PubMed

Reconstitution of hematin for intravenous infusion.

Anderson KE, Bonkovsky HL, Bloomer JR, Shedlofsky SI.

Ann Intern Med. 2006 Apr 4;144(7):537-8. No abstract available. PMID: 16585674 [PubMed - indexed for MEDLINE]Related articlesFree article

Microarray gene analysis of the liver in a rat model of chronic, voluntary alcohol intake.

Deaciuc IV, Peng X, D'Souza NB, Shedlofsky SI, Burikhanov R, Voskresensky IV, de Villiers WJ.

Alcohol. 2004 Feb;32(2):113-27.PMID: 15163562 [PubMed - indexed for MEDLINE]Related articles

Does iron reduction improve sustained viral responses to interferon monotherapy in hepatitis C patients? Maybe, but is this the right question?

Shedlofsky SI.

Am J Gastroenterol. 2002 May;97(5):1093-6. Review. No abstract available. PMID: 12014712 [PubMed - indexed for MEDLINE]Related articles

The effect of endotoxin on hepatocyte nuclear factor 1 nuclear protein binding: potential implications on CYP2E1 expression in the rat.

Roe AL, Poloyac SM, Howard G, Shedlofsky SI, Blouin RA.

J Pharm Pharmacol. 2001 Oct;53(10):1365-71.PMID: 11697544 [PubMed - indexed for MEDLINE]Related articles

Depression of constitutive murine cytochromes P450 by staphylococcal enterotoxin B.

Shedlofsky SI, Tosheva RT, Snawder JA.

Biochem Pharmacol. 2000 May 15;59(10):1295-303.PMID: 10736430 [PubMed - indexed for MEDLINE]Related articles

The effect of endotoxin administration on the pharmacokinetics of chlorzoxazone in humans.

Poloyac SM, Tosheva RT, Gardner BM, Shedlofsky SI, Blouin RA.

Clin Pharmacol Ther. 1999 Dec;66(6):554-62.PMID: 10613610 [PubMed - indexed for MEDLINE]Related articles

Activities of conjugating and antioxidant enzymes following endotoxin exposure.

Watson AM, Warren G, Howard G, Shedlofsky SI, Blouin RA.

J Biochem Mol Toxicol. 1999;13(2):63-9.PMID: 9890190 [PubMed - indexed for MEDLINE]Related articles

The effect of high dose endotoxin on CYP3A2 expression in the rat.

Roe AL, Warren G, Hou G, Howard G, Shedlofsky SI, Blouin RA.

Pharm Res. 1998 Oct;15(10):1603-8.PMID: 9794504 [PubMed - indexed for MEDLINE]Related articles

Role of iron in the natural history and clinical course of hepatitis C disease.

Shedlofsky SI.

Hepatogastroenterology. 1998 Mar-Apr;45(20):349-55. Review.PMID: 9638405 [PubMed - indexed for MEDLINE]Related articles

Ascorbic acid deficiency in porphyria cutanea tarda.

Sinclair PR, Gorman N, Shedlofsky SI, Honsinger CP, Sinclair JF, Karagas MR, Anderson KE.

J Lab Clin Med. 1997 Aug;130(2):197-201.PMID: 9280147 [PubMed - indexed for MEDLINE]Related articles

Effects of endotoxin on zinc metabolism in human volunteers.

Gaetke LM, McClain CJ, Talwalkar RT, Shedlofsky SI.

Am J Physiol. 1997 Jun;272(6 Pt 1):E952-6.PMID: 9227437 [PubMed - indexed for MEDLINE]Related articles

Endotoxin depresses hepatic cytochrome P450-mediated drug metabolism in women.

Shedlofsky SI, Israel BC, Tosheva R, Blouin RA.

Br J Clin Pharmacol. 1997 Jun;43(6):627-32.PMID: 9205823 [PubMed - indexed for MEDLINE]Related articlesFree article

In vitro tumor necrosis factor cytotoxicity in Hep G2 liver cells.

Hill DB, Schmidt J, Shedlofsky SI, Cohen DA, McClain CJ.

Hepatology. 1995 Apr;21(4):1114-9.PMID: 7535734 [PubMed - indexed for MEDLINE]Related articles

Endotoxin administration to humans inhibits hepatic cytochrome P450-mediated drug metabolism.

Shedlofsky SI, Israel BC, McClain CJ, Hill DB, Blouin RA.

J Clin Invest. 1994 Dec;94(6):2209-14.PMID: 7989576 [PubMed - indexed for MEDLINE]Related articlesFree article

Head injury and cytochrome P-450 enzymes. Differential effect on mRNA and protein expression in the Fischer-344 rat.

Toler SM, Young AB, McClain CJ, Shedlofsky SI, Bandyopadhyay AM, Blouin RA.

Drug Metab Dispos. 1993 Nov-Dec;21(6):1064-9.PMID: 7905385 [PubMed - indexed for MEDLINE]Related articles

Effects of interferon-alpha monotherapy on hepatic drug metabolism in cancer patients.

Israel BC, Blouin RA, McIntyre W, Shedlofsky SI.

Br J Clin Pharmacol. 1993 Sep;36(3):229-35.PMID: 9114909 [PubMed - indexed for MEDLINE]Related articlesFree article

The calcium channel blocker nisoldipine minimizes the release of tumor necrosis factor and interleukin-6 following rat liver transplantation.

Savier E, Shedlofsky SI, Swim AT, Lemasters JJ, Thurman RG.

Transpl Int. 1992;5 Suppl 1:S398-402.PMID: 14621831 [PubMed - indexed for MEDLINE]Related articles

Age-dependent stereoselective increase in the oral clearance of hexobarbitone isomers caused by rifampicin.

Smith DA, Chandler MH, Shedlofsky SI, Wedlund PJ, Blouin RA.

Br J Clin Pharmacol. 1991 Dec;32(6):735-9.PMID: 1768567 [PubMed - indexed for MEDLINE]Related articlesFree article

3,3',4,4'-Tetrabromobiphenyl sensitizes rats to the hepatotoxic effects of endotoxin by a mechanism that involves more than tumor necrosis factor.

Shedlofsky SI, Hoglen NC, Rodman LE, Honchel R, Robinson FR, Swim AT, McClain CJ, Robertson LW.

Hepatology. 1991 Dec;14(6):1201-8.PMID: 1660020 [PubMed - indexed for MEDLINE]Related articles

Identification of a novel serum amyloid A protein in BALB/c mice.

de Beer MC, Beach CM, Shedlofsky SI, de Beer FC.

Biochem J. 1991 Nov 15;280 ( Pt 1):45-9.PMID: 1741755 [PubMed - indexed for MEDLINE]Related articlesFree article

Differential potency of atropisomers of polychlorinated biphenyls on cytochrome P450 induction and uroporphyrin accumulation in the chick embryo hepatocyte culture.

Rodman LE, Shedlofsky SI, Mannschreck A, Püttmann M, Swim AT, Robertson LW.

Biochem Pharmacol. 1991 Mar 15-Apr 1;41(6-7):915-22.PMID: 1901208 [PubMed - indexed for MEDLINE]Related articles

Effects of polychlorinated biphenyls on cytochrome P450 induction in the chick embryo hepatocyte culture.

Rodman LE, Shedlofsky SI, Swim AT, Robertson LW.

Arch Biochem Biophys. 1989 Nov 15;275(1):252-62.PMID: 2510602 [PubMed - indexed for MEDLINE]Related articles

Modulation of murine hematopoiesis in vivo with recombinant murine interleukin-1.

Gallicchio VS, Shedlofsky SI, Swim AT, Robinson JM, Hulette BC, Messino MJ, Doukas MA.

J Biol Response Mod. 1989 Aug;8(4):422-39.PMID: 2666587 [PubMed - indexed for MEDLINE]Related articles

An update on hepatitis B viral disease.

Shedlofsky SI.

J Ky Med Assoc. 1988 Apr;86(4):181-6. Review. No abstract available. PMID: 2966844 [PubMed - indexed for MEDLINE]Related articles

Copper toxicity in Wilson's disease: an absorbing problem.

McClain CJ, Shedlofsky SI.

J Lab Clin Med. 1988 Mar;111(3):261-2. No abstract available. PMID: 3343539 [PubMed - indexed for MEDLINE]Related articles

Haem synthesis from exogenous 5-aminolaevulinate in cultured chick-embryo hepatocytes. Effects of inducers of cytochromes P-450.

Shedlofsky SI, Sinclair PR, Bonkovsky HL, Healey JF, Swim AT, Robinson JM.

Biochem J. 1987 Nov 15;248(1):229-36.PMID: 3435440 [PubMed - indexed for MEDLINE]Related articlesFree article

Interleukin-1 (IL-1) depresses cytochrome P450 levels and activities in mice.

Shedlofsky SI, Swim AT, Robinson JM, Gallicchio VS, Cohen DA, McClain CJ.

Life Sci. 1987 Jun 15;40(24):2331-6.PMID: 3295445 [PubMed - indexed for MEDLINE]Related articles

Zinc metabolism in alcoholic liver disease.

McClain CJ, Antonow DR, Cohen DA, Shedlofsky SI.

Alcohol Clin Exp Res. 1986 Dec;10(6):582-9. Review.PMID: 3544908 [PubMed - indexed for MEDLINE]Related articles

Serum interleukin-1 (IL-1) activity in alcoholic hepatitis.

McClain CJ, Cohen DA, Dinarello CA, Cannon JG, Shedlofsky SI, Kaplan AM.

Life Sci. 1986 Oct 20;39(16):1479-85.PMID: 3490610 [PubMed - indexed for MEDLINE]Related articles

Increased glutathione in cultured hepatocytes associated with induction of cytochrome P-450. Lack of effect of glutathione depletion on induction of cytochrome P-450 and delta-aminolevulinate synthase.

Shedlofsky SI, Sinclair PR, Sinclair JF, Bonkovsky HL.

Biochem Pharmacol. 1984 May 1;33(9):1487-91.PMID: 6375680 [PubMed - indexed for MEDLINE]Related articles

Seizure management in the hepatic porphyrias: results from a cell-culture model of porphyria.

Shedlofsky SI, Bonkowsky HL.

Neurology. 1984 Mar;34(3):399. No abstract available. PMID: 6538289 [PubMed - indexed for MEDLINE]Related articles

Effect of uroporphyrin on the spectral measurement of cytochrome P450.

Bonkovsky HL, Healey JF, Bement WJ, Sinclair PR, Sinclair JF, Shedlofsky SI.

Biochem Pharmacol. 1984 Feb 1;33(3):499-502. No abstract available. PMID: 6704169 [PubMed - indexed for MEDLINE]Related articles

Iron loading of cultured hepatocytes. Effect of iron on 5-aminolaevulinate synthase is independent of lipid peroxidation.

Shedlofsky SI, Bonkowsky HL, Sinclair PR, Sinclair JF, Bement WJ, Pomeroy JS.

Biochem J. 1983 May 15;212(2):321-30.PMID: 6882375 [PubMed - indexed for MEDLINE]Related articlesFree article

Iron and the liver: acute effects of iron-loading on hepatic heme synthesis of rats. Role of decreased activity of 5-aminolevulinate dehydrase.

Bonkowsky HL, Healey JF, Sinclair PR, Sinclair JF, Shedlofsky SI, Elder GH.

J Clin Invest. 1983 May;71(5):1175-82.PMID: 6189858 [PubMed - indexed for MEDLINE]Related articlesFree article