PubMed

Hepatocyte-like cells derived from human embryonic stem cells specifically via definitive endoderm and a progenitor stage.

Brolén G, Sivertsson L, Björquist P, Eriksson G, Ek M, Semb H, Johansson I, Andersson TB, Ingelman-Sundberg M, Heins N.

J Biotechnol. 2009 Nov 19. [Epub ahead of print]PMID: 19932139 [PubMed - as supplied by publisher]Related articles

Cdc42-mediated tubulogenesis controls cell specification.

Kesavan G, Sand FW, Greiner TU, Johansson JK, Kobberup S, Wu X, Brakebusch C, Semb H.

Cell. 2009 Nov 13;139(4):791-801.PMID: 19914171 [PubMed - in process]Related articles

FGF2 Specifies hESC-Derived Definitive Endoderm into Foregut/Midgut Cell Lineages in a Concentration-Dependent Manner.

Ameri J, Ståhlberg A, Pedersen J, Johansson JK, Johannesson MM, Artner I, Semb H.

Stem Cells. 2009 Nov 3. [Epub ahead of print]PMID: 19890880 [PubMed - as supplied by publisher]Related articles

Quantitative transcription factor analysis of undifferentiated single human embryonic stem cells.

Ståhlberg A, Bengtsson M, Hemberg M, Semb H.

Clin Chem. 2009 Dec;55(12):2162-70. Epub 2009 Oct 8.PMID: 19815608 [PubMed - in process]Related articles

FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner.

Johannesson M, Ståhlberg A, Ameri J, Sand FW, Norrman K, Semb H.

PLoS One. 2009;4(3):e4794. Epub 2009 Mar 11.PMID: 19277121 [PubMed - indexed for MEDLINE]Related articlesFree article

Impaired insulin exocytosis in neural cell adhesion molecule-/- mice due to defective reorganization of the submembrane F-actin network.

Olofsson CS, Håkansson J, Salehi A, Bengtsson M, Galvanovskis J, Partridge C, SörhedeWinzell M, Xian X, Eliasson L, Lundquist I, Semb H, Rorsman P.

Endocrinology. 2009 Jul;150(7):3067-75. Epub 2009 Feb 12.PMID: 19213846 [PubMed - indexed for MEDLINE]Related articles

Rac1 regulates pancreatic islet morphogenesis.

Greiner TU, Kesavan G, Ståhlberg A, Semb H.

BMC Dev Biol. 2009 Jan 6;9:2.PMID: 19126201 [PubMed - indexed for MEDLINE]Related articlesFree article

Expandable endodermal progenitors: new tools to explore endoderm and its derivatives.

Semb H.

Cell Stem Cell. 2008 Oct 9;3(4):355-6.PMID: 18940723 [PubMed - indexed for MEDLINE]Related articles

The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response.

Andersson MK, Ståhlberg A, Arvidsson Y, Olofsson A, Semb H, Stenman G, Nilsson O, Aman P.

BMC Cell Biol. 2008 Jul 11;9:37.PMID: 18620564 [PubMed - indexed for MEDLINE]Related articlesFree article

Definitive endoderm: a key step in coaxing human embryonic stem cells into transplantable beta-cells.

Semb H.

Biochem Soc Trans. 2008 Jun;36(Pt 3):272-5. Review.PMID: 18481940 [PubMed - indexed for MEDLINE]Related articles

Pericytes: gatekeepers in tumour cell metastasis?

Gerhardt H, Semb H.

J Mol Med. 2008 Feb;86(2):135-44. Epub 2007 Sep 22. Review.PMID: 17891366 [PubMed - indexed for MEDLINE]Related articles

Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.

International Stem Cell Initiative, Adewumi O, Aflatoonian B, Ahrlund-Richter L, Amit M, Andrews PW, Beighton G, Bello PA, Benvenisty N, Berry LS, Bevan S, Blum B, Brooking J, Chen KG, Choo AB, Churchill GA, Corbel M, Damjanov I, Draper JS, Dvorak P, Emanuelsson K, Fleck RA, Ford A, Gertow K, Gertsenstein M, Gokhale PJ, Hamilton RS, Hampl A, Healy LE, Hovatta O, Hyllner J, Imreh MP, Itskovitz-Eldor J, Jackson J, Johnson JL, Jones M, Kee K, King BL, Knowles BB, Lako M, Lebrin F, Mallon BS, Manning D, Mayshar Y, McKay RD, Michalska AE, Mikkola M, Mileikovsky M, Minger SL, Moore HD, Mummery CL, Nagy A, Nakatsuji N, O'Brien CM, Oh SK, Olsson C, Otonkoski T, Park KY, Passier R, Patel H, Patel M, Pedersen R, Pera MF, Piekarczyk MS, Pera RA, Reubinoff BE, Robins AJ, Rossant J, Rugg-Gunn P, Schulz TC, Semb H, Sherrer ES, Siemen H, Stacey GN, Stojkovic M, Suemori H, Szatkiewicz J, Turetsky T, Tuuri T, van den Brink S, Vintersten K, Vuoristo S, Ward D, Weaver TA, Young LA, Zhang W.

Nat Biotechnol. 2007 Jul;25(7):803-16. Epub 2007 Jun 17.PMID: 17572666 [PubMed - indexed for MEDLINE]Related articles

Facilitated expansion of human embryonic stem cells by single-cell enzymatic dissociation.

Ellerström C, Strehl R, Noaksson K, Hyllner J, Semb H.

Stem Cells. 2007 Jul;25(7):1690-6. Epub 2007 Mar 22.PMID: 17379766 [PubMed - indexed for MEDLINE]Related articlesFree article

Tumor progression induced by the loss of E-cadherin independent of beta-catenin/Tcf-mediated Wnt signaling.

Herzig M, Savarese F, Novatchkova M, Semb H, Christofori G.

Oncogene. 2007 Apr 5;26(16):2290-8. Epub 2006 Oct 9.PMID: 17043652 [PubMed - indexed for MEDLINE]Related articles

Derivation of a xeno-free human embryonic stem cell line.

Ellerström C, Strehl R, Moya K, Andersson K, Bergh C, Lundin K, Hyllner J, Semb H.

Stem Cells. 2006 Oct;24(10):2170-6. Epub 2006 Jun 1.PMID: 16741223 [PubMed - indexed for MEDLINE]Related articlesFree article

Elimination of damaged proteins during differentiation of embryonic stem cells.

Hernebring M, Brolén G, Aguilaniu H, Semb H, Nyström T.

Proc Natl Acad Sci U S A. 2006 May 16;103(20):7700-5. Epub 2006 May 3.PMID: 16672370 [PubMed - indexed for MEDLINE]Related articlesFree article

Human embryonic stem cells: origin, properties and applications.

Semb H.

APMIS. 2005 Nov-Dec;113(11-12):743-50. Review.PMID: 16480446 [PubMed - indexed for MEDLINE]Related articles

Pericytes limit tumor cell metastasis.

Xian X, Håkansson J, Ståhlberg A, Lindblom P, Betsholtz C, Gerhardt H, Semb H.

J Clin Invest. 2006 Mar;116(3):642-51. Epub 2006 Feb 9.PMID: 16470244 [PubMed - indexed for MEDLINE]Related articlesFree article

Clonal derivation and characterization of human embryonic stem cell lines.

Heins N, Lindahl A, Karlsson U, Rehnström M, Caisander G, Emanuelsson K, Hanson C, Semb H, Björquist P, Sartipy P, Hyllner J.

J Biotechnol. 2006 Apr 20;122(4):511-20. Epub 2005 Dec 1.PMID: 16324761 [PubMed - indexed for MEDLINE]Related articles

Signals from the embryonic mouse pancreas induce differentiation of human embryonic stem cells into insulin-producing beta-cell-like cells.

Brolén GK, Heins N, Edsbagge J, Semb H.

Diabetes. 2005 Oct;54(10):2867-74.PMID: 16186387 [PubMed - indexed for MEDLINE]Related articlesFree article

Monitoring differentiation of human embryonic stem cells using real-time PCR.

Noaksson K, Zoric N, Zeng X, Rao MS, Hyllner J, Semb H, Kubista M, Sartipy P.

Stem Cells. 2005 Nov-Dec;23(10):1460-7. Epub 2005 Aug 4.PMID: 16081663 [PubMed - indexed for MEDLINE]Related articlesFree article

The International Stem Cell Initiative: toward benchmarks for human embryonic stem cell research.

Andrews PW, Benvenisty N, McKay R, Pera MF, Rossant J, Semb H, Stacey GN; Steering Committee of the International Stem Cell Initiative.

Nat Biotechnol. 2005 Jul;23(7):795-7. No abstract available. PMID: 16003358 [PubMed - indexed for MEDLINE]Related articles

Neural cell adhesion molecule-deficient beta-cell tumorigenesis results in diminished extracellular matrix molecule expression and tumour cell-matrix adhesion.

Håkansson J, Xian X, He L, Ståhlberg A, Nelander S, Samuelsson T, Kubista M, Semb H.

Tumour Biol. 2005 Mar-Apr;26(2):103-12.PMID: 15897690 [PubMed - indexed for MEDLINE]Related articles

Vascular function and sphingosine-1-phosphate regulate development of the dorsal pancreatic mesenchyme.

Edsbagge J, Johansson JK, Esni F, Luo Y, Radice GL, Semb H.

Development. 2005 Mar;132(5):1085-92. Epub 2005 Feb 2.PMID: 15689381 [PubMed - indexed for MEDLINE]Related articlesFree article

Artifactual insulin release from differentiated embryonic stem cells.

Hansson M, Tonning A, Frandsen U, Petri A, Rajagopal J, Englund MC, Heller RS, Håkansson J, Fleckner J, Sköld HN, Melton D, Semb H, Serup P.

Diabetes. 2004 Oct;53(10):2603-9.PMID: 15448090 [PubMed - indexed for MEDLINE]Related articlesFree article

Human blastocysts for the development of embryonic stem cells.

Sjögren A, Hardarson T, Andersson K, Caisander G, Lundquist M, Wikland M, Semb H, Hamberger L.

Reprod Biomed Online. 2004 Sep;9(3):326-9.PMID: 15353085 [PubMed - indexed for MEDLINE]Related articles

Derivation, characterization, and differentiation of human embryonic stem cells.

Heins N, Englund MC, Sjöblom C, Dahl U, Tonning A, Bergh C, Lindahl A, Hanson C, Semb H.

Stem Cells. 2004;22(3):367-76.PMID: 15153613 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of dominant negative cadherin in the adult mouse brain modifies rearing behavior.

Edsbagge J, Zhu S, Xiao MY, Wigström H, Mohammed AH, Semb H.

Mol Cell Neurosci. 2004 Mar;25(3):524-35.PMID: 15033180 [PubMed - indexed for MEDLINE]Related articles

Properties of the reverse transcription reaction in mRNA quantification.

Ståhlberg A, Håkansson J, Xian X, Semb H, Kubista M.

Clin Chem. 2004 Mar;50(3):509-15. Epub 2004 Jan 15.PMID: 14726469 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of classical cadherins in thyroid development: maintenance of an epithelial phenotype throughout organogenesis.

Fagman H, Grände M, Edsbagge J, Semb H, Nilsson M.

Endocrinology. 2003 Aug;144(8):3618-24.PMID: 12865344 [PubMed - indexed for MEDLINE]Related articlesFree article

Genetic dissection of cadherin function during nephrogenesis.

Dahl U, Sjödin A, Larue L, Radice GL, Cajander S, Takeichi M, Kemler R, Semb H.

Mol Cell Biol. 2002 Mar;22(5):1474-87.PMID: 11839813 [PubMed - indexed for MEDLINE]Related articlesFree article

Dorsal pancreas agenesis in N-cadherin- deficient mice.

Esni F, Johansson BR, Radice GL, Semb H.

Dev Biol. 2001 Oct 1;238(1):202-12.PMID: 11784004 [PubMed - indexed for MEDLINE]Related articles

The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene.

Christofori G, Semb H.

Trends Biochem Sci. 1999 Feb;24(2):73-6. Review.PMID: 10098402 [PubMed - indexed for MEDLINE]Related articles

Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic beta tumor cells.

Perl AK, Dahl U, Wilgenbus P, Cremer H, Semb H, Christofori G.

Nat Med. 1999 Mar;5(3):286-91.PMID: 10086383 [PubMed - indexed for MEDLINE]Related articles

Odor identification in normal aging and early Alzheimer's disease: effects of retrieval support.

Larsson M, Semb H, Winblad B, Amberla K, Wahlund LO, Bäckman L.

Neuropsychology. 1999 Jan;13(1):47-53.PMID: 10067775 [PubMed - indexed for MEDLINE]Related articles

Neural cell adhesion molecule (N-CAM) is required for cell type segregation and normal ultrastructure in pancreatic islets.

Esni F, Täljedal IB, Perl AK, Cremer H, Christofori G, Semb H.

J Cell Biol. 1999 Jan 25;144(2):325-37.PMID: 9922458 [PubMed - indexed for MEDLINE]Related articlesFree article

The tumor-suppressor function of E-cadherin.

Semb H, Christofori G.

Am J Hum Genet. 1998 Dec;63(6):1588-93. Review. No abstract available. PMID: 9837810 [PubMed - indexed for MEDLINE]Related articlesFree article

A causal role for E-cadherin in the transition from adenoma to carcinoma.

Perl AK, Wilgenbus P, Dahl U, Semb H, Christofori G.

Nature. 1998 Mar 12;392(6672):190-3.PMID: 9515965 [PubMed - indexed for MEDLINE]Related articles

A potential role of R-cadherin in striated muscle formation.

Rosenberg P, Esni F, Sjödin A, Larue L, Carlsson L, Gullberg D, Takeichi M, Kemler R, Semb H.

Dev Biol. 1997 Jul 1;187(1):55-70.PMID: 9224674 [PubMed - indexed for MEDLINE]Related articles

Effects of divalent cations on M-cadherin expression and distribution during primary rat myogenesis in vitro.

Eng H, Herrenknecht K, Semb H, Starzinski-Powitz A, Ringertz N, Gullberg D.

Differentiation. 1997 Feb;61(3):169-76.PMID: 9084135 [PubMed - indexed for MEDLINE]Related articles

Cadherins regulate aggregation of pancreatic beta-cells in vivo.

Dahl U, Sjødin A, Semb H.

Development. 1996 Sep;122(9):2895-902.PMID: 8787762 [PubMed - indexed for MEDLINE]Related articlesFree article

Mouse R-cadherin: expression during the organogenesis of pancreas and gastrointestinal tract.

Sjödin A, Dahl U, Semb H.

Exp Cell Res. 1995 Dec;221(2):413-25.PMID: 7493641 [PubMed - indexed for MEDLINE]Related articles

Renal function not impaired by hip arthroplasty. A prospective study of 26 patients.

Stegmayr BG, Björck L, Kempi V, Semb H.

Acta Orthop Scand. 1992 Feb;63(1):7-12.PMID: 1738976 [PubMed - indexed for MEDLINE]Related articles

Hyperlipoproteinemia type I in a patient with active lipoprotein lipase in adipose tissue and indications of defective transport of the enzyme.

Fager G, Semb H, Enerbäck S, Olivecrona T, Jonasson L, Bengtsson-Olivecrona G, Camejo G, Bjursell G, Bondjers G.

J Lipid Res. 1990 Jul;31(7):1187-97.PMID: 2205700 [PubMed - indexed for MEDLINE]Related articlesFree article

Two different mechanisms are involved in nutritional regulation of lipoprotein lipase in guinea-pig adipose tissue.

Semb H, Olivecrona T.

Biochem J. 1989 Sep 1;262(2):505-11.PMID: 2803266 [PubMed - indexed for MEDLINE]Related articlesFree article

The relation between glycosylation and activity of guinea pig lipoprotein lipase.

Semb H, Olivecrona T.

J Biol Chem. 1989 Mar 5;264(7):4195-200.PMID: 2521859 [PubMed - indexed for MEDLINE]Related articlesFree article

Tissue-specific regulation of guinea pig lipoprotein lipase; effects of nutritional state and of tumor necrosis factor on mRNA levels in adipose tissue, heart and liver.

Enerbäck S, Semb H, Tavernier J, Bjursell G, Olivecrona T.

Gene. 1988 Apr 15;64(1):97-106.PMID: 3396878 [PubMed - indexed for MEDLINE]Related articles

Mechanisms for turnover of lipoprotein lipase in guinea pig adipocytes.

Semb H, Olivecrona T.

Biochim Biophys Acta. 1987 Sep 4;921(1):104-15.PMID: 3620483 [PubMed - indexed for MEDLINE]Related articles

Multiple effects of tumor necrosis factor on lipoprotein lipase in vivo.

Semb H, Peterson J, Tavernier J, Olivecrona T.

J Biol Chem. 1987 Jun 15;262(17):8390-4.PMID: 3597377 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular cloning and sequence analysis of cDNA encoding lipoprotein lipase of guinea pig.

Enerbäck S, Semb H, Bengtsson-Olivecrona G, Carlsson P, Hermansson ML, Olivecrona T, Bjursell G.

Gene. 1987;58(1):1-12.PMID: 3692172 [PubMed - indexed for MEDLINE]Related articles