PubMed

Sex differences in mortality following acute coronary syndromes.

Berger JS, Elliott L, Gallup D, Roe M, Granger CB, Armstrong PW, Simes RJ, White HD, Van de Werf F, Topol EJ, Hochman JS, Newby LK, Harrington RA, Califf RM, Becker RC, Douglas PS.

JAMA. 2009 Aug 26;302(8):874-82.PMID: 19706861 [PubMed - indexed for MEDLINE]Related articles

Deriving a Patient-Based Utility Index from a Cancer-Specific Quality of Life Questionnaire.

Grimison PS, Simes RJ, Hudson HM, Stockler MR.

Value Health. 2009 Mar 10. [Epub ahead of print]PMID: 19508665 [PubMed - as supplied by publisher]Related articles

Preliminary validation of an optimally weighted patient-based utility index by application to randomized trials in breast cancer.

Grimison PS, Simes RJ, Hudson HM, Stockler MR.

Value Health. 2009 Sep;12(6):967-76. Epub 2009 Mar 16.PMID: 19490566 [PubMed - indexed for MEDLINE]Related articles

Molecular biomarkers to individualise treatment: assessing the evidence.

Lee CK, Lord SJ, Coates AS, Simes RJ.

Med J Aust. 2009 Jun 1;190(11):631-6. Review.PMID: 19485842 [PubMed - indexed for MEDLINE]Related articles

Relationships of HDL cholesterol, ApoA-I, and ApoA-II with homocysteine and creatinine in patients with type 2 diabetes treated with fenofibrate.

Taskinen MR, Sullivan DR, Ehnholm C, Whiting M, Zannino D, Simes RJ, Keech AC, Barter PJ; FIELD study investigators.

Arterioscler Thromb Vasc Biol. 2009 Jun;29(6):950-5. Epub 2009 Mar 26.PMID: 19325138 [PubMed - indexed for MEDLINE]Related articles

K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

Karapetis CS, Khambata-Ford S, Jonker DJ, O'Callaghan CJ, Tu D, Tebbutt NC, Simes RJ, Chalchal H, Shapiro JD, Robitaille S, Price TJ, Shepherd L, Au HJ, Langer C, Moore MJ, Zalcberg JR.

N Engl J Med. 2008 Oct 23;359(17):1757-65.PMID: 18946061 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparing patients' and clinicians' assessment of outcomes in a randomised trial of sentinel node biopsy for breast cancer (the RACS SNAC trial).

Smith MJ, Gill PG, Wetzig N, Sourjina T, Gebski V, Ung O, Campbell I, Kollias J, Coskinas X, Macphee A, Young L, Simes RJ, Stockler MR; Royal Australasian College of Surgeons SNAC Trial Group.

Breast Cancer Res Treat. 2009 Sep;117(1):99-109. Epub 2008 Oct 17.PMID: 18925434 [PubMed - indexed for MEDLINE]Related articles

Monitoring cholesterol levels: measurement error or true change?

Glasziou PP, Irwig L, Heritier S, Simes RJ, Tonkin A; LIPID Study Investigators.

Ann Intern Med. 2008 May 6;148(9):656-61.PMID: 18458278 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparing patients' and their partners' preferences for adjuvant chemotherapy in early breast cancer.

Duric VM, Butow PN, Sharpe L, Heritier S, Boyle F, Beith J, Wilcken NR, Coates AS, Simes RJ, Stockler MR.

Patient Educ Couns. 2008 Aug;72(2):239-45. Epub 2008 Apr 22.PMID: 18434070 [PubMed - indexed for MEDLINE]Related articles

The value of N-terminal fragment of brain natriuretic peptide and tissue inhibitor of metalloproteinase-1 levels as predictors of cardiovascular outcome in the LIPID study.

West MJ, Nestel PJ, Kirby AC, Schnabel R, Sullivan D, Simes RJ, Pollicino C, Lubos E, Münzel TF, White HD, Tonkin AM, Bickel C, Tiret L, Blankenberg S; LIPID Study Investigators.

Eur Heart J. 2008 Apr;29(7):923-31. Epub 2008 Feb 22.PMID: 18296678 [PubMed - indexed for MEDLINE]Related articlesFree article

Differences in cardiovascular mortality between Australia and New Zealand according to socioeconomic status: findings from the Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study.

Stewart RA, North FM, Sharples KJ, Simes RJ, Tonkin AM, White HD; Long-term Intervention with Pravastatin in Ischaemic Disease Study Investigators.

N Z Med J. 2008 Feb 15;121(1269):11-23.PMID: 18278078 [PubMed - indexed for MEDLINE]Related articles

Can self-rated health scores be used for risk prediction in patients with type 2 diabetes?

Hayes AJ, Clarke PM, Glasziou PG, Simes RJ, Drury PL, Keech AC.

Diabetes Care. 2008 Apr;31(4):795-7. Epub 2008 Jan 9.PMID: 18184900 [PubMed - indexed for MEDLINE]Related articlesFree article

Initial aspirin dose and outcome among ST-elevation myocardial infarction patients treated with fibrinolytic therapy.

Berger JS, Stebbins A, Granger CB, Ohman EM, Armstrong PW, Van de Werf F, White HD, Simes RJ, Harrington RA, Califf RM, Peterson ED.

Circulation. 2008 Jan 15;117(2):192-9. Epub 2007 Dec 17.PMID: 18086929 [PubMed - indexed for MEDLINE]Related articlesFree article

Cetuximab for the treatment of colorectal cancer.

Jonker DJ, O'Callaghan CJ, Karapetis CS, Zalcberg JR, Tu D, Au HJ, Berry SR, Krahn M, Price T, Simes RJ, Tebbutt NC, van Hazel G, Wierzbicki R, Langer C, Moore MJ.

N Engl J Med. 2007 Nov 15;357(20):2040-8.PMID: 18003960 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of fenofibrate on the need for laser treatment for diabetic retinopathy (FIELD study): a randomised controlled trial.

Keech AC, Mitchell P, Summanen PA, O'Day J, Davis TM, Moffitt MS, Taskinen MR, Simes RJ, Tse D, Williamson E, Merrifield A, Laatikainen LT, d'Emden MC, Crimet DC, O'Connell RL, Colman PG; FIELD study investigators.

Lancet. 2007 Nov 17;370(9600):1687-97. Epub 2007 Nov 7.PMID: 17988728 [PubMed - indexed for MEDLINE]Related articles

Cardiovascular disease on a global scale: defining the path forward for research and practice.

Mark DB, Van de Werf FJ, Simes RJ, White HD, Wallentin LC, Califf RM, Armstrong PW; VIGOUR Group.

Eur Heart J. 2007 Nov;28(21):2678-84. Epub 2007 Oct 16.PMID: 17940081 [PubMed - indexed for MEDLINE]Related articlesFree article

Biases in the identification of risk factor thresholds and J-curves.

Marschner IC, Simes RJ, Keech A.

Am J Epidemiol. 2007 Oct 1;166(7):824-31. Epub 2007 Jul 21.PMID: 17644824 [PubMed - indexed for MEDLINE]Related articlesFree article

Primary percutaneous coronary intervention compared with fibrinolysis for myocardial infarction in diabetes mellitus: results from the Primary Coronary Angioplasty vs Thrombolysis-2 trial.

Timmer JR, Ottervanger JP, de Boer MJ, Boersma E, Grines CL, Westerhout CM, Simes RJ, Granger CB, Zijlstra F; Primary Coronary Angioplasty vs Thrombolysis-2 Trialists Collaborators Group.

Arch Intern Med. 2007 Jul 9;167(13):1353-9.PMID: 17620527 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of sertraline on symptoms and survival in patients with advanced cancer, but without major depression: a placebo-controlled double-blind randomised trial.

Stockler MR, O'Connell R, Nowak AK, Goldstein D, Turner J, Wilcken NR, Wyld D, Abdi EA, Glasgow A, Beale PJ, Jefford M, Dhillon H, Heritier S, Carter C, Hickie IB, Simes RJ; Zoloft's Effects on Symptoms and survival Time Trial Group.

Lancet Oncol. 2007 Jul;8(7):603-12. Erratum in: Lancet Oncol. 2007 Jul 8;8(7):574. PMID: 17548243 [PubMed - indexed for MEDLINE]Related articles

Variations in the use of emergency PCI for the treatment of re-infarction following intravenous fibrinolytic therapy: impact on outcomes in HERO-2.

Edmond JJ, French JK, Aylward PE, Wong CK, Stewart RA, Williams BF, De Pasquale CG, O'connell RL, Van den Berg K, Van de Werf FJ, Simes RJ, White HD; for the HERO-2 Investigators.

Eur Heart J. 2007 Jun;28(12):1418-24. Epub 2007 May 11.PMID: 17496286 [PubMed - indexed for MEDLINE]Related articlesFree article

When is measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do we need randomized trials?

Lord SJ, Irwig L, Simes RJ.

Ann Intern Med. 2006 Jun 6;144(11):850-5.PMID: 16754927 [PubMed - indexed for MEDLINE]Related articlesFree article

Statin use and sex-specific stroke outcomes in patients with vascular disease.

Bushnell CD, Griffin J, Newby LK, Goldstein LB, Mahaffey KW, Graffagnino CA, Harrington RA, White HD, Simes RJ, Califf RM, Topol EJ, Easton JD.

Stroke. 2006 Jun;37(6):1427-31. Epub 2006 Apr 27.PMID: 16645137 [PubMed - indexed for MEDLINE]Related articlesFree article

Frequency of recurrent ST-elevation myocardial infarction after fibrinolytic therapy in a different territory as a manifestation of multiple unstable coronary arterial plaques.

Edmond JJ, French JK, Stewart RA, Aylward PA, De Pasquale CG, Williams BF, O'Connell RL, Simes RJ, White HD; HERO-2 Investigators.

Am J Cardiol. 2006 Apr 1;97(7):947-51. Epub 2006 Feb 13.PMID: 16563892 [PubMed - indexed for MEDLINE]Related articles

Disarming the guarded prognosis: predicting survival in newly referred patients with incurable cancer.

Stockler MR, Tattersall MH, Boyer MJ, Clarke SJ, Beale PJ, Simes RJ.

Br J Cancer. 2006 Jan 30;94(2):208-12.PMID: 16404420 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial.

Keech A, Simes RJ, Barter P, Best J, Scott R, Taskinen MR, Forder P, Pillai A, Davis T, Glasziou P, Drury P, Kesäniemi YA, Sullivan D, Hunt D, Colman P, d'Emden M, Whiting M, Ehnholm C, Laakso M; FIELD study investigators.

Lancet. 2005 Nov 26;366(9500):1849-61. Erratum in: Lancet. 2006 Oct 21;368(9545):1415. Lancet. 2006 Oct 21;368(9545):1420. PMID: 16310551 [PubMed - indexed for MEDLINE]Related articles

Surgery alone versus chemoradiotherapy followed by surgery for resectable cancer of the oesophagus: a randomised controlled phase III trial.

Burmeister BH, Smithers BM, Gebski V, Fitzgerald L, Simes RJ, Devitt P, Ackland S, Gotley DC, Joseph D, Millar J, North J, Walpole ET, Denham JW; Trans-Tasman Radiation Oncology Group; Australasian Gastro-Intestinal Trials Group.

Lancet Oncol. 2005 Sep;6(9):659-68.PMID: 16129366 [PubMed - indexed for MEDLINE]Related articles

Patients' preferences for adjuvant chemotherapy in early breast cancer: what makes AC and CMF worthwhile now?

Duric VM, Stockler MR, Heritier S, Boyle F, Beith J, Sullivan A, Wilcken N, Coates AS, Simes RJ.

Ann Oncol. 2005 Nov;16(11):1786-94. Epub 2005 Aug 26.PMID: 16126738 [PubMed - indexed for MEDLINE]Related articlesFree article

A systematic review of taxane-containing regimens for metastatic breast cancer.

Ghersi D, Wilcken N, Simes RJ.

Br J Cancer. 2005 Aug 8;93(3):293-301. Review.PMID: 16052223 [PubMed - indexed for MEDLINE]Related articlesFree article

Patients with prolonged ischemic chest pain and presumed-new left bundle branch block have heterogeneous outcomes depending on the presence of ST-segment changes.

Wong CK, French JK, Aylward PE, Stewart RA, Gao W, Armstrong PW, Van De Werf FJ, Simes RJ, Raffel OC, Granger CB, Califf RM, White HD; HERO-2 Trial Investigators.

J Am Coll Cardiol. 2005 Jul 5;46(1):29-38.PMID: 15992631 [PubMed - indexed for MEDLINE]Related articles

Relation of diet to cardiovascular disease risk factors in subjects with cardiovascular disease in Australia and New Zealand: analysis of the Long-Term Intervention with Pravastatin in Ischaemic Disease trial.

Nestel PJ, Baghurst K, Colquhoun DM, Simes RJ, Mehalski K, White HD, Tonkin AM, Kirby A, Pollicino C; Long-Term Intervention with Pravastatin in Ischaemic Disease Study Investigators.

Am J Clin Nutr. 2005 Jun;81(6):1322-9.PMID: 15941882 [PubMed - indexed for MEDLINE]Related articlesFree article

White blood cell count predicts reduction in coronary heart disease mortality with pravastatin.

Stewart RA, White HD, Kirby AC, Heritier SR, Simes RJ, Nestel PJ, West MJ, Colquhoun DM, Tonkin AM; Long-Term Intervention With Pravastatin in Ischemic Disease (LIPID) Study Investigators.

Circulation. 2005 Apr 12;111(14):1756-62. Epub 2005 Apr 4.PMID: 15809366 [PubMed - indexed for MEDLINE]Related articlesFree article

Lessons learned from a clinical trial.

Armstrong PW, Newby LK, Granger CB, Lee KL, Simes RJ, Van de Werf F, White HD, Califf RM; Virtual Coordinating Centre for Global Collaborative Cardiovascular Research (VIGOUR) Group.

Circulation. 2004 Dec 7;110(23):3610-4. Review. No abstract available. PMID: 15583090 [PubMed - indexed for MEDLINE]Related articlesFree article

Incidence and characteristics of stroke during 90-day follow-up in patients stabilized after an acute coronary syndrome.

Kassem-Moussa H, Mahaffey KW, Graffagnino C, Tasissa G, Sila CA, Simes RJ, White HD, Califf RM, Bhapkar MV, Newby LK; SYMPHONY and 2nd SYMPHONY Investigators.

Am Heart J. 2004 Sep;148(3):439-46.PMID: 15389230 [PubMed - indexed for MEDLINE]Related articles

Subgroup analysis: application to individual patient decisions.

Simes RJ, Gebski VJ, Keech AC.

Med J Aust. 2004 May 3;180(9):467-9. No abstract available. PMID: 15115428 [PubMed - indexed for MEDLINE]Related articlesFree article

Doctors' participation in randomized trials of adjuvant systemic therapy in breast cancer: how does it relate to their recommendations for standard therapy in breast cancer?

Ellis PM, Buttow PN, Simes RJ, Tattersall MH, Dunn SM, MacLeod C.

Breast. 1999 Aug;8(4):182-7.PMID: 14731437 [PubMed]Related articles

The benefits and costs of tamoxifen for breast cancer prevention.

Eckermann SD, Martin AJ, Stockler MR, Simes RJ.

Aust N Z J Public Health. 2003;27(1):34-40.PMID: 14705265 [PubMed - indexed for MEDLINE]Related articles

International variation in the use of evidence-based medicines for acute coronary syndromes.

Kramer JM, Newby LK, Chang WC, Simes RJ, Van de Werf F, Granger CB, Lee KL, White HD, Piegas LS, Topol EJ, Califf RM, Armstrong PW; SYMPHONY and 2nd SYMPHONY Investigators.

Eur Heart J. 2003 Dec;24(23):2133-41.PMID: 14643274 [PubMed - indexed for MEDLINE]Related articlesFree article

Depression and cardiovascular morbidity and mortality: cause or consequence?

Stewart RA, North FM, West TM, Sharples KJ, Simes RJ, Colquhoun DM, White HD, Tonkin AM; Long-Term Intervention With Pravastatin in Ischaemic Disease (LIPID) Study Investigators.

Eur Heart J. 2003 Nov;24(22):2027-37.PMID: 14613739 [PubMed - indexed for MEDLINE]Related articlesFree article

Secondary prevention of cardiovascular events with long-term pravastatin in patients with diabetes or impaired fasting glucose: results from the LIPID trial.

Keech A, Colquhoun D, Best J, Kirby A, Simes RJ, Hunt D, Hague W, Beller E, Arulchelvam M, Baker J, Tonkin A; LIPID Study Group.

Diabetes Care. 2003 Oct;26(10):2713-21.PMID: 14514569 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical trials research in the new millennium: the International Clinical Trials Symposium, Sydney, 21-23 October 2002.

Pike R, Keech AC, Simes RJ.

Med J Aust. 2003 Apr 7;178(7):316-7. No abstract available. PMID: 12670271 [PubMed - indexed for MEDLINE]Related articlesFree article

An automated strategy for bedside aPTT determination and unfractionated heparin infusion adjustment in acute coronary syndromes: insights from PARAGON A.

Newby LK, Harrington RA, Bhapkar MV, Van de Werf F, Hochman JS, Granger CB, Simes RJ, Davis CG, Topol EJ, Califf RM, Moliterno DJ; PARAGON A Investigators.

J Thromb Thrombolysis. 2002 Aug;14(1):33-42.PMID: 12652148 [PubMed - indexed for MEDLINE]Related articles

Primary coronary angioplasty compared with intravenous thrombolytic therapy for acute myocardial infarction: six-month follow up and analysis of individual patient data from randomized trials.

Grines C, Patel A, Zijlstra F, Weaver WD, Granger C, Simes RJ; PCAT Collaborators. Percutaneous transluminal coronary angioplasty.

Am Heart J. 2003 Jan;145(1):47-57. Review.PMID: 12514654 [PubMed - indexed for MEDLINE]Related articles

Risk factors for non-haemorrhagic stroke in patients with coronary heart disease and the effect of lipid-modifying therapy with pravastatin.

West MJ, White HD, Simes RJ, Kirby A, Watson JD, Anderson NE, Hankey GJ, Wonders S, Hunt D, Tonkin AM.

J Hypertens. 2002 Dec;20(12):2513-7.PMID: 12473877 [PubMed - indexed for MEDLINE]Related articles

Cholesterol-lowering therapy with pravastatin in patients with average cholesterol levels and established ischaemic heart disease: is it cost-effective?

Glasziou PP, Eckermann SD, Mulray SE, Simes RJ, Martin AJ, Kirby AC, Hall JP, Caleo S, White HD, Tonkin AM.

Med J Aust. 2002 Oct 21;177(8):428-34.PMID: 12381252 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical trials and "real-world" medicine. Trial evidence best informs real-world medicine when it is relevant to the clinical problem.

Simes RJ.

Med J Aust. 2002 Oct 21;177(8):410-1. No abstract available. PMID: 12381248 [PubMed - indexed for MEDLINE]Related articlesFree article

Adjuvant immunotherapy of patients with high-risk melanoma using vaccinia viral lysates of melanoma: results of a randomized trial.

Hersey P, Coates AS, McCarthy WH, Thompson JF, Sillar RW, McLeod R, Gill PG, Coventry BJ, McMullen A, Dillon H, Simes RJ.

J Clin Oncol. 2002 Oct 15;20(20):4181-90.PMID: 12377961 [PubMed - indexed for MEDLINE]Related articles

Sustained ventricular arrhythmias among patients with acute coronary syndromes with no ST-segment elevation: incidence, predictors, and outcomes.

Al-Khatib SM, Granger CB, Huang Y, Lee KL, Califf RM, Simoons ML, Armstrong PW, Van de Werf F, White HD, Simes RJ, Moliterno DJ, Topol EJ, Harrington RA.

Circulation. 2002 Jul 16;106(3):309-12.PMID: 12119245 [PubMed - indexed for MEDLINE]Related articlesFree article

The failure of orally administered glycoprotein IIb/IIIa inhibitors to prevent recurrent cardiac events.

Newby LK, Califf RM, White HD, Harrington RA, Van de Werf F, Granger CB, Simes RJ, Hasselblad V, Armstrong PW.

Am J Med. 2002 Jun 1;112(8):647-58.PMID: 12034415 [PubMed - indexed for MEDLINE]Related articles

Clinical characteristics and outcome of patients with early (<2 h), intermediate (2-4 h) and late (>4 h) presentation treated by primary coronary angioplasty or thrombolytic therapy for acute myocardial infarction.

Zijlstra F, Patel A, Jones M, Grines CL, Ellis S, Garcia E, Grinfeld L, Gibbons RJ, Ribeiro EE, Ribichini F, Granger C, Akhras F, Weaver WD, Simes RJ.

Eur Heart J. 2002 Apr;23(7):550-7.PMID: 11922645 [PubMed - indexed for MEDLINE]Related articles

Relationship between lipid levels and clinical outcomes in the Long-term Intervention with Pravastatin in Ischemic Disease (LIPID) Trial: to what extent is the reduction in coronary events with pravastatin explained by on-study lipid levels?

Simes RJ, Marschner IC, Hunt D, Colquhoun D, Sullivan D, Stewart RA, Hague W, Keech A, Thompson P, White H, Shaw J, Tonkin A; LIPID Study Investigators.

Circulation. 2002 Mar 12;105(10):1162-9.PMID: 11889008 [PubMed - indexed for MEDLINE]Related articlesFree article