PubMed

Cytosolic phospholipase A2alpha activation induced by S1P is mediated by the S1P3 receptor in lung epithelial cells.

Chen LY, Woszczek G, Nagineni S, Logun C, Shelhamer JH.

Am J Physiol Lung Cell Mol Physiol. 2008 Aug;295(2):L326-35. Epub 2008 May 23.PMID: 18502815 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-10 inhibits cysteinyl leukotriene-induced activation of human monocytes and monocyte-derived dendritic cells.

Woszczek G, Chen LY, Nagineni S, Shelhamer JH.

J Immunol. 2008 Jun 1;180(11):7597-603.PMID: 18490762 [PubMed - indexed for MEDLINE]Related articlesFree article

Leukotriene D(4) induces gene expression in human monocytes through cysteinyl leukotriene type I receptor.

Woszczek G, Chen LY, Nagineni S, Kern S, Barb J, Munson PJ, Logun C, Danner RL, Shelhamer JH.

J Allergy Clin Immunol. 2008 Jan;121(1):215-221.e1. Epub 2007 Oct 29.PMID: 18028998 [PubMed - indexed for MEDLINE]Related articles

85-kDa cytosolic phospholipase A2 group IValpha gene promoter polymorphisms in patients with severe asthma: a gene expression and case-control study.

Sokolowska M, Borowiec M, Ptasinska A, Cieslak M, Shelhamer JH, Kowalski ML, Pawliczak R.

Clin Exp Immunol. 2007 Oct;150(1):124-31. Epub 2007 Aug 2.PMID: 17672871 [PubMed - indexed for MEDLINE]Related articlesFree article

IFN-gamma induces cysteinyl leukotriene receptor 2 expression and enhances the responsiveness of human endothelial cells to cysteinyl leukotrienes.

Woszczek G, Chen LY, Nagineni S, Alsaaty S, Harry A, Logun C, Pawliczak R, Shelhamer JH.

J Immunol. 2007 Apr 15;178(8):5262-70.PMID: 17404310 [PubMed - indexed for MEDLINE]Related articlesFree article

TLR4-NOX4-AP-1 signaling mediates lipopolysaccharide-induced CXCR6 expression in human aortic smooth muscle cells.

Patel DN, Bailey SR, Gresham JK, Schuchman DB, Shelhamer JH, Goldstein BJ, Foxwell BM, Stemerman MB, Maranchie JK, Valente AJ, Mummidi S, Chandrasekar B.

Biochem Biophys Res Commun. 2006 Sep 8;347(4):1113-20. Epub 2006 Jul 13.PMID: 16870145 [PubMed - indexed for MEDLINE]Related articles

Polyamine-mediated reduction in human airway epithelial migration in response to wounding is PGE2 dependent through decreases in COX-2 and cPLA2 protein levels.

Cowan MJ, Coll T, Shelhamer JH.

J Appl Physiol. 2006 Oct;101(4):1127-35. Epub 2006 Jun 1.PMID: 16741257 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression profiles of peripheral blood leukocytes after endotoxin challenge in humans.

Talwar S, Munson PJ, Barb J, Fiuza C, Cintron AP, Logun C, Tropea M, Khan S, Reda D, Shelhamer JH, Danner RL, Suffredini AF.

Physiol Genomics. 2006 Apr 13;25(2):203-15. Epub 2006 Jan 10.PMID: 16403844 [PubMed - indexed for MEDLINE]Related articlesFree article

Functional characterization of human cysteinyl leukotriene 1 receptor gene structure.

Woszczek G, Pawliczak R, Qi HY, Nagineni S, Alsaaty S, Logun C, Shelhamer JH.

J Immunol. 2005 Oct 15;175(8):5152-9.PMID: 16210619 [PubMed - indexed for MEDLINE]Related articlesFree article

Toll-like receptor 4 signaling regulates cytosolic phospholipase A2 activation and lipid generation in lipopolysaccharide-stimulated macrophages.

Qi HY, Shelhamer JH.

J Biol Chem. 2005 Nov 25;280(47):38969-75. Epub 2005 Sep 21.PMID: 16176925 [PubMed - indexed for MEDLINE]Related articlesFree article

Influence of IFN-gamma on gene expression in normal human bronchial epithelial cells: modulation of IFN-gamma effects by dexamethasone.

Pawliczak R, Logun C, Madara P, Barb J, Suffredini AF, Munson PJ, Danner RL, Shelhamer JH.

Physiol Genomics. 2005 Sep 21;23(1):28-45. Epub 2005 Jun 28.PMID: 15985639 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of TFIID, the initiator element and a novel 5' TFIID binding site in the transcriptional control of the TATA-less human cytosolic phospholipase A2-alpha promoter.

Cowan MJ, Yao XL, Pawliczak R, Huang X, Logun C, Madara P, Alsaaty S, Wu T, Shelhamer JH.

Biochim Biophys Acta. 2004 Nov 5;1680(3):145-57.PMID: 15507318 [PubMed - indexed for MEDLINE]Related articles

Cytosolic phospholipase A2 Group IValpha but not secreted phospholipase A2 Group IIA, V, or X induces interleukin-8 and cyclooxygenase-2 gene and protein expression through peroxisome proliferator-activated receptors gamma 1 and 2 in human lung cells.

Pawliczak R, Logun C, Madara P, Lawrence M, Woszczek G, Ptasinska A, Kowalski ML, Wu T, Shelhamer JH.

J Biol Chem. 2004 Nov 19;279(47):48550-61. Epub 2004 Aug 25.PMID: 15331599 [PubMed - indexed for MEDLINE]Related articlesFree article

Transforming growth factor-beta (TGF-beta) activates cytosolic phospholipase A2alpha (cPLA2alpha)-mediated prostaglandin E2 (PGE)2/EP1 and peroxisome proliferator-activated receptor-gamma (PPAR-gamma)/Smad signaling pathways in human liver cancer cells. A novel mechanism for subversion of TGF-beta-induced mitoinhibition.

Han C, Demetris AJ, Liu Y, Shelhamer JH, Wu T.

J Biol Chem. 2004 Oct 22;279(43):44344-54. Epub 2004 Aug 4.PMID: 15294900 [PubMed - indexed for MEDLINE]Related articlesFree article

Blood mononuclear cell gene expression profiles characterize the oxidant, hemolytic, and inflammatory stress of sickle cell disease.

Jison ML, Munson PJ, Barb JJ, Suffredini AF, Talwar S, Logun C, Raghavachari N, Beigel JH, Shelhamer JH, Danner RL, Gladwin MT.

Blood. 2004 Jul 1;104(1):270-80. Epub 2004 Mar 18.PMID: 15031206 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of p38 and p42/44 MAP kinases and protein kinase C in the interferon-gamma and interleukin-1alpha-induced phosphorylation of 85-kDa cytosolic phospholipase A(2) in primary human bronchial epithelial cells.

Wu T, Han C, Shelhamer JH.

Cytokine. 2004 Jan 7;25(1):11-20.PMID: 14687581 [PubMed - indexed for MEDLINE]Related articles

Application of functional genomics in allergy and clinical immunology.

Pawliczak R, Shelhamer JH.

Allergy. 2003 Oct;58(10):973-80. Review. No abstract available. PMID: 14510713 [PubMed - indexed for MEDLINE]Related articles

PPARgamma ligands inhibit cholangiocarcinoma cell growth through p53-dependent GADD45 and p21 pathway.

Han C, Demetris AJ, Michalopoulos GK, Zhan Q, Shelhamer JH, Wu T.

Hepatology. 2003 Jul;38(1):167-77.PMID: 12829999 [PubMed - indexed for MEDLINE]Related articles

Characterization of the human p11 promoter sequence.

Huang X, Pawliczak R, Yao XL, Madara P, Alsaaty S, Shelhamer JH, Cowan MJ.

Gene. 2003 May 22;310:133-42.PMID: 12801640 [PubMed - indexed for MEDLINE]Related articles

Interferon-gamma induces p11 gene and protein expression in human epithelial cells through interferon-gamma-activated sequences in the p11 promoter.

Huang XL, Pawliczak R, Yao XL, Cowan MJ, Gladwin MT, Walter MJ, Holtzman MJ, Madara P, Logun C, Shelhamer JH.

J Biol Chem. 2003 Mar 14;278(11):9298-308.PMID: 12645529 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidant-induced cell death in respiratory epithelial cells is due to DNA damage and loss of ATP.

Nanavaty UB, Pawliczak R, Doniger J, Gladwin MT, Cowan MJ, Logun C, Shelhamer JH.

Exp Lung Res. 2002 Dec;28(8):591-607.PMID: 12490035 [PubMed - indexed for MEDLINE]Related articles

Inflammation-promoting activity of HMGB1 on human microvascular endothelial cells.

Fiuza C, Bustin M, Talwar S, Tropea M, Gerstenberger E, Shelhamer JH, Suffredini AF.

Blood. 2003 Apr 1;101(7):2652-60. Epub 2002 Nov 27.PMID: 12456506 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway.

Pawliczak R, Huang XL, Nanavaty UB, Lawrence M, Madara P, Shelhamer JH.

Am J Respir Cell Mol Biol. 2002 Dec;27(6):722-31.PMID: 12444032 [PubMed - indexed for MEDLINE]Related articlesFree article

Epidermal growth factor induces p11 gene and protein expression and down-regulates calcium ionophore-induced arachidonic acid release in human epithelial cells.

Huang XL, Pawliczak R, Cowan MJ, Gladwin MT, Madara P, Logun C, Shelhamer JH.

J Biol Chem. 2002 Oct 11;277(41):38431-40. Epub 2002 Aug 5.PMID: 12163506 [PubMed - indexed for MEDLINE]Related articlesFree article

Involvement of 85-kd cytosolic phospholipase A(2) and cyclooxygenase-2 in the proliferation of human cholangiocarcinoma cells.

Wu T, Han C, Lunz JG 3rd, Michalopoulos G, Shelhamer JH, Demetris AJ.

Hepatology. 2002 Aug;36(2):363-73.PMID: 12143044 [PubMed - indexed for MEDLINE]Related articles

85-kDa cytosolic phospholipase A2 mediates peroxisome proliferator-activated receptor gamma activation in human lung epithelial cells.

Pawliczak R, Han C, Huang XL, Demetris AJ, Shelhamer JH, Wu T.

J Biol Chem. 2002 Sep 6;277(36):33153-63. Epub 2002 Jun 20.PMID: 12077117 [PubMed - indexed for MEDLINE]Related articlesFree article

85-kDa cPLA(2) plays a critical role in PPAR-mediated gene transcription in human hepatoma cells.

Han C, Demetris AJ, Michalopoulos G, Shelhamer JH, Wu T.

Am J Physiol Gastrointest Liver Physiol. 2002 Apr;282(4):G586-97.PMID: 11897617 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide donor properties of hydroxyurea in patients with sickle cell disease.

Gladwin MT, Shelhamer JH, Ognibene FP, Pease-Fye ME, Nichols JS, Link B, Patel DB, Jankowski MA, Pannell LK, Schechter AN, Rodgers GP.

Br J Haematol. 2002 Feb;116(2):436-44.PMID: 11841449 [PubMed - indexed for MEDLINE]Related articles

CT virtual bronchoscopy of the central airways in patients with Wegener's granulomatosis.

Summers RM, Aggarwal NR, Sneller MC, Cowan MJ, Wood BJ, Langford CA, Shelhamer JH.

Chest. 2002 Jan;121(1):242-50.PMID: 11796457 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide transport on sickle cell hemoglobin: where does it bind?

Gladwin MT, Ognibene FP, Shelhamer JH, Pease-Fye ME, Noguchi CT, Rodgers GP, Schechter AN.

Free Radic Res. 2001 Aug;35(2):175-80.PMID: 11697198 [PubMed - indexed for MEDLINE]Related articles

p11 expression in human bronchial epithelial cells is increased by nitric oxide in a cGMP-dependent pathway involving protein kinase G activation.

Pawliczak R, Cowan MJ, Huang X, Nanavaty UB, Alsaaty S, Logun C, Shelhamer JH.

J Biol Chem. 2001 Nov 30;276(48):44613-21. Epub 2001 Sep 24.PMID: 11571284 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of inhaled nitric oxide on regional blood flow are consistent with intravascular nitric oxide delivery.

Cannon RO 3rd, Schechter AN, Panza JA, Ognibene FP, Pease-Fye ME, Waclawiw MA, Shelhamer JH, Gladwin MT.

J Clin Invest. 2001 Jul;108(2):279-87.PMID: 11457881 [PubMed - indexed for MEDLINE]Related articlesFree article

Disorders of ciliary motility.

Cowan MJ, Gladwin MT, Shelhamer JH.

Am J Med Sci. 2001 Jan;321(1):3-10. Review.PMID: 11202477 [PubMed - indexed for MEDLINE]Related articles

Tumor necrosis factor alpha stimulation of human Clara cell secretory protein production by human airway epithelial cells.

Cowan MJ, Huang X, Yao XL, Shelhamer JH.

Ann N Y Acad Sci. 2000;923:193-201. Review.PMID: 11193757 [PubMed - indexed for MEDLINE]Related articles

Prostaglandin E(2)-induced interleukin-6 release by a human airway epithelial cell line.

Tavakoli S, Cowan MJ, Benfield T, Logun C, Shelhamer JH.

Am J Physiol Lung Cell Mol Physiol. 2001 Jan;280(1):L127-33.PMID: 11133502 [PubMed - indexed for MEDLINE]Related articlesFree article

Retinoic acid reduces p11 protein levels in bronchial epithelial cells by a posttranslational mechanism.

Gladwin MT, Yao XL, Cowan M, Huang XL, Schneider R, Grant LR, Logun C, Shelhamer JH.

Am J Physiol Lung Cell Mol Physiol. 2000 Dec;279(6):L1103-9.PMID: 11076800 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of circulating nitrite and S-nitrosohemoglobin in the regulation of regional blood flow in humans.

Gladwin MT, Shelhamer JH, Schechter AN, Pease-Fye ME, Waclawiw MA, Panza JA, Ognibene FP, Cannon RO 3rd.

Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11482-7.PMID: 11027349 [PubMed - indexed for MEDLINE]Related articlesFree article

Pneumocystis pneumonia: miles to go.

Masur H, Shelhamer JH.

Chest. 2000 Sep;118(3):575-7. Review. No abstract available. PMID: 10988173 [PubMed - indexed for MEDLINE]Related articlesFree article

Relative role of heme nitrosylation and beta-cysteine 93 nitrosation in the transport and metabolism of nitric oxide by hemoglobin in the human circulation.

Gladwin MT, Ognibene FP, Pannell LK, Nichols JS, Pease-Fye ME, Shelhamer JH, Schechter AN.

Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):9943-8.PMID: 10954746 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhaled nitric oxide augments nitric oxide transport on sickle cell hemoglobin without affecting oxygen affinity.

Gladwin MT, Schechter AN, Shelhamer JH, Pannell LK, Conway DA, Hrinczenko BW, Nichols JS, Pease-Fye ME, Noguchi CT, Rodgers GP, Ognibene FP.

J Clin Invest. 1999 Oct;104(7):937-45.PMID: 10510334 [PubMed - indexed for MEDLINE]Related articlesFree article

Pneumocystis carinii major surface glycoprotein induces interleukin-8 and monocyte chemoattractant protein-1 release from a human alveolar epithelial cell line.

Benfield TL, Lundgren B, Shelhamer JH, Lundgren JD.

Eur J Clin Invest. 1999 Aug;29(8):717-22.PMID: 10457157 [PubMed - indexed for MEDLINE]Related articles

Dexamethasone alters arachidonate release from human epithelial cells by induction of p11 protein synthesis and inhibition of phospholipase A2 activity.

Yao XL, Cowan MJ, Gladwin MT, Lawrence MM, Angus CW, Shelhamer JH.

J Biol Chem. 1999 Jun 11;274(24):17202-8.PMID: 10358078 [PubMed - indexed for MEDLINE]Related articlesFree article

The acute chest syndrome in sickle cell disease. Possible role of nitric oxide in its pathophysiology and treatment.

Gladwin MT, Schechter AN, Shelhamer JH, Ognibene FP.

Am J Respir Crit Care Med. 1999 May;159(5 Pt 1):1368-76. Review. No abstract available. PMID: 10228097 [PubMed - indexed for MEDLINE]Related articlesFree article

Tumor necrosis factor-alpha stimulates human Clara cell secretory protein production by human airway epithelial cells.

Yao XL, Levine SJ, Cowan MJ, Logun C, Shelhamer JH.

Am J Respir Cell Mol Biol. 1998 Oct;19(4):629-35.PMID: 9761760 [PubMed - indexed for MEDLINE]Related articlesFree article

Polypoid lesions of airways: early experience with computer-assisted detection by using virtual bronchoscopy and surface curvature.

Summers RM, Selbie WS, Malley JD, Pusanik LM, Dwyer AJ, Courcoutsakis NA, Shaw DJ, Kleiner DE, Sneller MC, Langford CA, Holland SM, Shelhamer JH.

Radiology. 1998 Aug;208(2):331-7.PMID: 9680555 [PubMed - indexed for MEDLINE]Related articlesFree article

Interferon-gamma stimulates human Clara cell secretory protein production by human airway epithelial cells.

Yao XL, Ikezono T, Cowan M, Logun C, Angus CW, Shelhamer JH.

Am J Physiol. 1998 May;274(5 Pt 1):L864-9.PMID: 9612303 [PubMed - indexed for MEDLINE]Related articlesFree article

CT virtual bronchoscopy of simulated endobronchial lesions: effect of scanning, reconstruction, and display settings and potential pitfalls.

Summers RM, Shaw DJ, Shelhamer JH.

AJR Am J Roentgenol. 1998 Apr;170(4):947-50. No abstract available. PMID: 9530041 [PubMed - indexed for MEDLINE]Related articlesFree article

The major surface glycoprotein of Pneumocystis carinii induces release and gene expression of interleukin-8 and tumor necrosis factor alpha in monocytes.

Benfield TL, Lundgren B, Levine SJ, Kronborg G, Shelhamer JH, Lundgren JD.

Infect Immun. 1997 Nov;65(11):4790-4.PMID: 9353066 [PubMed - indexed for MEDLINE]Related articlesFree article

Antisense inhibition of 85-kDa cPLA2 blocks arachidonic acid release from airway epithelial cells.

Wu T, Levine SJ, Cowan M, Logun C, Angus CW, Shelhamer JH.

Am J Physiol. 1997 Aug;273(2 Pt 1):L331-8.PMID: 9277444 [PubMed - indexed for MEDLINE]Related articles

P11, a unique member of the S100 family of calcium-binding proteins, interacts with and inhibits the activity of the 85-kDa cytosolic phospholipase A2.

Wu T, Angus CW, Yao XL, Logun C, Shelhamer JH.

J Biol Chem. 1997 Jul 4;272(27):17145-53.PMID: 9202034 [PubMed - indexed for MEDLINE]Related articlesFree article