PubMed

Undernutrition of the GK rat during gestation improves pancreatic IGF-2 and beta-cell mass in the fetuses.

Fernández-Millán E, Gangnerau MN, De Miguel-Santos L, Calderari S, Serradas P, Escrivá F, Portha B, Alvarez C.

Growth Factors. 2009 Dec;27(6):409-18.PMID: 19919529 [PubMed - in process]Related articles

Undernutrition of the GK rat during gestation improves pancreatic IGF-2 and beta-cell mass in the fetuses.

Fernandez-Millan E, Gangnerau MN, De Miguel-Santos L, Calderari S, Serradas P, Escriva F, Portha B, Alvarez C.

Growth Factors. 2009 Aug 21:1. [Epub ahead of print]PMID: 19701837 [PubMed - as supplied by publisher]Related articles

Loss of sugar detection by GLUT2 affects glucose homeostasis in mice.

Stolarczyk E, Le Gall M, Even P, Houllier A, Serradas P, Brot-Laroche E, Leturque A.

PLoS One. 2007 Dec 12;2(12):e1288.PMID: 18074013 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin internalizes GLUT2 in the enterocytes of healthy but not insulin-resistant mice.

Tobin V, Le Gall M, Fioramonti X, Stolarczyk E, Blazquez AG, Klein C, Prigent M, Serradas P, Cuif MH, Magnan C, Leturque A, Brot-Laroche E.

Diabetes. 2008 Mar;57(3):555-62. Epub 2007 Dec 5.PMID: 18057092 [PubMed - indexed for MEDLINE]Related articlesFree article

Type 2 diabetes - a matter of failing beta-cell neogenesis? Clues from the GK rat model.

Movassat J, Calderari S, Fernández E, Martín MA, Escrivá F, Plachot C, Gangnerau MN, Serradas P, Alvarez C, Portha B.

Diabetes Obes Metab. 2007 Nov;9 Suppl 2:187-95. Review.PMID: 17919193 [PubMed - indexed for MEDLINE]Related articles

Defective IGF2 and IGF1R protein production in embryonic pancreas precedes beta cell mass anomaly in the Goto-Kakizaki rat model of type 2 diabetes.

Calderari S, Gangnerau MN, Thibault M, Meile MJ, Kassis N, Alvarez C, Portha B, Serradas P.

Diabetologia. 2007 Jul;50(7):1463-71. Epub 2007 May 3.PMID: 17476475 [PubMed - indexed for MEDLINE]Related articles

Is defective pancreatic beta-cell mass environmentally programmed in Goto-Kakizaki rat model of type 2 diabetes?: insights from crossbreeding studies during suckling period.

Calderari S, Gangnerau MN, Meile MJ, Portha B, Serradas P.

Pancreas. 2006 Nov;33(4):412-7.PMID: 17079948 [PubMed - indexed for MEDLINE]Related articles

Consequences of fetal exposure to maternal diabetes in offspring.

Fetita LS, Sobngwi E, Serradas P, Calvo F, Gautier JF.

J Clin Endocrinol Metab. 2006 Oct;91(10):3718-24. Epub 2006 Jul 18. Review.PMID: 16849402 [PubMed - indexed for MEDLINE]Related articlesFree article

Undernutrition does not alter the activation of beta-cell neogenesis and replication in adult rats after partial pancreatectomy.

Fernández E, Martín MA, Fajardo S, Bailbé D, Gangnerau MN, Portha B, Escrivá F, Serradas P, Alvarez C.

Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E913-21. Epub 2006 Jun 6.PMID: 16757552 [PubMed - indexed for MEDLINE]Related articlesFree article

Islet inflammation and fibrosis in a spontaneous model of type 2 diabetes, the GK rat.

Homo-Delarche F, Calderari S, Irminger JC, Gangnerau MN, Coulaud J, Rickenbach K, Dolz M, Halban P, Portha B, Serradas P.

Diabetes. 2006 Jun;55(6):1625-33. Erratum in: Diabetes. 2006 Sep;55(9):2665. PMID: 16731824 [PubMed - indexed for MEDLINE]Related articlesFree article

Restitution of defective glucose-stimulated insulin secretion in diabetic GK rat by acetylcholine uncovers paradoxical stimulatory effect of beta-cell muscarinic receptor activation on cAMP production.

Dolz M, Bailbé D, Giroix MH, Calderari S, Gangnerau MN, Serradas P, Rickenbach K, Irminger JC, Portha B.

Diabetes. 2005 Nov;54(11):3229-37.PMID: 16249449 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein-caloric food restriction affects insulin-like growth factor system in fetal Wistar rat.

Martín MA, Serradas P, Ramos S, Fernández E, Goya L, Gangnerau MN, Lacorne M, Pascual-Leone AM, Escrivá F, Portha B, Alvarez C.

Endocrinology. 2005 Mar;146(3):1364-71. Epub 2004 Dec 2.PMID: 15576465 [PubMed - indexed for MEDLINE]Related articlesFree article

Fetal insulin-like growth factor-2 production is impaired in the GK rat model of type 2 diabetes.

Serradas P, Goya L, Lacorne M, Gangnerau MN, Ramos S, Alvarez C, Pascual-Leone AM, Portha B.

Diabetes. 2002 Feb;51(2):392-7.PMID: 11812746 [PubMed - indexed for MEDLINE]Related articlesFree article

beta-cell function and viability in the spontaneously diabetic GK rat: information from the GK/Par colony.

Portha B, Giroix MH, Serradas P, Gangnerau MN, Movassat J, Rajas F, Bailbe D, Plachot C, Mithieux G, Marie JC.

Diabetes. 2001 Feb;50 Suppl 1:S89-93.PMID: 11272210 [PubMed - indexed for MEDLINE]Related articles

Effect of gliclazide treatment on insulin secretion and beta-cell mass in non-insulin dependent diabetic Goto-Kakisaki rats.

Dachicourt N, Bailbé D, Gangnerau MN, Serradas P, Ravel D, Portha B.

Eur J Pharmacol. 1998 Nov 20;361(2-3):243-51.PMID: 9865514 [PubMed - indexed for MEDLINE]Related articles

Specific inhibition of GLUT2 in arcuate nucleus by antisense oligonucleotides suppresses nervous control of insulin secretion.

Leloup C, Orosco M, Serradas P, Nicolaïdis S, Pénicaud L.

Brain Res Mol Brain Res. 1998 Jun 15;57(2):275-80.PMID: 9675426 [PubMed - indexed for MEDLINE]Related articles

Impaired pancreatic beta cell function in the fetal GK rat. Impact of diabetic inheritance.

Serradas P, Gangnerau MN, Giroix MH, Saulnier C, Portha B.

J Clin Invest. 1998 Feb 15;101(4):899-904.PMID: 9466985 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucagon-like peptide-1(7-36)-amide confers glucose sensitivity to previously glucose-incompetent beta-cells in diabetic rats: in vivo and in vitro studies.

Dachicourt N, Serradas P, Bailbé D, Kergoat M, Doaré L, Portha B.

J Endocrinol. 1997 Nov;155(2):369-76.PMID: 9415071 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired development of pancreatic beta-cell mass is a primary event during the progression to diabetes in the GK rat.

Movassat J, Saulnier C, Serradas P, Portha B.

Diabetologia. 1997 Aug;40(8):916-25.PMID: 9267986 [PubMed - indexed for MEDLINE]Related articles

Genetic analyses of glucose transporter genes in French non-insulin-dependent diabetic families.

Lesage S, Zouali H, Vionnet N, Philippi A, Velho G, Serradas P, Passa P, Demenais F, Froguel P.

Diabetes Metab. 1997 Apr;23(2):137-42.PMID: 9137902 [PubMed - indexed for MEDLINE]Related articlesFree article

Transplantation of syngenic pancreatic islets into rats with streptozotocin induced non insulin dependent diabetes mellitus.

Tormo MA, Bailbé D, Serradas P, Saulnier C, Portha B, Campillo JE.

Adv Exp Med Biol. 1997;426:441-5. No abstract available. PMID: 9544304 [PubMed - indexed for MEDLINE]Related articles

Insulin secretion and glucose tolerance after islet transplantation in rats with noninsulin-dependent diabetes induced by neonatal streptozotocin.

Tormo MA, Leon-Quinto T, Saulnier C, Bailbe D, Serradas P, Portha B.

Cell Transplant. 1997 Jan-Feb;6(1):23-32.PMID: 9040952 [PubMed - indexed for MEDLINE]Related articles

Decreased glucose-induced cAMP and insulin release in islets of diabetic rats: reversal by IBMX, glucagon, GIP.

Dachicourt N, Serradas P, Giroix MH, Gangnerau MN, Portha B.

Am J Physiol. 1996 Oct;271(4 Pt 1):E725-32.PMID: 8897861 [PubMed - indexed for MEDLINE]Related articles

Mitochondrial deoxyribonucleic acid content is specifically decreased in adult, but not fetal, pancreatic islets of the Goto-Kakizaki rat, a genetic model of noninsulin-dependent diabetes.

Serradas P, Giroix MH, Saulnier C, Gangnerau MN, Borg LA, Welsh M, Portha B, Welsh N.

Endocrinology. 1995 Dec;136(12):5623-31.PMID: 7588317 [PubMed - indexed for MEDLINE]Related articles

Glucose refractoriness of pancreatic beta-cells in rat models of non-insulin dependent diabetes.

Portha B, Giroix MH, Serradas P, Morin L, Saulnier C, Bailbe D.

Diabete Metab. 1994 Mar-Apr;20(2):108-15.PMID: 7805948 [PubMed - indexed for MEDLINE]Related articles

Effect of benfluorex on insulin secretion and insulin action in streptozotocin-diabetic rats.

Portha B, Serradas P, Bailbé D, Blondel O, Picarel F.

Diabetes Metab Rev. 1993 Nov;9 Suppl 1:57S-63S.PMID: 8299491 [PubMed - indexed for MEDLINE]Related articles

Benfluorex normalizes hyperglycemia and reverses hepatic insulin resistance in STZ-induced diabetic rats.

Serradas P, Blondel O, Bailbe D, Portha B.

Diabetes. 1993 Apr;42(4):564-70.PMID: 8454107 [PubMed - indexed for MEDLINE]Related articles

Improvement in glucose-induced insulin secretion in diabetic rats after long-term gliclazide treatment: a comparative study using different models of non-insulin-dependent diabetes mellitus induced by neonatal streptozotocin.

Portha B, Serradas P.

Am J Med. 1991 Jun 24;90(6A):15S-21S.PMID: 1831320 [PubMed - indexed for MEDLINE]Related articles

Beta-cell insensitivity to glucose in the GK rat, a spontaneous nonobese model for type II diabetes.

Portha B, Serradas P, Bailbé D, Suzuki K, Goto Y, Giroix MH.

Diabetes. 1991 Apr;40(4):486-91.PMID: 2010050 [PubMed - indexed for MEDLINE]Related articles

Abnormal B-cell function in rats with non-insulin-dependent diabetes induced by neonatal streptozotocin: effect of in vivo insulin, phlorizin, or vanadate treatments.

Serradas P, Bailbé D, Blondel O, Portha B.

Pancreas. 1991 Jan;6(1):54-62.PMID: 1994380 [PubMed - indexed for MEDLINE]Related articles

The desensitization of normal B-cells to glucose in vitro is transient and not related to high glucose levels.

Giroix MH, Serradas P, Portha B.

Endocrinology. 1989 Oct;125(4):1999-2007.PMID: 2676476 [PubMed - indexed for MEDLINE]Related articles

Long-term gliclazide treatment improves the in vitro glucose-induced insulin release in rats with type 2 (non-insulin-dependent) diabetes induced by neonatal streptozotocin.

Serradas P, Bailbé D, Portha B.

Diabetologia. 1989 Aug;32(8):577-84.PMID: 2528491 [PubMed - indexed for MEDLINE]Related articles

The rat models of non-insulin dependent diabetes induced by neonatal streptozotocin.

Portha B, Blondel O, Serradas P, McEvoy R, Giroix MH, Kergoat M, Bailbe D.

Diabete Metab. 1989 Mar-Apr;15(2):61-75. Review.PMID: 2525491 [PubMed - indexed for MEDLINE]Related articles

Evaluation of the pancreatic B-cell function in the rat after prenatal exposure to streptozotocin or N-nitrosomethylurea.

Serradas P, Giroix MH, Portha B.

Diabete Metab. 1989 Jan-Feb;15(1):30-7.PMID: 2524413 [PubMed - indexed for MEDLINE]Related articles

Insulin production and glucose metabolism in isolated pancreatic islets of rats with NIDDM.

Portha B, Giroix MH, Serradas P, Welsh N, Hellerström C, Sener A, Malaisse WJ.

Diabetes. 1988 Sep;37(9):1226-33.PMID: 3044888 [PubMed - indexed for MEDLINE]Related articles

[Animal models of non-insulin-dependent diabetes induced in the rat by experimental reduction of B cell mass]

Portha B, Giroix MH, Kergoat M, Bailbe D, Blondel O, Serradas P.

Journ Annu Diabetol Hotel Dieu. 1988:33-46. Review. French. No abstract available. PMID: 2971833 [PubMed - indexed for MEDLINE]Related articles