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    Results: 20

    1.

    Synthesis and SAR of 1,2,3,4-tetrahydroisoquinolin-1-ones as novel G-protein-coupled receptor 40 (GPR40) antagonists.

    Humphries PS, Benbow JW, Bonin PD, Boyer D, Doran SD, Frisbie RK, Piotrowski DW, Balan G, Bechle BM, Conn EL, Dirico KJ, Oliver RM, Soeller WC, Southers JA, Yang X.

    Bioorg Med Chem Lett. 2009 May 1;19(9):2400-3. Epub 2009 Mar 25.PMID: 19346127 [PubMed - indexed for MEDLINE]Related articles

    2.

    Induction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide.

    Huang CJ, Haataja L, Gurlo T, Butler AE, Wu X, Soeller WC, Butler PC.

    Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1656-62. Epub 2007 Oct 2.PMID: 17911343 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    (3R,4S)-4-(2,4,5-Trifluorophenyl)-pyrrolidin-3-ylamine inhibitors of dipeptidyl peptidase IV: synthesis, in vitro, in vivo, and X-ray crystallographic characterization.

    Wright SW, Ammirati MJ, Andrews KM, Brodeur AM, Danley DE, Doran SD, Lillquist JS, Liu S, McClure LD, McPherson RK, Olson TV, Orena SJ, Parker JC, Rocke BN, Soeller WC, Soglia CB, Treadway JL, Vanvolkenburg MA, Zhao Z, Cox ED.

    Bioorg Med Chem Lett. 2007 Oct 15;17(20):5638-42. Epub 2007 Aug 22.PMID: 17822893 [PubMed - indexed for MEDLINE]Related articles

    4.

    cis-2,5-dicyanopyrrolidine inhibitors of dipeptidyl peptidase IV: synthesis and in vitro, in vivo, and X-ray crystallographic characterization.

    Wright SW, Ammirati MJ, Andrews KM, Brodeur AM, Danley DE, Doran SD, Lillquist JS, McClure LD, McPherson RK, Orena SJ, Parker JC, Polivkova J, Qiu X, Soeller WC, Soglia CB, Treadway JL, VanVolkenburg MA, Wang H, Wilder DC, Olson TV.

    J Med Chem. 2006 Jun 1;49(11):3068-76.PMID: 16722626 [PubMed - indexed for MEDLINE]Related articles

    5.

    The sulfonylurea glipizide does not inhibit ischemic preconditioning in anesthetized rabbits.

    Flynn DM, Smith AH, Treadway JL, Levy CB, Soeller WC, Boettner WA, Wisniecki P, Plowchalk DR, Gernhardt SS, Tracey WR, Knight DR.

    Cardiovasc Drugs Ther. 2005 Oct;19(5):337-46.PMID: 16382296 [PubMed - indexed for MEDLINE]Related articles

    6.

    Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes.

    Butler AE, Jang J, Gurlo T, Carty MD, Soeller WC, Butler PC.

    Diabetes. 2004 Jun;53(6):1509-16.PMID: 15161755 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid.

    Butler AE, Janson J, Soeller WC, Butler PC.

    Diabetes. 2003 Sep;52(9):2304-14.PMID: 12941770 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase.

    Ekstrom JL, Pauly TA, Carty MD, Soeller WC, Culp J, Danley DE, Hoover DJ, Treadway JL, Gibbs EM, Fletterick RJ, Day YS, Myszka DG, Rath VL.

    Chem Biol. 2002 Aug;9(8):915-24.PMID: 12204691 [PubMed - indexed for MEDLINE]Related articles

    9.

    Anilinoquinazoline inhibitors of fructose 1,6-bisphosphatase bind at a novel allosteric site: synthesis, in vitro characterization, and X-ray crystallography.

    Wright SW, Carlo AA, Carty MD, Danley DE, Hageman DL, Karam GA, Levy CB, Mansour MN, Mathiowetz AM, McClure LD, Nestor NB, McPherson RK, Pandit J, Pustilnik LR, Schulte GK, Soeller WC, Treadway JL, Wang IK, Bauer PH.

    J Med Chem. 2002 Aug 29;45(18):3865-77.PMID: 12190310 [PubMed - indexed for MEDLINE]Related articles

    10.

    Estrogen can prevent or reverse obesity and diabetes in mice expressing human islet amyloid polypeptide.

    Geisler JG, Zawalich W, Zawalich K, Lakey JR, Stukenbrok H, Milici AJ, Soeller WC.

    Diabetes. 2002 Jul;51(7):2158-69.PMID: 12086946 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Identification of a novel glucose transporter-like protein-GLUT-12.

    Rogers S, Macheda ML, Docherty SE, Carty MD, Henderson MA, Soeller WC, Gibbs EM, James DE, Best JD.

    Am J Physiol Endocrinol Metab. 2002 Mar;282(3):E733-8.PMID: 11832379 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Islet amyloid-associated diabetes in obese A(vy)/a mice expressing human islet amyloid polypeptide.

    Soeller WC, Janson J, Hart SE, Parker JC, Carty MD, Stevenson RW, Kreutter DK, Butler PC.

    Diabetes. 1998 May;47(5):743-50.PMID: 9588445 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells.

    Carty MD, Lillquist JS, Peshavaria M, Stein R, Soeller WC.

    J Biol Chem. 1997 May 2;272(18):11986-93.PMID: 9115263 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide.

    Janson J, Soeller WC, Roche PC, Nelson RT, Torchia AJ, Kreutter DK, Butler PC.

    Proc Natl Acad Sci U S A. 1996 Jul 9;93(14):7283-8.PMID: 8692984 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Isolation of cDNAs encoding the Drosophila GAGA transcription factor.

    Soeller WC, Oh CE, Kornberg TB.

    Mol Cell Biol. 1993 Dec;13(12):7961-70.PMID: 7504178 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Germline manipulation of glucose homeostasis via alteration of glucose transporter levels in skeletal muscle.

    Marshall BA, Ren JM, Johnson DW, Gibbs EM, Lillquist JS, Soeller WC, Holloszy JO, Mueckler M.

    J Biol Chem. 1993 Sep 5;268(25):18442-5.PMID: 8360145 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    In vitro transcription of the Drosophila engrailed gene.

    Soeller WC, Poole SJ, Kornberg T.

    Genes Dev. 1988 Jan;2(1):68-81.PMID: 3356339 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    The transcription unit of the Drosophila engrailed locus: an unusually small portion of a 70,000 bp gene.

    Drees B, Ali Z, Soeller WC, Coleman KG, Poole SJ, Kornberg T.

    EMBO J. 1987 Sep;6(9):2803-9.PMID: 2445563 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    The invected gene of Drosophila: sequence analysis and expression studies reveal a close kinship to the engrailed gene.

    Coleman KG, Poole SJ, Weir MP, Soeller WC, Kornberg T.

    Genes Dev. 1987 Mar;1(1):19-28.PMID: 2892756 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Deletion mutants defining the Escherichia coli replication factor Y effector site sequences in pBR322 DNA.

    Soeller WC, Marians KJ.

    Proc Natl Acad Sci U S A. 1982 Dec;79(23):7253-7.PMID: 6130524 [PubMed - indexed for MEDLINE]Related articlesFree article

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