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Epigenetic mechanisms in the development of type 2 diabetes.

Pinney SE, Simmons RA.

Trends Endocrinol Metab. 2009 Oct 26. [Epub ahead of print]PMID: 19864158 [PubMed - as supplied by publisher]Related articles

Neonatal Exendin-4 Treatment Reduces Oxidative Stress and Prevents Hepatic Insulin Resistance in Intrauterine Growth Retarded Rats.

Raab EL, Vuguin PM, Stoffers DA, Simmons RA.

Am J Physiol Regul Integr Comp Physiol. 2009 Oct 21. [Epub ahead of print]PMID: 19846744 [PubMed - as supplied by publisher]Related articles

Developmental origins of adult disease.

Simmons RA.

Pediatr Clin North Am. 2009 Jun;56(3):449-66, Table of Contents. Review.PMID: 19501686 [PubMed - indexed for MEDLINE]Related articles

Oxidative stress disrupts oligodendrocyte maturation.

French HM, Reid M, Mamontov P, Simmons RA, Grinspan JB.

J Neurosci Res. 2009 Nov 1;87(14):3076-87.PMID: 19479983 [PubMed - indexed for MEDLINE]Related articles

Exendin-4 normalizes islet vascularity in intrauterine growth restricted rats: potential role of VEGF.

Ham JN, Crutchlow MF, Desai BM, Simmons RA, Stoffers DA.

Pediatr Res. 2009 Jul;66(1):42-6.PMID: 19287346 [PubMed - indexed for MEDLINE]Related articles

How do hostile and emotionally overinvolved relatives view relationships? What relatives' pronoun use tells us.

Simmons RA, Chambless DL, Gordon PC.

Fam Process. 2008 Sep;47(3):405-19.PMID: 18831315 [PubMed - indexed for MEDLINE]Related articles

Molecular mechanisms for hyperinsulinaemia induced by overproduction of selenium-dependent glutathione peroxidase-1 in mice.

Wang XD, Vatamaniuk MZ, Wang SK, Roneker CA, Simmons RA, Lei XG.

Diabetologia. 2008 Aug;51(8):1515-24. Epub 2008 Jun 17.PMID: 18560803 [PubMed - indexed for MEDLINE]Related articles

Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1.

Park JH, Stoffers DA, Nicholls RD, Simmons RA.

J Clin Invest. 2008 Jun;118(6):2316-24.PMID: 18464933 [PubMed - indexed for MEDLINE]Related articlesFree article

Developmental origins of diabetes: the role of epigenetic mechanisms.

Simmons RA.

Curr Opin Endocrinol Diabetes Obes. 2007 Feb;14(1):13-6. Review.PMID: 17940413 [PubMed - indexed for MEDLINE]Related articles

Role of metabolic programming in the pathogenesis of beta-cell failure in postnatal life.

Simmons RA.

Rev Endocr Metab Disord. 2007 Jun;8(2):95-104. Review.PMID: 17680370 [PubMed - indexed for MEDLINE]Related articles

Developmental origins of beta-cell failure in type 2 diabetes: the role of epigenetic mechanisms.

Simmons RA.

Pediatr Res. 2007 May;61(5 Pt 2):64R-67R. Review.PMID: 17413845 [PubMed - indexed for MEDLINE]Related articles

Developmental origins of diabetes: the role of oxidative stress.

Simmons RA.

Free Radic Biol Med. 2006 Mar 15;40(6):917-22. Epub 2006 Jan 13. Review.PMID: 16540386 [PubMed - indexed for MEDLINE]Related articles

Clinical features and insulin regulation in infants with a syndrome of prolonged neonatal hyperinsulinism.

Hoe FM, Thornton PS, Wanner LA, Steinkrauss L, Simmons RA, Stanley CA.

J Pediatr. 2006 Feb;148(2):207-12.PMID: 16492430 [PubMed - indexed for MEDLINE]Related articles

Pronouns in marital interaction.

Simmons RA, Gordon PC, Chambless DL.

Psychol Sci. 2005 Dec;16(12):932-6.PMID: 16313655 [PubMed - indexed for MEDLINE]Related articles

Hormonal and metabolic defects in a prader-willi syndrome mouse model with neonatal failure to thrive.

Stefan M, Ji H, Simmons RA, Cummings DE, Ahima RS, Friedman MI, Nicholls RD.

Endocrinology. 2005 Oct;146(10):4377-85. Epub 2005 Jul 7.PMID: 16002520 [PubMed - indexed for MEDLINE]Related articlesFree article

Progressive accumulation of mitochondrial DNA mutations and decline in mitochondrial function lead to beta-cell failure.

Simmons RA, Suponitsky-Kroyter I, Selak MA.

J Biol Chem. 2005 Aug 5;280(31):28785-91. Epub 2005 Jun 9.PMID: 15946949 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired oxidative phosphorylation in hepatic mitochondria in growth-retarded rats.

Peterside IE, Selak MA, Simmons RA.

Am J Physiol Endocrinol Metab. 2003 Dec;285(6):E1258-66.PMID: 14607783 [PubMed - indexed for MEDLINE]Related articlesFree article

Mice deficient for testis-brain RNA-binding protein exhibit a coordinate loss of TRAX, reduced fertility, altered gene expression in the brain, and behavioral changes.

Chennathukuzhi V, Stein JM, Abel T, Donlon S, Yang S, Miller JP, Allman DM, Simmons RA, Hecht NB.

Mol Cell Biol. 2003 Sep;23(18):6419-34.PMID: 12944470 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired oxidative phosphorylation in skeletal muscle of intrauterine growth-retarded rats.

Selak MA, Storey BT, Peterside I, Simmons RA.

Am J Physiol Endocrinol Metab. 2003 Jul;285(1):E130-7. Epub 2003 Mar 11.PMID: 12637257 [PubMed - indexed for MEDLINE]Related articlesFree article

Neonatal exendin-4 prevents the development of diabetes in the intrauterine growth retarded rat.

Stoffers DA, Desai BM, DeLeon DD, Simmons RA.

Diabetes. 2003 Mar;52(3):734-40.PMID: 12606515 [PubMed - indexed for MEDLINE]Related articlesFree article

Placental expression of insulin-like growth factor receptor-1 and insulin receptor in the growth-restricted fetal rat.

Reid GJ, Flozak AS, Simmons RA.

J Soc Gynecol Investig. 2002 Jul-Aug;9(4):210-4.PMID: 12113879 [PubMed - indexed for MEDLINE]Related articles

Gestational diabetes leads to the development of diabetes in adulthood in the rat.

Boloker J, Gertz SJ, Simmons RA.

Diabetes. 2002 May;51(5):1499-506.PMID: 11978648 [PubMed - indexed for MEDLINE]Related articlesFree article

Intrauterine growth retardation leads to the development of type 2 diabetes in the rat.

Simmons RA, Templeton LJ, Gertz SJ.

Diabetes. 2001 Oct;50(10):2279-86.PMID: 11574409 [PubMed - indexed for MEDLINE]Related articlesFree article

Workshop to identify critical windows of exposure for children's health: cardiovascular and endocrine work group summary.

Barr M Jr, DeSesso JM, Lau CS, Osmond C, Ozanne SE, Sadler TW, Simmons RA, Sonawane BR.

Environ Health Perspect. 2000 Jun;108 Suppl 3:569-71. Review.PMID: 10852856 [PubMed - indexed for MEDLINE]Related articlesFree article

Placental expression of glucose transporter proteins 1 and 3 in growth-restricted fetal rats.

Reid GJ, Lane RH, Flozak AS, Simmons RA.

Am J Obstet Gynecol. 1999 Apr;180(4):1017-23.PMID: 10203672 [PubMed - indexed for MEDLINE]Related articles

Localization and quantification of glucose transporters in liver of growth-retarded fetal and neonatal rats.

Lane RH, Crawford SE, Flozak AS, Simmons RA.

Am J Physiol. 1999 Jan;276(1 Pt 1):E135-42.PMID: 9886959 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of uteroplacental insufficiency upon brain neuropeptide Y and corticotropin-releasing factor gene expression and concentrations.

Rajakumar PA, He J, Simmons RA, Devaskar SU.

Pediatr Res. 1998 Aug;44(2):168-74.PMID: 9702909 [PubMed - indexed for MEDLINE]Related articles

Modulation of glucose transport in fetal rat lung: a sexual dimorphism.

Hart CD, Flozak AS, Simmons RA.

Am J Respir Cell Mol Biol. 1998 Jul;19(1):63-70.PMID: 9651181 [PubMed - indexed for MEDLINE]Related articlesFree article

Intrauterine growth retardation alters mitochondrial gene expression and function in fetal and juvenile rat skeletal muscle.

Lane RH, Chandorkar AK, Flozak AS, Simmons RA.

Pediatr Res. 1998 May;43(5):563-70.PMID: 9585000 [PubMed - indexed for MEDLINE]Related articles

Cutaneous necrosis associated with interferon alpha-2b.

Sickler JB, Simmons RA, Cobb DK, Sherman KE.

Am J Gastroenterol. 1998 Mar;93(3):463-4.PMID: 9517660 [PubMed - indexed for MEDLINE]Related articles

Measurement of GLUT mRNA in liver of fetal and neonatal rats using a novel method of quantitative polymerase chain reaction.

Lane RH, Flozak AS, Simmons RA.

Biochem Mol Med. 1996 Dec;59(2):192-9.PMID: 8986644 [PubMed - indexed for MEDLINE]Related articles

Altered hepatic gene expression of enzymes involved in energy metabolism in the growth-retarded fetal rat.

Lane RH, Flozak AS, Ogata ES, Bell GI, Simmons RA.

Pediatr Res. 1996 Mar;39(3):390-4.PMID: 8929856 [PubMed - indexed for MEDLINE]Related articles

The effects of severe maternal diabetes on glucose transport in the fetal rat.

Atkins V, Flozak AS, Ogata ES, Simmons RA.

Endocrinology. 1994 Jul;135(1):409-15.PMID: 8013378 [PubMed - indexed for MEDLINE]Related articles

The effect of insulin and insulin-like growth factor-I on glucose transport in normal and small for gestational age fetal rats.

Simmons RA, Flozak AS, Ogata ES.

Endocrinology. 1993 Sep;133(3):1361-8.PMID: 8365373 [PubMed - indexed for MEDLINE]Related articles

Glucose regulates glut 1 function and expression in fetal rat lung and muscle in vitro.

Simmons RA, Flozak AS, Ogata ES.

Endocrinology. 1993 Jun;132(6):2312-8.PMID: 8504736 [PubMed - indexed for MEDLINE]Related articles

Circulating levels of insulin, insulin-like growth factor-I (IGF-I), IGF-II, and IGF-binding proteins in the small for gestational age fetal rat.

Unterman TG, Simmons RA, Glick RP, Ogata ES.

Endocrinology. 1993 Jan;132(1):327-36.PMID: 7678218 [PubMed - indexed for MEDLINE]Related articles

Intrauterine growth retardation: fetal glucose transport is diminished in lung but spared in brain.

Simmons RA, Gounis AS, Bangalore SA, Ogata ES.

Pediatr Res. 1992 Jan;31(1):59-63.PMID: 1594332 [PubMed - indexed for MEDLINE]Related articles

Screening radon risks: a methodology for policymakers.

Eisinger DS, Simmons RA, Lammering M, Sotiros R.

Regul Toxicol Pharmacol. 1991 Dec;14(3):245-60. Review.PMID: 1771267 [PubMed - indexed for MEDLINE]Related articles

Circulating levels of insulin-like growth factor binding protein-1 (IGFBP-1) and hepatic mRNA are increased in the small for gestational age (SGA) fetal rat.

Unterman T, Lascon R, Gotway MB, Oehler D, Gounis A, Simmons RA, Ogata ES.

Endocrinology. 1990 Oct;127(4):2035-7. Erratum in: Endocrinology 1991 Jan;128(1):400. PMID: 1698152 [PubMed - indexed for MEDLINE]Related articles

Late gestation alterations in fetal pulmonary lactate metabolism in vivo.

Simmons RA, Charlton VE.

Pediatr Res. 1990 Mar;27(3):274-7.PMID: 2320394 [PubMed - indexed for MEDLINE]Related articles

Substrate utilization by the fetal sheep lung during the last trimester.

Simmons RA, Charlton VE.

Pediatr Res. 1988 Jun;23(6):606-11.PMID: 3393394 [PubMed - indexed for MEDLINE]Related articles

An outbreak of amebiasis spread by colonic irrigation at a chiropractic clinic.

Istre GR, Kreiss K, Hopkins RS, Healy GR, Benziger M, Canfield TM, Dickinson P, Englert TR, Compton RC, Mathews HM, Simmons RA.

N Engl J Med. 1982 Aug 5;307(6):339-42.PMID: 6283354 [PubMed - indexed for MEDLINE]Related articles

Unrecognized intraoperative torsion of the lung.

Oddi MA, Traugott RC, Will RJ, Simmons RA, Treasure RL, Schuchmann GF.

Surgery. 1981 Mar;89(3):390-3.PMID: 7466631 [PubMed - indexed for MEDLINE]Related articles

Carbenicillin and pseudomembranous enterocolitis.

O'Meara TF, Simmons RA.

Ann Intern Med. 1980 Mar;92(3):440-1. No abstract available. PMID: 7356253 [PubMed - indexed for MEDLINE]Related articles

Clinical variability of the gouty diathesis.

Arnold WJ, Simmons RA.

Adv Exp Med Biol. 1980;122A:39-46. No abstract available. PMID: 6252756 [PubMed - indexed for MEDLINE]Related articles

Use of 111In-labeled leukocytes in evaluation of renal transplant rejection: a preliminary report.

Frick MP, Henke CE, Forstrom LA, Simmons RA, McCullough J, Loken MK.

Clin Nucl Med. 1979 Jan;4(1):24-5. No abstract available. PMID: 369760 [PubMed - indexed for MEDLINE]Related articles

Skin lesions in paroxysmal nocturnal hemoglobinuria.

Rietschel RL, Lewis CW, Simmons RA, Phyliky RL.

Arch Dermatol. 1978 Apr;114(4):560-3.PMID: 565618 [PubMed - indexed for MEDLINE]Related articles