PubMed

11beta-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle.

Morgan SA, Sherlock M, Gathercole LL, Lavery GG, Lenaghan C, Bujalska IJ, Laber D, Yu A, Convey G, Mayers R, Hegyi K, Sethi JK, Stewart PM, Smith DM, Tomlinson JW.

Diabetes. 2009 Nov;58(11):2506-15. Epub 2009 Aug 12.PMID: 19675138 [PubMed - in process]Related articles

Dact1, a nutritionally regulated preadipocyte gene, controls adipogenesis by coordinating the Wnt/beta-catenin signaling network.

Lagathu C, Christodoulides C, Virtue S, Cawthorn WP, Franzin C, Kimber WA, Nora ED, Campbell M, Medina-Gomez G, Cheyette BN, Vidal-Puig AJ, Sethi JK.

Diabetes. 2009 Mar;58(3):609-19. Epub 2008 Dec 10.PMID: 19073771 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipogenesis and WNT signalling.

Christodoulides C, Lagathu C, Sethi JK, Vidal-Puig A.

Trends Endocrinol Metab. 2009 Jan;20(1):16-24. Epub 2008 Nov 13. Review.PMID: 19008118 [PubMed - indexed for MEDLINE]Related articles

Wnt signalling at the crossroads of nutritional regulation.

Sethi JK, Vidal-Puig AJ.

Biochem J. 2008 Dec 1;416(2):e11-3.PMID: 18990086 [PubMed - indexed for MEDLINE]Related articles

Activation of beta-catenin signalling by GSK-3 inhibition increases p-glycoprotein expression in brain endothelial cells.

Lim JC, Kania KD, Wijesuriya H, Chawla S, Sethi JK, Pulaski L, Romero IA, Couraud PO, Weksler BB, Hladky SB, Barrand MA.

J Neurochem. 2008 Aug;106(4):1855-65. Epub 2008 Jul 4.PMID: 18624906 [PubMed - indexed for MEDLINE]Related articles

TNF-alpha and adipocyte biology.

Cawthorn WP, Sethi JK.

FEBS Lett. 2008 Jan 9;582(1):117-31. Epub 2007 Nov 26. Review.PMID: 18037376 [PubMed - indexed for MEDLINE]Related articles

Targeting fat to prevent diabetes.

Sethi JK, Vidal-Puig AJ.

Cell Metab. 2007 May;5(5):323-5.PMID: 17488634 [PubMed - indexed for MEDLINE]Related articles

Tumour necrosis factor-alpha inhibits adipogenesis via a beta-catenin/TCF4(TCF7L2)-dependent pathway.

Cawthorn WP, Heyd F, Hegyi K, Sethi JK.

Cell Death Differ. 2007 Jul;14(7):1361-73. Epub 2007 Apr 20.PMID: 17464333 [PubMed - indexed for MEDLINE]Related articlesFree article

Thematic review series: adipocyte biology. Adipose tissue function and plasticity orchestrate nutritional adaptation.

Sethi JK, Vidal-Puig AJ.

J Lipid Res. 2007 Jun;48(6):1253-62. Epub 2007 Mar 20. Review.PMID: 17374880 [PubMed - indexed for MEDLINE]Related articlesFree article

Is PBEF/visfatin/Nampt an authentic adipokine relevant to the metabolic syndrome?

Sethi JK.

Curr Hypertens Rep. 2007 Mar;9(1):33-8. Review.PMID: 17362669 [PubMed - indexed for MEDLINE]Related articles

Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity.

Aerts JM, Ottenhoff R, Powlson AS, Grefhorst A, van Eijk M, Dubbelhuis PF, Aten J, Kuipers F, Serlie MJ, Wennekes T, Sethi JK, O'Rahilly S, Overkleeft HS.

Diabetes. 2007 May;56(5):1341-9. Epub 2007 Feb 7.PMID: 17287460 [PubMed - indexed for MEDLINE]Related articlesFree article

IGF-binding protein-2 protects against the development of obesity and insulin resistance.

Wheatcroft SB, Kearney MT, Shah AM, Ezzat VA, Miell JR, Modo M, Williams SC, Cawthorn WP, Medina-Gomez G, Vidal-Puig A, Sethi JK, Crossey PA.

Diabetes. 2007 Feb;56(2):285-94.PMID: 17259371 [PubMed - indexed for MEDLINE]Related articlesFree article

The Wnt antagonist Dickkopf-1 and its receptors are coordinately regulated during early human adipogenesis.

Christodoulides C, Laudes M, Cawthorn WP, Schinner S, Soos M, O'Rahilly S, Sethi JK, Vidal-Puig A.

J Cell Sci. 2006 Jun 15;119(Pt 12):2613-20.PMID: 16763196 [PubMed - indexed for MEDLINE]Related articlesFree article

Regulation of insulin receptor substrate 1 pleckstrin homology domain by protein kinase C: role of serine 24 phosphorylation.

Nawaratne R, Gray A, Jørgensen CH, Downes CP, Siddle K, Sethi JK.

Mol Endocrinol. 2006 Aug;20(8):1838-52. Epub 2006 Mar 30.PMID: 16574739 [PubMed - indexed for MEDLINE]Related articlesFree article

WNT10B mutations in human obesity.

Christodoulides C, Scarda A, Granzotto M, Milan G, Dalla Nora E, Keogh J, De Pergola G, Stirling H, Pannacciulli N, Sethi JK, Federspil G, Vidal-Puig A, Farooqi IS, O'Rahilly S, Vettor R.

Diabetologia. 2006 Apr;49(4):678-84. Epub 2006 Feb 14.PMID: 16477437 [PubMed - indexed for MEDLINE]Related articles

Obesity: Adipogenesis and Insulin Resistance.

Sethi JK.

IDrugs. 2000 Aug;3(8):884-6.PMID: 16059802 [PubMed]Related articles

Visfatin: the missing link between intra-abdominal obesity and diabetes?

Sethi JK, Vidal-Puig A.

Trends Mol Med. 2005 Aug;11(8):344-7. Review.PMID: 16005682 [PubMed - indexed for MEDLINE]Related articles

The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform.

Medina-Gomez G, Virtue S, Lelliott C, Boiani R, Campbell M, Christodoulides C, Perrin C, Jimenez-Linan M, Blount M, Dixon J, Zahn D, Thresher RR, Aparicio S, Carlton M, Colledge WH, Kettunen MI, Seppänen-Laakso T, Sethi JK, O'Rahilly S, Brindle K, Cinti S, Oresic M, Burcelin R, Vidal-Puig A.

Diabetes. 2005 Jun;54(6):1706-16.PMID: 15919792 [PubMed - indexed for MEDLINE]Related articlesFree article

The peroxisome proliferator-activated receptor-gamma regulates murine pyruvate carboxylase gene expression in vivo and in vitro.

Jitrapakdee S, Slawik M, Medina-Gomez G, Campbell M, Wallace JC, Sethi JK, O'rahilly S, Vidal-Puig AJ.

J Biol Chem. 2005 Jul 22;280(29):27466-76. Epub 2005 May 25.PMID: 15917242 [PubMed - indexed for MEDLINE]Related articlesFree article

ETO/MTG8 is an inhibitor of C/EBPbeta activity and a regulator of early adipogenesis.

Rochford JJ, Semple RK, Laudes M, Boyle KB, Christodoulides C, Mulligan C, Lelliott CJ, Schinner S, Hadaschik D, Mahadevan M, Sethi JK, Vidal-Puig A, O'Rahilly S.

Mol Cell Biol. 2004 Nov;24(22):9863-72.PMID: 15509789 [PubMed - indexed for MEDLINE]Related articlesFree article

A burst of energy in metabolic disease research.

Sethi JK.

Genome Biol. 2004;5(6):327. Epub 2004 May 27. No abstract available. PMID: 15186487 [PubMed - indexed for MEDLINE]Related articlesFree article

Signalling activity of beta-catenin targeted to different subcellular compartments.

Hagen T, Sethi JK, Foxwell N, Vidal-Puig A.

Biochem J. 2004 Apr 15;379(Pt 2):471-7.PMID: 14733614 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of the POZ zinc finger transcription factor FBI-1 in human and murine adipogenesis.

Laudes M, Christodoulides C, Sewter C, Rochford JJ, Considine RV, Sethi JK, Vidal-Puig A, O'Rahilly S.

J Biol Chem. 2004 Mar 19;279(12):11711-8. Epub 2003 Dec 30.PMID: 14701838 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo.

Meirhaeghe A, Crowley V, Lenaghan C, Lelliott C, Green K, Stewart A, Hart K, Schinner S, Sethi JK, Yeo G, Brand MD, Cortright RN, O'Rahilly S, Montague C, Vidal-Puig AJ.

Biochem J. 2003 Jul 1;373(Pt 1):155-65.PMID: 12678921 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterisation of receptor-specific TNFalpha functions in adipocyte cell lines lacking type 1 and 2 TNF receptors.

Sethi JK, Xu H, Uysal KT, Wiesbrock SM, Scheja L, Hotamisligil GS.

FEBS Lett. 2000 Mar 3;469(1):77-82.PMID: 10708760 [PubMed - indexed for MEDLINE]Related articles

Transmembrane tumor necrosis factor (TNF)-alpha inhibits adipocyte differentiation by selectively activating TNF receptor 1.

Xu H, Sethi JK, Hotamisligil GS.

J Biol Chem. 1999 Sep 10;274(37):26287-95.PMID: 10473584 [PubMed - indexed for MEDLINE]Related articlesFree article

The role of TNF alpha in adipocyte metabolism.

Sethi JK, Hotamisligil GS.

Semin Cell Dev Biol. 1999 Feb;10(1):19-29. Review.PMID: 10355025 [PubMed - indexed for MEDLINE]Related articles

Roles for adenosine ribose hydroxyl groups in cyclic adenosine 5'-diphosphate ribose-mediated Ca2+ release.

Ashamu GA, Sethi JK, Galione A, Potter BV.

Biochemistry. 1997 Aug 5;36(31):9509-17.PMID: 9235996 [PubMed - indexed for MEDLINE]Related articles

7-Deaza-8-bromo-cyclic ADP-ribose, the first membrane-permeant, hydrolysis-resistant cyclic ADP-ribose antagonist.

Sethi JK, Empson RM, Bailey VC, Potter BV, Galione A.

J Biol Chem. 1997 Jun 27;272(26):16358-63.PMID: 9195942 [PubMed - indexed for MEDLINE]Related articlesFree article

7-Deaza cyclic adenosine 5'-diphosphate ribose: first example of a Ca(2+)-mobilizing partial agonist related to cyclic adenosine 5'-diphosphate ribose.

Bailey VC, Sethi JK, Fortt SM, Galione A, Potter BV.

Chem Biol. 1997 Jan;4(1):51-61.PMID: 9070427 [PubMed - indexed for MEDLINE]Related articles

Nicotinamide inhibits cyclic ADP-ribose-mediated calcium signalling in sea urchin eggs.

Sethi JK, Empson RM, Galione A.

Biochem J. 1996 Oct 15;319 ( Pt 2):613-7.PMID: 8912702 [PubMed - indexed for MEDLINE]Related articlesFree article

Nitric oxide-induced mobilization of intracellular calcium via the cyclic ADP-ribose signaling pathway.

Willmott N, Sethi JK, Walseth TF, Lee HC, White AM, Galione A.

J Biol Chem. 1996 Feb 16;271(7):3699-705.PMID: 8631983 [PubMed - indexed for MEDLINE]Related articlesFree article

Inhibition of psychrotrophic organisms by propionicin PLG-1, a bacteriocin produced by Propionibacterium thoenii.

Lyon WJ, Sethi JK, Glatz BA.

J Dairy Sci. 1993 Jun;76(6):1506-13.PMID: 8326023 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of dietary fat on the in vitro hepatotoxicity of paracetamol.

McDanell RE, Beales D, Henderson L, Sethi JK.

Biochem Pharmacol. 1992 Oct 6;44(7):1303-6.PMID: 1417954 [PubMed - indexed for MEDLINE]Related articles

Effect of paracetamol on mitochondrial membrane function in rat liver slices.

Nazareth WM, Sethi JK, McLean AE.

Biochem Pharmacol. 1991 Jul 25;42(4):931-6.PMID: 1867647 [PubMed - indexed for MEDLINE]Related articles

Simethicone in the management of infant colic.

Sethi KS, Sethi JK.

Practitioner. 1988 May 9;232(1448):508. No abstract available. PMID: 3064072 [PubMed - indexed for MEDLINE]Related articles

Reversible acquisition of a host cell surface membrane antigen by Trypanosoma cruzi.

Chess Q, Acosta AM, Sethi JK, Santos-Buch CA.

Infect Immun. 1983 Apr;40(1):299-302.PMID: 6187692 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of human sarcoma antigen S3.

Sethi JK, Hirshaut Y.

Br J Cancer. 1981 Mar;43(3):261-6.PMID: 6164380 [PubMed - indexed for MEDLINE]Related articlesFree article

Variation in expression of S3 antigen in human sarcoma cell lines: influence of passages and medium on generation of S3.

Sethi JK, Hirshaut Y.

Eur J Cancer. 1978 Nov;14(11):1229-35. No abstract available. PMID: 570108 [PubMed - indexed for MEDLINE]Related articles