PubMed

Functional redundancy of exon 12 of BRCA2 revealed by a comprehensive analysis of the c.6853A>G (p.I2285V) variant.

Li L, Biswas K, Habib LA, Kuznetsov SG, Hamel N, Kirchhoff T, Wong N, Armel S, Chong G, Narod SA, Claes K, Offit K, Robson ME, Stauffer S, Sharan SK, Foulkes WD.

Hum Mutat. 2009 Nov;30(11):1543-50.PMID: 19795481 [PubMed - in process]Related articles

Expression of human BRCA1 variants in mouse ES cells allows functional analysis of BRCA1 mutations.

Chang S, Biswas K, Martin BK, Stauffer S, Sharan SK.

J Clin Invest. 2009 Oct;119(10):3160-71. doi: 10.1172/JCI39836. Epub 2009 Sep 21.PMID: 19770520 [PubMed - in process]Related articlesFree article

Port-wine vascular malformations and glaucoma risk in Sturge-Weber syndrome.

Sharan S, Swamy B, Taranath DA, Jamieson R, Yu T, Wargon O, Grigg JR.

J AAPOS. 2009 Aug;13(4):374-8.PMID: 19683189 [PubMed - indexed for MEDLINE]Related articles

Late-onset bleb infections: prevalence and risk factors.

Sharan S, Trope GE, Chipman M, Buys YM.

Can J Ophthalmol. 2009 Jun;44(3):279-83.PMID: 19491982 [PubMed - indexed for MEDLINE]Related articlesFree article

Chebulagic acid, a COX-LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz., induces apoptosis in COLO-205 cell line.

Reddy DB, Reddy TC, Jyotsna G, Sharan S, Priya N, Lakshmipathi V, Reddanna P.

J Ethnopharmacol. 2009 Jul 30;124(3):506-12. Epub 2009 May 28.PMID: 19481594 [PubMed - indexed for MEDLINE]Related articles

Recombineering: a homologous recombination-based method of genetic engineering.

Sharan SK, Thomason LC, Kuznetsov SG, Court DL.

Nat Protoc. 2009;4(2):206-23.PMID: 19180090 [PubMed - indexed for MEDLINE]Related articles

Loss of Rad51c leads to embryonic lethality and modulation of Trp53-dependent tumorigenesis in mice.

Kuznetsov SG, Haines DC, Martin BK, Sharan SK.

Cancer Res. 2009 Feb 1;69(3):863-72. Epub 2009 Jan 20.PMID: 19155299 [PubMed - indexed for MEDLINE]Related articles

A handcuff model for the cohesin complex.

Zhang N, Kuznetsov SG, Sharan SK, Li K, Rao PH, Pati D.

J Cell Biol. 2008 Dec 15;183(6):1019-31.PMID: 19075111 [PubMed - indexed for MEDLINE]Related articlesFree article

Degradation of BRCA2 in alkyltransferase-mediated DNA repair and its clinical implications.

Philip S, Swaminathan S, Kuznetsov SG, Kanugula S, Biswas K, Chang S, Loktionova NA, Haines DC, Kaldis P, Pegg AE, Sharan SK.

Cancer Res. 2008 Dec 1;68(23):9973-81.PMID: 19047179 [PubMed - indexed for MEDLINE]Related articles

Mouse embryonic stem cell-based functional assay to evaluate mutations in BRCA2.

Kuznetsov SG, Liu P, Sharan SK.

Nat Med. 2008 Aug;14(8):875-81. Epub 2008 Jul 6.PMID: 18607349 [PubMed - indexed for MEDLINE]Related articlesFree article

Elliptical anterior iris stromal defects associated with PAX6 gene sequence changes.

Sharan S, Mirzayans F, Footz T, Walter M, Levin AV.

J AAPOS. 2008 Aug;12(4):340-3. Epub 2008 Apr 25.PMID: 18440259 [PubMed - indexed for MEDLINE]Related articles

Model systems for studying skeletal dysplasias caused by TSP-5/COMP mutations.

Posey KL, Yang Y, Veerisetty AC, Sharan SK, Hecht JT.

Cell Mol Life Sci. 2008 Mar;65(5):687-99. Review.PMID: 18193163 [PubMed - indexed for MEDLINE]Related articles

The Cebpd (C/EBPdelta) gene is induced by luteinizing hormones in ovarian theca and interstitial cells but is not essential for mouse ovary function.

Huang AM, Rudelius M, Sharan S, McAllister JM, Raffeld M, Christenson LK, Sterneck E.

PLoS One. 2007 Dec 19;2(12):e1334.PMID: 18092000 [PubMed - indexed for MEDLINE]Related articlesFree article

Resolving RAD51C function in late stages of homologous recombination.

Sharan SK, Kuznetsov SG.

Cell Div. 2007 Jun 4;2:15.PMID: 17547768 [PubMed]Related articlesFree article

RAD51C deficiency in mice results in early prophase I arrest in males and sister chromatid separation at metaphase II in females.

Kuznetsov S, Pellegrini M, Shuda K, Fernandez-Capetillo O, Liu Y, Martin BK, Burkett S, Southon E, Pati D, Tessarollo L, West SC, Donovan PJ, Nussenzweig A, Sharan SK.

J Cell Biol. 2007 Feb 26;176(5):581-92. Epub 2007 Feb 20.PMID: 17312021 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of mutated mouse myocilin induces open-angle glaucoma in transgenic mice.

Senatorov V, Malyukova I, Fariss R, Wawrousek EF, Swaminathan S, Sharan SK, Tomarev S.

J Neurosci. 2006 Nov 15;26(46):11903-14.PMID: 17108164 [PubMed - indexed for MEDLINE]Related articlesFree article

Closed antegrade interlocked nailing of femoral shaft fractures operated up to 2 weeks postinjury in the absence of a fracture table or C-arm.

Aiyer S, Jagiasi J, Argekar H, Sharan S, Dasgupta B.

J Trauma. 2006 Aug;61(2):457-60.PMID: 16917468 [PubMed - indexed for MEDLINE]Related articles

Nanophthalmos: ultrasound biomicroscopy and Pentacam assessment of angle structures before and after cataract surgery.

Sharan S, Grigg JR, Higgins RA.

J Cataract Refract Surg. 2006 Jun;32(6):1052-5.PMID: 16814070 [PubMed - indexed for MEDLINE]Related articles

Congenital rubella cataract: a timely reminder in the new millennium?

Sharan S, Sharma S, Billson FA.

Clin Experiment Ophthalmol. 2006 Jan-Feb;34(1):83-4.PMID: 16451266 [PubMed - indexed for MEDLINE]Related articles

Bilateral naevus of Ota with choroidal melanoma and diffuse retinal pigmentation in a dark skinned person.

Sharan S, Grigg JR, Billson FA.

Br J Ophthalmol. 2005 Nov;89(11):1529. No abstract available. PMID: 16234467 [PubMed - indexed for MEDLINE]Related articlesFree article

C/EBPdelta is a crucial regulator of pro-apoptotic gene expression during mammary gland involution.

Thangaraju M, Rudelius M, Bierie B, Raffeld M, Sharan S, Hennighausen L, Huang AM, Sterneck E.

Development. 2005 Nov;132(21):4675-85. Epub 2005 Sep 28.PMID: 16192306 [PubMed - indexed for MEDLINE]Related articlesFree article

Anterior megalophthalmos in a family with 3 female siblings.

Sharan S, Billson FA.

J Cataract Refract Surg. 2005 Jul;31(7):1433-6.PMID: 16105619 [PubMed - indexed for MEDLINE]Related articles

Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models.

Difilippantonio S, Celeste A, Fernandez-Capetillo O, Chen HT, Reina San Martin B, Van Laethem F, Yang YP, Petukhova GV, Eckhaus M, Feigenbaum L, Manova K, Kruhlak M, Camerini-Otero RD, Sharan S, Nussenzweig M, Nussenzweig A.

Nat Cell Biol. 2005 Jul;7(7):675-85. Epub 2005 Jun 19.PMID: 15965469 [PubMed - indexed for MEDLINE]Related articles

Autoimmune retinopathy associated with intravesical BCG therapy.

Sharan S, Thirkill CE, Grigg JR.

Br J Ophthalmol. 2005 Jul;89(7):927-8. No abstract available. PMID: 15965187 [PubMed - indexed for MEDLINE]Related articlesFree article

Total hyphema following postoperative enoxaparin (Clexane).

Sharan S, Painter G, Grigg JR.

Eye (Lond). 2005 Jul;19(7):827-8. No abstract available. PMID: 15359239 [PubMed - indexed for MEDLINE]Related articles

BAC rescue: a tool for functional analysis of the mouse genome.

Swing DA, Sharan SK.

Methods Mol Biol. 2004;256:183-98. No abstract available. PMID: 15024167 [PubMed - indexed for MEDLINE]Related articles

Bacterial artificial chromosome engineering.

Swaminathan S, Sharan SK.

Methods Mol Biol. 2004;256:89-106. No abstract available. PMID: 15024162 [PubMed - indexed for MEDLINE]Related articles

Comparison of mammary gland involution between 129S1 and C57BL/6 inbred mouse strains: differential regulation of Bcl2a1, Trp53, Cebpb, and Cebpd expression.

Thangaraju M, Sharan S, Sterneck E.

Oncogene. 2004 Apr 1;23(14):2548-53.PMID: 14981542 [PubMed - indexed for MEDLINE]Related articles

Loss of CCAAT/enhancer binding protein delta promotes chromosomal instability.

Huang AM, Montagna C, Sharan S, Ni Y, Ried T, Sterneck E.

Oncogene. 2004 Feb 26;23(8):1549-57.PMID: 14716301 [PubMed - indexed for MEDLINE]Related articles

BRCA2 deficiency in mice leads to meiotic impairment and infertility.

Sharan SK, Pyle A, Coppola V, Babus J, Swaminathan S, Benedict J, Swing D, Martin BK, Tessarollo L, Evans JP, Flaws JA, Handel MA.

Development. 2004 Jan;131(1):131-42. Epub 2003 Dec 3.PMID: 14660434 [PubMed - indexed for MEDLINE]Related articlesFree article

Mini-lambda: a tractable system for chromosome and BAC engineering.

Court DL, Swaminathan S, Yu D, Wilson H, Baker T, Bubunenko M, Sawitzke J, Sharan SK.

Gene. 2003 Oct 2;315:63-9.PMID: 14557065 [PubMed - indexed for MEDLINE]Related articles

Aberrant splicing induced by missense mutations in BRCA1: clues from a humanized mouse model.

Yang Y, Swaminathan S, Martin BK, Sharan SK.

Hum Mol Genet. 2003 Sep 1;12(17):2121-31. Epub 2003 Jul 8.PMID: 12915465 [PubMed - indexed for MEDLINE]Related articlesFree article

A simple two-step, 'hit and fix' method to generate subtle mutations in BACs using short denatured PCR fragments.

Yang Y, Sharan SK.

Nucleic Acids Res. 2003 Aug 1;31(15):e80.PMID: 12888532 [PubMed - indexed for MEDLINE]Related articlesFree article

Healing of root resorption: a case report.

Bhat SS, Sharan SS, Madan I.

J Clin Pediatr Dent. 2003 Spring;27(3):235-8.PMID: 12739683 [PubMed - indexed for MEDLINE]Related articles

Is there any real virtue of virtual reality?: the minor role of multiple orientations in learning anatomy from computers.

Garg AX, Norman GR, Eva KW, Spero L, Sharan S.

Acad Med. 2002 Oct;77(10 Suppl):S97-9. No abstract available. PMID: 12377717 [PubMed - indexed for MEDLINE]Related articles

Brca2 (XRCC11) deficiency results in radioresistant DNA synthesis and a higher frequency of spontaneous deletions.

Kraakman-van der Zwet M, Overkamp WJ, van Lange RE, Essers J, van Duijn-Goedhart A, Wiggers I, Swaminathan S, van Buul PP, Errami A, Tan RT, Jaspers NG, Sharan SK, Kanaar R, Zdzienicka MZ.

Mol Cell Biol. 2002 Jan;22(2):669-79.PMID: 11756561 [PubMed - indexed for MEDLINE]Related articlesFree article

Sequence, chromosomal location and expression analysis of the murine homologue of human RAD51L2/RAD51C.

Leasure CS, Chandler J, Gilbert DJ, Householder DB, Stephens R, Copeland NG, Jenkins NA, Sharan SK.

Gene. 2001 Jun 13;271(1):59-67.PMID: 11410366 [PubMed - indexed for MEDLINE]Related articles

Syndrome of inappropriate antidiuretic hormone secretion occurring in association with urinary tract infection.

Achari V, Shrivastava DK, Sharan S.

J Assoc Physicians India. 1998 Jun;46(6):557-8. No abstract available. PMID: 11273259 [PubMed - indexed for MEDLINE]Related articles

Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.

Chandler J, Hohenstein P, Swing DA, Tessarollo L, Sharan SK.

Genesis. 2001 Feb;29(2):72-7.PMID: 11170347 [PubMed - indexed for MEDLINE]Related articles

Rapid engineering of bacterial artificial chromosomes using oligonucleotides.

Swaminathan S, Ellis HM, Waters LS, Yu D, Lee EC, Court DL, Sharan SK.

Genesis. 2001 Jan;29(1):14-21.PMID: 11135458 [PubMed - indexed for MEDLINE]Related articles

Functional characterization of BRCA1 and BRCA2: clues from their interacting proteins.

Sharan SK, Bradley A.

J Mammary Gland Biol Neoplasia. 1998 Oct;3(4):413-21. Review.PMID: 10819535 [PubMed - indexed for MEDLINE]Related articles

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2.

Sharan SK, Morimatsu M, Albrecht U, Lim DS, Regel E, Dinh C, Sands A, Eichele G, Hasty P, Bradley A.

Nature. 1997 Apr 24;386(6627):804-10.PMID: 9126738 [PubMed - indexed for MEDLINE]Related articles

Murine Brca2: sequence, map position, and expression pattern.

Sharan SK, Bradley A.

Genomics. 1997 Mar 1;40(2):234-41.PMID: 9119389 [PubMed - indexed for MEDLINE]Related articles

Identification and characterization of a microsatellite marker within murine Brca2 gene.

Sharan SK, Bradley A.

Mamm Genome. 1997 Jan;8(1):79. No abstract available. PMID: 9021166 [PubMed - indexed for MEDLINE]Related articles

... and secreted tumour suppressors.

Bradley A, Sharan SK.

Nat Genet. 1996 Jul;13(3):268-9; author reply 269-72. No abstract available. PMID: 8673123 [PubMed - indexed for MEDLINE]Related articles

Murine Brca1: sequence and significance for human missense mutations.

Sharan SK, Wims M, Bradley A.

Hum Mol Genet. 1995 Dec;4(12):2275-8.PMID: 8634698 [PubMed - indexed for MEDLINE]Related articles

Physical localization of eed: a region of mouse chromosome 7 required for gastrulation.

Holdener BC, Thomas JW, Schumacher A, Potter MD, Rinchik EM, Sharan SK, Magnuson T.

Genomics. 1995 Jun 10;27(3):447-56.PMID: 7558026 [PubMed - indexed for MEDLINE]Related articles

Role of transgenic mice in identification and characterization of tumour suppressor genes.

Sharan SK, Bradley A.

Cancer Surv. 1995;25:143-59. Review.PMID: 8718516 [PubMed - indexed for MEDLINE]Related articles

Mouse albino-deletions: from genetics to genes in development.

Holdener-Kenny B, Sharan SK, Magnuson T.

Bioessays. 1992 Dec;14(12):831-9. Review.PMID: 1365899 [PubMed - indexed for MEDLINE]Related articles

Genomic mapping within the albino-deletion complex using individual early postimplantation mouse embryos.

Sharan SK, Holdener-Kenny B, Threadgill DW, Magnuson T.

Mamm Genome. 1992;3(2):79-83.PMID: 1617218 [PubMed - indexed for MEDLINE]Related articles