PubMed

A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis.

Mero IL, Lorentzen AR, Ban M, Smestad C, Celius EG, Aarseth JH, Myhr KM, Link J, Hillert J, Olsson T, Kockum I, Masterman T, Oturai AB, Søndergaard HB, Sellebjerg F, Saarela J, Kemppinen A, Elovaara I, Spurkland A, Dudbridge F, Lie BA, Harbo HF.

Eur J Hum Genet. 2009 Nov 4. [Epub ahead of print]PMID: 19888296 [PubMed - as supplied by publisher]Related articles

Absence of MxA induction by interferon beta in patients with MS reflects complete loss of bioactivity.

Hesse D, Sellebjerg F, Sorensen PS.

Neurology. 2009 Aug 4;73(5):372-7.PMID: 19652141 [PubMed - indexed for MEDLINE]Related articles

Identification of new sensitive biomarkers for the in vivo response to interferon-beta treatment in multiple sclerosis using DNA-array evaluation.

Sellebjerg F, Krakauer M, Hesse D, Ryder LP, Alsing I, Jensen PE, Koch-Henriksen N, Svejgaard A, Soelberg Sørensen P.

Eur J Neurol. 2009 Jun 22. [Epub ahead of print]PMID: 19558503 [PubMed - as supplied by publisher]Related articles

EFNS guidelines on disease-specific CSF investigations.

Deisenhammer F, Egg R, Giovannoni G, Hemmer B, Petzold A, Sellebjerg F, Teunissen C, Tumani H; EFSN.

Eur J Neurol. 2009 Jun;16(6):760-70.PMID: 19475759 [PubMed - indexed for MEDLINE]Related articles

Efficacy of natalizumab in multiple sclerosis patients with high disease activity: a Danish nationwide study.

Oturai AB, Koch-Henriksen N, Petersen T, Jensen PE, Sellebjerg F, Sorensen PS.

Eur J Neurol. 2009 Mar;16(3):420-3.PMID: 19364368 [PubMed - indexed for MEDLINE]Related articles

The effects of natalizumab on inflammatory mediators in multiple sclerosis: prospects for treatment-sensitive biomarkers.

Khademi M, Bornsen L, Rafatnia F, Andersson M, Brundin L, Piehl F, Sellebjerg F, Olsson T.

Eur J Neurol. 2009 Apr;16(4):528-36.PMID: 19220425 [PubMed - indexed for MEDLINE]Related articles

Autoantibodies to myelin basic protein (MBP) in healthy individuals and in patients with multiple sclerosis: a role in regulating cytokine responses to MBP.

Hedegaard CJ, Chen N, Sellebjerg F, Sørensen PS, Leslie RG, Bendtzen K, Nielsen CH.

Immunology. 2009 Sep;128(1 Suppl):e451-61. Epub 2008 Dec 18.PMID: 19191913 [PubMed - in process]Related articles

Methylprednisolone does not restore biological response in multiple sclerosis patients with neutralizing antibodies against interferon-beta.

Hesse D, Frederiksen JL, Koch-Henriksen N, Schreiber K, Stenager E, Heltberg A, Ravnborg M, Bendtzen K, Sellebjerg F, Sorensen PS.

Eur J Neurol. 2009 Jan;16(1):43-7.PMID: 19087149 [PubMed - in process]Related articles

Oral fumarate for relapsing-remitting multiple sclerosis.

Sorensen PS, Sellebjerg F.

Lancet. 2008 Oct 25;372(9648):1447-8. No abstract available. PMID: 18970966 [PubMed - indexed for MEDLINE]Related articles

The effect of beta-interferon therapy on myelin basic protein-elicited CD4+ T cell proliferation and cytokine production in multiple sclerosis.

Hedegaard CJ, Krakauer M, Bendtzen K, Sørensen PS, Sellebjerg F, Nielsen CH.

Clin Immunol. 2008 Oct;129(1):80-9. Epub 2008 Jul 23.PMID: 18653385 [PubMed - indexed for MEDLINE]Related articles

[Biological treatment of multiple sclerosis]

Sørensen PS, Sellebjerg F.

Ugeskr Laeger. 2008 Jun 9;170(24):2156-9. Danish. PMID: 18565303 [PubMed - indexed for MEDLINE]Related articles

Increased IL-10 mRNA and IL-23 mRNA expression in multiple sclerosis: interferon-beta treatment increases IL-10 mRNA expression while reducing IL-23 mRNA expression.

Krakauer M, Sorensen P, Khademi M, Olsson T, Sellebjerg F.

Mult Scler. 2008 Jun;14(5):622-30. Epub 2008 Apr 18.PMID: 18424480 [PubMed - indexed for MEDLINE]Related articles

Gene expression analysis of interferon-beta treatment in multiple sclerosis.

Sellebjerg F, Datta P, Larsen J, Rieneck K, Alsing I, Oturai A, Svejgaard A, Soelberg Sørensen P, Ryder LP.

Mult Scler. 2008 Jun;14(5):615-21. Epub 2008 Apr 11.PMID: 18408020 [PubMed - indexed for MEDLINE]Related articles

[Multiple sclerosis--the significance of genes. The Danish Society of Neurology]

Sellebjerg F, Oturai A, Sørensen PS; Dansk Neurologisk Selskab.

Ugeskr Laeger. 2008 Mar 17;170(12):1046. Danish. No abstract available. PMID: 18397664 [PubMed - indexed for MEDLINE]Related articles

T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosis.

Hedegaard CJ, Krakauer M, Bendtzen K, Lund H, Sellebjerg F, Nielsen CH.

Immunology. 2008 Oct;125(2):161-9. Epub 2008 Apr 4. Erratum in: Immunology. 2008 Nov;125(3):438. PMID: 18397264 [PubMed - indexed for MEDLINE]Related articlesFree article

Chemokine receptor CCR5 in interferon-treated multiple sclerosis.

Sellebjerg F, Kristiansen TB, Wittenhagen P, Garred P, Eugen-Olsen J, Frederiksen JL, Sørensen TL.

Acta Neurol Scand. 2007 Jun;115(6):413-8.PMID: 17511851 [PubMed - indexed for MEDLINE]Related articles

Neutralising antibodies to interferon beta in multiple sclerosis : expert panel report.

Hartung HP, Polman C, Bertolotto A, Deisenhammer F, Giovannoni G, Havrdova E, Hemmer B, Hillert J, Kappos L, Kieseier B, Killestein J, Malcus C, Comabella M, Pachner A, Schellekens H, Sellebjerg F, Selmaj K, Sorensen PS.

J Neurol. 2007 Jul;254(7):827-37. Epub 2007 Apr 24. Review.PMID: 17457510 [PubMed - indexed for MEDLINE]Related articles

[Treatment of multiple sclerosis--now and in future. The Danish Multiple Sclerosis Society and the Danish Multiple Sclerosis Group]

Sellebjerg FT, Sørensen PS; Dansk Selskab for Forskning i Multipel Sclerose og Dansk Multipel Sclerose Gruppe.

Ugeskr Laeger. 2007 Mar 19;169(12):1121. Danish. No abstract available. PMID: 17394832 [PubMed - indexed for MEDLINE]Related articles

Tetranectin in cerebrospinal fluid of patients with multiple sclerosis.

Stoevring B, Jaliashvili I, Thougaard AV, Ensinger C, Høgdall CK, Rasmussen LS, Sellebjerg F, Christiansen M.

Scand J Clin Lab Invest. 2006;66(7):577-83.PMID: 17101549 [PubMed - indexed for MEDLINE]Related articles

CD4(+) memory T cells with high CD26 surface expression are enriched for Th1 markers and correlate with clinical severity of multiple sclerosis.

Krakauer M, Sorensen PS, Sellebjerg F.

J Neuroimmunol. 2006 Dec;181(1-2):157-64. Epub 2006 Nov 1.PMID: 17081623 [PubMed - indexed for MEDLINE]Related articles

Guidelines on routine cerebrospinal fluid analysis. Report from an EFNS task force.

Deisenhammer F, Bartos A, Egg R, Gilhus NE, Giovannoni G, Rauer S, Sellebjerg F; EFNS Task Force.

Eur J Neurol. 2006 Sep;13(9):913-22.PMID: 16930354 [PubMed - indexed for MEDLINE]Related articles

CD8+ T cell activation correlates with disease activity in clinically isolated syndromes and is regulated by interferon-beta treatment.

Jensen J, Langkilde AR, Frederiksen JL, Sellebjerg F.

J Neuroimmunol. 2006 Oct;179(1-2):163-72. Epub 2006 Aug 21.PMID: 16919783 [PubMed - indexed for MEDLINE]Related articles

Dynamic T-lymphocyte chemokine receptor expression induced by interferon-beta therapy in multiple sclerosis.

Krakauer M, Sorensen PS, Khademi M, Olsson T, Sellebjerg F.

Scand J Immunol. 2006 Aug;64(2):155-63.PMID: 16867161 [PubMed - indexed for MEDLINE]Related articles

EFNS guideline on treatment of multiple sclerosis relapses: report of an EFNS task force on treatment of multiple sclerosis relapses.

Sellebjerg F, Barnes D, Filippini G, Midgard R, Montalban X, Rieckmann P, Selmaj K, Visser LH, Sørensen PS; EFNS Task Force on Treatment of Multiple Sclerosis Relapses.

Eur J Neurol. 2005 Dec;12(12):939-46.PMID: 16324087 [PubMed - indexed for MEDLINE]Related articles

CD26 + CD4 + T cell counts and attack risk in interferon-treated multiple sclerosis.

Sellebjerg F, Ross C, Koch-Henriksen N, Sørensen PS, Frederiksen JL, Bendtzen K, Sørensen TL.

Mult Scler. 2005 Dec;11(6):641-5.PMID: 16320722 [PubMed - indexed for MEDLINE]Related articles

Acute axonal damage predicts clinical outcome in patients with multiple sclerosis.

Lim ET, Sellebjerg F, Jensen CV, Altmann DR, Grant D, Keir G, Thompson EJ, Giovannoni G.

Mult Scler. 2005 Oct;11(5):532-6.PMID: 16193890 [PubMed - indexed for MEDLINE]Related articles

Methylprednisolone treatment, immune activation, and intrathecal inflammation in multiple sclerosis.

Sellebjerg F.

Dan Med Bull. 2004 May;51(2):167-83. Review. No abstract available. PMID: 16009055 [PubMed - indexed for MEDLINE]Related articles

Recommended standard of cerebrospinal fluid analysis in the diagnosis of multiple sclerosis: a consensus statement.

Freedman MS, Thompson EJ, Deisenhammer F, Giovannoni G, Grimsley G, Keir G, Ohman S, Racke MK, Sharief M, Sindic CJ, Sellebjerg F, Tourtellotte WW.

Arch Neurol. 2005 Jun;62(6):865-70.PMID: 15956157 [PubMed - indexed for MEDLINE]Related articlesFree article

Tetranectin in cerebrospinal fluid: biochemical characterisation and evidence of intrathecal synthesis or selective uptake into CSF.

Stoevring B, Jaliashvili I, Thougaard AV, Ensinger C, Høgdall CK, Rasmussen LS, Sellebjerg F, Christiansen M.

Clin Chim Acta. 2005 Sep;359(1-2):65-71.PMID: 15901484 [PubMed - indexed for MEDLINE]Related articles

Systemic T-cell activation in acute clinically isolated optic neuritis.

Roed H, Frederiksen J, Langkilde A, Sørensen TL, Lauritzen M, Sellebjerg F.

J Neuroimmunol. 2005 May;162(1-2):165-72.PMID: 15833372 [PubMed - indexed for MEDLINE]Related articles

A double-blind, randomized trial of IV immunoglobulin treatment in acute optic neuritis.

Roed HG, Langkilde A, Sellebjerg F, Lauritzen M, Bang P, Mørup A, Frederiksen JL.

Neurology. 2005 Mar 8;64(5):804-10.PMID: 15753413 [PubMed - indexed for MEDLINE]Related articles

Responsiveness of the Multiple Sclerosis Impairment Scale in comparison with the Expanded Disability Status Scale.

Ravnborg M, Blinkenberg M, Sellebjerg F, Ballegaard M, Larsen SH, Sørensen PS.

Mult Scler. 2005 Feb;11(1):81-4.PMID: 15732271 [PubMed - indexed for MEDLINE]Related articles

IV immunoglobulins as add-on treatment to methylprednisolone for acute relapses in MS.

Sorensen PS, Haas J, Sellebjerg F, Olsson T, Ravnborg M; TARIMS Study Group.

Neurology. 2004 Dec 14;63(11):2028-33.PMID: 15596745 [PubMed - indexed for MEDLINE]Related articles

Cytokines and adhesion molecules in multiple sclerosis patients treated with interferon-beta1b.

Jensen J, Krakauer M, Sellebjerg F.

Cytokine. 2005 Jan 7;29(1):24-30.PMID: 15579375 [PubMed - indexed for MEDLINE]Related articles

Optic neuritis: chemokine receptor CXCR3 and its ligands.

Sørensen TL, Roed H, Sellebjerg F.

Br J Ophthalmol. 2004 Sep;88(9):1146-8.PMID: 15317705 [PubMed - indexed for MEDLINE]Related articlesFree article

Chemokine CCL2 and chemokine receptor CCR2 in early active multiple sclerosis.

Sørensen TL, Ransohoff RM, Strieter RM, Sellebjerg F.

Eur J Neurol. 2004 Jul;11(7):445-9.PMID: 15257681 [PubMed - indexed for MEDLINE]Related articles

CD4 T cell activation and disease activity at onset of multiple sclerosis.

Jensen J, Langkilde AR, Fenst C, Nicolaisen MS, Roed HG, Christiansen M, Sellebjerg F.

J Neuroimmunol. 2004 Apr;149(1-2):202-9.PMID: 15020081 [PubMed - indexed for MEDLINE]Related articles

Chemokines and matrix metalloproteinase-9 in leukocyte recruitment to the central nervous system.

Sellebjerg F, Sørensen TL.

Brain Res Bull. 2003 Aug 15;61(3):347-55. Review.PMID: 12909304 [PubMed - indexed for MEDLINE]Related articles

Gadolinium-enhanced magnetic resonance imaging predicts response to methylprednisolone in multiple sclerosis.

Sellebjerg F, Jensen CV, Larsson HB, Frederiksen JL.

Mult Scler. 2003 Feb;9(1):102-7.PMID: 12617276 [PubMed - indexed for MEDLINE]Related articles

Evidence favoring the involvement of CC chemokine receptor (CCR) 5 in T-lymphocyte accumulation in optic neuritis.

Sørensen TL, Ransohoff RM, Jensen J, Sellebjerg F.

Acta Neurol Scand. 2003 Mar;107(3):221-7.PMID: 12614317 [PubMed - indexed for MEDLINE]Related articles

Expansion of CD5 - B cells in multiple sclerosis correlates with CD80 (B7-1) expression.

Sellebjerg F, Jensen J, Jensen CV, Wiik A.

Scand J Immunol. 2002 Jul;56(1):101-7.PMID: 12100477 [PubMed - indexed for MEDLINE]Related articles

Chemokine receptors on mononuclear phagocytes in the central nervous system of patients with multiple sclerosis.

Trebst C, Sørensen TL, Kivisäkk P, Cathcart MK, Hesselgesser J, Horuk R, Sellebjerg F, Lassmann H, Ransohoff RM.

Ernst Schering Res Found Workshop. 2002;(39):193-211. No abstract available. PMID: 12066413 [PubMed - indexed for MEDLINE]Related articles

Multiple sclerosis: a study of CXCL10 and CXCR3 co-localization in the inflamed central nervous system.

Sørensen TL, Trebst C, Kivisäkk P, Klaege KL, Majmudar A, Ravid R, Lassmann H, Olsen DB, Strieter RM, Ransohoff RM, Sellebjerg F.

J Neuroimmunol. 2002 Jun;127(1-2):59-68.PMID: 12044976 [PubMed - indexed for MEDLINE]Related articles

Selective suppression of chemokine receptor CXCR3 expression by interferon-beta1a in multiple sclerosis.

Sørensen TL, Sellebjerg F.

Mult Scler. 2002 Apr;8(2):104-7.PMID: 11990865 [PubMed - indexed for MEDLINE]Related articles

Cerebrospinal fluid levels of nitric oxide metabolites predict response to methylprednisolone treatment in multiple sclerosis and optic neuritis.

Sellebjerg F, Giovannoni G, Hand A, Madsen HO, Jensen CV, Garred P.

J Neuroimmunol. 2002 Apr;125(1-2):198-203.PMID: 11960657 [PubMed - indexed for MEDLINE]Related articles

Chemokines CXCL10 and CCL2: differential involvement in intrathecal inflammation in multiple sclerosis.

Sørensen TL, Sellebjerg F, Jensen CV, Strieter RM, Ransohoff RM.

Eur J Neurol. 2001 Nov;8(6):665-72.PMID: 11784351 [PubMed - indexed for MEDLINE]Related articles

Chemokine receptor expression on B cells and effect of interferon-beta in multiple sclerosis.

Sørensen TL, Roed H, Sellebjerg F.

J Neuroimmunol. 2002 Jan;122(1-2):125-31.PMID: 11777551 [PubMed - indexed for MEDLINE]Related articles

CCR1+/CCR5+ mononuclear phagocytes accumulate in the central nervous system of patients with multiple sclerosis.

Trebst C, Sørensen TL, Kivisäkk P, Cathcart MK, Hesselgesser J, Horuk R, Sellebjerg F, Lassmann H, Ransohoff RM.

Am J Pathol. 2001 Nov;159(5):1701-10.PMID: 11696431 [PubMed - indexed for MEDLINE]Related articlesFree article

Distinct chemokine receptor and cytokine expression profile in secondary progressive MS.

Sørensen TL, Sellebjerg F.

Neurology. 2001 Oct 23;57(8):1371-6.PMID: 11673573 [PubMed - indexed for MEDLINE]Related articles

Increased T cell expression of CD154 (CD40-ligand) in multiple sclerosis.

Jensen J, Krakauer M, Sellebjerg F.

Eur J Neurol. 2001 Jul;8(4):321-8.PMID: 11422428 [PubMed - indexed for MEDLINE]Related articles