PubMed

Insulin-mediated Regulation of Decidual Protein Induced by Progesterone (DEPP) in Adipose Tissue and Liver.

Kuroda Y, Kuriyama H, Kihara S, Kishida K, Maeda N, Hibuse T, Nishizawa H, Matsuda M, Funahashi T, Shimomura I.

Horm Metab Res. 2009 Nov 23. [Epub ahead of print]PMID: 19937567 [PubMed - as supplied by publisher]

Accumulation of gene polymorphisms related to plaque disruption and thrombosis is associated with cerebral infarction in subjects with type 2 diabetes.

Katakami N, Takahara M, Kaneto H, Shimizu I, Ohno K, Ishibashi F, Osonoi T, Kashiwagi A, Kawamori R, Shimomura I, Matsuhisa M, Yamasaki Y.

Diabetes Care. 2009 Nov 23. [Epub ahead of print]PMID: 19933990 [PubMed - as supplied by publisher]

Characteristics of sleep-disordered breathing in Japanese patients with type 2 diabetes mellitus.

Kashine S, Kishida K, Funahashi T, Nakagawa Y, Otuki M, Okita K, Iwahashi H, Kihara S, Nakamura T, Matsuzawa Y, Shimomura I.

Metabolism. 2009 Nov 13. [Epub ahead of print]PMID: 19913847 [PubMed - as supplied by publisher]Related articles

Effects of Coffee on Inflammatory Cytokine Gene Expression in Mice Fed High-Fat Diets.

Fukushima Y, Kasuga M, Nakao K, Shimomura I, Matsuzawa Y.

J Agric Food Chem. 2009 Nov 9. [Epub ahead of print]PMID: 19899759 [PubMed - as supplied by publisher]Related articles

Dysregulation of glucose, insulin, triglyceride, blood pressure, and oxidative stress after an oral glucose tolerance test in men with abdominal obesity.

Nakatsuji H, Kishida K, Kitamura T, Nakajima C, Funahashi T, Shimomura I.

Metabolism. 2009 Oct 20. [Epub ahead of print]PMID: 19850310 [PubMed - as supplied by publisher]Related articles

Changes in serum adiponectin concentrations correlate with changes in BMI, waist circumference, and estimated visceral fat area in middle-aged general population.

Okauchi Y, Kishida K, Funahashi T, Noguchi M, Ogawa T, Ryo M, Okita K, Iwahashi H, Imagawa A, Nakamura T, Matsuzawa Y, Shimomura I.

Diabetes Care. 2009 Oct;32(10):e122. No abstract available. PMID: 19793996 [PubMed - in process]Related articles

Pioglitazone Reduces ER Stress in the Liver: Direct Monitoring of in vivo ER Stress Using ER Stress-activated Indicator Transgenic Mice.

Yoshiuchi K, Kaneto H, Matsuoka TA, Kasami R, Kohno K, Iwawaki T, Nakatani Y, Yamasaki Y, Shimomura I, Matsuhisa M.

Endocr J. 2009 Sep 29. [Epub ahead of print]PMID: 19789420 [PubMed - as supplied by publisher]Related articlesFree article

Periadventitial adipose tissue plays a critical role in vascular remodeling.

Takaoka M, Nagata D, Kihara S, Shimomura I, Kimura Y, Tabata Y, Saito Y, Nagai R, Sata M.

Circ Res. 2009 Oct 23;105(9):906-11. Epub 2009 Sep 17.PMID: 19762682 [PubMed - indexed for MEDLINE]Related articles

Glucose enhances collectrin protein expression in insulin-producing MIN6 beta cells.

Saisho K, Fukuhara A, Yasuda T, Sato Y, Fukui K, Iwahashi H, Imagawa A, Hatta M, Shimomura I, Yamagata K.

Biochem Biophys Res Commun. 2009 Nov 6;389(1):133-7. Epub 2009 Aug 26.PMID: 19715677 [PubMed - indexed for MEDLINE]Related articles

Impaired insulin secretion in four Tangier disease patients with ABCA1 mutations.

Koseki M, Matsuyama A, Nakatani K, Inagaki M, Nakaoka H, Kawase R, Yuasa-Kawase M, Tsubakio-Yamamoto K, Masuda D, Sandoval JC, Ohama T, Nakagawa-Toyama Y, Matsuura F, Nishida M, Ishigami M, Hirano K, Sakane N, Kumon Y, Suehiro T, Nakamura T, Shimomura I, Yamashita S.

J Atheroscler Thromb. 2009 Jun;16(3):292-6. Epub 2009 Jun 25.PMID: 19556721 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagonoma diagnosed by arterial stimulation and venous sampling (ASVS).

Okauchi Y, Nammo T, Iwahashi H, Kizu T, Hayashi I, Okita K, Yamagata K, Uno S, Katsube F, Matsuhisa M, Kato K, Aozasa K, Kim T, Osuga K, Nakamori S, Tamaki Y, Funahashi T, Miyagawa J, Shimomura I.

Intern Med. 2009;48(12):1025-30. Epub 2009 Jun 15.PMID: 19525592 [PubMed - indexed for MEDLINE]Related articlesFree article

Blockade of mineralocorticoid receptor reverses adipocyte dysfunction and insulin resistance in obese mice.

Hirata A, Maeda N, Hiuge A, Hibuse T, Fujita K, Okada T, Kihara S, Funahashi T, Shimomura I.

Cardiovasc Res. 2009 Oct 1;84(1):164-72. Epub 2009 Jun 8.PMID: 19505930 [PubMed - indexed for MEDLINE]Related articles

Adiponectin Deficiency Promotes the Production of Inflammatory Mediators While Severely Exacerbating Hepatic Injury in Mice with Polymicrobial Sepsis.

Uji Y, Yamamoto H, Maeda K, Tsuchihashi H, Akabori H, Shimizu T, Endo Y, Shimomura I, Tani T.

J Surg Res. 2009 Jan 14. [Epub ahead of print]PMID: 19481767 [PubMed - as supplied by publisher]Related articles

Adiponectin prevents progression of steatohepatitis in mice by regulating oxidative stress and Kupffer cell phenotype polarization.

Fukushima J, Kamada Y, Matsumoto H, Yoshida Y, Ezaki H, Takemura T, Saji Y, Igura T, Tsutsui S, Kihara S, Funahashi T, Shimomura I, Tamura S, Kiso S, Hayashi N.

Hepatol Res. 2009 Jul;39(7):724-38. Epub 2009 Mar 27.PMID: 19473437 [PubMed - in process]Related articles

Role of copper ion in the pathogenesis of type 2 diabetes.

Tanaka A, Kaneto H, Miyatsuka T, Yamamoto K, Yoshiuchi K, Yamasaki Y, Shimomura I, Matsuoka TA, Matsuhisa M.

Endocr J. 2009 Oct;56(5):699-706. Epub 2009 May 20.PMID: 19461160 [PubMed - indexed for MEDLINE]Related articlesFree article

Visceral obesity and hypoadiponectinemia are significant determinants of hepatic dysfunction: An epidemiologic study of 3827 Japanese subjects.

Kamada Y, Nakamura T, Funahashi T, Ryo M, Nishizawa H, Okauchi Y, Fukushima J, Yoshida Y, Kiso S, Shimomura I, Hayashi N.

J Clin Gastroenterol. 2009 Nov-Dec;43(10):995-1000.PMID: 19407661 [PubMed - in process]Related articles

Adiponectin deficiency is associated with severe polymicrobial sepsis, high inflammatory cytokine levels, and high mortality.

Uji Y, Yamamoto H, Tsuchihashi H, Maeda K, Funahashi T, Shimomura I, Shimizu T, Endo Y, Tani T.

Surgery. 2009 May;145(5):550-7. Epub 2009 Mar 21.PMID: 19375615 [PubMed - indexed for MEDLINE]Related articles

Dysregulated glutathione metabolism links to impaired insulin action in adipocytes.

Kobayashi H, Matsuda M, Fukuhara A, Komuro R, Shimomura I.

Am J Physiol Endocrinol Metab. 2009 Jun;296(6):E1326-34. Epub 2009 Apr 14.PMID: 19366877 [PubMed - indexed for MEDLINE]Related articles

The heart requires glycerol as an energy substrate through aquaporin 7, a glycerol facilitator.

Hibuse T, Maeda N, Nakatsuji H, Tochino Y, Fujita K, Kihara S, Funahashi T, Shimomura I.

Cardiovasc Res. 2009 Jul 1;83(1):34-41. Epub 2009 Mar 18.PMID: 19297367 [PubMed - indexed for MEDLINE]Related articles

Adiponectin ameliorates hypoxia-induced pulmonary arterial remodeling.

Nakagawa Y, Kishida K, Kihara S, Funahashi T, Shimomura I.

Biochem Biophys Res Commun. 2009 Apr 24;382(1):183-8. Epub 2009 Mar 9.PMID: 19275879 [PubMed - indexed for MEDLINE]Related articles

Competitive binding of musclin to natriuretic peptide receptor 3 with atrial natriuretic peptide.

Kita S, Nishizawa H, Okuno Y, Tanaka M, Yasui A, Matsuda M, Yamada Y, Shimomura I.

J Endocrinol. 2009 May;201(2):287-95. Epub 2009 Feb 25.PMID: 19244276 [PubMed - indexed for MEDLINE]Related articles

Obesity causes a shift in metabolic flow of gangliosides in adipose tissues.

Tanabe A, Matsuda M, Fukuhara A, Miyata Y, Komuro R, Shimomura I, Tojo H.

Biochem Biophys Res Commun. 2009 Feb 6;379(2):547-52. Epub 2008 Dec 29.PMID: 19116132 [PubMed - indexed for MEDLINE]Related articles

RhoA induces expression of inflammatory cytokine in adipocytes.

Nakayama Y, Komuro R, Yamamoto A, Miyata Y, Tanaka M, Matsuda M, Fukuhara A, Shimomura I.

Biochem Biophys Res Commun. 2009 Feb 6;379(2):288-92. Epub 2008 Dec 25.PMID: 19101507 [PubMed - indexed for MEDLINE]Related articles

A novel mouse model for type 2 diabetes and non-alcoholic fatty liver disease: spontaneous amelioration of diabetes by augmented beta cell mass.

Oze-Fukai A, Fujisawa T, Sugimoto K, Nojima K, Shindo N, Shimoyoshi S, Yoshikawa Y, Sato Y, Shimomura I, Ikegami H, Rakugi H.

Endocr J. 2009 Apr;56(2):227-34. Epub 2008 Dec 17.PMID: 19088402 [PubMed - indexed for MEDLINE]Related articlesFree article

Serum adiponectin concentrations correlate with severity of rheumatoid arthritis evaluated by extent of joint destruction.

Ebina K, Fukuhara A, Ando W, Hirao M, Koga T, Oshima K, Matsuda M, Maeda K, Nakamura T, Ochi T, Shimomura I, Yoshikawa H, Hashimoto J.

Clin Rheumatol. 2009 Apr;28(4):445-51. Epub 2008 Dec 16.PMID: 19085030 [PubMed - indexed for MEDLINE]Related articles

Adiponectin deficiency enhances colorectal carcinogenesis and liver tumor formation induced by azoxymethane in mice.

Nishihara T, Baba M, Matsuda M, Inoue M, Nishizawa Y, Fukuhara A, Araki H, Kihara S, Funahashi T, Tamura S, Hayashi N, Iishi H, Shimomura I.

World J Gastroenterol. 2008 Nov 14;14(42):6473-80.PMID: 19030198 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenovirus-mediated gene transfer of adiponectin reduces the severity of collagen-induced arthritis in mice.

Ebina K, Oshima K, Matsuda M, Fukuhara A, Maeda K, Kihara S, Hashimoto J, Ochi T, Banda NK, Yoshikawa H, Shimomura I.

Biochem Biophys Res Commun. 2009 Jan 9;378(2):186-91. Epub 2008 Nov 21.PMID: 19026984 [PubMed - indexed for MEDLINE]Related articles

Delayed liver regeneration after partial hepatectomy in adiponectin knockout mice.

Ezaki H, Yoshida Y, Saji Y, Takemura T, Fukushima J, Matsumoto H, Kamada Y, Wada A, Igura T, Kihara S, Funahashi T, Shimomura I, Tamura S, Kiso S, Hayashi N.

Biochem Biophys Res Commun. 2009 Jan 2;378(1):68-72. Epub 2008 Nov 12.PMID: 19013135 [PubMed - indexed for MEDLINE]Related articles

Identification of a novel distal enhancer in human adiponectin gene.

Segawa K, Matsuda M, Fukuhara A, Morita K, Okuno Y, Komuro R, Shimomura I.

J Endocrinol. 2009 Jan;200(1):107-16. Epub 2008 Oct 17.PMID: 18931025 [PubMed - indexed for MEDLINE]Related articles

Metabolic impact of adipose and hepatic glycerol channels aquaporin 7 and aquaporin 9.

Maeda N, Funahashi T, Shimomura I.

Nat Clin Pract Endocrinol Metab. 2008 Nov;4(11):627-34. Epub 2008 Oct 14. Review.PMID: 18852723 [PubMed - indexed for MEDLINE]Related articles

Chylomicron remnants are increased in the postprandial state in CD36 deficiency.

Masuda D, Hirano K, Oku H, Sandoval JC, Kawase R, Yuasa-Kawase M, Yamashita Y, Takada M, Tsubakio-Yamamoto K, Tochino Y, Koseki M, Matsuura F, Nishida M, Kawamoto T, Ishigami M, Hori M, Shimomura I, Yamashita S.

J Lipid Res. 2009 May;50(5):999-1011. Epub 2008 Aug 27.PMID: 18753675 [PubMed - indexed for MEDLINE]Related articles

Adiponectin prevents atherosclerosis by increasing cholesterol efflux from macrophages.

Tsubakio-Yamamoto K, Matsuura F, Koseki M, Oku H, Sandoval JC, Inagaki M, Nakatani K, Nakaoka H, Kawase R, Yuasa-Kawase M, Masuda D, Ohama T, Maeda N, Nakagawa-Toyama Y, Ishigami M, Nishida M, Kihara S, Shimomura I, Yamashita S.

Biochem Biophys Res Commun. 2008 Oct 24;375(3):390-4. Epub 2008 Aug 12.PMID: 18703020 [PubMed - indexed for MEDLINE]Related articles

A common P2 promoter polymorphism of the hepatocyte nuclear factor-4alpha gene is associated with insulin secretion in non-obese Japanese with type 2 diabetes.

Tokunaga A, Horikawa Y, Fukuda-Akita E, Okita K, Iwahashi H, Shimomura I, Takeda J, Yamagata K.

Endocr J. 2008 Dec;55(6):999-1004. Epub 2008 Jul 24.PMID: 18654034 [PubMed - indexed for MEDLINE]Related articlesFree article

PGC-1alpha Gly482Ser polymorphism is associated with the plasma adiponectin level in type 2 diabetic men.

Okauchi Y, Iwahashi H, Okita K, Yuan M, Matsuda M, Tanaka T, Miyagawa J, Funahashi T, Horikawa Y, Shimomura I, Yamagata K.

Endocr J. 2008 Dec;55(6):991-7. Epub 2008 Jul 10.PMID: 18614852 [PubMed - indexed for MEDLINE]Related articlesFree article

Relationship between the serum uric acid level, visceral fat accumulation and serum adiponectin concentration in Japanese men.

Tamba S, Nishizawa H, Funahashi T, Okauchi Y, Ogawa T, Noguchi M, Fujita K, Ryo M, Kihara S, Iwahashi H, Yamagata K, Nakamura T, Shimomura I, Matsuzawa Y.

Intern Med. 2008;47(13):1175-80. Epub 2008 Jul 1.PMID: 18591837 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin plays a protective role in caerulein-induced acute pancreatitis in mice fed a high-fat diet.

Araki H, Nishihara T, Matsuda M, Fukuhara A, Kihara S, Funahashi T, Kataoka TR, Kamada Y, Kiyohara T, Tamura S, Hayashi N, Shimomura I.

Gut. 2008 Oct;57(10):1431-40. Epub 2008 Jun 25.PMID: 18579666 [PubMed - indexed for MEDLINE]Related articles

[Role of adipocytokine in bone metabolism]

Ebina K, Fukuhara A, Shimomura I.

Clin Calcium. 2008 May;18(5):623-30. Review. Japanese. PMID: 18445880 [PubMed - indexed for MEDLINE]Related articles

Evaluation of a homogeneous assay for measuring LDL-cholesterol in hyperlipidemic serum specimens.

Yamashita S, Nakamura M, Koizumi H, Oku H, C Sandoval J, Tsubakio-Yamamoto K, Kawase M, Masuda D, Koseki M, Matsuura F, Shimomura I, Nishida M, Ishigami M.

J Atheroscler Thromb. 2008 Apr;15(2):82-6. Epub 2008 Apr 3.PMID: 18385537 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of statins on adipose tissue inflammation: their inhibitory effect on MyD88-independent IRF3/IFN-beta pathway in macrophages.

Abe M, Matsuda M, Kobayashi H, Miyata Y, Nakayama Y, Komuro R, Fukuhara A, Shimomura I.

Arterioscler Thromb Vasc Biol. 2008 May;28(5):871-7. Epub 2008 Mar 6.PMID: 18323514 [PubMed - indexed for MEDLINE]Related articlesFree article

Adiponectin protects against angiotensin II-induced cardiac fibrosis through activation of PPAR-alpha.

Fujita K, Maeda N, Sonoda M, Ohashi K, Hibuse T, Nishizawa H, Nishida M, Hiuge A, Kurata A, Kihara S, Shimomura I, Funahashi T.

Arterioscler Thromb Vasc Biol. 2008 May;28(5):863-70. Epub 2008 Feb 28.PMID: 18309113 [PubMed - indexed for MEDLINE]Related articlesFree article

The -1535 promoter variant of the visfatin gene is associated with serum triglyceride and HDL-cholesterol levels in Japanese subjects.

Tokunaga A, Miura A, Okauchi Y, Segawa K, Fukuhara A, Okita K, Takahashi M, Funahashi T, Miyagawa J, Shimomura I, Yamagata K.

Endocr J. 2008 Mar;55(1):205-12. Epub 2008 Feb 13.PMID: 18270432 [PubMed - indexed for MEDLINE]Related articlesFree article

The tetraspanin CD9 modulates epidermal growth factor receptor signaling in cancer cells.

Murayama Y, Shinomura Y, Oritani K, Miyagawa J, Yoshida H, Nishida M, Katsube F, Shiraga M, Miyazaki T, Nakamoto T, Tsutsui S, Tamura S, Higashiyama S, Shimomura I, Hayashi N.

J Cell Physiol. 2008 Jul;216(1):135-43.PMID: 18247373 [PubMed - indexed for MEDLINE]Related articles

Prognostic value of adiponectin for cardiovascular disease and mortality.

Dekker JM, Funahashi T, Nijpels G, Pilz S, Stehouwer CD, Snijder MB, Bouter LM, Matsuzawa Y, Shimomura I, Heine RJ.

J Clin Endocrinol Metab. 2008 Apr;93(4):1489-96. Epub 2008 Jan 22.PMID: 18211973 [PubMed - indexed for MEDLINE]Related articlesFree article

Nocturnal reduction in circulating adiponectin concentrations related to hypoxic stress in severe obstructive sleep apnea-hypopnea syndrome.

Nakagawa Y, Kishida K, Kihara S, Sonoda M, Hirata A, Yasui A, Nishizawa H, Nakamura T, Yoshida R, Shimomura I, Funahashi T.

Am J Physiol Endocrinol Metab. 2008 Apr;294(4):E778-84. Epub 2008 Jan 15.PMID: 18198351 [PubMed - indexed for MEDLINE]Related articlesFree article

URB is abundantly expressed in adipose tissue and dysregulated in obesity.

Okada T, Nishizawa H, Kurata A, Tamba S, Sonoda M, Yasui A, Kuroda Y, Hibuse T, Maeda N, Kihara S, Hadama T, Tobita K, Akamatsu S, Maeda K, Shimomura I, Funahashi T.

Biochem Biophys Res Commun. 2008 Mar 7;367(2):370-6. Epub 2008 Jan 4.PMID: 18178152 [PubMed - indexed for MEDLINE]Related articles

Clinical significance of high-molecular weight form of adiponectin in male patients with coronary artery disease.

Komura N, Kihara S, Sonoda M, Kumada M, Fujita K, Hiuge A, Okada T, Nakagawa Y, Tamba S, Kuroda Y, Hayashi N, Sumitsuji S, Kawamoto T, Matsumoto S, Ouchi N, Arita Y, Okamoto Y, Shimomura I, Funahashi T, Matsuzawa Y; Osaka CAD Group.

Circ J. 2008 Jan;72(1):23-8. Erratum in: Circ J. 2008 Mar;72(3):508. PMID: 18159094 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipose expression of catalase is regulated via a novel remote PPARgamma-responsive region.

Okuno Y, Matsuda M, Kobayashi H, Morita K, Suzuki E, Fukuhara A, Komuro R, Shimabukuro M, Shimomura I.

Biochem Biophys Res Commun. 2008 Feb 15;366(3):698-704. Epub 2007 Dec 10.PMID: 18073138 [PubMed - indexed for MEDLINE]Related articles

Insulin induces chaperone and CHOP gene expressions in adipocytes.

Miyata Y, Fukuhara A, Matsuda M, Komuro R, Shimomura I.

Biochem Biophys Res Commun. 2008 Jan 25;365(4):826-32. Epub 2007 Nov 21.PMID: 18035047 [PubMed - indexed for MEDLINE]Related articles

Impaired early insulin secretion in Japanese type 2 diabetes with metabolic syndrome.

Fukuda-Akita E, Okita K, Okauchi Y, Ryo M, Nakamura T, Funahashi T, Iwahashi H, Shimomura I, Miyagawa J, Yamagata K.

Diabetes Res Clin Pract. 2008 Mar;79(3):482-9. Epub 2007 Nov 14.PMID: 18006169 [PubMed - indexed for MEDLINE]Related articles

Expression of HNF-4alpha (MODY1), HNF-1beta (MODY5), and HNF-1alpha (MODY3) proteins in the developing mouse pancreas.

Nammo T, Yamagata K, Tanaka T, Kodama T, Sladek FM, Fukui K, Katsube F, Sato Y, Miyagawa J, Shimomura I.

Gene Expr Patterns. 2008 Jan;8(2):96-106. Epub 2007 Oct 9.PMID: 17996499 [PubMed - indexed for MEDLINE]Related articles