PubMed

Practitioners' views on managing childhood obesity in primary care: a qualitative study.

Turner KM, Shield JP, Salisbury C.

Br J Gen Pract. 2009 Nov;59(568):856-62. Epub 2009 Aug 26.PMID: 19712545 [PubMed - in process]Related articles

Hyperinsulinism-hyperammonaemia syndrome: novel mutations in the GLUD1 gene and genotype-phenotype correlations.

Kapoor RR, Flanagan SE, Fulton P, Chakrapani A, Chadefaux B, Ben-Omran T, Banerjee I, Shield JP, Ellard S, Hussain K.

Eur J Endocrinol. 2009 Nov;161(5):731-5. Epub 2009 Aug 18.PMID: 19690084 [PubMed - indexed for MEDLINE]Related articlesFree article

Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy.

Lennon R, Pons D, Sabin MA, Wei C, Shield JP, Coward RJ, Tavaré JM, Mathieson PW, Saleem MA, Welsh GI.

Nephrol Dial Transplant. 2009 Nov;24(11):3288-96. Epub 2009 Jun 25.PMID: 19556298 [PubMed - in process]Related articles

Hypercholesterolaemia in children guidelines review.

Baumer JH, Shield JP.

Arch Dis Child Educ Pract Ed. 2009 Jun;94(3):84-6. Review. No abstract available. PMID: 19460897 [PubMed - indexed for MEDLINE]Related articles

Protection from clinical peripheral sensory neuropathy in Alström syndrome in contrast to early-onset type 2 diabetes.

Paisey RB, Paisey RM, Thomson MP, Bower L, Maffei P, Shield JP, Barnett S, Marshall JD.

Diabetes Care. 2009 Mar;32(3):462-4. Epub 2008 Dec 17.PMID: 19092165 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical heterogeneity in patients with FOXP3 mutations presenting with permanent neonatal diabetes.

Rubio-Cabezas O, Minton JA, Caswell R, Shield JP, Deiss D, Sumnik Z, Cayssials A, Herr M, Loew A, Lewis V, Ellard S, Hattersley AT.

Diabetes Care. 2009 Jan;32(1):111-6. Epub 2008 Oct 17.PMID: 18931102 [PubMed - in process]Related articlesFree article

Management and 1 year outcome for UK children with type 2 diabetes.

Shield JP, Lynn R, Wan KC, Haines L, Barrett TG.

Arch Dis Child. 2009 Mar;94(3):206-9. Epub 2008 Oct 6.PMID: 18838418 [PubMed - indexed for MEDLINE]Related articles

Elevated glucose concentrations during an oral glucose tolerance test are associated with the presence of metabolic syndrome in childhood obesity.

Sabin MA, Hunt LP, Ford AL, Werther GA, Crowne EC, Shield JP.

Diabet Med. 2008 Mar;25(3):289-95.PMID: 18307456 [PubMed - indexed for MEDLINE]Related articles

Neonatal diabetes.

Shield JP.

Horm Res. 2007;68 Suppl 5:32-6. Epub 2007 Dec 10. Review.PMID: 18174703 [PubMed - indexed for MEDLINE]Related articles

Childhood obesity.

Sabin MA, Shield JP.

Front Horm Res. 2008;36:85-96. Review.PMID: 18230896 [PubMed - indexed for MEDLINE]Related articles

Peripheral neuropathy is an early complication of type 2 diabetes in adolescence.

Karabouta Z, Barnett S, Shield JP, Ryan FJ, Crowne EC.

Pediatr Diabetes. 2008 Apr;9(2):110-4. Epub 2008 Jan 19.PMID: 18221439 [PubMed - indexed for MEDLINE]Related articles

Fasting nonesterified fatty acid profiles in childhood and their relationship with adiposity, insulin sensitivity, and lipid levels.

Sabin MA, De Hora M, Holly JM, Hunt LP, Ford AL, Williams SR, Baker JS, Retallick CJ, Crowne EC, Shield JP.

Pediatrics. 2007 Dec;120(6):e1426-33.PMID: 18055661 [PubMed - indexed for MEDLINE]Related articlesFree article

Mosaic paternal uniparental isodisomy and an ABCC8 gene mutation in a patient with permanent neonatal diabetes and hemihypertrophy.

Shield JP, Flanagan SE, Mackay DJ, Harries LW, Proks P, Girard C, Ashcroft FM, Temple IK, Ellard S.

Diabetes. 2008 Jan;57(1):255-8. Epub 2007 Oct 17.PMID: 17942821 [PubMed - indexed for MEDLINE]Related articlesFree article

Is there a place for bariatric surgery in treating childhood obesity?

Shield JP, Crowne E, Morgan J.

Arch Dis Child. 2008 May;93(5):369-72. Epub 2007 Oct 1. No abstract available. PMID: 17908715 [PubMed - indexed for MEDLINE]Related articles

Teesside Schools Health Study: body mass index surveillance in special needs and mainstream school children.

Ells LJ, Shield JP, Lidstone JS, Tregonning D, Whittaker V, Batterham A, Wilkinson JR, Summerbell CD.

Public Health. 2008 Mar;122(3):251-4. Epub 2007 Sep 10. No abstract available. PMID: 17826811 [PubMed - indexed for MEDLINE]Related articles

Permanent neonatal diabetes caused by dominant, recessive, or compound heterozygous SUR1 mutations with opposite functional effects.

Ellard S, Flanagan SE, Girard CA, Patch AM, Harries LW, Parrish A, Edghill EL, Mackay DJ, Proks P, Shimomura K, Haberland H, Carson DJ, Shield JP, Hattersley AT, Ashcroft FM.

Am J Hum Genet. 2007 Aug;81(2):375-82. Epub 2007 Jun 29.PMID: 17668386 [PubMed - indexed for MEDLINE]Related articlesFree article

Depot-specific effects of fatty acids on lipid accumulation in children's adipocytes.

Sabin MA, Crowne EC, Stewart CE, Hunt LP, Turner SJ, Welsh GI, Grohmann MJ, Holly JM, Shield JP.

Biochem Biophys Res Commun. 2007 Sep 21;361(2):356-61. Epub 2007 Jul 16.PMID: 17643395 [PubMed - indexed for MEDLINE]Related articles

Which factors are associated with a successful outcome in a weight management programme for obese children?

Sabin MA, Ford A, Hunt L, Jamal R, Crowne EC, Shield JP.

J Eval Clin Pract. 2007 Jun;13(3):364-8.PMID: 17518800 [PubMed - indexed for MEDLINE]Related articles

Mutations in ATP-sensitive K+ channel genes cause transient neonatal diabetes and permanent diabetes in childhood or adulthood.

Flanagan SE, Patch AM, Mackay DJ, Edghill EL, Gloyn AL, Robinson D, Shield JP, Temple K, Ellard S, Hattersley AT.

Diabetes. 2007 Jul;56(7):1930-7. Epub 2007 Apr 19. Erratum in: Diabetes. 2008 Feb;57(2):523. PMID: 17446535 [PubMed - indexed for MEDLINE]Related articlesFree article

Macrosomia and hyperinsulinaemic hypoglycaemia in patients with heterozygous mutations in the HNF4A gene.

Pearson ER, Boj SF, Steele AM, Barrett T, Stals K, Shield JP, Ellard S, Ferrer J, Hattersley AT.

PLoS Med. 2007 Apr;4(4):e118.PMID: 17407387 [PubMed - indexed for MEDLINE]Related articlesFree article

Clinical measures of adiposity and percentage fat loss: which measure most accurately reflects fat loss and what should we aim for?

Hunt LP, Ford A, Sabin MA, Crowne EC, Shield JP.

Arch Dis Child. 2007 May;92(5):399-403. Epub 2007 Jan 29.PMID: 17261578 [PubMed - indexed for MEDLINE]Related articles

Rising incidence of type 2 diabetes in children in the U.K.

Haines L, Wan KC, Lynn R, Barrett TG, Shield JP.

Diabetes Care. 2007 May;30(5):1097-101. Epub 2007 Jan 26.PMID: 17259470 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acid-induced defects in insulin signalling, in myotubes derived from children, are related to ceramide production from palmitate rather than the accumulation of intramyocellular lipid.

Sabin MA, Stewart CE, Crowne EC, Turner SJ, Hunt LP, Welsh GI, Grohmann MJ, Holly JM, Shield JP.

J Cell Physiol. 2007 Apr;211(1):244-52.PMID: 17219404 [PubMed - indexed for MEDLINE]Related articles

Clinical, enzymatic and molecular characterization of nine new patients with malonyl-coenzyme A decarboxylase deficiency.

Salomons GS, Jakobs C, Pope LL, Errami A, Potter M, Nowaczyk M, Olpin S, Manning N, Raiman JA, Slade T, Champion MP, Peck D, Gavrilov D, Hillman R, Hoganson GE, Donaldson K, Shield JP, Ketteridge D, Wasserstein M, Gibson KM.

J Inherit Metab Dis. 2007 Feb;30(1):23-8. Epub 2006 Dec 20.PMID: 17186413 [PubMed - indexed for MEDLINE]Related articles

Islet autoimmunity in children with Down's syndrome.

Gillespie KM, Dix RJ, Williams AJ, Newton R, Robinson ZF, Bingley PJ, Gale EA, Shield JP.

Diabetes. 2006 Nov;55(11):3185-8.PMID: 17065360 [PubMed - indexed for MEDLINE]Related articlesFree article

Neonatal diabetes: how research unravelling the genetic puzzle has both widened our understanding of pancreatic development whilst improving children's quality of life.

Shield JP.

Horm Res. 2007;67(2):77-83. Epub 2006 Oct 17. Review.PMID: 17047341 [PubMed - indexed for MEDLINE]Related articles

Obesity and disability - a short review.

Ells LJ, Lang R, Shield JP, Wilkinson JR, Lidstone JS, Coulton S, Summerbell CD.

Obes Rev. 2006 Nov;7(4):341-5. Review.PMID: 17038128 [PubMed - indexed for MEDLINE]Related articles

A maternal hypomethylation syndrome presenting as transient neonatal diabetes mellitus.

Mackay DJ, Boonen SE, Clayton-Smith J, Goodship J, Hahnemann JM, Kant SG, Njølstad PR, Robin NH, Robinson DO, Siebert R, Shield JP, White HE, Temple IK.

Hum Genet. 2006 Sep;120(2):262-9. Epub 2006 Jul 1.PMID: 16816970 [PubMed - indexed for MEDLINE]Related articles

Fluorine-18 L-3,4-dihydroxyphenylalanine positron emission tomography: improving surgery and outcome in focal hyperinsulinism. Commentary to Mohnike et al.: Proposal for a standardized protocol for F-DOPA-PET (PET/CT) in congenital hyperinsulinism (Horm Res 2006;66:40-42).

Shield JP.

Horm Res. 2006;66(1):43-4. Epub 2006 May 19. No abstract available. PMID: 16710095 [PubMed - indexed for MEDLINE]Related articles

Sensori-neural deafness and hypothyroidism: autoimmunity causing 'pseudo-Pendred syndrome'.

Davis N, Lunardi C, Shield JP.

Horm Res. 2006;65(6):267-8. Epub 2006 Mar 21.PMID: 16582570 [PubMed - indexed for MEDLINE]Related articles

Sporadic intragenic inversion of the mitochondrial DNA MTND1 gene causing fatal infantile lactic acidosis.

Blakely EL, Rennie KJ, Jones L, Elstner M, Chrzanowska-Lightowlers ZM, White CB, Shield JP, Pilz DT, Turnbull DM, Poulton J, Taylor RW.

Pediatr Res. 2006 Mar;59(3):440-4.PMID: 16492986 [PubMed - indexed for MEDLINE]Related articles

Epimutation of the TNDM locus and the Beckwith-Wiedemann syndrome centromeric locus in individuals with transient neonatal diabetes mellitus.

Mackay DJ, Hahnemann JM, Boonen SE, Poerksen S, Bunyan DJ, White HE, Durston VJ, Thomas NS, Robinson DO, Shield JP, Clayton-Smith J, Temple IK.

Hum Genet. 2006 Mar;119(1-2):179-84. Epub 2006 Jan 5.PMID: 16402210 [PubMed - indexed for MEDLINE]Related articles

Mature subcutaneous and visceral adipocyte concentrations of adiponectin are highly correlated in prepubertal children and inversely related to body mass index standard deviation score.

Sabin MA, Holly JM, Shield JP, Turner SJ, Grohmann MJ, Stewart CE, Crowne EC.

J Clin Endocrinol Metab. 2006 Jan;91(1):332-5. Epub 2005 Oct 25.PMID: 16249291 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterisation of morbidity in a UK, hospital based, obesity clinic.

Sabin MA, Ford AL, Holly JM, Hunt LP, Crowne EC, Shield JP.

Arch Dis Child. 2006 Feb;91(2):126-30. Epub 2005 Oct 24.PMID: 16246852 [PubMed - indexed for MEDLINE]Related articlesFree article

Bone marrow transplantation correcting beta-galactosidase activity does not influence neurological outcome in juvenile GM1-gangliosidosis.

Shield JP, Stone J, Steward CG.

J Inherit Metab Dis. 2005;28(5):797-8.PMID: 16151914 [PubMed - indexed for MEDLINE]Related articles

Physical activity patterns in nonobese and obese children assessed using minute-by-minute accelerometry.

Page A, Cooper AR, Stamatakis E, Foster LJ, Crowne EC, Sabin M, Shield JP.

Int J Obes (Lond). 2005 Sep;29(9):1070-6.PMID: 15917845 [PubMed - indexed for MEDLINE]Related articles

Relapsing diabetes can result from moderately activating mutations in KCNJ11.

Gloyn AL, Reimann F, Girard C, Edghill EL, Proks P, Pearson ER, Temple IK, Mackay DJ, Shield JP, Freedenberg D, Noyes K, Ellard S, Ashcroft FM, Gribble FM, Hattersley AT.

Hum Mol Genet. 2005 Apr 1;14(7):925-34. Epub 2005 Feb 17.PMID: 15718250 [PubMed - indexed for MEDLINE]Related articlesFree article

Mutations of the catalytic subunit of RAB3GAP cause Warburg Micro syndrome.

Aligianis IA, Johnson CA, Gissen P, Chen D, Hampshire D, Hoffmann K, Maina EN, Morgan NV, Tee L, Morton J, Ainsworth JR, Horn D, Rosser E, Cole TR, Stolte-Dijkstra I, Fieggen K, Clayton-Smith J, Mégarbané A, Shield JP, Newbury-Ecob R, Dobyns WB, Graham JM Jr, Kjaer KW, Warburg M, Bond J, Trembath RC, Harris LW, Takai Y, Mundlos S, Tannahill D, Woods CG, Maher ER.

Nat Genet. 2005 Mar;37(3):221-3.PMID: 15696165 [PubMed - indexed for MEDLINE]Related articles

Bisulphite sequencing of the transient neonatal diabetes mellitus DMR facilitates a novel diagnostic test but reveals no methylation anomalies in patients of unknown aetiology.

Mackay DJ, Temple IK, Shield JP, Robinson DO.

Hum Genet. 2005 Mar;116(4):255-61. Epub 2005 Jan 6.PMID: 15635480 [PubMed - indexed for MEDLINE]Related articles

Beta-cell dysfunction in classic transient neonatal diabetes is characterized by impaired insulin response to glucose but normal response to glucagon.

Valerio G, Franzese A, Salerno M, Muzzi G, Cecere G, Temple KI, Shield JP.

Diabetes Care. 2004 Oct;27(10):2405-8.PMID: 15451908 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired glucose homeostasis in transgenic mice expressing the human transient neonatal diabetes mellitus locus, TNDM.

Ma D, Shield JP, Dean W, Leclerc I, Knauf C, Burcelin R R, Rutter GA, Kelsey G.

J Clin Invest. 2004 Aug;114(3):339-48.PMID: 15286800 [PubMed - indexed for MEDLINE]Related articlesFree article

An assessment of pancreatic endocrine function and insulin sensitivity in patients with transient neonatal diabetes in remission.

Shield JP, Temple IK, Sabin M, Mackay D, Robinson DO, Betts PR, Carson DJ, Cavé H, Chevenne D, Polak M.

Arch Dis Child Fetal Neonatal Ed. 2004 Jul;89(4):F341-3.PMID: 15210671 [PubMed - indexed for MEDLINE]Related articlesFree article

Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes.

Gloyn AL, Pearson ER, Antcliff JF, Proks P, Bruining GJ, Slingerland AS, Howard N, Srinivasan S, Silva JM, Molnes J, Edghill EL, Frayling TM, Temple IK, Mackay D, Shield JP, Sumnik Z, van Rhijn A, Wales JK, Clark P, Gorman S, Aisenberg J, Ellard S, Njølstad PR, Ashcroft FM, Hattersley AT.

N Engl J Med. 2004 Apr 29;350(18):1838-49. Erratum in: N Engl J Med. 2004 Sep 30;351(14):1470. PMID: 15115830 [PubMed - indexed for MEDLINE]Related articlesFree article

Neonatal diabetes mellitus.

Shield JP, Temple IK.

Pediatr Diabetes. 2002 Jun;3(2):109-12. No abstract available. PMID: 15016165 [PubMed]Related articles

Acute respiratory distress syndrome in long-chain 3-hydroxyacyl-CoA dehydrogenase and mitochondrial trifunctional protein deficiencies.

Lundy CT, Shield JP, Kvittingen EA, Vinorum OJ, Trimble ER, Morris AA.

J Inherit Metab Dis. 2003;26(6):537-41.PMID: 14605499 [PubMed - indexed for MEDLINE]Related articles

Transient neonatal diabetes, a disorder of imprinting.

Temple IK, Shield JP.

J Med Genet. 2002 Dec;39(12):872-5. Review.PMID: 12471198 [PubMed - indexed for MEDLINE]Related articlesFree article

Understanding neonatal diabetes mellitus.

Shield JP.

J Pediatr. 2002 Oct;141(4):462-3. No abstract available. PMID: 12378179 [PubMed - indexed for MEDLINE]Related articles

Symptomatic adrenal insufficiency presenting with hypoglycaemia in children with asthma receiving high dose inhaled fluticasone propionate.

Drake AJ, Howells RJ, Shield JP, Prendiville A, Ward PS, Crowne EC.

BMJ. 2002 May 4;324(7345):1081-2. No abstract available. PMID: 11991916 [PubMed - indexed for MEDLINE]Related articlesFree article

Complete glucokinase deficiency is not a common cause of permanent neonatal diabetes.

Gloyn AL, Ellard S, Shield JP, Temple IK, Mackay DJ, Polak M, Barrett T, Hattersley AT.

Diabetologia. 2002 Feb;45(2):290. No abstract available. PMID: 11942315 [PubMed - indexed for MEDLINE]Related articles

Relaxation of imprinted expression of ZAC and HYMAI in a patient with transient neonatal diabetes mellitus.

Mackay DJ, Coupe AM, Shield JP, Storr JN, Temple IK, Robinson DO.

Hum Genet. 2002 Feb;110(2):139-44. Epub 2002 Jan 24.PMID: 11935319 [PubMed - indexed for MEDLINE]Related articles