PubMed

A study of passive weight-bearing lower limb exercise effects on local muscles and whole body oxidative metabolism: a comparison with simulated horse riding, bicycle, and walking exercise.

Shimomura K, Murase N, Osada T, Kime R, Anjo M, Esaki K, Shiroishi K, Hamaoka T, Katsumura T.

Dyn Med. 2009 Nov 10;8:4.PMID: 19900292 [PubMed - in process]Related articlesFree article

CKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock.

Isojima Y, Nakajima M, Ukai H, Fujishima H, Yamada RG, Masumoto KH, Kiuchi R, Ishida M, Ukai-Tadenuma M, Minami Y, Kito R, Nakao K, Kishimoto W, Yoo SH, Shimomura K, Takao T, Takano A, Kojima T, Nagai K, Sakaki Y, Takahashi JS, Ueda HR.

Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15744-9. Epub 2009 Sep 2.PMID: 19805222 [PubMed - indexed for MEDLINE]Related articlesFree article

A Proposal of Combined Evaluation of Waist Circumference and BMI for the Diagnosis of Metabolic Syndrome.

Takahashi M, Shimomura K, Proks P, Craig TJ, Negishi M, Akuzawa M, Hayashi R, Shimomura Y, Kobayashi I.

Endocr J. 2009 Sep 5. [Epub ahead of print]PMID: 19734693 [PubMed - as supplied by publisher]Related articlesFree article

Identification of genetic loci involved in diabetes using a rat model of depression.

Solberg Woods LC, Ahmadiyeh N, Baum A, Shimomura K, Li Q, Steiner DF, Turek FW, Takahashi JS, Churchill GA, Redei EE.

Mamm Genome. 2009 Aug;20(8):486-97. Epub 2009 Aug 22.PMID: 19697080 [PubMed - in process]Related articlesFree article

Genetic analysis of daily physical activity using a mouse chromosome substitution strain.

Yang HS, Vitaterna MH, Laposky AD, Shimomura K, Turek FW.

Physiol Genomics. 2009 Sep 9;39(1):47-55. Epub 2009 Jun 30.PMID: 19567786 [PubMed - in process]Related articles

Hemodynamic relationships among upper-abdominal aorta and femoral arteries: basis for measurement of arterial blood flow to abdominal-pelvic organs.

Osada T, Nagata H, Murase N, Shimomura K, Kime R, Shiroishi K, Nakagawa N, Katsumura T.

Med Sci Monit. 2009 Jul;15(7):CR332-40.PMID: 19564822 [PubMed - indexed for MEDLINE]Related articles

Drug-drug interaction between oxycodone and adjuvant analgesics in blood-brain barrier transport and antinociceptive effect.

Nakazawa Y, Okura T, Shimomura K, Terasaki T, Deguchi Y.

J Pharm Sci. 2010 Jan;99(1):467-74.PMID: 19499573 [PubMed - in process]Related articles

Insulin secretion from beta-cells is affected by deletion of nicotinamide nucleotide transhydrogenase.

Shimomura K, Galvanovskis J, Goldsworthy M, Hugill A, Kaizak S, Lee A, Meadows N, Quwailid MM, Rydström J, Teboul L, Ashcroft F, Cox RD.

Methods Enzymol. 2009;457:451-80.PMID: 19426883 [PubMed - indexed for MEDLINE]Related articles

Uncovering the genetic landscape for multiple sleep-wake traits.

Winrow CJ, Williams DL, Kasarskis A, Millstein J, Laposky AD, Yang HS, Mrazek K, Zhou L, Owens JR, Radzicki D, Preuss F, Schadt EE, Shimomura K, Vitaterna MH, Zhang C, Koblan KS, Renger JJ, Turek FW.

PLoS One. 2009;4(4):e5161. Epub 2009 Apr 10.PMID: 19360106 [PubMed - indexed for MEDLINE]Related articlesFree article

An in-frame deletion in Kir6.2 (KCNJ11) causing neonatal diabetes reveals a site of interaction between Kir6.2 and SUR1.

Craig TJ, Shimomura K, Holl RW, Flanagan SE, Ellard S, Ashcroft FM.

J Clin Endocrinol Metab. 2009 Jul;94(7):2551-7. Epub 2009 Apr 7.PMID: 19351728 [PubMed - indexed for MEDLINE]Related articles

Sepsis and gas-forming splenic abscess by Clostridium septicum in a patient with type 2 diabetes.

Imamura M, Shimomura K, Watanabe A, Negishi M, Akuzawa M, Takahashi M, Proks P, Shimomura Y.

J Diabetes Complications. 2009 Mar 12. [Epub ahead of print]PMID: 19285435 [PubMed - as supplied by publisher]Related articles

Mechanism of disopyramide-induced hypoglycaemia in a patient with Type 2 diabetes.

Negishi M, Shimomura K, Proks P, Mori M, Shimomura Y.

Diabet Med. 2009 Jan;26(1):76-8.PMID: 19125764 [PubMed - indexed for MEDLINE]Related articles

Expression of an activating mutation in the gene encoding the KATP channel subunit Kir6.2 in mouse pancreatic beta cells recapitulates neonatal diabetes.

Girard CA, Wunderlich FT, Shimomura K, Collins S, Kaizik S, Proks P, Abdulkader F, Clark A, Ball V, Zubcevic L, Bentley L, Clark R, Church C, Hugill A, Galvanovskis J, Cox R, Rorsman P, Brüning JC, Ashcroft FM.

J Clin Invest. 2009 Jan;119(1):80-90. doi: 10.1172/JCI35772. Epub 2008 Dec 8.PMID: 19065048 [PubMed - indexed for MEDLINE]Related articlesFree article

PVHL is a regulator of glucose metabolism and insulin secretion in pancreatic beta cells.

Zehetner J, Danzer C, Collins S, Eckhardt K, Gerber PA, Ballschmieter P, Galvanovskis J, Shimomura K, Ashcroft FM, Thorens B, Rorsman P, Krek W.

Genes Dev. 2008 Nov 15;22(22):3135-46.PMID: 19056893 [PubMed - indexed for MEDLINE]Related articlesFree article

Investigation of reservoir animals of Leptospira in the northern part of Miyazaki Prefecture.

Koizumi N, Muto M, Yamamoto S, Baba Y, Kudo M, Tamae Y, Shimomura K, Takatori I, Iwakiri A, Ishikawa K, Soma H, Watanabe H.

Jpn J Infect Dis. 2008 Nov;61(6):465-8.PMID: 19050356 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of CHOP messenger RNA expression in the link between oxidative stress and apoptosis.

Ariyama Y, Tanaka Y, Shimizu H, Shimomura K, Okada S, Saito T, Yamada E, Oyadomari S, Mori M, Mori M.

Metabolism. 2008 Dec;57(12):1625-35.PMID: 19013284 [PubMed - indexed for MEDLINE]Related articles

Xenopus oocytes as a heterologous expression system for studying ion channels with the patch-clamp technique.

Tammaro P, Shimomura K, Proks P.

Methods Mol Biol. 2008;491:127-39.PMID: 18998089 [PubMed - indexed for MEDLINE]Related articles

Searching for genes underlying behavior: lessons from circadian rhythms.

Takahashi JS, Shimomura K, Kumar V.

Science. 2008 Nov 7;322(5903):909-12.PMID: 18988844 [PubMed - indexed for MEDLINE]Related articlesFree article

The K(ATP) channel and neonatal diabetes.

Shimomura K.

Endocr J. 2009 Apr;56(2):165-75. Epub 2008 Jun 20. Review.PMID: 18566517 [PubMed - indexed for MEDLINE]Related articlesFree article

Alpha glucosidase inhibitor voglibose can prevent pioglitazone-induced body weight gain in Type 2 diabetic patients.

Negishi M, Shimomura K, Proks P, Shimomura Y, Mori M.

Br J Clin Pharmacol. 2008 Aug;66(2):318-9. Epub 2008 Apr 30. No abstract available. PMID: 18507653 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of RegIV in peritoneal dissemination of gastric cancer and its potential as A novel marker for the detection of peritoneal micrometastasis.

Miyagawa K, Sakakura C, Nakashima S, Yoshikawa T, Fukuda K, Kin S, Nakase Y, Shimomura K, Oue N, Yasui W, Hayasizaki H, Okazaki Y, Yamagishi H, Hagiwara A, Otsuji E.

Anticancer Res. 2008 Mar-Apr;28(2B):1169-79.PMID: 18505053 [PubMed - indexed for MEDLINE]Related articles

Role of the transcription factor sox4 in insulin secretion and impaired glucose tolerance.

Goldsworthy M, Hugill A, Freeman H, Horner E, Shimomura K, Bogani D, Pieles G, Mijat V, Arkell R, Bhattacharya S, Ashcroft FM, Cox RD.

Diabetes. 2008 Aug;57(8):2234-44. Epub 2008 May 13.PMID: 18477811 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene set enrichment in eQTL data identifies novel annotations and pathway regulators.

Wu C, Delano DL, Mitro N, Su SV, Janes J, McClurg P, Batalov S, Welch GL, Zhang J, Orth AP, Walker JR, Glynne RJ, Cooke MP, Takahashi JS, Shimomura K, Kohsaka A, Bass J, Saez E, Wiltshire T, Su AI.

PLoS Genet. 2008 May 9;4(5):e1000070.PMID: 18464898 [PubMed - indexed for MEDLINE]Related articlesFree article

Occurrence of headless sperms in adolescent rat urine.

Shimomura K, Sakurai K, Shimada M, Hagiwara M, Kato M, Furuhama K.

Lab Anim. 2008 Apr;42(2):204-12.PMID: 18435878 [PubMed - indexed for MEDLINE]Related articles

Homofarnesals: female sex attractant pheromone components of the southern cowpea weevil, Callosobruchus chinensis.

Shimomura K, Nojima S, Yajima S, Ohsawa K.

J Chem Ecol. 2008 Apr;34(4):467-77. Epub 2008 Mar 20.PMID: 18351422 [PubMed - indexed for MEDLINE]Related articles

Hydrogen bonding in sodium alanate: a muon spin rotation study.

Kadono R, Shimomura K, Satoh KH, Takeshita S, Koda A, Nishiyama K, Akiba E, Ayabe RM, Kuba M, Jensen CM.

Phys Rev Lett. 2008 Jan 18;100(2):026401. Epub 2008 Jan 15.PMID: 18232891 [PubMed]Related articles

Gene-environment interactions in a mutant mouse kindred with native airway constrictor hyperresponsiveness.

Pinto LH, Eaton E, Chen B, Fleisher J, Shuster D, McCauley J, Kedainis D, Siepka SM, Shimomura K, Song EJ, Husain A, Lakser OJ, Mitchell RW, Dowell ML, Brown M, Camoretti-Mercado B, Naclerio R, Sperling AI, Levin SI, Turek FW, Solway J.

Mamm Genome. 2008 Jan;19(1):2-14. Epub 2008 Jan 1.PMID: 18167028 [PubMed - indexed for MEDLINE]Related articles

Increased ATPase activity produced by mutations at arginine-1380 in nucleotide-binding domain 2 of ABCC8 causes neonatal diabetes.

de Wet H, Rees MG, Shimomura K, Aittoniemi J, Patch AM, Flanagan SE, Ellard S, Hattersley AT, Sansom MS, Ashcroft FM.

Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):18988-92. Epub 2007 Nov 19.PMID: 18025464 [PubMed - indexed for MEDLINE]Related articlesFree article

Arterial blood flow of all abdominal-pelvic organs using Doppler ultrasound: range, variability and physiological impact.

Osada T, Murase N, Kime R, Shiroishi K, Shimomura K, Nagata H, Katsumura T.

Physiol Meas. 2007 Oct;28(10):1303-16. Epub 2007 Sep 28.PMID: 17906396 [PubMed - indexed for MEDLINE]Related articles

Permanent neonatal diabetes caused by dominant, recessive, or compound heterozygous SUR1 mutations with opposite functional effects.

Ellard S, Flanagan SE, Girard CA, Patch AM, Harries LW, Parrish A, Edghill EL, Mackay DJ, Proks P, Shimomura K, Haberland H, Carson DJ, Shield JP, Hattersley AT, Ashcroft FM.

Am J Hum Genet. 2007 Aug;81(2):375-82. Epub 2007 Jun 29.PMID: 17668386 [PubMed - indexed for MEDLINE]Related articlesFree article

A novel mutation causing DEND syndrome: a treatable channelopathy of pancreas and brain.

Shimomura K, Hörster F, de Wet H, Flanagan SE, Ellard S, Hattersley AT, Wolf NI, Ashcroft F, Ebinger F.

Neurology. 2007 Sep 25;69(13):1342-9. Epub 2007 Jul 25.PMID: 17652641 [PubMed - indexed for MEDLINE]Related articles

Interpretation of the mouse electroretinogram.

Pinto LH, Invergo B, Shimomura K, Takahashi JS, Troy JB.

Doc Ophthalmol. 2007 Nov;115(3):127-36. Epub 2007 Jul 17.PMID: 17636411 [PubMed - indexed for MEDLINE]Related articles

Mechanism of action of a sulphonylurea receptor SUR1 mutation (F132L) that causes DEND syndrome.

Proks P, Shimomura K, Craig TJ, Girard CA, Ashcroft FM.

Hum Mol Genet. 2007 Aug 15;16(16):2011-9. Epub 2007 Jun 21.PMID: 17584766 [PubMed - indexed for MEDLINE]Related articlesFree article

PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism.

Medina-Gomez G, Gray SL, Yetukuri L, Shimomura K, Virtue S, Campbell M, Curtis RK, Jimenez-Linan M, Blount M, Yeo GS, Lopez M, Seppänen-Laakso T, Ashcroft FM, Oresic M, Vidal-Puig A.

PLoS Genet. 2007 Apr 27;3(4):e64.PMID: 17465682 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane.

Olofsson CS, Collins S, Bengtsson M, Eliasson L, Salehi A, Shimomura K, Tarasov A, Holm C, Ashcroft F, Rorsman P.

Diabetes. 2007 Jul;56(7):1888-97. Epub 2007 Apr 24.PMID: 17456851 [PubMed - indexed for MEDLINE]Related articlesFree article

Generation, identification and functional characterization of the nob4 mutation of Grm6 in the mouse.

Pinto LH, Vitaterna MH, Shimomura K, Siepka SM, Balannik V, McDearmon EL, Omura C, Lumayag S, Invergo BM, Glawe B, Cantrell DR, Inayat S, Olvera MA, Vessey KA, McCall MA, Maddox D, Morgans CW, Young B, Pletcher MT, Mullins RF, Troy JB, Takahashi JS.

Vis Neurosci. 2007 Jan-Feb;24(1):111-23.PMID: 17430614 [PubMed - indexed for MEDLINE]Related articles

Genomewide association analysis in diverse inbred mice: power and population structure.

McClurg P, Janes J, Wu C, Delano DL, Walker JR, Batalov S, Takahashi JS, Shimomura K, Kohsaka A, Bass J, Wiltshire T, Su AI.

Genetics. 2007 May;176(1):675-83. Epub 2007 Apr 3.PMID: 17409088 [PubMed - indexed for MEDLINE]Related articlesFree article

Contact sex pheromone components of the cowpea weevil, Callosobruchus maculatus.

Nojima S, Shimomura K, Honda H, Yamamoto I, Ohsawa K.

J Chem Ecol. 2007 May;33(5):923-33. Epub 2007 Mar 30.PMID: 17394050 [PubMed - indexed for MEDLINE]Related articles

Effect of peroxisome proliferator-activated receptor alpha ligand fenofibrate on K(v) channels in the insulin-secreting cell line HIT-T15.

Shimomura K, Ikeda M, Ariyama Y, Proks P, Shimomura Y, Mori M, Matsumoto S.

Gen Physiol Biophys. 2006 Dec;25(4):455-60.PMID: 17356236 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic characterization of multidrug resistance in Shigella spp. from Japan.

Ahmed AM, Furuta K, Shimomura K, Kasama Y, Shimamoto T.

J Med Microbiol. 2006 Dec;55(Pt 12):1685-91.PMID: 17108272 [PubMed - indexed for MEDLINE]Related articlesFree article

LjnsRING, a novel RING finger protein, is required for symbiotic interactions between Mesorhizobium loti and Lotus japonicus.

Shimomura K, Nomura M, Tajima S, Kouchi H.

Plant Cell Physiol. 2006 Nov;47(11):1572-81. Epub 2006 Oct 20.PMID: 17056617 [PubMed - indexed for MEDLINE]Related articles

Nicotinamide nucleotide transhydrogenase: a link between insulin secretion, glucose metabolism and oxidative stress.

Freeman H, Shimomura K, Cox RD, Ashcroft FM.

Biochem Soc Trans. 2006 Nov;34(Pt 5):806-10.PMID: 17052203 [PubMed - indexed for MEDLINE]Related articles

Functional analysis of six Kir6.2 (KCNJ11) mutations causing neonatal diabetes.

Girard CA, Shimomura K, Proks P, Absalom N, Castano L, Perez de Nanclares G, Ashcroft FM.

Pflugers Arch. 2006 Dec;453(3):323-32. Epub 2006 Sep 22.PMID: 17021801 [PubMed - indexed for MEDLINE]Related articles

Introduction and evaluation of a newly established holiday work system in the pharmacy ward at Municipal Ikeda Hospital.

Myotoku M, Iwamoto C, Tomida Y, Murayama Y, Irishio K, Nakanishi A, Shimomura K, Ihara Y, Shioishi T, Inui T, Yohiro C, Miyamoto E, Suemura N, Kawaguchi S.

Yakugaku Zasshi. 2006 Oct;126(10):1003-10.PMID: 17016030 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic analysis of the stress-responsive adrenocortical axis.

Solberg LC, Baum AE, Ahmadiyeh N, Shimomura K, Li R, Turek FW, Takahashi JS, Churchill GA, Redei EE.

Physiol Genomics. 2006 Nov 27;27(3):362-9. Epub 2006 Aug 8.PMID: 16895972 [PubMed - indexed for MEDLINE]Related articlesFree article

Characteristics of Atropa belladonna hairy roots cryopreserved by vitrification method.

Touno K, Yoshimatsu K, Shimomura K.

Cryo Letters. 2006 Mar-Apr;27(2):65-72.PMID: 16794738 [PubMed - indexed for MEDLINE]Related articles

Mutations at the same residue (R50) of Kir6.2 (KCNJ11) that cause neonatal diabetes produce different functional effects.

Shimomura K, Girard CA, Proks P, Nazim J, Lippiat JD, Cerutti F, Lorini R, Ellard S, Hattersley AT, Barbetti F, Ashcroft FM.

Diabetes. 2006 Jun;55(6):1705-12. Erratum in: Diabetes. 2007 Mar;56(3):897. Hattersely, Andrew T [corrected to Hattersley, Andrew T]. PMID: 16731833 [PubMed - indexed for MEDLINE]Related articlesFree article

[Efficacy of the combined use of taurine for hyperbilirubinemia caused by UFT therapy after surgery for colonic cancer]

Miyata K, Ikawa O, Izumi H, Shimomura K, Matsumura H, Kakihara N, Katoh Y, Ohgaki M, Iizuka R, Fujii K, Shimotsuma M, Tkenaka A.

Gan To Kagaku Ryoho. 2006 May;33(5):671-3. Japanese. PMID: 16685170 [PubMed - indexed for MEDLINE]Related articles

A chitinase structurally related to the glycoside hydrolase family 48 is indispensable for the hormonally induced diapause termination in a beetle.

Fujita K, Shimomura K, Yamamoto K, Yamashita T, Suzuki K.

Biochem Biophys Res Commun. 2006 Jun 23;345(1):502-7. Epub 2006 May 2.PMID: 16684504 [PubMed - indexed for MEDLINE]Related articles

A comparative study of the incidence of aseptic meningitis in symptomatic natural mumps patients and monovalent mumps vaccine recipients in Japan.

Nagai T, Okafuji T, Miyazaki C, Ito Y, Kamada M, Kumagai T, Yuri K, Sakiyama H, Miyata A, Ihara T, Ochiai H, Shimomura K, Suzuki E, Torigoe S, Igarashi M, Kase T, Okuno Y, Nakayama T.

Vaccine. 2007 Mar 30;25(14):2742-7. Epub 2006 Jan 31.PMID: 16530894 [PubMed - indexed for MEDLINE]Related articles