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A Novel G-Quadruplex Binding Protein in Yeast-Slx9.
Götz S, Pandey S, Bartsch S, Juranek S, Paeschke K. Götz S, et al. Molecules. 2019 May 7;24(9):1774. doi: 10.3390/molecules24091774. Molecules. 2019. PMID: 31067825 Free PMC article.
Considering the high thermodynamic stability of G4 structures, various proteins are necessary for G4 structure formation and unwinding. In a yeast one-hybrid screen, we identified Slx9 as a novel G4-binding protein. We confirmed that Slx9 binds to G4 DNA structures …
Considering the high thermodynamic stability of G4 structures, various proteins are necessary for G4 structure formation and unwinding. In a …
A non-canonical mechanism for Crm1-export cargo complex assembly.
Fischer U, Schäuble N, Schütz S, Altvater M, Chang Y, Faza MB, Panse VG. Fischer U, et al. Elife. 2015 Apr 21;4:e05745. doi: 10.7554/eLife.05745. Elife. 2015. PMID: 25895666 Free PMC article.
A mutation in Slx9 that impairs Crm1-export complex assembly inhibits 40S pre-ribosome export. Thus, Slx9 functions as a scaffold to optimally present RanGTP and the NES to Crm1, therefore, triggering 40S pre-ribosome export. ...
A mutation in Slx9 that impairs Crm1-export complex assembly inhibits 40S pre-ribosome export. Thus, Slx9 functions as a scaff …
The nucleoplasmic phase of pre-40S formation prior to nuclear export.
Cheng J, Lau B, Thoms M, Ameismeier M, Berninghausen O, Hurt E, Beckmann R. Cheng J, et al. Nucleic Acids Res. 2022 Nov 11;50(20):11924-11937. doi: 10.1093/nar/gkac961. Nucleic Acids Res. 2022. PMID: 36321656 Free PMC article.
Eventually, the uS2 cluster, CK1 (Hrr25 in yeast) and the export factor SLX9 associate with the pre-40S to provide export competence. These exemplary findings reveal the evolutionary conserved mechanism of how yeast and humans assemble the 40S ribosomal subunit, but reveal …
Eventually, the uS2 cluster, CK1 (Hrr25 in yeast) and the export factor SLX9 associate with the pre-40S to provide export competence. …
Slx9p facilitates efficient ITS1 processing of pre-rRNA in Saccharomyces cerevisiae.
Bax R, Raué HA, Vos JC. Bax R, et al. RNA. 2006 Nov;12(11):2005-13. doi: 10.1261/rna.159406. Epub 2006 Oct 3. RNA. 2006. PMID: 17018574 Free PMC article.
The most striking effects on pre-rRNA processing resulting from deletion of SLX9 is the accumulation of the mutually exclusive 21S and 27SA2 pre-rRNA. Furthermore, deletion of SLX9 is synthetically lethal with mutations in Rrp5p that block cleavage at either site A2 …
The most striking effects on pre-rRNA processing resulting from deletion of SLX9 is the accumulation of the mutually exclusive 21S an …
A new plant sex-linked gene with high sequence diversity and possible introgression of the X copy.
Kaiser VB, Bergero R, Charlesworth D. Kaiser VB, et al. Heredity (Edinb). 2011 Feb;106(2):339-47. doi: 10.1038/hdy.2010.76. Epub 2010 Jun 16. Heredity (Edinb). 2011. PMID: 20551975 Free PMC article.
We describe patterns of DNA sequence diversity in a newly identified sex-linked gene, SlX9/SlY9, in Silene latifolia (Caryophyllaceae). The copies on both sex chromosomes seem to be functional, and each maps close to the respective X- and Y-linked copy of another sex-linke …
We describe patterns of DNA sequence diversity in a newly identified sex-linked gene, SlX9/SlY9, in Silene latifolia (Caryophyllaceae …
Impact of two neighbouring ribosomal protein clusters on biogenesis factor binding and assembly of yeast late small ribosomal subunit precursors.
Linnemann J, Pöll G, Jakob S, Ferreira-Cerca S, Griesenbeck J, Tschochner H, Milkereit P. Linnemann J, et al. PLoS One. 2019 Jan 17;14(1):e0203415. doi: 10.1371/journal.pone.0203415. eCollection 2019. PLoS One. 2019. PMID: 30653518 Free PMC article.
These suggested a role of S0-cluster formation for the efficient release of the two nuclear export factors Rrp12 and Slx9 from SSU precursors and for the correct incorporation of the late acting biogenesis factor Rio2. ...
These suggested a role of S0-cluster formation for the efficient release of the two nuclear export factors Rrp12 and Slx9 from SSU pr …