PubMed

Epithelial Mesenchymal Transition in Human Ocular Chronic Graft-Versus-Host Disease.

Ogawa Y, Shimmura S, Kawakita T, Yoshida S, Kawakami Y, Tsubota K.

Am J Pathol. 2009 Nov 5. [Epub ahead of print]PMID: 19893038 [PubMed - as supplied by publisher]Related articles

Prospective identification, isolation, and systemic transplantation of multipotent mesenchymal stem cells in murine bone marrow.

Morikawa S, Mabuchi Y, Kubota Y, Nagai Y, Niibe K, Hiratsu E, Suzuki S, Miyauchi-Hara C, Nagoshi N, Sunabori T, Shimmura S, Miyawaki A, Nakagawa T, Suda T, Okano H, Matsuzaki Y.

J Exp Med. 2009 Oct 26;206(11):2483-96. Epub 2009 Oct 19.PMID: 19841085 [PubMed - indexed for MEDLINE]Related articles

Characteristics of traumatic globe rupture after keratoplasty.

Kawashima M, Kawakita T, Shimmura S, Tsubota K, Shimazaki J.

Ophthalmology. 2009 Nov;116(11):2072-6. Epub 2009 Sep 19.PMID: 19766315 [PubMed - indexed for MEDLINE]Related articles

Nucleostemin as a possible progenitor marker of corneal epithelial cells.

Kawashima M, Kawakita T, Yoshida S, Shimmura S, Tsubota K.

Mol Vis. 2009 Jun 10;15:1162-8.PMID: 19521549 [PubMed - indexed for MEDLINE]Related articlesFree article

N-cadherin in the maintenance of human corneal limbal epithelial progenitor cells in vitro.

Higa K, Shimmura S, Miyashita H, Kato N, Ogawa Y, Kawakita T, Shimazaki J, Tsubota K.

Invest Ophthalmol Vis Sci. 2009 Oct;50(10):4640-5. Epub 2009 May 6.PMID: 19420343 [PubMed - indexed for MEDLINE]Related articles

Greater growth potential of p63-positive epithelial cell clusters maintained in human limbal epithelial sheets.

Kawakita T, Shimmura S, Higa K, Espana EM, He H, Shimazaki J, Tsubota K, Tseng SC.

Invest Ophthalmol Vis Sci. 2009 Oct;50(10):4611-7. Epub 2009 Mar 25.PMID: 19324845 [PubMed - indexed for MEDLINE]Related articles

Effect of anterior and posterior corneal surface irregularity on vision after Descemet-stripping endothelial keratoplasty.

Yamaguchi T, Negishi K, Yamaguchi K, Murat D, Uchino Y, Shimmura S, Tsubota K.

J Cataract Refract Surg. 2009 Apr;35(4):688-94.PMID: 19304090 [PubMed - indexed for MEDLINE]Related articles

Long-term culture and growth kinetics of murine corneal epithelial cells expanded from single corneas.

Ma X, Shimmura S, Miyashita H, Yoshida S, Kubota M, Kawakita T, Tsubota K.

Invest Ophthalmol Vis Sci. 2009 Jun;50(6):2716-21. Epub 2009 Feb 14.PMID: 19218612 [PubMed - indexed for MEDLINE]Related articles

End-stage glaucoma in Stevens-Johnson syndrome.

Yuki K, Shimmura S, Shiba D, Tsubota K.

Jpn J Ophthalmol. 2009 Jan;53(1):68-70. Epub 2009 Jan 30. No abstract available. PMID: 19184318 [PubMed - indexed for MEDLINE]Related articles

Development of mesenchymal stem cells partially originate from the neural crest.

Morikawa S, Mabuchi Y, Niibe K, Suzuki S, Nagoshi N, Sunabori T, Shimmura S, Nagai Y, Nakagawa T, Okano H, Matsuzaki Y.

Biochem Biophys Res Commun. 2009 Feb 20;379(4):1114-9. Epub 2009 Jan 20.PMID: 19161980 [PubMed - indexed for MEDLINE]Related articles

The use of human mesenchymal stem cell-derived feeder cells for the cultivation of transplantable epithelial sheets.

Omoto M, Miyashita H, Shimmura S, Higa K, Kawakita T, Yoshida S, McGrogan M, Shimazaki J, Tsubota K.

Invest Ophthalmol Vis Sci. 2009 May;50(5):2109-15. Epub 2009 Jan 10.PMID: 19136703 [PubMed - indexed for MEDLINE]Related articles

Trabeculotomy for the treatment of glaucoma after Descemet stripping endothelial keratoplasty.

Yuki K, Shimmura S, Shiba D, Tsubota K.

Br J Ophthalmol. 2008 Sep;92(9):1299-300. No abstract available. PMID: 18723751 [PubMed - indexed for MEDLINE]Related articles

Japan Ministry of Health study on prevalence of dry eye disease among Japanese high school students.

Uchino M, Dogru M, Uchino Y, Fukagawa K, Shimmura S, Takebayashi T, Schaumberg DA, Tsubota K.

Am J Ophthalmol. 2008 Dec;146(6):925-9.e2. Epub 2008 Aug 23.PMID: 18723141 [PubMed - indexed for MEDLINE]Related articles

Prevalence of dry eye disease among Japanese visual display terminal users.

Uchino M, Schaumberg DA, Dogru M, Uchino Y, Fukagawa K, Shimmura S, Satoh T, Takebayashi T, Tsubota K.

Ophthalmology. 2008 Nov;115(11):1982-8. Epub 2008 Aug 16.PMID: 18708259 [PubMed - indexed for MEDLINE]Related articles

Surgical treatment of limbal stem cell deficiency: are we really transplanting stem cells?

Shimmura S, Tsubota K.

Am J Ophthalmol. 2008 Aug;146(2):154-5. No abstract available. PMID: 18656582 [PubMed - indexed for MEDLINE]Related articles

Roles of STAT3/SOCS3 pathway in regulating the visual function and ubiquitin-proteasome-dependent degradation of rhodopsin during retinal inflammation.

Ozawa Y, Nakao K, Kurihara T, Shimazaki T, Shimmura S, Ishida S, Yoshimura A, Tsubota K, Okano H.

J Biol Chem. 2008 Sep 5;283(36):24561-70. Epub 2008 Jul 9.PMID: 18614536 [PubMed - indexed for MEDLINE]Related articlesFree article

Isolation of oral epithelial progenitors using collagen IV.

Igarashi T, Shimmura S, Yoshida S, Tonogi M, Shinozaki N, Yamane GY.

Oral Dis. 2008 Jul;14(5):413-8.PMID: 18466216 [PubMed - indexed for MEDLINE]Related articles

A novel NIH/3T3 duplex feeder system to engineer corneal epithelial sheets with enhanced cytokeratin 15-positive progenitor populations.

Miyashita H, Shimmura S, Higa K, Yoshida S, Kawakita T, Shimazaki J, Tsubota K.

Tissue Eng Part A. 2008 Jul;14(7):1275-82.PMID: 18433313 [PubMed - indexed for MEDLINE]Related articles

Stratified epithelial sheets engineered from a single adult murine corneal/limbal progenitor cell.

Kawakita T, Shimmura S, Hornia A, Higa K, Tseng SC.

J Cell Mol Med. 2008 Aug;12(4):1303-16. Epub 2008 Mar 4.PMID: 18318692 [PubMed - indexed for MEDLINE]Related articles

Suppression of alkali burn-induced corneal neovascularization by dendritic cell vaccination targeting VEGF receptor 2.

Mochimaru H, Usui T, Yaguchi T, Nagahama Y, Hasegawa G, Usui Y, Shimmura S, Tsubota K, Amano S, Kawakami Y, Ishida S.

Invest Ophthalmol Vis Sci. 2008 May;49(5):2172-7. Epub 2008 Feb 8.PMID: 18263815 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunohistochemistry and electron microscopy of retrocorneal scrolls in syphilitic interstitial keratitis.

Dogru M, Kato N, Matsumoto Y, Tanaka Y, Akabane N, Shimmura S, Tsubota K, Shimazaki J.

Curr Eye Res. 2007 Oct;32(10):863-70.PMID: 17963106 [PubMed - indexed for MEDLINE]Related articles

Postkeratoplasty atopic sclerokeratitis in keratoconus patients.

Tomita M, Shimmura S, Tsubota K, Shimazaki J.

Ophthalmology. 2008 May;115(5):851-6. Epub 2007 Sep 20.PMID: 17884169 [PubMed - indexed for MEDLINE]Related articles

The application of in vivo confocal scanning laser microscopy in the management of Acanthamoeba keratitis.

Matsumoto Y, Dogru M, Sato EA, Katono Y, Uchino Y, Shimmura S, Tsubota K.

Mol Vis. 2007 Jul 25;13:1319-26.PMID: 17679934 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoxia enhances the expansion of human limbal epithelial progenitor cells in vitro.

Miyashita H, Higa K, Kato N, Kawakita T, Yoshida S, Tsubota K, Shimmura S.

Invest Ophthalmol Vis Sci. 2007 Aug;48(8):3586-93.PMID: 17652727 [PubMed - indexed for MEDLINE]Related articlesFree article

[Deep lamellar keratoplasty in severe ocular surface disease]

Shimmura S, Higa A, Omoto M, Shimazaki J, Tsubota K.

Nippon Ganka Gakkai Zasshi. 2007 May;111(5):391-6. Japanese. PMID: 17536498 [PubMed - indexed for MEDLINE]Related articles

Factors influencing outcomes in cultivated limbal epithelial transplantation for chronic cicatricial ocular surface disorders.

Shimazaki J, Higa K, Morito F, Dogru M, Kawakita T, Satake Y, Shimmura S, Tsubota K.

Am J Ophthalmol. 2007 Jun;143(6):945-53. Epub 2007 Apr 24.PMID: 17459317 [PubMed - indexed for MEDLINE]Related articles

Beta-catenin activation and epithelial-mesenchymal transition in the pathogenesis of pterygium.

Kato N, Shimmura S, Kawakita T, Miyashita H, Ogawa Y, Yoshida S, Higa K, Okano H, Tsubota K.

Invest Ophthalmol Vis Sci. 2007 Apr;48(4):1511-7.PMID: 17389479 [PubMed - indexed for MEDLINE]Related articlesFree article

Albumin rescues ocular epithelial cells from cell death in dry eye.

Higuchi A, Ueno R, Shimmura S, Suematsu M, Dogru M, Tsubota K.

Curr Eye Res. 2007 Feb;32(2):83-8.PMID: 17364740 [PubMed - indexed for MEDLINE]Related articles

Impact of the descemet membrane perforation on surgical outcomes after deep lamellar keratoplasty.

Den S, Shimmura S, Tsubota K, Shimazaki J.

Am J Ophthalmol. 2007 May;143(5):750-4. Epub 2007 Mar 23.PMID: 17362863 [PubMed - indexed for MEDLINE]Related articles

Role of heat shock protein 47, a collagen-binding chaperone, in lacrimal gland pathology in patients with cGVHD.

Ogawa Y, Razzaque MS, Kameyama K, Hasegawa G, Shimmura S, Kawai M, Okamoto S, Ikeda Y, Tsubota K, Kawakami Y, Kuwana M.

Invest Ophthalmol Vis Sci. 2007 Mar;48(3):1079-86.PMID: 17325149 [PubMed - indexed for MEDLINE]Related articlesFree article

Proliferation and differentiation of transplantable rabbit epithelial sheets engineered with or without an amniotic membrane carrier.

Higa K, Shimmura S, Kato N, Kawakita T, Miyashita H, Itabashi Y, Fukuda K, Shimazaki J, Tsubota K.

Invest Ophthalmol Vis Sci. 2007 Feb;48(2):597-604.PMID: 17251455 [PubMed - indexed for MEDLINE]Related articlesFree article

SOCS3 is required to temporally fine-tune photoreceptor cell differentiation.

Ozawa Y, Nakao K, Shimazaki T, Shimmura S, Kurihara T, Ishida S, Yoshimura A, Tsubota K, Okano H.

Dev Biol. 2007 Mar 15;303(2):591-600. Epub 2006 Dec 1.PMID: 17198696 [PubMed - indexed for MEDLINE]Related articles

Ocular surface epithelial cells up-regulate HLA-G when expanded in vitro on amniotic membrane substrates.

Higa K, Shimmura S, Shimazaki J, Tsubota K.

Cornea. 2006 Jul;25(6):715-21.PMID: 17077667 [PubMed - indexed for MEDLINE]Related articles

Association between meibomian gland changes and aging, sex, or tear function.

Den S, Shimizu K, Ikeda T, Tsubota K, Shimmura S, Shimazaki J.

Cornea. 2006 Jul;25(6):651-5.PMID: 17077655 [PubMed - indexed for MEDLINE]Related articles

Cytokeratin 15 can be used to identify the limbal phenotype in normal and diseased ocular surfaces.

Yoshida S, Shimmura S, Kawakita T, Miyashita H, Den S, Shimazaki J, Tsubota K.

Invest Ophthalmol Vis Sci. 2006 Nov;47(11):4780-6.PMID: 17065488 [PubMed - indexed for MEDLINE]Related articlesFree article

Dacryoadenitis associated with Acanthamoeba keratitis.

Tomita M, Shimmura S, Tsubota K, Shimazaki J.

Arch Ophthalmol. 2006 Sep;124(9):1239-42.PMID: 16966617 [PubMed - indexed for MEDLINE]Related articlesFree article

Amniotic membrane immobilized poly(vinyl alcohol) hybrid polymer as an artificial cornea scaffold that supports a stratified and differentiated corneal epithelium.

Uchino Y, Shimmura S, Miyashita H, Taguchi T, Kobayashi H, Shimazaki J, Tanaka J, Tsubota K.

J Biomed Mater Res B Appl Biomater. 2007 Apr;81(1):201-6.PMID: 16924609 [PubMed - indexed for MEDLINE]Related articles

Deep anterior lamellar keratoplasty.

Shimmura S, Tsubota K.

Curr Opin Ophthalmol. 2006 Aug;17(4):349-55. Review.PMID: 16900026 [PubMed - indexed for MEDLINE]Related articles

Isolation of multipotent neural crest-derived stem cells from the adult mouse cornea.

Yoshida S, Shimmura S, Nagoshi N, Fukuda K, Matsuzaki Y, Okano H, Tsubota K.

Stem Cells. 2006 Dec;24(12):2714-22. Epub 2006 Aug 3.PMID: 16888282 [PubMed - indexed for MEDLINE]Related articlesFree article

Comparison of deep lamellar keratoplasty and penetrating keratoplasty for lattice and macular corneal dystrophies.

Kawashima M, Kawakita T, Den S, Shimmura S, Tsubota K, Shimazaki J.

Am J Ophthalmol. 2006 Aug;142(2):304-9.PMID: 16876513 [PubMed - indexed for MEDLINE]Related articles

Disseminated keratoconjunctival epitheliopathy in a patient with systemic lupus erythematosus.

Den S, Dogru M, Kato N, Tanaka Y, Shimmura S, Shimazaki J.

Br J Ophthalmol. 2006 Aug;90(8):1068-70. No abstract available. PMID: 16854840 [PubMed - indexed for MEDLINE]Related articlesFree article

Proteomic analysis of soluble factors secreted by limbal fibroblasts.

Shimmura S, Miyashita H, Higa K, Yoshida S, Shimazaki J, Tsubota K.

Mol Vis. 2006 May 11;12:478-84.PMID: 16710172 [PubMed - indexed for MEDLINE]Related articlesFree article

Accessory cell populations in the cornea.

Shimmura S, Kawakita T.

Ocul Surf. 2006 Apr;4(2):74-80. Review.PMID: 16681078 [PubMed - indexed for MEDLINE]Related articles

Changes observed in keratolimbal allograft.

Maruyama-Hosoi F, Shimazaki J, Shimmura S, Tsubota K.

Cornea. 2006 May;25(4):377-82.PMID: 16670472 [PubMed - indexed for MEDLINE]Related articles

Long-standing bullous keratopathy is associated with peripheral conjunctivalization and limbal deficiency.

Uchino Y, Goto E, Takano Y, Dogru M, Shinozaki N, Shimmura S, Yagi Y, Tsubota K, Shimazaki J.

Ophthalmology. 2006 Jul;113(7):1098-101. Epub 2006 May 2.PMID: 16647124 [PubMed - indexed for MEDLINE]Related articles

Microkeratome assisted deep lamellar keratoprosthesis.

Shimmura S, Miyashita H, Uchino Y, Taguchi T, Kobayashi H, Shimazaki J, Tanaka J, Tsubota K.

Br J Ophthalmol. 2006 Jul;90(7):826-9. Epub 2006 Apr 5.PMID: 16597665 [PubMed - indexed for MEDLINE]Related articlesFree article

Elucidation of apoptosis induced by serum deprivation in cultured conjunctival epithelial cells.

Higuchi A, Shimmura S, Takeuchi T, Suematsu M, Tsubota K.

Br J Ophthalmol. 2006 Jun;90(6):760-4. Epub 2006 Mar 10.PMID: 16531423 [PubMed - indexed for MEDLINE]Related articlesFree article

Deep lamellar keratoplasty.

Shimmura S, Tsubota K.

Am J Ophthalmol. 2006 Feb;141(2):352-3. No abstract available. PMID: 16458693 [PubMed - indexed for MEDLINE]Related articles

Ocular surface reconstruction for thermal burns caused by fireworks.

Shimazaki J, Konomi K, Shimmura S, Tsubota K.

Cornea. 2006 Feb;25(2):139-45.PMID: 16371771 [PubMed - indexed for MEDLINE]Related articles

Ocular surface and MUC5AC alterations in atopic patients with corneal shield ulcers.

Dogru M, Asano-Kato N, Tanaka M, Igarashi A, Shimmura S, Shimazaki J, Okada N, Takano Y, Fukagawa K, Tsubota K, Fujishima H.

Curr Eye Res. 2005 Oct;30(10):897-908.PMID: 16251127 [PubMed - indexed for MEDLINE]Related articles