PubMed

The interferon-induced helicase IFIH1 Ala946Thr polymorphism is associated with type 1 diabetes in both the high-incidence Finnish and the medium-incidence Hungarian populations.

Jermendy A, Szatmári I, Laine AP, Lukács K, Horváth KH, Körner A, Madácsy L, Veijola R, Simell O, Knip M, Ilonen J, Hermann R; The Finnish Paediatric Diabetes Registry; The HUNT1DGENES Programme.

Diabetologia. 2009 Oct 20. [Epub ahead of print]PMID: 19841890 [PubMed - as supplied by publisher]Related articles

Systemic T-helper and T-regulatory cell type cytokine responses in rhinovirus vs. respiratory syncytial virus induced early wheezing: an observational study.

Jartti T, Paul-Anttila M, Lehtinen P, Parikka V, Vuorinen T, Simell O, Ruuskanen O.

Respir Res. 2009 Sep 25;10:85.PMID: 19781072 [PubMed - in process]Related articlesFree article

Predictive characteristics of diabetes-associated autoantibodies among children with HLA-conferred disease susceptibility in the general population.

Siljander HT, Simell S, Hekkala A, Lähde J, Simell T, Vähäsalo P, Veijola R, Ilonen J, Simell O, Knip M.

Diabetes. 2009 Dec;58(12):2835-42. Epub 2009 Sep 15.PMID: 19755526 [PubMed - in process]Related articles

From genetic risk awareness to overt type 1 diabetes: parental stress in a placebo-controlled prevention trial.

Goldstein E, Hermann R, Renfors TJ, Näntö-Salonen KM, Korhonen T, Kärkkäinen M, Veijola RK, Knip M, Simell TT, Simell OG.

Diabetes Care. 2009 Dec;32(12):2181-3. Epub 2009 Sep 14.PMID: 19752173 [PubMed - in process]Related articlesFree article

Early introduction of oats associated with decreased risk of persistent asthma and early introduction of fish with decreased risk of allergic rhinitis.

Virtanen SM, Kaila M, Pekkanen J, Kenward MG, Uusitalo U, Pietinen P, Kronberg-Kippilä C, Hakulinen T, Simell O, Ilonen J, Veijola R, Knip M.

Br J Nutr. 2009 Aug 13:1-8. [Epub ahead of print]PMID: 19674492 [PubMed - as supplied by publisher]Related articles

Role of insulin autoantibody affinity as a predictive marker for type 1 diabetes in young children with HLA-conferred disease susceptibility.

Siljander H, Härkönen T, Hermann R, Simell S, Hekkala A, Salonsaari RT, Simell T, Simell O, Ilonen J, Veijola R, Knip M.

Diabetes Metab Res Rev. 2009 Oct;25(7):615-22.PMID: 19637309 [PubMed - in process]Related articles

Carbohydrate intake, serum lipids and apolipoprotein E phenotype show association in children.

Ruottinen S, Rönnemaa T, Niinikoski H, Lagström H, Saarinen M, Pahkala K, Kaitosaari T, Viikari J, Simell O.

Acta Paediatr. 2009 Oct;98(10):1667-73. Epub 2009 Jun 26.PMID: 19563454 [PubMed - in process]Related articles

Maternal vitamin D intake during pregnancy is inversely associated with asthma and allergic rhinitis in 5-year-old children.

Erkkola M, Kaila M, Nwaru BI, Kronberg-Kippilä C, Ahonen S, Nevalainen J, Veijola R, Pekkanen J, Ilonen J, Simell O, Knip M, Virtanen SM.

Clin Exp Allergy. 2009 Jun;39(6):875-82.PMID: 19522996 [PubMed - indexed for MEDLINE]Related articles

Interplay between PTPN22 C1858T polymorphism and cow's milk formula exposure in type 1 diabetes.

Lempainen J, Vaarala O, Mäkelä M, Veijola R, Simell O, Knip M, Hermann R, Ilonen J.

J Autoimmun. 2009 Sep;33(2):155-64. Epub 2009 May 26.PMID: 19473815 [PubMed - indexed for MEDLINE]Related articles

Influence of fecal sample storage on bacterial community diversity.

Roesch LF, Casella G, Simell O, Krischer J, Wasserfall CH, Schatz D, Atkinson MA, Neu J, Triplett EW.

Open Microbiol J. 2009;3:40-6. Epub 2009 Mar 24.PMID: 19440250 [PubMed - in process]Related articlesFree article

Association of CTLA4 but not ICOS polymorphisms with type 1 diabetes in two populations with different disease rates.

Douroudis K, Laine AP, Heinonen M, Hermann R, Lipponen K, Veijola R, Simell O, Knip M, Uibo R, Ilonen J, Kisand K.

Hum Immunol. 2009 Jul;70(7):536-9. Epub 2009 Apr 17.PMID: 19376178 [PubMed - indexed for MEDLINE]Related articles

Blood pressure is lower in children and adolescents with a low-saturated-fat diet since infancy: the special turku coronary risk factor intervention project.

Niinikoski H, Jula A, Viikari J, Rönnemaa T, Heino P, Lagström H, Jokinen E, Simell O.

Hypertension. 2009 Jun;53(6):918-24. Epub 2009 Apr 13.PMID: 19364991 [PubMed - indexed for MEDLINE]Related articles

Unhealthy dietary patterns are associated with weight gain during pregnancy among Finnish women.

Uusitalo U, Arkkola T, Ovaskainen ML, Kronberg-Kippilä C, Kenward MG, Veijola R, Simell O, Knip M, Virtanen SM.

Public Health Nutr. 2009 Dec;12(12):2392-9. Epub 2009 Mar 27.PMID: 19323867 [PubMed - in process]Related articles

PCR inhibition in stool samples in relation to age of infants.

Oikarinen S, Tauriainen S, Viskari H, Simell O, Knip M, Virtanen S, Hyöty H.

J Clin Virol. 2009 Mar;44(3):211-4. Epub 2009 Feb 3.PMID: 19196549 [PubMed - indexed for MEDLINE]Related articles

Decreased aortic elasticity in healthy 11-year-old children exposed to tobacco smoke.

Kallio K, Jokinen E, Hämäläinen M, Saarinen M, Volanen I, Kaitosaari T, Viikari J, Rönnemaa T, Simell O, Raitakari OT.

Pediatrics. 2009 Feb;123(2):e267-73.PMID: 19171579 [PubMed - indexed for MEDLINE]Related articles

FTO genotype is associated with body mass index after the age of seven years but not with energy intake or leisure-time physical activity.

Hakanen M, Raitakari OT, Lehtimäki T, Peltonen N, Pahkala K, Sillanmäki L, Lagström H, Viikari J, Simell O, Rönnemaa T.

J Clin Endocrinol Metab. 2009 Apr;94(4):1281-7. Epub 2009 Jan 21.PMID: 19158205 [PubMed - indexed for MEDLINE]Related articles

The initiatives and outcomes for cardiovascular risks that can be achieved through paediatric counselling.

Viikari J, Niinikoski H, Raitakari OT, Simell O.

Curr Opin Lipidol. 2009 Feb;20(1):17-23. Review.PMID: 19106707 [PubMed - indexed for MEDLINE]Related articles

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes.

Oresic M, Simell S, Sysi-Aho M, Näntö-Salonen K, Seppänen-Laakso T, Parikka V, Katajamaa M, Hekkala A, Mattila I, Keskinen P, Yetukuri L, Reinikainen A, Lähde J, Suortti T, Hakalax J, Simell T, Hyöty H, Veijola R, Ilonen J, Lahesmaa R, Knip M, Simell O.

J Exp Med. 2008 Dec 22;205(13):2975-84. Epub 2008 Dec 15.PMID: 19075291 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of common familial dyslipidemias in early childhood.

Lapinleimu J, Lapinleimu H, Nuotio IO, Rönnemaa T, Simell OG, Viikari JS; STRIP study group.

Atherosclerosis. 2009 Jun;204(2):573-9. Epub 2008 Oct 14.PMID: 19026413 [PubMed - indexed for MEDLINE]Related articles

Parental and childhood overweight in sedentary and active adolescents.

Pahkala K, Heinonen OJ, Lagström H, Hakala P, Sillanmäki L, Kaitosaari T, Viikari J, Aromaa M, Simell O.

Scand J Med Sci Sports. 2008 Nov 5. [Epub ahead of print]PMID: 19017296 [PubMed - as supplied by publisher]Related articles

Vascular endothelial function and leisure-time physical activity in adolescents.

Pahkala K, Heinonen OJ, Lagström H, Hakala P, Simell O, Viikari JS, Rönnemaa T, Hernelahti M, Sillanmäki L, Raitakari OT.

Circulation. 2008 Dec 2;118(23):2353-9. Epub 2008 Nov 17.PMID: 19015403 [PubMed - indexed for MEDLINE]Related articles

Growth patterns and obesity development in overweight or normal-weight 13-year-old adolescents: the STRIP study.

Lagström H, Hakanen M, Niinikoski H, Viikari J, Rönnemaa T, Saarinen M, Pahkala K, Simell O.

Pediatrics. 2008 Oct;122(4):e876-83.PMID: 18829786 [PubMed - indexed for MEDLINE]Related articlesFree article

Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial.

Näntö-Salonen K, Kupila A, Simell S, Siljander H, Salonsaari T, Hekkala A, Korhonen S, Erkkola R, Sipilä JI, Haavisto L, Siltala M, Tuominen J, Hakalax J, Hyöty H, Ilonen J, Veijola R, Simell T, Knip M, Simell O.

Lancet. 2008 Nov 15;372(9651):1746-55. Epub 2008 Sep 22.PMID: 18814906 [PubMed - indexed for MEDLINE]Related articles

Arterial intima-media thickness in 13-year-old adolescents and previous antichlamydial antimicrobial use: a retrospective follow-up study.

Volanen I, Kallio K, Saarinen M, Järvisalo MJ, Vainionpää R, Rönnemaa T, Viikari J, Marniemi J, Simell O, Raitakari OT.

Pediatrics. 2008 Sep;122(3):e675-81.PMID: 18762502 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of pancreas tissue in a child positive for islet cell antibodies.

Oikarinen M, Tauriainen S, Honkanen T, Vuori K, Karhunen P, Vasama-Nolvi C, Oikarinen S, Verbeke C, Blair GE, Rantala I, Ilonen J, Simell O, Knip M, Hyöty H.

Diabetologia. 2008 Oct;51(10):1796-802. Epub 2008 Aug 12.PMID: 18696046 [PubMed - indexed for MEDLINE]Related articles

Intake of antioxidant vitamins and trace elements during pregnancy and risk of advanced beta cell autoimmunity in the child.

Uusitalo L, Kenward MG, Virtanen SM, Uusitalo U, Nevalainen J, Niinistö S, Kronberg-Kippilä C, Ovaskainen ML, Marjamäki L, Simell O, Ilonen J, Veijola R, Knip M.

Am J Clin Nutr. 2008 Aug;88(2):458-64.PMID: 18689383 [PubMed - indexed for MEDLINE]Related articlesFree article

Tracking and determinants of LDL particle size in healthy children from 7 to 11 years of age: the STRIP Study.

Kaitosaari T, Simell O, Viikari J, Raitakari O, Siltala M, Hakanen M, Leino A, Jokinen E, Rönnemaa T.

Eur J Pediatr. 2009 May;168(5):531-9. Epub 2008 Jul 5.PMID: 18604555 [PubMed - indexed for MEDLINE]Related articles

T-cell reactivity to insulin peptide A1-12 in children with recently diagnosed type 1 diabetes or multiple beta-cell autoantibodies.

Marttila J, Huttunen S, Vaarala O, Suzuki K, Elliott JF, Närvänen A, Knip M, Simell O, Ilonen J.

J Autoimmun. 2008 Sep;31(2):142-8. Epub 2008 Jun 18.PMID: 18565729 [PubMed - indexed for MEDLINE]Related articles

Gender-dependent progression of systemic metabolic states in early childhood.

Nikkilä J, Sysi-Aho M, Ermolov A, Seppänen-Laakso T, Simell O, Kaski S, Oresic M.

Mol Syst Biol. 2008;4:197. Epub 2008 Jun 3.PMID: 18523432 [PubMed - indexed for MEDLINE]Related articlesFree article

High sucrose intake is associated with poor quality of diet and growth between 13 months and 9 years of age: the special Turku Coronary Risk Factor Intervention Project.

Ruottinen S, Niinikoski H, Lagström H, Rönnemaa T, Hakanen M, Viikari J, Jokinen E, Simell O.

Pediatrics. 2008 Jun;121(6):e1676-85.PMID: 18519471 [PubMed - indexed for MEDLINE]Related articlesFree article

Agreement between parental reports and patient records in food allergies among infants and young children in Finland.

Tuokkola J, Kaila M, Pietinen P, Simell O, Knip M, Virtanen SM.

J Eval Clin Pract. 2008 Dec;14(6):984-9. Epub 2008 May 2.PMID: 18462278 [PubMed - indexed for MEDLINE]Related articles

Temporal relationship between human parechovirus 1 infection and otitis media in young children.

Tauriainen S, Oikarinen S, Taimen K, Laranne J, Sipilä M, Lönnrot M, Ilonen J, Simell O, Knip M, Hyöty H.

J Infect Dis. 2008 Jul 1;198(1):35-40.PMID: 18462136 [PubMed - indexed for MEDLINE]Related articles

Cohort Profile: the STRIP Study (Special Turku Coronary Risk Factor Intervention Project), an Infancy-onset Dietary and Life-style Intervention Trial.

Simell O, Niinikoski H, Rönnemaa T, Raitakari OT, Lagström H, Laurinen M, Aromaa M, Hakala P, Jula A, Jokinen E, Välimäki I, Viikari J; STRIP Study Group.

Int J Epidemiol. 2009 Jun;38(3):650-5. Epub 2008 Apr 22. No abstract available. PMID: 18430753 [PubMed - indexed for MEDLINE]Related articles

Relation among mannose-binding lectin 2 genotype, beta-cell autoantibodies, and risk for type 1 diabetes in Finnish children.

Aittoniemi J, Turpeinen H, Tiittanen M, Knip M, Simell O, Ilonen J, Vaarala O.

Hum Immunol. 2008 Feb;69(2):108-11. Epub 2008 Feb 20.PMID: 18361935 [PubMed - indexed for MEDLINE]Related articles

Carnitine deficiency and L-carnitine supplementation in lysinuric protein intolerance.

Tanner LM, Näntö-Salonen K, Rashed MS, Kotilainen S, Aalto M, Venetoklis J, Niinikoski H, Huoponen K, Simell O.

Metabolism. 2008 Apr;57(4):549-54.PMID: 18328359 [PubMed - indexed for MEDLINE]Related articles

Serum alpha- and gamma-tocopherol concentrations and risk of advanced beta cell autoimmunity in children with HLA-conferred susceptibility to type 1 diabetes mellitus.

Uusitalo L, Nevalainen J, Niinistö S, Alfthan G, Sundvall J, Korhonen T, Kenward MG, Oja H, Veijola R, Simell O, Ilonen J, Knip M, Virtanen SM.

Diabetologia. 2008 May;51(5):773-80. Epub 2008 Mar 4.PMID: 18317723 [PubMed - indexed for MEDLINE]Related articles

Reduced CD4+T cell activation in children with type 1 diabetes carrying the PTPN22/Lyp 620Trp variant.

Aarnisalo J, Treszl A, Svec P, Marttila J, Oling V, Simell O, Knip M, Körner A, Madacsy L, Vasarhelyi B, Ilonen J, Hermann R.

J Autoimmun. 2008 Aug;31(1):13-21. Epub 2008 Mar 4.PMID: 18299186 [PubMed - indexed for MEDLINE]Related articles

Pancreatic glucose uptake in vivo in men with newly diagnosed type 1 diabetes.

Kalliokoski T, Nuutila P, Virtanen KA, Iozzo P, Bucci M, Svedström E, Roivainen A, Någren K, Viljanen T, Minn H, Knuuti J, Rönnemaa T, Simell O.

J Clin Endocrinol Metab. 2008 May;93(5):1909-14. Epub 2008 Feb 19.PMID: 18285422 [PubMed - indexed for MEDLINE]Related articlesFree article

Cytomegalovirus infection in early infancy: risk of induction and progression of autoimmunity associated with type 1 diabetes.

Aarnisalo J, Veijola R, Vainionpää R, Simell O, Knip M, Ilonen J.

Diabetologia. 2008 May;51(5):769-72. Epub 2008 Feb 16.PMID: 18278478 [PubMed - indexed for MEDLINE]Related articles

A high-throughput population screening system for the estimation of genetic risk for type 1 diabetes: an application for the TEDDY (the Environmental Determinants of Diabetes in the Young) study.

Kiviniemi M, Hermann R, Nurmi J, Ziegler AG, Knip M, Simell O, Veijola R, Lövgren T, Ilonen J; TEDDY Study Group.

Diabetes Technol Ther. 2007 Oct;9(5):460-72.PMID: 17931054 [PubMed - indexed for MEDLINE]Related articles

Circulating CD4+CD25 high regulatory T cells and natural killer T cells in children with newly diagnosed type 1 diabetes or with diabetes-associated autoantibodies.

Oling V, Marttila J, Knip M, Simell O, Ilonen J.

Ann N Y Acad Sci. 2007 Jun;1107:363-72.PMID: 17804564 [PubMed - indexed for MEDLINE]Related articles

Antibody responses to deamidated gliadin peptide show high specificity and parallel antibodies to tissue transglutaminase in developing coeliac disease.

Ankelo M, Kleimola V, Simell S, Simell O, Knip M, Jokisalo E, Tarkia M, Westerlund A, He Q, Viander M, Ilonen J, Hinkkanen AE.

Clin Exp Immunol. 2007 Nov;150(2):285-93. Epub 2007 Sep 4.PMID: 17803713 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of repeated dietary counseling between infancy and 14 years of age on dietary intakes and serum lipids and lipoproteins: the STRIP study.

Niinikoski H, Lagström H, Jokinen E, Siltala M, Rönnemaa T, Viikari J, Raitakari OT, Jula A, Marniemi J, Näntö-Salonen K, Simell O.

Circulation. 2007 Aug 28;116(9):1032-40. Epub 2007 Aug 13.PMID: 17698729 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 1 diabetic serum interferes with pancreatic beta-cell Ca2+-handling.

Dekki N, Nilsson R, Norgren S, Rössner SM, Appelskog I, Marcus C, Simell O, Pugliese A, Alejandro R, Ricordi C, Berggren PO, Juntti-Berggren L.

Biosci Rep. 2007 Dec;27(6):321-6.PMID: 17597394 [PubMed - indexed for MEDLINE]Related articles

Nutrient intake in lysinuric protein intolerance.

Tanner LM, Näntö-Salonen K, Venetoklis J, Kotilainen S, Niinikoski H, Huoponen K, Simell O.

J Inherit Metab Dis. 2007 Oct;30(5):716-21. Epub 2007 Jun 21.PMID: 17588131 [PubMed - indexed for MEDLINE]Related articles

Fate of five celiac disease-associated antibodies during normal diet in genetically at-risk children observed from birth in a natural history study.

Simell S, Hoppu S, Hekkala A, Simell T, Ståhlberg MR, Viander M, Yrjänäinen H, Grönlund J, Markula P, Simell V, Knip M, Ilonen J, Hyöty H, Simell O.

Am J Gastroenterol. 2007 Sep;102(9):2026-35. Epub 2007 Jun 15.PMID: 17573785 [PubMed - indexed for MEDLINE]Related articles

Heterodimerization of y(+)LAT-1 and 4F2hc visualized by acceptor photobleaching FRET microscopy.

Kleemola M, Toivonen M, Mykkänen J, Simell O, Huoponen K, Heiskanen KM.

Biochim Biophys Acta. 2007 Oct;1768(10):2345-54. Epub 2007 May 3.PMID: 17560897 [PubMed - indexed for MEDLINE]Related articles

Tobacco smoke exposure is associated with attenuated endothelial function in 11-year-old healthy children.

Kallio K, Jokinen E, Raitakari OT, Hämäläinen M, Siltala M, Volanen I, Kaitosaari T, Viikari J, Rönnemaa T, Simell O.

Circulation. 2007 Jun 26;115(25):3205-12. Epub 2007 Jun 4.PMID: 17548727 [PubMed - indexed for MEDLINE]Related articlesFree article

Nephropathy advancing to end-stage renal disease: a novel complication of lysinuric protein intolerance.

Tanner LM, Näntö-Salonen K, Niinikoski H, Jahnukainen T, Keskinen P, Saha H, Kananen K, Helanterä A, Metso M, Linnanvuo M, Huoponen K, Simell O.

J Pediatr. 2007 Jun;150(6):631-4, 634.e1.PMID: 17517249 [PubMed - indexed for MEDLINE]Related articles

Two insulin gene single nucleotide polymorphisms associated with type 1 diabetes risk in the Finnish and Swedish populations.

Laine AP, Holmberg H, Nilsson A, Ortqvist E, Kiviniemi M, Vaarala O, Akerblom HK, Simell O, Knip M, Ludvigsson J, Ivarsson SA, Larsson K, Lernmark A, Ilonen J; Finnish Paediatric Diabetes Registry.

Dis Markers. 2007;23(3):139-45.PMID: 17473382 [PubMed - indexed for MEDLINE]Related articlesFree article