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The Biology Of Allogeneic Hematopoietic Cell Resistance.

Shizuru JA, Bhattacharya D, Cavazzana-Calvo M.

Biol Blood Marrow Transplant. 2009 Nov 11. [Epub ahead of print] No abstract available. PMID: 19913629 [PubMed - as supplied by publisher]Related articles

Ineffective Vaccination against Solid Tumors Can Be Enhanced by Hematopoietic Cell Transplantation.

Filatenkov A, Müller AM, Tseng WW, Dejbakhsh-Jones S, Winer D, Luong R, Shizuru JA, Engleman EG, Strober S.

J Immunol. 2009 Dec 1;183(11):7196-7203. Epub 2009 Nov 4.PMID: 19890041 [PubMed - as supplied by publisher]Related articles

Salvage allogeneic hematopoietic cell transplantation with fludarabine and low-dose total body irradiation after rejection of first allografts.

Gyurkocza B, Cao TM, Storb RF, Lange T, Leisenring W, Franke GN, Sorror M, Hoppe R, Maloney DG, Negrin RS, Shizuru JA, Sandmaier BM.

Biol Blood Marrow Transplant. 2009 Oct;15(10):1314-22. Epub 2009 Aug 3.PMID: 19747640 [PubMed - in process]Related articles

Long-term follow-up of patients with diffuse large B-cell non-Hodgkin's lymphoma receiving purged autografts after induction failure.

Benjamin JE, Chen GL, Cao TM, Cao PD, Wong RM, Sheehan K, Shizuru JA, Johnston LJ, Negrin RS, Lowksy R, Laport GG.

Bone Marrow Transplant. 2009 Jul 13. [Epub ahead of print]PMID: 19597427 [PubMed - as supplied by publisher]Related articles

Identification of a major susceptibility locus for lethal graft-versus-host disease in MHC-matched mice.

Cao TM, Lazzeroni LC, Tsai S, Pang WW, Kao A, Camp NJ, Thomas A, Shizuru JA.

J Immunol. 2009 Jul 1;183(1):462-9. Epub 2009 Jun 12.PMID: 19525392 [PubMed - indexed for MEDLINE]Related articles

TLI and ATG conditioning with low risk of graft-versus-host disease retains antitumor reactions after allogeneic hematopoietic cell transplantation from related and unrelated donors.

Kohrt HE, Turnbull BB, Heydari K, Shizuru JA, Laport GG, Miklos DB, Johnston LJ, Arai S, Weng WK, Hoppe RT, Lavori PW, Blume KG, Negrin RS, Strober S, Lowsky R.

Blood. 2009 Jul 30;114(5):1099-109. Epub 2009 May 7.PMID: 19423725 [PubMed - indexed for MEDLINE]Related articles

A chromosome 16 quantitative trait locus regulates allogeneic bone marrow engraftment in nonmyeloablated mice.

Cao TM, Thomas A, Wang Y, Tsai S, Logronio K, Shizuru JA.

Blood. 2009 Jul 2;114(1):202-10. Epub 2009 May 5.PMID: 19417206 [PubMed - indexed for MEDLINE]Related articles

Purified hematopoietic stem cell allografts reconstitute immunity superior to bone marrow.

Tsao GJ, Allen JA, Logronio KA, Lazzeroni LC, Shizuru JA.

Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3288-93. Epub 2009 Feb 17.PMID: 19223585 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term outcome of patients with multiple myeloma after autologous hematopoietic cell transplantation and nonmyeloablative allografting.

Rotta M, Storer BE, Sahebi F, Shizuru JA, Bruno B, Lange T, Agura ED, McSweeney PA, Pulsipher MA, Hari P, Maziarz RT, Chauncey TR, Appelbaum FR, Sorror ML, Bensinger W, Sandmaier BM, Storb RF, Maloney DG.

Blood. 2009 Apr 2;113(14):3383-91. Epub 2008 Nov 17.PMID: 19015394 [PubMed - indexed for MEDLINE]Related articles

The origins of the identification and isolation of hematopoietic stem cells, and their capability to induce donor-specific transplantation tolerance and treat autoimmune diseases.

Weissman IL, Shizuru JA.

Blood. 2008 Nov 1;112(9):3543-53. Review.PMID: 18948588 [PubMed - indexed for MEDLINE]Related articlesFree article

Complementing mutations in core binding factor leukemias: from mouse models to clinical applications.

Müller AM, Duque J, Shizuru JA, Lübbert M.

Oncogene. 2008 Oct 2;27(44):5759-73. Epub 2008 Jul 7. Review.PMID: 18604246 [PubMed - indexed for MEDLINE]Related articles

Tolerance and chimerism after renal and hematopoietic-cell transplantation.

Scandling JD, Busque S, Dejbakhsh-Jones S, Benike C, Millan MT, Shizuru JA, Hoppe RT, Lowsky R, Engleman EG, Strober S.

N Engl J Med. 2008 Jan 24;358(4):362-8.PMID: 18216356 [PubMed - indexed for MEDLINE]Related articlesFree article

Extended mycophenolate mofetil and shortened cyclosporine failed to reduce graft-versus-host disease after unrelated hematopoietic cell transplantation with nonmyeloablative conditioning.

Baron F, Sandmaier BM, Storer BE, Maris MB, Langston AA, Lange T, Petersdorf E, Bethge W, Maziarz RT, McSweeney PA, Pulsipher MA, Wade JC, Chauncey TR, Shizuru JA, Sorror ML, Woolfrey AE, Maloney DG, Storb R.

Biol Blood Marrow Transplant. 2007 Sep;13(9):1041-8. Epub 2007 Jul 20.PMID: 17697966 [PubMed - indexed for MEDLINE]Related articlesFree article

Nonmyeloablative unrelated donor hematopoietic cell transplantation to treat patients with poor-risk, relapsed, or refractory multiple myeloma.

Georges GE, Maris MB, Maloney DG, Sandmaier BM, Sorror ML, Shizuru JA, Lange T, Agura ED, Bruno B, McSweeney PA, Pulsipher MA, Chauncey TR, Mielcarek M, Storer BE, Storb R.

Biol Blood Marrow Transplant. 2007 Apr;13(4):423-32. Epub 2007 Feb 1.PMID: 17287157 [PubMed - indexed for MEDLINE]Related articlesFree article

Factors associated with outcomes in allogeneic hematopoietic cell transplantation with nonmyeloablative conditioning after failed myeloablative hematopoietic cell transplantation.

Baron F, Storb R, Storer BE, Maris MB, Niederwieser D, Shizuru JA, Chauncey TR, Bruno B, Forman SJ, McSweeney PA, Maziarz RT, Pulsipher MA, Agura ED, Wade J, Sorror M, Maloney DG, Sandmaier BM.

J Clin Oncol. 2006 Sep 1;24(25):4150-7. Epub 2006 Aug 8.PMID: 16896000 [PubMed - indexed for MEDLINE]Related articles

Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes.

Chaparro RJ, Konigshofer Y, Beilhack GF, Shizuru JA, McDevitt HO, Chien YH.

Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12475-80. Epub 2006 Aug 8. Erratum in: Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15273. PMID: 16895987 [PubMed - indexed for MEDLINE]Related articlesFree article

High-dose carmustine, etoposide, and cyclophosphamide followed by allogeneic hematopoietic cell transplantation for non-Hodgkin lymphoma.

Law LY, Horning SJ, Wong RM, Johnston LJ, Laport GG, Lowsky R, Shizuru JA, Blume KG, Negrin RS, Stockerl-Goldstein KE.

Biol Blood Marrow Transplant. 2006 Jul;12(7):703-11.PMID: 16785059 [PubMed - indexed for MEDLINE]Related articles

Unrelated donor granulocyte colony-stimulating factor-mobilized peripheral blood mononuclear cell transplantation after nonmyeloablative conditioning: the effect of postgrafting mycophenolate mofetil dosing.

Maris MB, Sandmaier BM, Storer BE, Maloney DG, Shizuru JA, Agura E, Kliem C, Pulsipher M, Maziarz RT, McSweeney PA, Wade J, Langston AA, Chauncey TR, Bruno B, Blume KG, Storb R.

Biol Blood Marrow Transplant. 2006 Apr;12(4):454-65.PMID: 16545729 [PubMed - indexed for MEDLINE]Related articles

Treatment for acute myelogenous leukemia by low-dose, total-body, irradiation-based conditioning and hematopoietic cell transplantation from related and unrelated donors.

Hegenbart U, Niederwieser D, Sandmaier BM, Maris MB, Shizuru JA, Greinix H, Cordonnier C, Rio B, Gratwohl A, Lange T, Al-Ali H, Storer B, Maloney D, McSweeney P, Chauncey T, Agura E, Bruno B, Maziarz RT, Petersen F, Storb R.

J Clin Oncol. 2006 Jan 20;24(3):444-53. Epub 2005 Dec 12.PMID: 16344316 [PubMed - indexed for MEDLINE]Related articles

Protective conditioning for acute graft-versus-host disease.

Lowsky R, Takahashi T, Liu YP, Dejbakhsh-Jones S, Grumet FC, Shizuru JA, Laport GG, Stockerl-Goldstein KE, Johnston LJ, Hoppe RT, Bloch DA, Blume KG, Negrin RS, Strober S.

N Engl J Med. 2005 Sep 29;353(13):1321-31. Erratum in: N Engl J Med. 2006 Feb 23;354(8):884. PMID: 16192477 [PubMed - indexed for MEDLINE]Related articlesFree article

Prevention of type 1 diabetes with major histocompatibility complex-compatible and nonmarrow ablative hematopoietic stem cell transplants.

Beilhack GF, Landa RR, Masek MA, Shizuru JA.

Diabetes. 2005 Jun;54(6):1770-9.PMID: 15919799 [PubMed - indexed for MEDLINE]Related articlesFree article

Prognostic relevance of 'early-onset' graft-versus-host disease following non-myeloablative haematopoietic cell transplantation.

Mielcarek M, Burroughs L, Leisenring W, Diaconescu R, Martin PJ, Sandmaier BM, Maloney DG, Maris MB, Chauncey TR, Shizuru JA, Blume KG, Hegenbart U, Niederwieser D, Forman S, Bruno B, Woolfrey A, Storb R.

Br J Haematol. 2005 May;129(3):381-91.PMID: 15842663 [PubMed - indexed for MEDLINE]Related articles

HLA-matched unrelated donor hematopoietic cell transplantation after nonmyeloablative conditioning for patients with chronic myeloid leukemia.

Baron F, Maris MB, Storer BE, Sandmaier BM, Stuart MJ, McSweeney PA, Radich JP, Pulsipher MA, Agura ED, Chauncey TR, Maloney DG, Shizuru JA, Storb R.

Biol Blood Marrow Transplant. 2005 Apr;11(4):272-9.PMID: 15812392 [PubMed - indexed for MEDLINE]Related articles

CD34, CD4, and CD8 cell doses do not influence engraftment, graft-versus-host disease, or survival following myeloablative human leukocyte antigen-identical peripheral blood allografting for hematologic malignancies.

Cao TM, Wong RM, Sheehan K, Laport GG, Stockerl-Goldstein KE, Johnston LJ, Shizuru JA, Negrin RS, Lowsky R.

Exp Hematol. 2005 Mar;33(3):279-85.PMID: 15730851 [PubMed - indexed for MEDLINE]Related articles

Hematopoietic stem and progenitor cells: clinical and preclinical regeneration of the hematolymphoid system.

Shizuru JA, Negrin RS, Weissman IL.

Annu Rev Med. 2005;56:509-38. Review.PMID: 15660525 [PubMed - indexed for MEDLINE]Related articles

Rapamycin (sirolimus) for treatment of chronic graft-versus-host disease.

Johnston LJ, Brown J, Shizuru JA, Stockerl-Goldstein KE, Stuart MJ, Blume KG, Negrin RS, Chao NJ.

Biol Blood Marrow Transplant. 2005 Jan;11(1):47-55.PMID: 15625544 [PubMed - indexed for MEDLINE]Related articles

Cytokines and cytotoxic pathways in engraftment resistance to purified allogeneic hematopoietic stem cells.

Scheffold C, Scheffold YC, Cao TM, Gworek J, Shizuru JA.

Biol Blood Marrow Transplant. 2005 Jan;11(1):1-12.PMID: 15625539 [PubMed - indexed for MEDLINE]Related articles

Engraftment and survival following reduced-intensity allogeneic peripheral blood hematopoietic cell transplantation is affected by CD8+ T-cell dose.

Cao TM, Shizuru JA, Wong RM, Sheehan K, Laport GG, Stockerl-Goldstein KE, Johnston LJ, Stuart MJ, Grumet FC, Negrin RS, Lowsky R.

Blood. 2005 Mar 15;105(6):2300-6. Epub 2004 Nov 30.PMID: 15572597 [PubMed - indexed for MEDLINE]Related articlesFree article

Approaches to transplantation tolerance in humans.

Strober S, Lowsky RJ, Shizuru JA, Scandling JD, Millan MT.

Transplantation. 2004 Mar 27;77(6):932-6. Review.PMID: 15077041 [PubMed - indexed for MEDLINE]Related articles

Variable hematopoietic graft rejection and graft-versus-host disease in MHC-matched strains of mice.

Cao TM, Lo B, Ranheim EA, Grumet FC, Shizuru JA.

Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11571-6. Epub 2003 Sep 22.PMID: 14504392 [PubMed - indexed for MEDLINE]Related articlesFree article

Rituximab as adjuvant to high-dose therapy and autologous hematopoietic cell transplantation for aggressive non-Hodgkin lymphoma.

Horwitz SM, Negrin RS, Blume KG, Breslin S, Stuart MJ, Stockerl-Goldstein KE, Johnston LJ, Wong RM, Shizuru JA, Horning SJ.

Blood. 2004 Feb 1;103(3):777-83. Epub 2003 Aug 7.PMID: 12907446 [PubMed - indexed for MEDLINE]Related articlesFree article

Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalovirus infection after hematopoietic stem cell transplantation.

Arber C, BitMansour A, Sparer TE, Higgins JP, Mocarski ES, Weissman IL, Shizuru JA, Brown JM.

Blood. 2003 Jul 15;102(2):421-8. Epub 2003 Mar 27.PMID: 12663447 [PubMed - indexed for MEDLINE]Related articlesFree article

Biology of hematopoietic stem cells and progenitors: implications for clinical application.

Kondo M, Wagers AJ, Manz MG, Prohaska SS, Scherer DC, Beilhack GF, Shizuru JA, Weissman IL.

Annu Rev Immunol. 2003;21:759-806. Epub 2002 Dec 17. Review.PMID: 12615892 [PubMed - indexed for MEDLINE]Related articles

Reconstitution of NK cell receptor repertoire following HLA-matched hematopoietic cell transplantation.

Shilling HG, McQueen KL, Cheng NW, Shizuru JA, Negrin RS, Parham P.

Blood. 2003 May 1;101(9):3730-40. Epub 2003 Jan 2.PMID: 12511415 [PubMed - indexed for MEDLINE]Related articlesFree article

Purified allogeneic hematopoietic stem cell transplantation blocks diabetes pathogenesis in NOD mice.

Beilhack GF, Scheffold YC, Weissman IL, Taylor C, Jerabek L, Burge MJ, Masek MA, Shizuru JA.

Diabetes. 2003 Jan;52(1):59-68.PMID: 12502494 [PubMed - indexed for MEDLINE]Related articlesFree article

Non-myeloablative transplantation.

Maloney DG, Sandmaier BM, Mackinnon S, Shizuru JA.

Hematology Am Soc Hematol Educ Program. 2002:392-421. Review.PMID: 12446434 [PubMed - indexed for MEDLINE]Related articlesFree article

Related and unrelated nonmyeloablative hematopoietic stem cell transplantation for malignant diseases.

Georges GE, Maris M, Sandmaier BM, Malone DG, Feinstein L, Niederweiser D, Shizuru JA, McSweeney PA, Chauncey TR, Agura E, Little MT, Sahebi F, Hegenbart U, Pulsipher MA, Bruno B, Forman S, Woolfrey AE, Radich JP, Blume KG, Storb R.

Int J Hematol. 2002 Aug;76 Suppl 1:184-9.PMID: 12430851 [PubMed - indexed for MEDLINE]Related articles

Low-dose total body irradiation (TBI) and fludarabine followed by hematopoietic cell transplantation (HCT) from HLA-matched or mismatched unrelated donors and postgrafting immunosuppression with cyclosporine and mycophenolate mofetil (MMF) can induce durable complete chimerism and sustained remissions in patients with hematological diseases.

Niederwieser D, Maris M, Shizuru JA, Petersdorf E, Hegenbart U, Sandmaier BM, Maloney DG, Storer B, Lange T, Chauncey T, Deininger M, Pönisch W, Anasetti C, Woolfrey A, Little MT, Blume KG, McSweeney PA, Storb RF.

Blood. 2003 Feb 15;101(4):1620-9. Epub 2002 Oct 3.PMID: 12393457 [PubMed - indexed for MEDLINE]Related articlesFree article

Mixed chimerism and immunosuppressive drug withdrawal after HLA-mismatched kidney and hematopoietic progenitor transplantation.

Millan MT, Shizuru JA, Hoffmann P, Dejbakhsh-Jones S, Scandling JD, Grumet FC, Tan JC, Salvatierra O, Hoppe RT, Strober S.

Transplantation. 2002 May 15;73(9):1386-91.PMID: 12023614 [PubMed - indexed for MEDLINE]Related articles

Rapid establishment of dendritic cell chimerism in allogeneic hematopoietic cell transplant recipients.

Auffermann-Gretzinger S, Lossos IS, Vayntrub TA, Leong W, Grumet FC, Blume KG, Stockerl-Goldstein KE, Levy R, Shizuru JA.

Blood. 2002 Feb 15;99(4):1442-8.PMID: 11830498 [PubMed - indexed for MEDLINE]Related articlesFree article

Efficacy and toxicity of a CCNU-containing high-dose chemotherapy regimen followed by autologous hematopoietic cell transplantation in relapsed or refractory Hodgkin's disease.

Stuart MJ, Chao NS, Horning SJ, Wong RM, Negrin RS, Johnston LJ, Shizuru JA, Long GD, Blume KG, Stockerl-Goldstein KE.

Biol Blood Marrow Transplant. 2001;7(10):552-60.PMID: 11760087 [PubMed - indexed for MEDLINE]Related articles

Engineering hematopoietic grafts: purified allogeneic hematopoietic stem cells plus expanded CD8+ NK-T cells in the treatment of lymphoma.

Verneris MR, Ito M, Baker J, Arshi A, Negrin RS, Shizuru JA.

Biol Blood Marrow Transplant. 2001;7(10):532-42.PMID: 11760085 [PubMed - indexed for MEDLINE]Related articles

Immunity to infections following hematopoietic cell transplantation.

Brown JM, Weissman IL, Shizuru JA.

Curr Opin Immunol. 2001 Aug;13(4):451-7. Review.PMID: 11498301 [PubMed - indexed for MEDLINE]Related articles

High-dose therapy and autologous hematopoietic-cell transplantation for follicular lymphoma beyond first remission: the Stanford University experience.

Cao TM, Horning S, Negrin RS, Hu WW, Johnston LJ, Taylor TL, Shizuru JA, Hoppe RT, Brown BW, Blume KG, Stockerl-Goldstein KE.

Biol Blood Marrow Transplant. 2001;7(5):294-301.PMID: 11400952 [PubMed - indexed for MEDLINE]Related articles

Hematopoietic cell transplantation in older patients with hematologic malignancies: replacing high-dose cytotoxic therapy with graft-versus-tumor effects.

McSweeney PA, Niederwieser D, Shizuru JA, Sandmaier BM, Molina AJ, Maloney DG, Chauncey TR, Gooley TA, Hegenbart U, Nash RA, Radich J, Wagner JL, Minor S, Appelbaum FR, Bensinger WI, Bryant E, Flowers ME, Georges GE, Grumet FC, Kiem HP, Torok-Storb B, Yu C, Blume KG, Storb RF.

Blood. 2001 Jun 1;97(11):3390-400.PMID: 11369628 [PubMed - indexed for MEDLINE]Related articlesFree article

Expansion of cytolytic CD8(+) natural killer T cells with limited capacity for graft-versus-host disease induction due to interferon gamma production.

Baker J, Verneris MR, Ito M, Shizuru JA, Negrin RS.

Blood. 2001 May 15;97(10):2923-31.PMID: 11342413 [PubMed - indexed for MEDLINE]Related articlesFree article

Toward regenerative medicine.

Lagasse E, Shizuru JA, Uchida N, Tsukamoto A, Weissman IL.

Immunity. 2001 Apr;14(4):425-36. Review. No abstract available. PMID: 11336688 [PubMed - indexed for MEDLINE]Related articles

Pulmonary toxicity syndrome in breast cancer patients undergoing BCNU-containing high-dose chemotherapy and autologous hematopoietic cell transplantation.

Cao TM, Negrin RS, Stockerl-Goldstein KE, Johnston LJ, Shizuru JA, Taylor TL, Rizk NW, Wong RM, Blume KG, Hu WW.

Biol Blood Marrow Transplant. 2000;6(4):387-94.PMID: 10917574 [PubMed - indexed for MEDLINE]Related articles

Purified hematopoietic stem cell grafts induce tolerance to alloantigens and can mediate positive and negative T cell selection.

Shizuru JA, Weissman IL, Kernoff R, Masek M, Scheffold YC.

Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9555-60.PMID: 10920206 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of oral glutamine supplementation during bone marrow transplantation.

Coghlin Dickson TM, Wong RM, offrin RS, Shizuru JA, Johnston LJ, Hu WW, Blume KG, Stockerl-Goldstein KE.

JPEN J Parenter Enteral Nutr. 2000 Mar-Apr;24(2):61-6.PMID: 10772184 [PubMed - indexed for MEDLINE]Related articles