PubMed

Analysis of knockout mice suggests a role for VGF in the control of fat storage and energy expenditure.

Watson E, Fargali S, Okamoto H, Sadahiro M, Gordon RE, Chakraborty T, Sleeman MW, Salton SR.

BMC Physiol. 2009 Oct 28;9:19.PMID: 19863797 [PubMed - in process]Related articlesFree article

Reduced anticipatory locomotor responses to scheduled meals in ghrelin receptor deficient mice.

Blum ID, Patterson Z, Khazall R, Lamont EW, Sleeman MW, Horvath TL, Abizaid A.

Neuroscience. 2009 Dec 1;164(2):351-9. Epub 2009 Aug 8.PMID: 19666088 [PubMed - in process]Related articles

Increased fear- and stress-related anxiety-like behavior in mice lacking tuberoinfundibular peptide of 39 residues.

Fegley DB, Holmes A, Riordan T, Faber CA, Weiss JR, Ma S, Batkai S, Pacher P, Dobolyi A, Murphy A, Sleeman MW, Usdin TB.

Genes Brain Behav. 2008 Nov;7(8):933-42. Epub 2008 Sep 17.PMID: 18700839 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.

López M, Lage R, Saha AK, Pérez-Tilve D, Vázquez MJ, Varela L, Sangiao-Alvarellos S, Tovar S, Raghay K, Rodríguez-Cuenca S, Deoliveira RM, Castañeda T, Datta R, Dong JZ, Culler M, Sleeman MW, Alvarez CV, Gallego R, Lelliott CJ, Carling D, Tschöp MH, Diéguez C, Vidal-Puig A.

Cell Metab. 2008 May;7(5):389-99.PMID: 18460330 [PubMed - indexed for MEDLINE]Related articles

The CAMplexities of central ghrelin.

Sleeman MW, Latres E.

Cell Metab. 2008 May;7(5):361-2.PMID: 18460326 [PubMed - indexed for MEDLINE]Related articles

The mutation ROR2W749X, linked to human BDB, is a recessive mutation in the mouse, causing brachydactyly, mediating patterning of joints and modeling recessive Robinow syndrome.

Raz R, Stricker S, Gazzerro E, Clor JL, Witte F, Nistala H, Zabski S, Pereira RC, Stadmeyer L, Wang X, Gowen L, Sleeman MW, Yancopoulos GD, Canalis E, Mundlos S, Valenzuela DM, Economides AN.

Development. 2008 May;135(9):1713-23. Epub 2008 Mar 19.PMID: 18353862 [PubMed - indexed for MEDLINE]Related articlesFree article

Simultaneous deletion of ghrelin and its receptor increases motor activity and energy expenditure.

Pfluger PT, Kirchner H, Günnel S, Schrott B, Perez-Tilve D, Fu S, Benoit SC, Horvath T, Joost HG, Wortley KE, Sleeman MW, Tschöp MH.

Am J Physiol Gastrointest Liver Physiol. 2008 Mar;294(3):G610-8. Epub 2007 Nov 29.PMID: 18048479 [PubMed - indexed for MEDLINE]Related articlesFree article

Peptide YY regulates bone turnover in rodents.

Wortley KE, Garcia K, Okamoto H, Thabet K, Anderson KD, Shen V, Herman JP, Valenzuela D, Yancopoulos GD, Tschöp MH, Murphy A, Sleeman MW.

Gastroenterology. 2007 Nov;133(5):1534-43. Epub 2007 Aug 15.PMID: 17920065 [PubMed - indexed for MEDLINE]Related articles

Mice genetically deficient in neuromedin U receptor 2, but not neuromedin U receptor 1, have impaired nociceptive responses.

Torres R, Croll SD, Vercollone J, Reinhardt J, Griffiths J, Zabski S, Anderson KD, Adams NC, Gowen L, Sleeman MW, Valenzuela DM, Wiegand SJ, Yancopoulos GD, Murphy AJ.

Pain. 2007 Aug;130(3):267-78. Epub 2007 Mar 26.PMID: 17379411 [PubMed - indexed for MEDLINE]Related articles

Genetic deletion of Trb3, the mammalian Drosophila tribbles homolog, displays normal hepatic insulin signaling and glucose homeostasis.

Okamoto H, Latres E, Liu R, Thabet K, Murphy A, Valenzeula D, Yancopoulos GD, Stitt TN, Glass DJ, Sleeman MW.

Diabetes. 2007 May;56(5):1350-6. Epub 2007 Feb 15.PMID: 17303803 [PubMed - indexed for MEDLINE]Related articlesFree article

Decreased hepatic futile cycling compensates for increased glucose disposal in the Pten heterodeficient mouse.

Xu J, Gowen L, Raphalides C, Hoyer KK, Weinger JG, Renard M, Troke JJ, Vaitheesyaran B, Lee WN, Saad MF, Sleeman MW, Teitell MA, Kurland IJ.

Diabetes. 2006 Dec;55(12):3372-80.PMID: 17130482 [PubMed - indexed for MEDLINE]Related articlesFree article

Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite.

Abizaid A, Liu ZW, Andrews ZB, Shanabrough M, Borok E, Elsworth JD, Roth RH, Sleeman MW, Picciotto MR, Tschöp MH, Gao XB, Horvath TL.

J Clin Invest. 2006 Dec;116(12):3229-39. Epub 2006 Oct 19.PMID: 17060947 [PubMed - indexed for MEDLINE]Related articlesFree article

Ghrelin controls hippocampal spine synapse density and memory performance.

Diano S, Farr SA, Benoit SC, McNay EC, da Silva I, Horvath B, Gaskin FS, Nonaka N, Jaeger LB, Banks WA, Morley JE, Pinto S, Sherwin RS, Xu L, Yamada KA, Sleeman MW, Tschöp MH, Horvath TL.

Nat Neurosci. 2006 Mar;9(3):381-8. Epub 2006 Feb 19.PMID: 16491079 [PubMed - indexed for MEDLINE]Related articles

Agouti-related protein-deficient mice display an age-related lean phenotype.

Wortley KE, Anderson KD, Yasenchak J, Murphy A, Valenzuela D, Diano S, Yancopoulos GD, Wiegand SJ, Sleeman MW.

Cell Metab. 2005 Dec;2(6):421-7.PMID: 16330327 [PubMed - indexed for MEDLINE]Related articles

Absence of ghrelin protects against early-onset obesity.

Wortley KE, del Rincon JP, Murray JD, Garcia K, Iida K, Thorner MO, Sleeman MW.

J Clin Invest. 2005 Dec;115(12):3573-8.PMID: 16322795 [PubMed - indexed for MEDLINE]Related articlesFree article

Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity.

Harvey NL, Srinivasan RS, Dillard ME, Johnson NC, Witte MH, Boyd K, Sleeman MW, Oliver G.

Nat Genet. 2005 Oct;37(10):1072-81. Epub 2005 Sep 18.PMID: 16170315 [PubMed - indexed for MEDLINE]Related articles

Resistance to diet-induced obesity in mice globally overexpressing OGH/GPB5.

Macdonald LE, Wortley KE, Gowen LC, Anderson KD, Murray JD, Poueymirou WT, Simmons MV, Barber D, Valenzuela DM, Economides AN, Wiegand SJ, Yancopoulos GD, Sleeman MW, Murphy AJ.

Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2496-501. Epub 2005 Feb 7.PMID: 15699348 [PubMed - indexed for MEDLINE]Related articlesFree article

Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity.

Sleeman MW, Wortley KE, Lai KM, Gowen LC, Kintner J, Kline WO, Garcia K, Stitt TN, Yancopoulos GD, Wiegand SJ, Glass DJ.

Nat Med. 2005 Feb;11(2):199-205. Epub 2005 Jan 16. Erratum in: Nat Med. 2005 Mar;11(3):353. PMID: 15654325 [PubMed - indexed for MEDLINE]Related articles

Ciliary neurotrophic factorAx15 alters energy homeostasis, decreases body weight, and improves metabolic control in diet-induced obese and UCP1-DTA mice.

Blüher S, Moschos S, Bullen J Jr, Kokkotou E, Maratos-Flier E, Wiegand SJ, Sleeman MW, Mantzoros CS.

Diabetes. 2004 Nov;53(11):2787-96. Erratum in: Diabetes. 2005 Jan;54(1):296. Sleemann, Mark W [corrected to Sleeman, Mark W]. PMID: 15504958 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic deletion of ghrelin does not decrease food intake but influences metabolic fuel preference.

Wortley KE, Anderson KD, Garcia K, Murray JD, Malinova L, Liu R, Moncrieffe M, Thabet K, Cox HJ, Yancopoulos GD, Wiegand SJ, Sleeman MW.

Proc Natl Acad Sci U S A. 2004 May 25;101(21):8227-32. Epub 2004 May 17.PMID: 15148384 [PubMed - indexed for MEDLINE]Related articlesFree article

Ciliary neurotrophic factor improves diabetic parameters and hepatic steatosis and increases basal metabolic rate in db/db mice.

Sleeman MW, Garcia K, Liu R, Murray JD, Malinova L, Moncrieffe M, Yancopoulos GD, Wiegand SJ.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14297-302. Epub 2003 Nov 10.PMID: 14610276 [PubMed - indexed for MEDLINE]Related articlesFree article

Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity.

Lambert PD, Anderson KD, Sleeman MW, Wong V, Tan J, Hijarunguru A, Corcoran TL, Murray JD, Thabet KE, Yancopoulos GD, Wiegand SJ.

Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4652-7. Epub 2001 Mar 20.PMID: 11259650 [PubMed - indexed for MEDLINE]Related articlesFree article

The ciliary neurotrophic factor and its receptor, CNTFR alpha.

Sleeman MW, Anderson KD, Lambert PD, Yancopoulos GD, Wiegand SJ.

Pharm Acta Helv. 2000 Mar;74(2-3):265-72. Review.PMID: 10812968 [PubMed - indexed for MEDLINE]Related articles

Association of acyl-CoA synthetase-1 with GLUT4-containing vesicles.

Sleeman MW, Donegan NP, Heller-Harrison R, Lane WS, Czech MP.

J Biol Chem. 1998 Feb 6;273(6):3132-5.PMID: 9452420 [PubMed - indexed for MEDLINE]Related articlesFree article

Modulation of glucose transport by parathyroid hormone and insulin in UMR 106-01, a clonal rat osteogenic sarcoma cell line.

Thomas DM, Rogers SD, Sleeman MW, Pasquini GM, Bringhurst FR, Ng KW, Zajac JD, Best JD.

J Mol Endocrinol. 1995 Apr;14(2):263-75.PMID: 7619214 [PubMed - indexed for MEDLINE]Related articles

Retinoic acid stimulates glucose transporter expression in L6 muscle cells.

Sleeman MW, Zhou H, Rogers S, Ng KW, Best JD.

Mol Cell Endocrinol. 1995 Feb 27;108(1-2):161-7.PMID: 7758830 [PubMed - indexed for MEDLINE]Related articles

Effects of acute and chronic counterregulatory hormone infusions on glucose tolerance and insulin sensitivity in diabetic dogs.

Sleeman MW, Christopher MJ, Martin IK, Ward GM, Alford FP, Best JD.

Diabetes. 1992 Nov;41(11):1446-52.PMID: 1397720 [PubMed - indexed for MEDLINE]Related articles

Contrasting action of short- and long-term adrenaline infusion on dog skeletal muscle glucose metabolism.

Christopher MJ, Sleeman MW, Alford FP, Best JD.

Diabetologia. 1992 May;35(5):399-405.PMID: 1387857 [PubMed - indexed for MEDLINE]Related articles