PubMed

Harnessing the weight-regulating properties of glucagon-like peptide-1 in the treatment of type 2 diabetes.

Sesti G.

Diabetes Obes Metab. 2009 Dec;11 Suppl 3:4-10.PMID: 19878256 [PubMed - in process]Related articles

An empirical index of insulin sensitivity from short IVGTT: validation against the minimal model and glucose clamp indices in patients with different clinical characteristics.

Tura A, Sbrignadello S, Succurro E, Groop L, Sesti G, Pacini G.

Diabetologia. 2009 Oct 30. [Epub ahead of print]PMID: 19876614 [PubMed - as supplied by publisher]Related articles

GRB10 gene and type 2 diabetes in Whites.

Di Paola R, Wojcik J, Succurro E, Marucci A, Chandalia M, Padovano L, Powers C, Merla G, Abate N, Sesti G, Doria A, Trischitta V.

J Intern Med. 2009 Oct 10. [Epub ahead of print] No abstract available. PMID: 19818100 [PubMed - as supplied by publisher]Related articles

Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study.

Boesgaard TW, Gjesing AP, Grarup N, Rutanen J, Jansson PA, Hribal ML, Sesti G, Fritsche A, Stefan N, Staiger H, Häring H, Smith U, Laakso M, Pedersen O, Hansen T; EUGENE2 Consortium.

PLoS One. 2009 Sep 30;4(9):e7236.PMID: 19789630 [PubMed - in process]Related articlesFree article

IRS1 G972R polymorphism and type 2 diabetes: a paradigm for the difficult ascertainment of the contribution to disease susceptibility of 'low-frequency-low-risk' variants.

Morini E, Prudente S, Succurro E, Chandalia M, Zhang YY, Mammarella S, Pellegrini F, Powers C, Proto V, Dallapiccola B, Cama A, Sesti G, Abate N, Doria A, Trischitta V.

Diabetologia. 2009 Sep;52(9):1852-7. Epub 2009 Jun 26.PMID: 19557384 [PubMed - in process]Related articles

Renal function predicts cardiovascular outcomes in southern Italian postmenopausal women.

Perticone F, Sciacqua A, Maio R, Perticone M, Laino I, Bruni R, Cello SD, Leone GG, Greco L, Andreozzi F, Sesti G.

Eur J Cardiovasc Prev Rehabil. 2009 Aug;16(4):481-6.PMID: 19531955 [PubMed - indexed for MEDLINE]Related articles

Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6).

Buse JB, Rosenstock J, Sesti G, Schmidt WE, Montanya E, Brett JH, Zychma M, Blonde L; LEAD-6 Study Group.

Lancet. 2009 Jul 4;374(9683):39-47. Epub 2009 Jun 8.PMID: 19515413 [PubMed - indexed for MEDLINE]Related articles

Elevated one-hour post-load plasma glucose levels identifies subjects with normal glucose tolerance but early carotid atherosclerosis.

Succurro E, Marini MA, Arturi F, Grembiale A, Lugarà M, Andreozzi F, Sciacqua A, Lauro R, Hribal ML, Perticone F, Sesti G.

Atherosclerosis. 2009 Nov;207(1):245-9. Epub 2009 Apr 11.PMID: 19410252 [PubMed - in process]Related articles

Leptin-stimulated endothelial nitric-oxide synthase via an adenosine 5'-monophosphate-activated protein kinase/Akt signaling pathway is attenuated by interaction with C-reactive protein.

Procopio C, Andreozzi F, Laratta E, Cassese A, Beguinot F, Arturi F, Hribal ML, Perticone F, Sesti G.

Endocrinology. 2009 Aug;150(8):3584-93. Epub 2009 Apr 9.PMID: 19359389 [PubMed - indexed for MEDLINE]Related articles

Low plasma insulin-like growth factor-1 levels are associated with reduced insulin sensitivity and increased insulin secretion in nondiabetic subjects.

Succurro E, Andreozzi F, Marini MA, Lauro R, Hribal ML, Perticone F, Sesti G.

Nutr Metab Cardiovasc Dis. 2009 Dec;19(10):713-9. Epub 2009 Apr 5.PMID: 19346116 [PubMed - in process]Related articles

Differences in cardiovascular risk profile based on relationship between post-load plasma glucose and fasting plasma levels.

Succurro E, Marini MA, Grembiale A, Lugarà M, Andreozzi F, Sciacqua A, Hribal ML, Lauro R, Perticone F, Sesti G.

Diabetes Metab Res Rev. 2009 May;25(4):351-6.PMID: 19319930 [PubMed - indexed for MEDLINE]Related articles

IL-18 gene polymorphism and metabolic syndrome.

Presta I, Andreozzi F, Succurro E, Marini MA, Laratta E, Lauro R, Hribal ML, Perticone F, Sesti G.

Nutr Metab Cardiovasc Dis. 2009 Feb;19(2):e5-6. Epub 2009 Jan 26. No abstract available. PMID: 19176284 [PubMed - indexed for MEDLINE]Related articles

Endothelial dysfunction, ADMA and insulin resistance in essential hypertension.

Perticone F, Sciacqua A, Maio R, Perticone M, Galiano Leone G, Bruni R, Di Cello S, Pascale A, Talarico G, Greco L, Andreozzi F, Sesti G.

Int J Cardiol. 2009 Jan 23. [Epub ahead of print]PMID: 19168237 [PubMed - as supplied by publisher]Related articles

Variance of the SGK1 gene is associated with insulin secretion in different European populations: results from the TUEF, EUGENE2, and METSIM studies.

Friedrich B, Weyrich P, Stancáková A, Wang J, Kuusisto J, Laakso M, Sesti G, Succurro E, Smith U, Hansen T, Pedersen O, Machicao F, Schäfer S, Lang F, Risler T, Ullrich S, Stefan N, Fritsche A, Häring HU.

PLoS One. 2008;3(11):e3506. Epub 2008 Nov 5.PMID: 18985156 [PubMed - indexed for MEDLINE]Related articlesFree article

The TRIB3 Q84R polymorphism and risk of early-onset type 2 diabetes.

Prudente S, Scarpelli D, Chandalia M, Zhang YY, Morini E, Del Guerra S, Perticone F, Li R, Powers C, Andreozzi F, Marchetti P, Dallapiccola B, Abate N, Doria A, Sesti G, Trischitta V.

J Clin Endocrinol Metab. 2009 Jan;94(1):190-6. Epub 2008 Nov 4.PMID: 18984671 [PubMed - indexed for MEDLINE]Related articles

Elevated concentrations of liver enzymes and ferritin identify a new phenotype of insulin resistance: effect of weight loss after gastric banding.

Gastaldelli A, Perego L, Paganelli M, Sesti G, Hribal M, Chavez AO, Defronzo RA, Pontiroli A, Folli F.

Obes Surg. 2009 Jan;19(1):80-6. Epub 2008 Sep 24.PMID: 18820980 [PubMed - indexed for MEDLINE]Related articles

Insulin secretion in metabolically obese, but normal weight, and in metabolically healthy but obese individuals.

Succurro E, Marini MA, Frontoni S, Hribal ML, Andreozzi F, Lauro R, Perticone F, Sesti G.

Obesity (Silver Spring). 2008 Aug;16(8):1881-6. Epub 2008 Jun 12.PMID: 18551117 [PubMed - indexed for MEDLINE]Related articles

PTP1B deficiency increases glucose uptake in neonatal hepatocytes: involvement of IRA/GLUT2 complexes.

González-Rodriguez A, Nevado C, Escrivá F, Sesti G, Rondinone CM, Benito M, Valverde AM.

Am J Physiol Gastrointest Liver Physiol. 2008 Aug;295(2):G338-47. Epub 2008 Jun 5.PMID: 18535291 [PubMed - indexed for MEDLINE]Related articlesFree article

Reciprocal association of plasma IGF-1 and interleukin-6 levels with cardiometabolic risk factors in nondiabetic subjects.

Succurro E, Andreozzi F, Sciaqua A, Hribal ML, Perticone F, Sesti G.

Diabetes Care. 2008 Sep;31(9):1886-8. Epub 2008 Jun 5.PMID: 18535190 [PubMed - indexed for MEDLINE]Related articlesFree article

TRIB3 R84 variant is associated with impaired insulin-mediated nitric oxide production in human endothelial cells.

Andreozzi F, Formoso G, Prudente S, Hribal ML, Pandolfi A, Bellacchio E, Di Silvestre S, Trischitta V, Consoli A, Sesti G.

Arterioscler Thromb Vasc Biol. 2008 Jul;28(7):1355-60. Epub 2008 Apr 24.PMID: 18436806 [PubMed - indexed for MEDLINE]Related articlesFree article

Low-plasma insulin-like growth factor-I levels are associated with impaired endothelium-dependent vasodilatation in a cohort of untreated, hypertensive Caucasian subjects.

Perticone F, Sciacqua A, Perticone M, Laino I, Miceli S, Care' I, Galiano Leone G, Andreozzi F, Maio R, Sesti G.

J Clin Endocrinol Metab. 2008 Jul;93(7):2806-10. Epub 2008 Apr 22.PMID: 18430768 [PubMed - indexed for MEDLINE]Related articlesFree article

Kidney function and risk factors for left ventricular hypertrophy in untreated uncomplicated essential hypertension.

Perticone F, Maio R, Ruberto C, Cassano S, Tripepi G, Perticone M, Sesti G, Zoccali C.

Am J Kidney Dis. 2008 Jul;52(1):74-84. Epub 2008 Apr 18.PMID: 18423813 [PubMed - indexed for MEDLINE]Related articles

The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study.

Boesgaard TW, Zilinskaite J, Vänttinen M, Laakso M, Jansson PA, Hammarstedt A, Smith U, Stefan N, Fritsche A, Häring H, Hribal M, Sesti G, Zobel DP, Pedersen O, Hansen T; EUGENE 2 Consortium.

Diabetologia. 2008 May;51(5):816-20. Epub 2008 Mar 7.PMID: 18324385 [PubMed - indexed for MEDLINE]Related articles

Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance.

Stancáková A, Pihlajamäki J, Kuusisto J, Stefan N, Fritsche A, Häring H, Andreozzi F, Succurro E, Sesti G, Boesgaard TW, Hansen T, Pedersen O, Jansson PA, Hammarstedt A, Smith U, Laakso M; EUGENE2 Consortium.

J Clin Endocrinol Metab. 2008 May;93(5):1924-30. Epub 2008 Feb 19.PMID: 18285412 [PubMed - indexed for MEDLINE]Related articlesFree article

Transgenic mice overexpressing human G972R IRS-1 show impaired insulin action and insulin secretion.

Hribal ML, Tornei F, Pujol A, Menghini R, Barcaroli D, Lauro D, Amoruso R, Lauro R, Bosch F, Sesti G, Federici M.

J Cell Mol Med. 2008 Oct;12(5B):2096-106. Epub 2008 Jan 19.PMID: 18208559 [PubMed - indexed for MEDLINE]Related articles

The CCR2 promoter polymorphism T-960A, but not the serum MCP-1 level, is associated with endothelial function in prediabetic individuals.

Rittig K, Peter A, Baltz KM, Tschritter O, Weigert C, Andreozzi F, Perticone F, Siegel-Axel DI, Stefan N, Fritsche A, Salih HR, Schleicher E, Machicao F, Sesti G, Häring HU, Balletshofer BM.

Atherosclerosis. 2008 Jun;198(2):338-46. Epub 2007 Dec 21.PMID: 18096169 [PubMed - indexed for MEDLINE]Related articles

Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study.

Laakso M, Zilinskaite J, Hansen T, Boesgaard TW, Vänttinen M, Stancáková A, Jansson PA, Pellmé F, Holst JJ, Kuulasmaa T, Hribal ML, Sesti G, Stefan N, Fritsche A, Häring H, Pedersen O, Smith U; EUGENE2 Consortium.

Diabetologia. 2008 Mar;51(3):502-11. Epub 2007 Dec 14.PMID: 18080106 [PubMed - indexed for MEDLINE]Related articles

A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study.

Staiger H, Stancáková A, Zilinskaite J, Vänttinen M, Hansen T, Marini MA, Hammarstedt A, Jansson PA, Sesti G, Smith U, Pedersen O, Laakso M, Stefan N, Fritsche A, Häring HU.

Diabetes. 2008 Feb;57(2):514-7. Epub 2007 Nov 26.PMID: 18039816 [PubMed - indexed for MEDLINE]Related articlesFree article

Endothelial dysfunction and C-reactive protein are risk factors for diabetes in essential hypertension.

Perticone F, Maio R, Sciacqua A, Andreozzi F, Iemma G, Perticone M, Zoccali C, Sesti G.

Diabetes. 2008 Jan;57(1):167-71. Epub 2007 Oct 10.PMID: 17928395 [PubMed - indexed for MEDLINE]Related articlesFree article

Impact of lowering the criterion for impaired fasting glucose on identification of individuals with insulin resistance. The GISIR database.

Sesti G, Andreozzi F, Bonadonna RC, De Mattia G, Leonetti F, Luzi L, Marini MA, Natali A, Vettor R, Bonora E; Group of Italian Scientists of Insulin Resistance (GISIR).

Diabetes Metab Res Rev. 2008 Feb;24(2):130-6.PMID: 17922529 [PubMed - indexed for MEDLINE]Related articles

Gly460Trp alpha-adducin gene polymorphism and endothelial function in untreated hypertensive patients.

Perticone F, Sciacqua A, Barlassina C, Del Vecchio L, Signorello MC, Dal Fiume C, Andreozzi F, Sesti G, Cusi D.

J Hypertens. 2007 Nov;25(11):2234-9. Erratum in: J Hypertens. 2008 Feb;26(2):380. PMID: 17921817 [PubMed - indexed for MEDLINE]Related articles

Glutamine to arginine substitution at amino acid 84 of mammalian tribbles homolog TRIB3 and CKD in whites with type 2 diabetes.

De Cosmo S, Prudente S, Andreozzi F, Morini E, Rauseo A, Scarpelli D, Zhang YY, Xu R, Perticone F, Dallapiccola B, Sesti G, Doria A, Trischitta V.

Am J Kidney Dis. 2007 Oct;50(4):688-9. No abstract available. PMID: 17900474 [PubMed - indexed for MEDLINE]Related articles

Relation between serum uric acid and carotid intima-media thickness in healthy postmenopausal women.

Montalcini T, Gorgone G, Gazzaruso C, Sesti G, Perticone F, Pujia A.

Intern Emerg Med. 2007 Mar;2(1):19-23. Epub 2007 Mar 31.PMID: 17551679 [PubMed - indexed for MEDLINE]Related articles

Metabolically healthy but obese women have an intermediate cardiovascular risk profile between healthy nonobese women and obese insulin-resistant women.

Marini MA, Succurro E, Frontoni S, Hribal ML, Andreozzi F, Lauro R, Perticone F, Sesti G.

Diabetes Care. 2007 Aug;30(8):2145-7. Epub 2007 May 16. No abstract available. PMID: 17507694 [PubMed - indexed for MEDLINE]Related articlesFree article

Heterogeneous effect of peroxisome proliferator-activated receptor gamma2 Ala12 variant on type 2 diabetes risk.

Ludovico O, Pellegrini F, Di Paola R, Minenna A, Mastroianno S, Cardellini M, Marini MA, Andreozzi F, Vaccaro O, Sesti G, Trischitta V.

Obesity (Silver Spring). 2007 May;15(5):1076-81.PMID: 17495182 [PubMed - indexed for MEDLINE]Related articles

Correspondence between the International Diabetes Federation criteria for metabolic syndrome and insulin resistance in a cohort of Italian nondiabetic Caucasians: the GISIR database.

Sesti G, Capaldo B, Cavallo Perin P, Del Prato S, Frittitta L, Frontoni S, Hribal ML, Marchesini G, Paolisso G, Piatti PM, Solini A, Bonora E; Group of Italian Scientists of Insulin Resistance.

Diabetes Care. 2007 May;30(5):e33. No abstract available. PMID: 17468362 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of endogenous androgens on carotid atherosclerosis in non-obese postmenopausal women.

Montalcini T, Gorgone G, Gazzaruso C, Sesti G, Perticone F, Pujia A.

Nutr Metab Cardiovasc Dis. 2007 Dec;17(10):705-11. Epub 2007 Mar 28.PMID: 17395446 [PubMed - indexed for MEDLINE]Related articles

Role of PC-1 and ACE genes on insulin resistance and cardiac mass in never-treated hypertensive patients. Suggestive evidence for a digenic additive modulation.

Perticone F, Maio R, Di Paola R, Sciacqua A, Marucci A, De Cosmo S, Perticone M, Sesti G, Trischitta V.

Nutr Metab Cardiovasc Dis. 2007 Mar;17(3):181-7. Epub 2006 Mar 20.PMID: 17367703 [PubMed - indexed for MEDLINE]Related articles

Metabolic and cardiovascular risk factors in subjects with impaired fasting glucose: the 100 versus 110 mg/dL threshold.

Andreozzi F, Succurro E, Mancuso MR, Perticone M, Sciacqua A, Perticone F, Sesti G.

Diabetes Metab Res Rev. 2007 Oct;23(7):547-50.PMID: 17311284 [PubMed - indexed for MEDLINE]Related articles

C-reactive protein induces phosphorylation of insulin receptor substrate-1 on Ser307 and Ser 612 in L6 myocytes, thereby impairing the insulin signalling pathway that promotes glucose transport.

D'Alessandris C, Lauro R, Presta I, Sesti G.

Diabetologia. 2007 Apr;50(4):840-9. Epub 2007 Feb 6.PMID: 17279354 [PubMed - indexed for MEDLINE]Related articles

Large brachial and common carotid artery diameter in postmenopausal women with carotid atherosclerosis.

Montalcini T, Gorgone G, Gazzaruso C, Sesti G, Perticone F, Pujia A.

Atherosclerosis. 2008 Jan;196(1):443-8. Epub 2007 Jan 23.PMID: 17250840 [PubMed - indexed for MEDLINE]Related articles

Interleukin-6 impairs the insulin signaling pathway, promoting production of nitric oxide in human umbilical vein endothelial cells.

Andreozzi F, Laratta E, Procopio C, Hribal ML, Sciacqua A, Perticone M, Miele C, Perticone F, Sesti G.

Mol Cell Biol. 2007 Mar;27(6):2372-83. Epub 2007 Jan 22.PMID: 17242212 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of growth hormone and insulin-like growth factor-1 on cardiac hypertrophy of hypertensive patients.

Sesti G, Sciacqua A, Scozzafava A, Vatrano M, Angotti E, Ruberto C, Santillo E, Parlato G, Perticone F.

J Hypertens. 2007 Feb;25(2):471-7.PMID: 17211256 [PubMed - indexed for MEDLINE]Related articles

Endogenous testosterone and endothelial function in postmenopausal women.

Montalcini T, Gorgone G, Gazzaruso C, Sesti G, Perticone F, Pujia A.

Coron Artery Dis. 2007 Feb;18(1):9-13.PMID: 17172924 [PubMed - indexed for MEDLINE]Related articles

Pathophysiology of insulin resistance.

Sesti G.

Best Pract Res Clin Endocrinol Metab. 2006 Dec;20(4):665-79. Review.PMID: 17161338 [PubMed - indexed for MEDLINE]Related articles

Carotid atherosclerosis associated to metabolic syndrome but not BMI in healthy menopausal women.

Montalcini T, Gorgone G, Gazzaruso C, Sesti G, Perticone F, Pujia A.

Diabetes Res Clin Pract. 2007 Jun;76(3):378-82. Epub 2006 Oct 10.PMID: 17034893 [PubMed - indexed for MEDLINE]Related articles

The PEA15 gene is overexpressed and related to insulin resistance in healthy first-degree relatives of patients with type 2 diabetes.

Valentino R, Lupoli GA, Raciti GA, Oriente F, Farinaro E, Della Valle E, Salomone M, Riccardi G, Vaccaro O, Donnarumma G, Sesti G, Hribal ML, Cardellini M, Miele C, Formisano P, Beguinot F.

Diabetologia. 2006 Dec;49(12):3058-66. Epub 2006 Oct 5.PMID: 17021921 [PubMed - indexed for MEDLINE]Related articles

Carotid artery intima-media thickness is associated with insulin-mediated glucose disposal in nondiabetic normotensive offspring of type 2 diabetic patients.

Cardellini M, Marini MA, Frontoni S, Hribal ML, Andreozzi F, Perticone F, Federici M, Lauro D, Sesti G.

Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E347-52. Epub 2006 Sep 12.PMID: 16968812 [PubMed - indexed for MEDLINE]Related articlesFree article

Plasma interleukin-6 levels are increased in subjects with impaired glucose tolerance but not in those with impaired fasting glucose in a cohort of Italian Caucasians.

Cardellini M, Andreozzi F, Laratta E, Marini MA, Lauro R, Hribal ML, Perticone F, Sesti G.

Diabetes Metab Res Rev. 2007 Feb;23(2):141-5.PMID: 16952201 [PubMed - indexed for MEDLINE]Related articles

Plasma interleukin-6 levels are independently associated with insulin secretion in a cohort of Italian-Caucasian nondiabetic subjects.

Andreozzi F, Laratta E, Cardellini M, Marini MA, Lauro R, Hribal ML, Perticone F, Sesti G.

Diabetes. 2006 Jul;55(7):2021-4.PMID: 16804071 [PubMed - indexed for MEDLINE]Related articlesFree article