 Apr 8. Review.PMID: 19436679 [PubMed - indexed for MEDLINE]Related articlesFree article

The renin angiotensin aldosterone system in hypertension: roles of insulin resistance and oxidative stress.

Manrique C, Lastra G, Gardner M, Sowers JR.

Med Clin North Am. 2009 May;93(3):569-82. Review.PMID: 19427492 [PubMed - indexed for MEDLINE]Related articles

Mechanisms of base selection by human single-stranded selective monofunctional uracil-DNA glycosylase.

Darwanto A, Theruvathu JA, Sowers JL, Rogstad DK, Pascal T, Goddard W 3rd, Sowers LC.

J Biol Chem. 2009 Jun 5;284(23):15835-46. Epub 2009 Mar 25.PMID: 19324873 [PubMed - indexed for MEDLINE]Related articles

Diabetes mellitus and CKD awareness: the Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES).

Whaley-Connell A, Sowers JR, McCullough PA, Roberts T, McFarlane SI, Chen SC, Li S, Wang C, Collins AJ, Bakris GL; KEEP Investigators.

Am J Kidney Dis. 2009 Apr;53(4 Suppl 4):S11-21.PMID: 19285607 [PubMed - indexed for MEDLINE]Related articles

Mineralocorticoid receptor antagonism attenuates glomerular filtration barrier remodeling in the transgenic Ren2 rat.

Whaley-Connell A, Habibi J, Wei Y, Gutweiler A, Jellison J, Wiedmeyer CE, Ferrario CM, Sowers JR.

Am J Physiol Renal Physiol. 2009 May;296(5):F1013-22. Epub 2009 Mar 4.PMID: 19261739 [PubMed - indexed for MEDLINE]Related articles

Oxidative stress-mediated mitochondrial dysfunction contributes to angiotensin II-induced nonalcoholic fatty liver disease in transgenic Ren2 rats.

Wei Y, Clark SE, Thyfault JP, Uptergrove GM, Li W, Whaley-Connell AT, Ferrario CM, Sowers JR, Ibdah JA.

Am J Pathol. 2009 Apr;174(4):1329-37. Epub 2009 Feb 26.PMID: 19246643 [PubMed - indexed for MEDLINE]Related articlesFree article

Direct renin inhibition improves systemic insulin resistance and skeletal muscle glucose transport in a transgenic rodent model of tissue renin overexpression.

Lastra G, Habibi J, Whaley-Connell AT, Manrique C, Hayden MR, Rehmer J, Patel K, Ferrario C, Sowers JR.

Endocrinology. 2009 Jun;150(6):2561-8. Epub 2009 Feb 26.PMID: 19246535 [PubMed - indexed for MEDLINE]Related articles

Low aerobic capacity and high-fat diet contribute to oxidative stress and IRS-1 degradation in the kidney.

Morris EM, Whaley-Connell AT, Thyfault JP, Britton SL, Koch LG, Wei Y, Ibdah JA, Sowers JR.

Am J Nephrol. 2009;30(2):112-9. Epub 2009 Feb 20.PMID: 19229113 [PubMed - indexed for MEDLINE]Related articles

Differential regulation of angiotensin-(1-12) in plasma and cardiac tissue in response to bilateral nephrectomy.

Ferrario CM, Varagic J, Habibi J, Nagata S, Kato J, Chappell MC, Trask AJ, Kitamura K, Whaley-Connell A, Sowers JR.

Am J Physiol Heart Circ Physiol. 2009 Apr;296(4):H1184-92. Epub 2009 Feb 13.PMID: 19218503 [PubMed - indexed for MEDLINE]Related articles

Renin-angiotensin-aldosterone system-mediated redox effects in chronic kidney disease.

Nistala R, Wei Y, Sowers JR, Whaley-Connell A.

Transl Res. 2009 Mar;153(3):102-13. Epub 2009 Jan 23. Review.PMID: 19218092 [PubMed - indexed for MEDLINE]Related articles

Role of aldosterone and angiotensin II in insulin resistance: an update.

Lastra-Lastra G, Sowers JR, Restrepo-Erazo K, Manrique-Acevedo C, Lastra-González G.

Clin Endocrinol (Oxf). 2009 Jul;71(1):1-6. Epub 2008 Dec 5. Review.PMID: 19138313 [PubMed - indexed for MEDLINE]Related articles

Progress and controversies: treating obesity and insulin resistance in the context of hypertension.

McGill JB, Haffner S, Rees TJ, Sowers JR, Tershakovec AM, Weber M.

J Clin Hypertens (Greenwich). 2009 Jan;11(1):36-41. Review.PMID: 19125857 [PubMed - indexed for MEDLINE]Related articles

Aspirin and Diabetes Mellitus: revisiting an old player.

Manrique C, Lastra G, Palmer J, Gardner M, Sowers JR.

Ther Adv Cardiovasc Dis. 2008 Feb;2(1):37-42. Review.PMID: 19124406 [PubMed - indexed for MEDLINE]Related articles

Therapy for the altered mineral metabolism of chronic kidney disease: implications for vascular calcification.

Saab G, Whaley-Connell AT, Khanna R, Sowers JR.

Ther Adv Cardiovasc Dis. 2007 Dec;1(2):107-12. Review.PMID: 19124399 [PubMed - indexed for MEDLINE]Related articles

Metabolic and antihypertensive effects of combined angiotensin receptor blocker and diuretic therapy in prediabetic hypertensive patients with the cardiometabolic syndrome.

Zappe DH, Sowers JR, Hsueh WA, Haffner SM, Deedwania PC, Fonseca VA, Keeling L, Sica DA.

J Clin Hypertens (Greenwich). 2008 Dec;10(12):894-903.PMID: 19120715 [PubMed - indexed for MEDLINE]Related articles

Mineralocorticoid receptor antagonism attenuates vascular apoptosis and injury via rescuing protein kinase B activation.

Wei Y, Whaley-Connell AT, Habibi J, Rehmer J, Rehmer N, Patel K, Hayden M, DeMarco V, Ferrario CM, Ibdah JA, Sowers JR.

Hypertension. 2009 Feb;53(2):158-65. Epub 2008 Dec 29.PMID: 19114643 [PubMed - indexed for MEDLINE]Related articles

Exercise training prevents development of cardiac contractile dysfunction in hypertensive TG (mREN-2)27 rats.

Morris RT, Fine DM, Lees SJ, Booth FW, Link CD, Ferrario CM, Stump CS, Sowers JR.

J Am Soc Hypertens. 2007 Dec;1(6):393-399.PMID: 19050745 [PubMed]Related articlesFree article

Endocrine functions of adipose tissue: focus on adiponectin.

Sowers JR.

Clin Cornerstone. 2008;9(1):32-8; discussion 39-40. Review.PMID: 19046738 [PubMed - indexed for MEDLINE]Related articles

Surgical treatment of the cardiometabolic syndrome and obesity.

Khan KA, Sowers JR.

J Cardiometab Syndr. 2008 Fall;3(4):254-7. Review.PMID: 19040595 [PubMed - indexed for MEDLINE]Related articles

Attenuation of endocrine-exocrine pancreatic communication in type 2 diabetes: pancreatic extracellular matrix ultrastructural abnormalities.

Hayden MR, Patel K, Habibi J, Gupta D, Tekwani SS, Whaley-Connell A, Sowers JR.

J Cardiometab Syndr. 2008 Fall;3(4):234-43. Review.PMID: 19040593 [PubMed - indexed for MEDLINE]Related articlesFree article

Pancreatic renin-angiotensin-aldosterone system in the cardiometabolic syndrome and type 2 diabetes mellitus.

Hayden MR, Sowers JR.

J Cardiometab Syndr. 2008 Summer;3(3):129-31. No abstract available. PMID: 18983326 [PubMed - indexed for MEDLINE]Related articles

The cardiometabolic syndrome in the adolescent.

Gardner M, Gardner DW, Sowers JR.

Pediatr Endocrinol Rev. 2008 Aug;5 Suppl 4:964-8. Review.PMID: 18806711 [PubMed - indexed for MEDLINE]Related articles

ASH position paper: treatment of hypertension in patients with diabetes-an update.

Bakris GL, Sowers JR; American Society of Hypertension Writing Group.

J Clin Hypertens (Greenwich). 2008 Sep;10(9):707-13; discussion 714-5.PMID: 18844766 [PubMed - indexed for MEDLINE]Related articles

Initial combination therapy compared with monotherapy in diabetic hypertensive patients.

Sowers JR, Lastra G, Rocha R, Seifu Y, Crikelair N, Levy DG.

J Clin Hypertens (Greenwich). 2008 Sep;10(9):668-76.PMID: 18844761 [PubMed - indexed for MEDLINE]Related articles

Redox control of renal function and hypertension.

Nistala R, Whaley-Connell A, Sowers JR.

Antioxid Redox Signal. 2008 Dec;10(12):2047-89. Review.PMID: 18821850 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypertension in obesity.

Kurukulasuriya LR, Stas S, Lastra G, Manrique C, Sowers JR.

Endocrinol Metab Clin North Am. 2008 Sep;37(3):647-62, ix. Review.PMID: 18775357 [PubMed - indexed for MEDLINE]Related articles

Renin inhibition attenuates insulin resistance, oxidative stress, and pancreatic remodeling in the transgenic Ren2 rat.

Habibi J, Whaley-Connell A, Hayden MR, DeMarco VG, Schneider R, Sowers SD, Karuparthi P, Ferrario CM, Sowers JR.

Endocrinology. 2008 Nov;149(11):5643-53. Epub 2008 Jul 24.PMID: 18653711 [PubMed - indexed for MEDLINE]Related articlesFree article

Ultrastructure of islet microcirculation, pericytes and the islet exocrine interface in the HIP rat model of diabetes.

Hayden MR, Karuparthi PR, Habibi J, Lastra G, Patel K, Wasekar C, Manrique CM, Ozerdem U, Stas S, Sowers JR.

Exp Biol Med (Maywood). 2008 Sep;233(9):1109-23. Epub 2008 Jul 18.PMID: 18641056 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin resistance and blood pressure.

Addison S, Stas S, Hayden MR, Sowers JR.

Curr Hypertens Rep. 2008 Aug;10(4):319-25. Review.PMID: 18625163 [PubMed - indexed for MEDLINE]Related articles

The role of aldosterone in cardiovascular disease in people with diabetes and hypertension: an update.

Lastra-Gonzalez G, Manrique-Acevedo C, Sowers JR.

Curr Diab Rep. 2008 Jun;8(3):203-7. Review.PMID: 18625117 [PubMed - indexed for MEDLINE]Related articles

Risk factor assessment for new onset diabetes: literature review.

Bakris G, Stockert J, Molitch M, Zhou Q, Champion A, Bacher P, Sowers J; STAR Investigators.

Diabetes Obes Metab. 2009 Mar;11(3):177-87. Epub 2008 Jun 16. Review.PMID: 18564174 [PubMed - indexed for MEDLINE]Related articles

Angiotensin II-induced non-alcoholic fatty liver disease is mediated by oxidative stress in transgenic TG(mRen2)27(Ren2) rats.

Wei Y, Clark SE, Morris EM, Thyfault JP, Uptergrove GM, Whaley-Connell AT, Ferrario CM, Sowers JR, Ibdah JA.

J Hepatol. 2008 Sep;49(3):417-28. Epub 2008 Apr 22.PMID: 18486983 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of renin inhibition and AT1R blockade on myocardial remodeling in the transgenic Ren2 rat.

Whaley-Connell A, Habibi J, Cooper SA, Demarco VG, Hayden MR, Stump CS, Link D, Ferrario CM, Sowers JR.

Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E103-9. Epub 2008 May 6.PMID: 18460596 [PubMed - indexed for MEDLINE]Related articlesFree article

Low-dose spironolactone reduces reactive oxygen species generation and improves insulin-stimulated glucose transport in skeletal muscle in the TG(mRen2)27 rat.

Lastra G, Whaley-Connell A, Manrique C, Habibi J, Gutweiler AA, Appesh L, Hayden MR, Wei Y, Ferrario C, Sowers JR.

Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E110-6. Epub 2008 Apr 29.PMID: 18445755 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress contributes to pulmonary hypertension in the transgenic (mRen2)27 rat.

DeMarco VG, Habibi J, Whaley-Connell AT, Schneider RI, Heller RL, Bosanquet JP, Hayden MR, Delcour K, Cooper SA, Andresen BT, Sowers JR, Dellsperger KC.

Am J Physiol Heart Circ Physiol. 2008 Jun;294(6):H2659-68. Epub 2008 Apr 18.PMID: 18424632 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevalence and associations of anemia of CKD: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES) 1999-2004.

McFarlane SI, Chen SC, Whaley-Connell AT, Sowers JR, Vassalotti JA, Salifu MO, Li S, Wang C, Bakris G, McCullough PA, Collins AJ, Norris KC; Kidney Early Evaluation Program Investigators.

Am J Kidney Dis. 2008 Apr;51(4 Suppl 2):S46-55.PMID: 18359408 [PubMed - indexed for MEDLINE]Related articles

Diabetes mellitus in CKD: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition and Examination Survey (NHANES) 1999-2004.

Whaley-Connell AT, Sowers JR, McFarlane SI, Norris KC, Chen SC, Li S, Qiu Y, Wang C, Stevens LA, Vassalotti JA, Collins AJ; Kidney Early Evaluation Program Investigators.

Am J Kidney Dis. 2008 Apr;51(4 Suppl 2):S21-9.PMID: 18359404 [PubMed - indexed for MEDLINE]Related articles

CKD in the United States: Kidney Early Evaluation Program (KEEP) and National Health and Nutrition Examination Survey (NHANES) 1999-2004.

Whaley-Connell AT, Sowers JR, Stevens LA, McFarlane SI, Shlipak MG, Norris KC, Chen SC, Qiu Y, Wang C, Li S, Vassalotti JA, Collins AJ; Kidney Early Evaluation Program Investigators.

Am J Kidney Dis. 2008 Apr;51(4 Suppl 2):S13-20.PMID: 18359403 [PubMed - indexed for MEDLINE]Related articles